DK28683A - Fremgangsmaade til fremstilling af substituerede urinstoffer og thiourinstoffer - Google Patents

Fremgangsmaade til fremstilling af substituerede urinstoffer og thiourinstoffer Download PDF

Info

Publication number: DK28683A
Authority: DK; Denmark
Prior art keywords: thiour; urines; ingredients; substituted; procedure
Prior art date: 1982-01-26

Application number

DK28683A

Other languages

English (en)

Other versions

DK160869B (da

DK160869C (da

DK28683D0 (da

Inventor

Vern Gordon Devries

Elwood Eugene Largis

Ransom Brown Conrow

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-01-26

Filing date

1983-01-25

Publication date

1983-07-27

1982-01-26 Priority claimed from US06/342,693 external-priority patent/US4473579A/en

1982-01-26 Priority claimed from US06/342,698 external-priority patent/US4387105A/en

1983-01-25 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1983-01-25 Publication of DK28683D0 publication Critical patent/DK28683D0/da

1983-07-27 Publication of DK28683A publication Critical patent/DK28683A/da

1991-04-29 Publication of DK160869B publication Critical patent/DK160869B/da

1991-10-14 Application granted granted Critical

1991-10-14 Publication of DK160869C publication Critical patent/DK160869C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
- C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
- C07C273/1827—X being H
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Furan Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK028683A 1982-01-26 1983-01-25 Analogifremgangsmaade til fremstilling af substituerede urinstoffer og thiourinstoffer DK160869C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US34269882		1982-01-26
US06/342,693 US4473579A (en)	1982-01-26	1982-01-26	Antiatherosclerotic tetrasubstituted ureas and thioureas
US34269382		1982-01-26
US06/342,698 US4387105A (en)	1982-01-26	1982-01-26	Methods of treating atherosclerosis with dialkylureas and dialkylthioureas

Publications (4)

Publication Number	Publication Date
DK28683D0 DK28683D0 (da)	1983-01-25
DK28683A true DK28683A (da)	1983-07-27
DK160869B DK160869B (da)	1991-04-29
DK160869C DK160869C (da)	1991-10-14

Family

ID=26993144

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK028683A DK160869C (da)	1982-01-26	1983-01-25	Analogifremgangsmaade til fremstilling af substituerede urinstoffer og thiourinstoffer

Country Status (20)

Country	Link
KR (1)	KR890001808B1 (da)
AT (1)	AT391313B (da)
AU (1)	AU562699B2 (da)
CH (1)	CH654571A5 (da)
DE (1)	DE3247581A1 (da)
DK (1)	DK160869C (da)
ES (2)	ES519246A0 (da)
FI (1)	FI85013C (da)
FR (1)	FR2521134B1 (da)
GB (1)	GB2113684B (da)
GR (1)	GR77186B (da)
HU (1)	HU200746B (da)
IE (1)	IE54683B1 (da)
IL (1)	IL67417A (da)
IT (1)	IT1203647B (da)
NL (1)	NL8300269A (da)
NO (1)	NO158417C (da)
PL (1)	PL143836B1 (da)
PT (1)	PT76138A (da)
SE (1)	SE462653B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2138804A (en) *	1983-04-27	1984-10-31	Sumitomo Chemical Co	Fungicidal N-phenylcarbamates
GB2149394B (en) *	1983-07-19	1986-09-24	American Cyanamid Co	Ureas
US4818899A (en) *	1986-12-03	1989-04-04	Minnesota Mining And Manufacturing Company	Second harmonic generation by carbamic acid derivatives
DE68911203T2 (de) *	1988-03-30	1994-04-14	Warner Lambert Co	N-[[(2,6-disubstituierte)phenyl]N'- arylalkyl] Harnstoffe als antihypercholesterolemische und antiatherosclerotische Mittel.
US5116848A (en) *	1988-03-30	1992-05-26	Warner-Lambert Company	N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
WO1991011994A1 (en) *	1990-02-14	1991-08-22	Chugai Seiyaku Kabushiki Kaisha	Inhibitor of denatured ldl formation
US5668136A (en) *	1990-09-25	1997-09-16	Eisai Co., Ltd.	Trisubstituted benzene derivatives, composition and methods of treatment
HUT62558A (en) *	1991-07-01	1993-05-28	Sandoz Ag	Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same
CA2115915A1 (en) *	1992-07-20	1994-02-03	Kenji Hayashi	Benzene derivatives
AU8534198A (en) *	1997-08-05	1999-03-01	Novo Nordisk A/S	Derivatives of 2,5- and 3,5-disubstituted anilines, their preparation and use
US6455566B1 (en)	1997-09-03	2002-09-24	Wyeth	Substituted 1-aryl-3-heteroaryl-thioureas (or isothioureas) as antiatherosclerotic agents
TW415942B (en) *	1997-09-03	2000-12-21	American Home Prod	Novel substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents
JP2001501979A (ja) *	1998-01-21	2001-02-13	ザイモジェネティクス，インコーポレイティド	カルシトニン擬態物としてのジアルキルウレア
WO2009009122A2 (en) *	2007-07-10	2009-01-15	Amgen Inc.	Derivatives of urea and related diamines, methods for their manufacture, and uses therefor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL92838C (da) *	1949-12-06
US2688039A (en) *	1952-02-08	1954-08-31	Ciba Pharm Prod Inc	Halogen-containing di-(substituted phenyl)-thioureas
US3326663A (en) *	1964-09-25	1967-06-20	Shell Oil Co	Herbicidal phenylureas
US3335142A (en) *	1965-07-07	1967-08-08	American Cyanamid Co	Process for the preparation of n, n'-disubstituted ureas
US3659012A (en) *	1969-05-26	1972-04-25	Lilly Co Eli	Methods of treating helminth infections with thiourea derivatives
US3728386A (en) *	1970-07-27	1973-04-17	Exxon Research Engineering Co	N-cycloalkylalkyl and n-cycloalkyl substituted phenyl ureas and halo acetamides
US3928437A (en) *	1970-09-02	1975-12-23	Ciba Geigy Corp	Phenoxy-phenyl, phenylthiophenyl, phenylsulfonylphenyl and phenylaminophenyl diaminothioureas
US3856952A (en) *	1973-03-01	1974-12-24	Pennwalt Corp	Synergistic antimicrobial compositions employing certain n-(phenyl-carbamyl)amino-benzene sulfonyl flourides
US3903130A (en) *	1974-05-03	1975-09-02	Stauffer Chemical Co	1-Trifluormethylphenyl-3-dicyanophenyl urea
DE2928485A1 (de) *	1979-07-14	1981-01-29	Bayer Ag	Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen

1982
- 1982-12-05 IL IL67417A patent/IL67417A/xx not_active IP Right Cessation
- 1982-12-22 DE DE19823247581 patent/DE3247581A1/de not_active Withdrawn
- 1982-12-28 KR KR8205843A patent/KR890001808B1/ko active
1983
- 1983-01-14 GR GR70261A patent/GR77186B/el unknown
- 1983-01-21 AU AU10681/83A patent/AU562699B2/en not_active Ceased
- 1983-01-24 GB GB08301863A patent/GB2113684B/en not_active Expired
- 1983-01-25 FI FI830247A patent/FI85013C/fi not_active IP Right Cessation
- 1983-01-25 SE SE8300370A patent/SE462653B/sv not_active IP Right Cessation
- 1983-01-25 IE IE146/83A patent/IE54683B1/en not_active IP Right Cessation
- 1983-01-25 AT AT0023983A patent/AT391313B/de not_active IP Right Cessation
- 1983-01-25 DK DK028683A patent/DK160869C/da not_active IP Right Cessation
- 1983-01-25 NO NO830238A patent/NO158417C/no unknown
- 1983-01-25 CH CH404/83A patent/CH654571A5/de not_active IP Right Cessation
- 1983-01-25 IT IT47605/83A patent/IT1203647B/it active
- 1983-01-25 NL NL8300269A patent/NL8300269A/nl not_active Application Discontinuation
- 1983-01-25 FR FR8301082A patent/FR2521134B1/fr not_active Expired
- 1983-01-25 PL PL1983240284A patent/PL143836B1/pl unknown
- 1983-01-25 HU HU83227A patent/HU200746B/hu not_active IP Right Cessation
- 1983-01-25 ES ES519246A patent/ES519246A0/es active Granted
- 1983-01-25 PT PT76138A patent/PT76138A/pt not_active IP Right Cessation
1984
- 1984-04-11 ES ES531508A patent/ES8505943A1/es not_active Expired

Also Published As

Publication number	Publication date
DK160869B (da)	1991-04-29
FI85013B (fi)	1991-11-15
AU1068183A (en)	1983-08-04
SE8300370L (sv)	1983-07-27
HU200746B (en)	1990-08-28
GR77186B (da)	1984-09-11
ES531508A0 (es)	1985-07-01
NO158417B (no)	1988-05-30
SE462653B (sv)	1990-08-06
IT8347605A0 (it)	1983-01-25
GB2113684A (en)	1983-08-10
DK160869C (da)	1991-10-14
KR890001808B1 (ko)	1989-05-23
FR2521134A1 (fr)	1983-08-12
ATA23983A (de)	1990-03-15
ES8406422A1 (es)	1984-08-01
ES519246A0 (es)	1984-08-01
KR840002773A (ko)	1984-07-16
AU562699B2 (en)	1987-06-18
IL67417A (en)	1989-10-31
SE8300370D0 (sv)	1983-01-25
FI85013C (fi)	1992-02-25
NL8300269A (nl)	1983-08-16
PL240284A1 (en)	1985-01-02
NO158417C (no)	1988-09-07
IE54683B1 (en)	1990-01-03
NO830238L (no)	1983-07-27
CH654571A5 (de)	1986-02-28
AT391313B (de)	1990-09-25
GB8301863D0 (en)	1983-02-23
PT76138A (en)	1983-02-01
PL143836B1 (en)	1988-03-31
GB2113684B (en)	1985-12-18
FR2521134B1 (fr)	1987-01-09
IE830146L (en)	1983-07-26
DE3247581A1 (de)	1983-08-04
FI830247L (fi)	1983-07-27
DK28683D0 (da)	1983-01-25
ES8505943A1 (es)	1985-07-01
FI830247A0 (fi)	1983-01-25
IT1203647B (it)	1989-02-15

Publication	Publication Date	Title
DK1183A (da)	1983-07-08	Fremgangsmaade til fremstilling af tiazolidinderivater
DK573083D0 (da)	1983-12-13	Engangsble og fremgangsmaade til fremstilling af denne
DK28683A (da)	1983-07-27	Fremgangsmaade til fremstilling af substituerede urinstoffer og thiourinstoffer
DK299284A (da)	1985-01-27	Fremgangsmaade til fraktionering af fedt
DK32383D0 (da)	1983-01-27	Phosphinsyrederivater og fremgangsmade til fremstilling af disse
DK309783A (da)	1984-01-09	Fremgangsmaade til fremstilling af organoglykosider
NO156383C (no)	1987-09-09	Vernegitter e.l. og framgangsmte for tilvirking av dette.
DK119083D0 (da)	1983-03-14	Fremgangsmade til fremstilling af alkanoylpyridinoner
DK47684A (da)	1984-08-23	Fremgangsmaade til fremstilling af proteinhydrolysater
DK149944C (da)	1987-06-22	Polymert dispergeringsmiddel og fremgangsmaader til fremstilling af samme
DK287484D0 (da)	1984-06-12	Fremgangsmaade til fremstilling af acetaldehyd
DK33181A (da)	1981-08-07	Fremgangsmaade til fremstilling af et interferonlignende protein
DK96881A (da)	1981-09-06	Fremgangsmaade til fremstilling af et angiotensinomdannende enzym
DK185683D0 (da)	1983-04-26	Fremgangsmade til fremstilling af pleuromutilinderivater
DK424083A (da)	1984-03-29	Fremgangsmaade til fremstilling af anthracyclinglycosider
DK296383A (da)	1983-12-30	Fremgangsmaade til fremstilling af fenaetylaminer
DK440281A (da)	1982-04-07	Fremgangsmaade til fremstilling af n-carboxylalkyldipeptider og derivater deraf
DK151274C (da)	1988-06-20	Fremgangsmaade til fremstilling af meldroejealkaloider, isaer ergokornin og beta-ergokryptin
DK175290D0 (da)	1990-07-23	Fremgangsmaade til fremstilling af azetidinoner
DK296883D0 (da)	1983-06-28	Fremgangsmade til fremstilling af eburnanoximaetere
DK62283A (da)	1983-08-13	Fremgangsmaade til fremstilling af peptidergotalkaloider
DK219483A (da)	1983-11-25	Fremgangsmaade til fremstilling af anthracyclinglycosider
DK9383A (da)	1983-07-13	Fremgangsmaade til fremstilling af phosphinoxider
DK157874C (da)	1990-07-30	Fremgangsmaade til fremstilling af azinomethylrifamyciner
DK290682A (da)	1982-12-30	Fremgangsmaade til fremstilling af 24-cyclopropylcholen-3beta,22-dioler og estere deraf

Legal Events

Date	Code	Title	Description
1996-09-16	PBP	Patent lapsed