Nothing Special   »   [go: up one dir, main page]

DK177489D0 - Cholestadienderivater som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater - Google Patents

Cholestadienderivater som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater

Info

Publication number
DK177489D0
DK177489D0 DK177489A DK177489A DK177489D0 DK 177489 D0 DK177489 D0 DK 177489D0 DK 177489 A DK177489 A DK 177489A DK 177489 A DK177489 A DK 177489A DK 177489 D0 DK177489 D0 DK 177489D0
Authority
DK
Denmark
Prior art keywords
derivatives
homovitamin
cholesta
intermediates
preparation
Prior art date
Application number
DK177489A
Other languages
English (en)
Other versions
DK158989B (da
DK158989C (da
DK177489A (da
Inventor
Hector F Deluca
Nobuo Ikekawa
Yoko Tanaka
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK177489D0 publication Critical patent/DK177489D0/da
Publication of DK177489A publication Critical patent/DK177489A/da
Publication of DK158989B publication Critical patent/DK158989B/da
Application granted granted Critical
Publication of DK158989C publication Critical patent/DK158989C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK177489A 1984-10-04 1989-04-13 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater DK158989C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65754984A 1984-10-04 1984-10-04
US65754984 1984-10-04
PCT/US1985/001571 WO1986002078A1 (en) 1984-10-04 1985-08-19 Vitamin d derivatives and methods for preparing same
US8501571 1985-08-19

Publications (4)

Publication Number Publication Date
DK177489D0 true DK177489D0 (da) 1989-04-13
DK177489A DK177489A (da) 1989-04-13
DK158989B DK158989B (da) 1990-08-13
DK158989C DK158989C (da) 1991-01-21

Family

ID=24637652

Family Applications (5)

Application Number Title Priority Date Filing Date
DK260086A DK154290C (da) 1984-10-04 1986-06-03 Vitamin-d-derivater og farmaceutiske praeparater indeholdende disse
DK111188A DK159389C (da) 1984-10-04 1988-03-02 Cholestadien- eller -trienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af 24-homovitamin-d3-derivater
DK177489A DK158989C (da) 1984-10-04 1989-04-13 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater
DK015290A DK158990C (da) 1984-10-04 1990-01-19 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater
DK015390A DK158991C (da) 1984-10-04 1990-01-19 Cholestadienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK260086A DK154290C (da) 1984-10-04 1986-06-03 Vitamin-d-derivater og farmaceutiske praeparater indeholdende disse
DK111188A DK159389C (da) 1984-10-04 1988-03-02 Cholestadien- eller -trienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af 24-homovitamin-d3-derivater

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK015290A DK158990C (da) 1984-10-04 1990-01-19 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater
DK015390A DK158991C (da) 1984-10-04 1990-01-19 Cholestadienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater

Country Status (13)

Country Link
EP (1) EP0197949A1 (da)
JP (3) JPS62500301A (da)
AU (2) AU582789B2 (da)
BE (1) BE903376A (da)
CH (1) CH672920A5 (da)
DE (2) DE3590488T (da)
DK (5) DK154290C (da)
FR (1) FR2571369B1 (da)
GB (2) GB2167070B (da)
IE (1) IE58104B1 (da)
IT (1) IT1190401B (da)
NL (1) NL8520265A (da)
WO (1) WO1986002078A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206229A (en) * 1988-04-21 1993-04-27 Leo Pharmaceutical Products Ltd Vitamin d analogues
NL8920392A (nl) * 1988-04-29 1990-04-02 Wisconsin Alumni Res Found 1alfa-hydroxyvitamine d-homologen met onverzadigde zijketen.
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5063221A (en) * 1989-04-05 1991-11-05 Chugai Seiyaku Kabushiki Kaisha Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
AU2005303773A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU527805B2 (en) * 1978-07-27 1983-03-24 Research Institute For Medicine And Chemistry Inc. 1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
CH665834A5 (de) * 1983-05-09 1988-06-15 Wisconsin Alumni Res Found Verfahren zur herstellung von 1alpha,25-dihydroxyliertem vitamin d(2) und verwandten verbindungen.

Also Published As

Publication number Publication date
JPH0689022B2 (ja) 1994-11-09
DK154290C (da) 1989-03-28
DK158989B (da) 1990-08-13
GB8524479D0 (en) 1985-11-06
JPH05178887A (ja) 1993-07-20
JPH0569103B2 (da) 1993-09-30
IE852443L (en) 1986-04-04
DK159389B (da) 1990-10-08
JPS62500301A (ja) 1987-02-05
DK260086D0 (da) 1986-06-03
WO1986002078A1 (en) 1986-04-10
AU2761488A (en) 1989-06-08
DK111188A (da) 1988-03-02
GB2188932B (en) 1988-09-01
DK158989C (da) 1991-01-21
JPH05222089A (ja) 1993-08-31
JPH0635475B2 (ja) 1994-05-11
DE3590488T (de) 1986-10-09
IE58104B1 (en) 1993-06-30
DK154290B (da) 1988-10-31
FR2571369A1 (fr) 1986-04-11
DK260086A (da) 1986-06-03
DK177489A (da) 1989-04-13
IT1190401B (it) 1988-02-16
AU605007B2 (en) 1991-01-03
GB2167070B (en) 1988-09-01
AU4776185A (en) 1986-04-17
DE3590488C2 (da) 1992-10-01
IT8522359A0 (it) 1985-10-04
DK111188D0 (da) 1988-03-02
DK158991C (da) 1991-01-21
AU582789B2 (en) 1989-04-13
DK158991B (da) 1990-08-13
DK158990C (da) 1991-01-21
FR2571369B1 (fr) 1987-12-04
CH672920A5 (da) 1990-01-15
DK159389C (da) 1991-03-11
DK15390D0 (da) 1990-01-19
DK15390A (da) 1990-01-19
DK15290D0 (da) 1990-01-19
GB2167070A (en) 1986-05-21
EP0197949A1 (en) 1986-10-22
GB2188932A (en) 1987-10-14
NL8520265A (nl) 1986-09-01
DK15290A (da) 1990-01-19
BE903376A (fr) 1986-02-03
DK158990B (da) 1990-08-13
GB8709579D0 (en) 1987-05-28

Similar Documents

Publication Publication Date Title
DK335686A (da) Fremgangsmaade til fremstilling af 1-carba-3-cephem-4-carboxylsyrer ogderivater deraf samt mellemprodukter til brug ved fremgangsmaaden
DK162443C (da) 1,3-diacyl-2-oxindol-forbindelser samt 1-acyl-2-oxindol-forbindelser til anvendelse som mellemprodukter ved deres fremstilling
DK184588D0 (da) Mellemprodukter til brug ved fremstilling af 1alfa,25-dihydroxylerede vitamin d2-derivater
DK165984C (da) Fremgangsmaade til fremstilling af sphingosinderivater
DK177489D0 (da) Cholestadienderivater som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater
DK214585D0 (da) Fremgangsmaade til fremstilling af imidazorifamyciner
NO851758L (no) Fremgangsmaate ved fremstilling av isokinolinderivater
DK56490D0 (da) Homocholestenderivater som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater
NO851638L (no) Fremgangsmaate ved fremstilling av iminothiazolidin-derivater
DK437287D0 (da) 2,3-dihydrofuranderivater, deres fremstilling og deres anvendelse som mellemprodukter til fremstilling af tetrahydrofuranderivater
DK559786D0 (da) Mellemprodukter til fremstilling af beta-lactamantibiotika
DK422382A (da) Oxiraner til anvendelse som mellemprodukter ved fremstilling af substituerede 2-hydroxy-3-azolyl-propanderivater
DK422582A (da) Oxiraner til anvendelse som mellemprodukter ved fremstilling af substituerede 1-azolyl-2-hydroxy-alkanderivater
DK145685D0 (da) Fremgangsmaade til fremstilling af 4-acetylimidazolderivater samt mellemprodukter til brug ved fremgangsmaaden
NO166081C (no) Mellomprodukter til bruk ved fremstilling av imidazokinolinderivater
NO166082C (no) Mellomprodukter til bruk ved fremstilling av imidazokinolinonderivater.
DK291785A (da) Fremgangsmaade til fremstilling af iminderivater
DK321484D0 (da) Steffimycinon-analoge og deres fremstilling, mellemprodukter til anvendelse ved fremstillingen samt anvendelse af de steffimycinon-analoge som antibakterielle midler og til syntese af antitumormidler
DK564985D0 (da) Fremgangsmaade til fremstilling af alkylthioacetamidiner
DK87285A (da) Fremgangsmaade til fremstilling af 3-methyl-7-fluor-5-nitrobenzothiophen samt ved fremstillingen benyttes mellemprodukter
NO168472C (no) Substituerte cyanomethylbenzamidforbindelser egnet for anvendelse som mellomprodukter ved fremstilling av terapeutisk virksomme benzamidforbindelser
DK64085A (da) Fremgangsmaade til fremstilling af imidazolderivater
NO905385D0 (no) Tiazolderivater egnet som mellomprodukter ved fremstilling av terapeutisk aktive monosulfaktamer.
DK144698C (da) 2,4-diamino-6-halogen-5-benzylpyrimidiner til anvendelse som mellemprodukter ved fremstilling af 2,4-diamino-5-benzylpyrimidiner