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DK3792378T3 - Fremgangsmåder og anordninger til analyse af partikler - Google Patents

Fremgangsmåder og anordninger til analyse af partikler Download PDF

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Publication number
DK3792378T3
DK3792378T3 DK20197858.2T DK20197858T DK3792378T3 DK 3792378 T3 DK3792378 T3 DK 3792378T3 DK 20197858 T DK20197858 T DK 20197858T DK 3792378 T3 DK3792378 T3 DK 3792378T3
Authority
DK
Denmark
Prior art keywords
particles
analysis
methods
devices
Prior art date
Application number
DK20197858.2T
Other languages
English (en)
Inventor
Jens Huft
Kaston Leung
Anders Klaus
Adi Steif
Carl Lars Genghis Hansen
Loenhout Marinus Theodorus Johannes Van
Bill Kengli Lin
Samuel Alves Jana Rodrigues Aparicio
Sohrab Prakash Shah
Hans Zahn
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of DK3792378T3 publication Critical patent/DK3792378T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/123Flexible; Elastomeric
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/14Means for pressure control

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK20197858.2T 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler DK3792378T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562111755P 2015-02-04 2015-02-04
US201562162039P 2015-05-15 2015-05-15
US201562237690P 2015-10-06 2015-10-06
EP16746018.7A EP3253911B1 (en) 2015-02-04 2016-02-04 Methods and devices for analyzing particles

Publications (1)

Publication Number Publication Date
DK3792378T3 true DK3792378T3 (da) 2023-11-27

Family

ID=56563254

Family Applications (2)

Application Number Title Priority Date Filing Date
DK20197858.2T DK3792378T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler
DK16746018.7T DK3253911T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK16746018.7T DK3253911T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler

Country Status (5)

Country Link
US (3) US10760121B2 (da)
EP (4) EP3253911B1 (da)
CA (1) CA2974632A1 (da)
DK (2) DK3792378T3 (da)
WO (1) WO2016123692A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10017759B2 (en) 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
US10900065B2 (en) 2014-11-14 2021-01-26 University Of Washington Methods and kits for labeling cellular molecules
EP3253911B1 (en) 2015-02-04 2021-01-20 The University Of British Columbia Methods and devices for analyzing particles
EP3472356A4 (en) * 2016-06-17 2019-07-24 Mayo Foundation for Medical Education and Research METHOD AND MATERIALS FOR EFFECTIVELY USING THE COMBINED TARGET ENRICHMENT OF GENOMEGIONS AND FOR TOTAL GENOME SEQUENCING WITH LOW RANGE
US11213824B2 (en) 2017-03-29 2022-01-04 The Research Foundation For The State University Of New York Microfluidic device and methods
JP7019894B2 (ja) * 2017-08-31 2022-02-16 エスゼット ディージェイアイ テクノロジー カンパニー リミテッド 物体を感知する方法及びセンサシステム
CN108363902B (zh) * 2018-01-30 2022-02-25 成都奇恩生物科技有限公司 一种致病遗传变异的精确预测方法
EP3749740B1 (en) * 2018-02-05 2023-08-30 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for multiplexed measurements in single and ensemble cells
MX2020009639A (es) 2018-03-16 2021-01-08 Zoetis Services Llc Vacunas de peptídos contra interleucina-31.
WO2019177697A2 (en) 2018-03-16 2019-09-19 Zoetis Services Llc Interleukin-31 monoclonal antibodies for veterinary use
WO2019217099A1 (en) * 2018-05-08 2019-11-14 President And Fellows Of Harvard College Droplet-based single cell genomic dna sequencing
WO2020006183A1 (en) * 2018-06-28 2020-01-02 10X Genomics, Inc. Systems and methods for visualization of single-cell resolution characteristics
RU2763555C2 (ru) * 2018-06-29 2021-12-30 Иллюмина, Инк. Проточные ячейки
CN113557090B (zh) * 2019-03-18 2024-03-22 赛卢拉研究公司 成分进入流体的精确递送
EP4010481A4 (en) 2019-08-09 2023-09-20 Nutcracker Therapeutics, Inc. MICROFLUIDIC DEVICES AND METHODS OF USE THEREOF
WO2021097456A1 (en) * 2019-11-17 2021-05-20 The Regents Of The University Of California Guided Microfluidic Flow for Cell Capture, Indexing, and Directed Release
US20230220501A1 (en) * 2022-01-13 2023-07-13 Whitworth University Pathogen detection system
WO2023172860A1 (en) * 2022-03-07 2023-09-14 Cedars-Sinai Medical Center Method for detecting cancer and tumor invasiveness using dna palindromes as a biomarker

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2360234B1 (en) * 2001-11-30 2015-07-22 Fluidigm Corporation Microfluidic device and methods of using same
EP2212437A4 (en) 2007-11-07 2011-09-28 Univ British Columbia MICROFLUIDIC DEVICE AND METHOD OF USING THE DEVICE
US9080211B2 (en) 2008-10-24 2015-07-14 Epicentre Technologies Corporation Transposon end compositions and methods for modifying nucleic acids
US9188593B2 (en) 2010-07-16 2015-11-17 The University Of British Columbia Methods for assaying cellular binding interactions
DK2630263T4 (da) * 2010-10-22 2022-02-14 Cold Spring Harbor Laboratory Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier
CN102533960B (zh) * 2010-12-31 2014-04-30 深圳华大基因科技有限公司 一种单细胞基因组分析方法及试剂盒
US9902990B2 (en) 2011-05-27 2018-02-27 The University Of British Columbia Microfluidic cell trap and assay apparatus for high-throughput analysis
US10017759B2 (en) * 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
WO2016115537A2 (en) * 2015-01-15 2016-07-21 Massachusetts Institute Of Technology Systems, methods, and apparatus for in vitro single-cell identification and recovery
EP3253911B1 (en) 2015-02-04 2021-01-20 The University Of British Columbia Methods and devices for analyzing particles

Also Published As

Publication number Publication date
WO2016123692A1 (en) 2016-08-11
EP3792378B1 (en) 2023-08-23
US20180010179A1 (en) 2018-01-11
EP3253911B1 (en) 2021-01-20
US11434530B2 (en) 2022-09-06
US20230091562A1 (en) 2023-03-23
DK3253911T3 (da) 2021-04-06
EP4273262A3 (en) 2023-12-27
EP3792378A1 (en) 2021-03-17
US20200332357A1 (en) 2020-10-22
EP3253911A4 (en) 2018-07-04
EP4450635A2 (en) 2024-10-23
EP3253911A1 (en) 2017-12-13
EP4273262A2 (en) 2023-11-08
US10760121B2 (en) 2020-09-01
CA2974632A1 (en) 2016-08-11

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