DK177489D0 - CHOLESTA STATE DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES - Google Patents

CHOLESTA STATE DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Info

Publication number: DK177489D0
Authority: DK; Denmark
Prior art keywords: derivatives; homovitamin; cholesta; intermediates; preparation
Prior art date: 1984-10-04

Application number

DK177489A

Other languages

Danish (da)

Other versions

DK158989B (en

DK158989C (en

DK177489A (en

Inventor

Hector F Deluca

Nobuo Ikekawa

Yoko Tanaka

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-04

Filing date

1989-04-13

Publication date

1989-04-13

1989-04-13 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1989-04-13 Publication of DK177489D0 publication Critical patent/DK177489D0/en

1989-04-13 Publication of DK177489A publication Critical patent/DK177489A/en

1990-08-13 Publication of DK158989B publication Critical patent/DK158989B/en

1991-01-21 Application granted granted Critical

1991-01-21 Publication of DK158989C publication Critical patent/DK158989C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK177489A 1984-10-04 1989-04-13 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES DK158989C (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US65754984A	1984-10-04	1984-10-04
US65754984		1984-10-04
PCT/US1985/001571 WO1986002078A1 (en)	1984-10-04	1985-08-19	Vitamin d derivatives and methods for preparing same
US8501571		1985-08-19

Publications (4)

Publication Number	Publication Date
DK177489D0 true DK177489D0 (en)	1989-04-13
DK177489A DK177489A (en)	1989-04-13
DK158989B DK158989B (en)	1990-08-13
DK158989C DK158989C (en)	1991-01-21

Family

ID=24637652

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
DK260086A DK154290C (en)	1984-10-04	1986-06-03	VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
DK111188A DK159389C (en)	1984-10-04	1988-03-02	CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES
DK177489A DK158989C (en)	1984-10-04	1989-04-13	CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015290A DK158990C (en)	1984-10-04	1990-01-19	CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015390A DK158991C (en)	1984-10-04	1990-01-19	CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DK260086A DK154290C (en)	1984-10-04	1986-06-03	VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
DK111188A DK159389C (en)	1984-10-04	1988-03-02	CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DK015290A DK158990C (en)	1984-10-04	1990-01-19	CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015390A DK158991C (en)	1984-10-04	1990-01-19	CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Country Status (13)

Country	Link
EP (1)	EP0197949A1 (en)
JP (3)	JPS62500301A (en)
AU (2)	AU582789B2 (en)
BE (1)	BE903376A (en)
CH (1)	CH672920A5 (en)
DE (2)	DE3590488T (en)
DK (5)	DK154290C (en)
FR (1)	FR2571369B1 (en)
GB (2)	GB2167070B (en)
IE (1)	IE58104B1 (en)
IT (1)	IT1190401B (en)
NL (1)	NL8520265A (en)
WO (1)	WO1986002078A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5206229A (en) *	1988-04-21	1993-04-27	Leo Pharmaceutical Products Ltd	Vitamin d analogues
NL8920392A (en) *	1988-04-29	1990-04-02	Wisconsin Alumni Res Found	1FA-HYDROXYVITAMINE D-HOMOLOGISTS WITH UNSATURATED SIDE CHAIN.
US4927815A (en) *	1988-04-29	1990-05-22	Wisconsin Alumni Research Foundation	Compounds effective in inducing cell differentiation and process for preparing same
US5063221A (en) *	1989-04-05	1991-11-05	Chugai Seiyaku Kabushiki Kaisha	Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (en) *	1989-10-02	1991-04-11	Schering Ag	24-HOMO-VITAMIN-D DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5891865A (en) *	1996-10-04	1999-04-06	Wisconsin Alumni Research Foundation	Treatment of arthritic disease induced by infectious agents
AU2005303773A1 (en)	2004-11-12	2006-05-18	Bioxell Spa	Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3833622A (en) *	1969-03-17	1974-09-03	Upjohn Co	Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) *	1974-05-24	1975-04-29	Wisconsin Alumni Res Found	1,25-Dihydroxyergocalciferol
AU527805B2 (en) *	1978-07-27	1983-03-24	Research Institute For Medicine And Chemistry Inc.	1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) *	1978-10-13	1980-09-30	Wisconsin Alumni Research Foundation	Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) *	1982-09-20	1984-05-15	Wisconsin Alumni Research Foundation	Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) *	1983-03-21	1985-04-02	Hoffmann-La Roche Inc.	Synthesis of 1α,25-dihydroxyergocalciferol
CH665834A5 (en) *	1983-05-09	1988-06-15	Wisconsin Alumni Res Found	METHOD FOR PRODUCING 1ALPHA, 25-DIHYDROXYLATED VITAMIN D (2) AND RELATED COMPOUNDS.

1985
- 1985-08-19 DE DE19853590488 patent/DE3590488T/en active Pending
- 1985-08-19 EP EP85904336A patent/EP0197949A1/en not_active Withdrawn
- 1985-08-19 DE DE3590488A patent/DE3590488C2/de not_active Expired - Lifetime
- 1985-08-19 JP JP60503924A patent/JPS62500301A/en active Granted
- 1985-08-19 CH CH2351/86A patent/CH672920A5/de not_active IP Right Cessation
- 1985-08-19 NL NL8520265A patent/NL8520265A/en unknown
- 1985-08-19 WO PCT/US1985/001571 patent/WO1986002078A1/en active Application Filing
- 1985-08-19 AU AU47761/85A patent/AU582789B2/en not_active Ceased
- 1985-10-04 GB GB08524479A patent/GB2167070B/en not_active Expired
- 1985-10-04 BE BE0/215682A patent/BE903376A/en not_active IP Right Cessation
- 1985-10-04 IE IE244385A patent/IE58104B1/en not_active IP Right Cessation
- 1985-10-04 IT IT22359/85A patent/IT1190401B/en active
- 1985-10-04 FR FR8514758A patent/FR2571369B1/en not_active Expired
1986
- 1986-06-03 DK DK260086A patent/DK154290C/en active
1987
- 1987-04-23 GB GB08709579A patent/GB2188932B/en not_active Expired
1988
- 1988-03-02 DK DK111188A patent/DK159389C/en active
- 1988-12-29 AU AU27614/88A patent/AU605007B2/en not_active Ceased
1989
- 1989-04-13 DK DK177489A patent/DK158989C/en active
1990
- 1990-01-19 DK DK015290A patent/DK158990C/en active
- 1990-01-19 DK DK015390A patent/DK158991C/en active
1992
- 1992-05-19 JP JP4150045A patent/JPH0689022B2/en not_active Expired - Lifetime
- 1992-05-19 JP JP4150044A patent/JPH0635475B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH0689022B2 (en)	1994-11-09
DK154290C (en)	1989-03-28
DK158989B (en)	1990-08-13
GB8524479D0 (en)	1985-11-06
JPH05178887A (en)	1993-07-20
JPH0569103B2 (en)	1993-09-30
IE852443L (en)	1986-04-04
DK159389B (en)	1990-10-08
JPS62500301A (en)	1987-02-05
DK260086D0 (en)	1986-06-03
WO1986002078A1 (en)	1986-04-10
AU2761488A (en)	1989-06-08
DK111188A (en)	1988-03-02
GB2188932B (en)	1988-09-01
DK158989C (en)	1991-01-21
JPH05222089A (en)	1993-08-31
JPH0635475B2 (en)	1994-05-11
DE3590488T (en)	1986-10-09
IE58104B1 (en)	1993-06-30
DK154290B (en)	1988-10-31
FR2571369A1 (en)	1986-04-11
DK260086A (en)	1986-06-03
DK177489A (en)	1989-04-13
IT1190401B (en)	1988-02-16
AU605007B2 (en)	1991-01-03
GB2167070B (en)	1988-09-01
AU4776185A (en)	1986-04-17
DE3590488C2 (en)	1992-10-01
IT8522359A0 (en)	1985-10-04
DK111188D0 (en)	1988-03-02
DK158991C (en)	1991-01-21
AU582789B2 (en)	1989-04-13
DK158991B (en)	1990-08-13
DK158990C (en)	1991-01-21
FR2571369B1 (en)	1987-12-04
CH672920A5 (en)	1990-01-15
DK159389C (en)	1991-03-11
DK15390D0 (en)	1990-01-19
DK15390A (en)	1990-01-19
DK15290D0 (en)	1990-01-19
GB2167070A (en)	1986-05-21
EP0197949A1 (en)	1986-10-22
GB2188932A (en)	1987-10-14
NL8520265A (en)	1986-09-01
DK15290A (en)	1990-01-19
BE903376A (en)	1986-02-03
DK158990B (en)	1990-08-13
GB8709579D0 (en)	1987-05-28

Publication	Publication Date	Title
DK335686A (en)	1987-02-25	PROCEDURE FOR THE PREPARATION OF 1-CARBA-3-CEPHEM-4-CARBOXYLIC ACID AND DERIVATIVES THEREOF, AND INTERMEDIATES FOR USING THE PROCEDURE
DK162443C (en)	1992-03-23	1,3-DIACYL-2-OXINDOL COMPOUNDS AND 1-ACYL-2-OXINDOL COMPOUNDS FOR USE AS INTERMEDIATES IN THEIR PREPARATION
DK184588D0 (en)	1988-04-06	INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLERED VITAMIN D2 DERIVATIVES
DK165984C (en)	1993-07-19	PROCEDURE FOR THE PREPARATION OF SPHINGOSIN DERIVATIVES
DK177489D0 (en)	1989-04-13	CHOLESTA STATE DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK214585D0 (en)	1985-05-14	PROCEDURE FOR THE PREPARATION OF IMIDAZORIFAMYCINES
NO851758L (en)	1985-11-04	PROCEDURE FOR THE PREPARATION OF ISOKINOLINE DERIVATIVES
DK56490D0 (en)	1990-03-05	HOMOCHOL STANDARD DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF 26-HOMOVITAMIN D3 DERIVATIVES
NO851638L (en)	1985-10-28	PROCEDURE FOR THE PREPARATION OF IMINOTHIAZOLIDINE DERIVATIVES
DK437287D0 (en)	1987-08-21	2,3-DIHYDROFURAND DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INTERMEDIATES FOR THE PREPARATION OF TETRAHYDROFURAND DERIVATIVES
DK559786D0 (en)	1986-11-21	INTERMEDIATES FOR THE PREPARATION OF BETA-LACTAMANTIBIOTICS
DK422382A (en)	1983-01-03	OXIRANS USED AS INTERMEDIATES IN THE PREPARATION OF SUBSTITUTED 2-HYDROXY-3-AZOLYL PROPANDER DERIVATIVES
DK422582A (en)	1983-01-03	OXIRANS USED AS INTERMEDIATES IN THE PREPARATION OF SUBSTITUTED 1-AZOLYL-2-HYDROXY ALKANDER DERIVATIVES
DK145685D0 (en)	1985-04-01	PROCEDURE FOR THE PREPARATION OF 4-ACETYLIMIDAZOLD DERIVATIVES AND INTERMEDIATES FOR USING THE PROCEDURE
NO166081C (en)	1991-05-29	INTERMEDIATES FOR USE IN THE PREPARATION OF IMIDAZOKINOLIN DERIVATIVES
NO166082C (en)	1991-05-29	INTERMEDIATES FOR USE IN THE PREPARATION OF IMIDAZOKINOLINON DERIVATIVES.
DK291785A (en)	1985-12-30	PROCEDURE FOR THE PREPARATION OF IMINDER DERIVATIVES
DK321484D0 (en)	1984-06-29	STEFFIMYCINON ANALOGUE AND ITS PREPARATION, INTERMEDIATES FOR USE IN THE PREPARATION AND USE OF THE STEFFIMYCINON ANALOGUE AS ANTIBACTERIAL AGENTS AND FOR THE SYNTHESIS OF ANTITUUM AGENTS
DK564985D0 (en)	1985-12-05	PROCEDURE FOR THE PREPARATION OF ALKYLTHIOACETAMIDINES
DK87285A (en)	1985-08-28	PROCEDURE FOR THE PREPARATION OF 3-METHYL-7-FLUORO-5-NITROBENZOTHIOPHY
NO168472C (en)	1992-02-26	SUBSTITUTED CYANOMETHYLBENZAMIDE COMPOUNDS SUITABLE FOR USE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY EFFECTIVE BENZAMIDE COMPOUNDS
DK64085A (en)	1985-08-14	PROCEDURE FOR THE PREPARATION OF IMIDAZOLD DERIVATIVES
NO905385D0 (en)	1990-12-13	TIAZOLD DERIVATIVES SUITABLE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY ACTIVE MONOSULFACTURES.
DK144698C (en)	1982-11-15	2,4-DIAMINO-6-HALOGEN-5-BENZYLPYRIMIDINES USED AS INTERMEDIATES IN THE PREPARATION OF 2,4-DIAMINO-5-BENZYLPYRIMIDINES