DK3169703T4 - Kimær antigenreceptor og anvendelse deraf - Google Patents

Kimær antigenreceptor og anvendelse deraf Download PDF

Info

Publication number: DK3169703T4
Authority: DK; Denmark
Prior art keywords: antigen receptor; chimeric antigen; chimeric; receptor; antigen
Prior art date: 2014-07-16

Application number

DK15738356.3T

Other languages

English (en)

Other versions

DK3169703T3 (da

Inventor

Hinrich Abken

Andreas Hombach

Original Assignee

Hinrich Abken

Andreas Hombach

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-07-16

Filing date

2015-07-16

Publication date

2024-02-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51178778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3169703(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-07-16 Application filed by Hinrich Abken, Andreas Hombach filed Critical Hinrich Abken

2020-11-16 Publication of DK3169703T3 publication Critical patent/DK3169703T3/da

2024-02-26 Application granted granted Critical

2024-02-26 Publication of DK3169703T4 publication Critical patent/DK3169703T4/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Cell Biology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Zoology (AREA)
Oncology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

DK15738356.3T 2014-07-16 2015-07-16 Kimær antigenreceptor og anvendelse deraf DK3169703T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP14177278		2014-07-16
PCT/EP2015/066252 WO2016008973A1 (en)	2014-07-16	2015-07-16	Chimeric antigen receptor and its use

Publications (2)

Publication Number	Publication Date
DK3169703T3 DK3169703T3 (da)	2020-11-16
DK3169703T4 true DK3169703T4 (da)	2024-02-26

Family

ID=51178778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK15738356.3T DK3169703T4 (da)	2014-07-16	2015-07-16	Kimær antigenreceptor og anvendelse deraf

Country Status (6)

Country	Link
US (2)	US10865243B2 (da)
EP (1)	EP3169703B2 (da)
DK (1)	DK3169703T4 (da)
ES (1)	ES2833162T5 (da)
FI (1)	FI3169703T4 (da)
WO (1)	WO2016008973A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2905557T3 (es)	2013-08-26	2022-04-11	Hinrich Abken	Receptor de antígeno quimérico anti-CD30 y su uso
CA2976089A1 (en)	2015-02-10	2016-08-18	Minerva Biotechnologies Corporation	Humanized anti-muc1* antibodies
EP3098237B1 (en) *	2015-05-28	2018-08-01	Universität Zu Köln	Anti-toso chimeric antigen receptor and its use
CN109705211B (zh) *	2017-10-26	2020-08-18	苏州复融生物技术有限公司	一种IgG1 Fc单体及其应用
GB201721833D0 (en) *	2017-12-22	2018-02-07	Cancer Research Tech Ltd	Fusion proteins
JP2021518149A (ja) *	2018-03-26	2021-08-02	オリジンセルセラピューティクスカンパニーリミテッド	免疫細胞増殖を促進する方法
WO2019240934A1 (en) *	2018-06-12	2019-12-19	Promab Biotechnologies, Inc.	Plap-car-effector cells
CN113227147B (zh) *	2018-12-24	2022-07-19	信达生物制药(苏州)有限公司	全人源的抗cd30单链抗体及其应用
WO2020135559A1 (en) *	2018-12-26	2020-07-02	Nanjing Legend Biotech Co., Ltd.	Cd30-binding moieties, chimeric antigen receptors, and uses thereof
EP3747904A1 (en) *	2019-06-03	2020-12-09	Universität Regensburg	Cd25-specific chimeric antigen receptors and their uses
WO2021221927A1 (en)	2020-04-27	2021-11-04	Parsons Corporation	Narrowband iq signal obfuscation
WO2021245249A1 (en)	2020-06-05	2021-12-09	Tessa Therapeutics Ltd.	Treatment of cd30-positive cancer
AR124414A1 (es)	2020-12-18	2023-03-22	Century Therapeutics Inc	Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
CN117015456A (zh)	2021-02-08	2023-11-07	艾沛克斯品牌公司	具有远端接合区域的螺栓提取器
WO2022232797A2 (en)	2021-04-27	2022-11-03	Baylor College Of Medicine	Virus-specific immune cells expressing chimeric antigen receptors
US11945876B2 (en)	2021-06-16	2024-04-02	Instil Bio (Uk) Limited	Receptors providing targeted costimulation for adoptive cell therapy
TW202321443A (zh)	2021-10-26	2023-06-01	新加坡商泰莎治療有限公司	用於生產編碼car之反轉錄病毒載體的細胞株
WO2023104910A1 (en)	2021-12-08	2023-06-15	Tessa Therapeutics Ltd.	Treatment of lymphoma
WO2023198744A1 (en)	2022-04-13	2023-10-19	Tessa Therapeutics Ltd.	Therapeutic t cell product
WO2024165024A1 (zh) *	2023-02-09	2024-08-15	星尘生物科技(上海)有限公司	一种嵌合抗原受体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR112013018317A2 (pt) *	2010-12-23	2017-03-21	Janssen Biotech Inc	mutantes de fc do anticorpo resistentes a protease ativa
EP3594245A1 (en)	2012-02-13	2020-01-15	Seattle Children's Hospital d/b/a Seattle Children's Research Institute	Bispecific chimeric antigen receptors and therapeutic uses thereof
US20130280220A1 (en)	2012-04-20	2013-10-24	Nabil Ahmed	Chimeric antigen receptor for bispecific activation and targeting of t lymphocytes
ES2905557T3 (es) *	2013-08-26	2022-04-11	Hinrich Abken	Receptor de antígeno quimérico anti-CD30 y su uso

2015
- 2015-07-16 EP EP15738356.3A patent/EP3169703B2/en active Active
- 2015-07-16 ES ES15738356T patent/ES2833162T5/es active Active
- 2015-07-16 FI FIEP15738356.3T patent/FI3169703T4/fi active
- 2015-07-16 WO PCT/EP2015/066252 patent/WO2016008973A1/en active Application Filing
- 2015-07-16 DK DK15738356.3T patent/DK3169703T4/da active
- 2015-07-16 US US15/325,638 patent/US10865243B2/en active Active
2020
- 2020-11-12 US US17/096,192 patent/US20220002401A1/en active Pending

Also Published As

Publication number	Publication date
EP3169703B2 (en)	2023-12-13
FI3169703T4 (fi)	2024-03-01
EP3169703B1 (en)	2020-09-02
EP3169703A1 (en)	2017-05-24
US20170145095A1 (en)	2017-05-25
ES2833162T5 (es)	2024-06-12
US10865243B2 (en)	2020-12-15
US20220002401A1 (en)	2022-01-06
ES2833162T3 (es)	2021-06-14
DK3169703T3 (da)	2020-11-16
WO2016008973A1 (en)	2016-01-21

Publication	Publication Date	Title
DK3169703T4 (da)	2024-02-26	Kimær antigenreceptor og anvendelse deraf
DK3227336T3 (da)	2019-09-16	Anti-CD79b-antistoffer og fremgangsmåder til anvendelse
CL2016002196A1 (es)	2018-02-16	Receptor antigénico quimérico
DK3333191T3 (da)	2020-10-26	Anti-C10ORF54-antistoffer og anvendelser deraf
IL252295A0 (en)	2017-07-31	Chimeric antigen receptors and methods of using them
DK3126388T3 (da)	2019-07-29	Anti-EGFRvIII-antistoffer og anvendelser deraf
DK3365364T5 (da)	2024-09-30	Kimære antistof/T-celle-receptorkonstruktioner og anvendelser deraf
DK3546572T3 (da)	2024-05-06	CD19-specifik kimær antigenreceptor og anvendelser deraf
DK3227339T3 (da)	2022-01-10	Kimæriske antigenreceptorer rettet mod g-protein-koblet receptor og anvendelser deraf
DK3514172T3 (da)	2020-04-06	Claudin-6-specifikke immunoreceptorer og t-celleepitoper
DK3258951T3 (da)	2020-04-06	Anti-pvrig antistoffer og fremgangsmåder for anvendelse
DK3149042T3 (da)	2019-11-04	PD-L1-antistoffer og anvendelser deraf
DK3280441T3 (da)	2021-11-15	Anti-sortilin-antistoffer og fremgangsmåder til anvendelse deraf
DK3309174T3 (da)	2022-06-07	ANTI-PD-L1-antistoffer og diagnostiske anvendelser deraf
DK3215532T3 (da)	2020-01-02	Anti-TIM3-antistoffer og fremgangsmåder til anvendelse
DK3575315T3 (da)	2022-12-19	Kimære antigenreceptorer
DK3191135T3 (da)	2020-10-12	Anti-HER2-antistoffer og immunokonjugater
DK3107938T3 (da)	2022-07-11	Modificerede, antigenbindende polypeptidkonstrukter og anvendelser heraf
DK3212255T3 (da)	2021-03-29	Selvorienterende sprøjte og sprøjtegrænseflade
IL284291A (en)	2021-07-29	Anti-acth antibodies from humans and their use
DK3116911T3 (da)	2019-09-30	Anti-mcam-antistoffer og tilhørende fremgangsmåder til anvendelse
DK3218358T3 (da)	2021-08-30	Ifluorometyl-aminopyridiner og difluorometyl-aminopyrimidiner
DK3018183T3 (da)	2022-12-05	Halogenolefinbaseret sammensætning og anvendelse deraf
DK3113797T3 (da)	2022-07-25	Antistoffer, anvendelser og fremgangsmåder
DK3233903T3 (da)	2021-02-22	Kimære antigenreceptorer og anvendelsesfremgangsmåder