DK1506222T3 - Kimæriske, humane papillomavirus16 L1-proteiner omfattende et L2-peptid, viruslignende partikler fremstillet deraf samt en fremgangsmåde til at fremstille partiklerne - Google Patents

Kimæriske, humane papillomavirus16 L1-proteiner omfattende et L2-peptid, viruslignende partikler fremstillet deraf samt en fremgangsmåde til at fremstille partiklerne

Info

Publication number: DK1506222T3
Authority: DK; Denmark
Prior art keywords: peptide; particles; dna sequence; polypeptide; producing
Prior art date: 2002-05-17

Application number

DK03727750T

Other languages

English (en)

Inventor

Arvind Devshi Varsani

Edward Peter Rybicki

Original Assignee

Univ Cape Town

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-17

Filing date

2003-05-19

Publication date

2009-07-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29550639&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1506222(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-05-19 Application filed by Univ Cape Town filed Critical Univ Cape Town

2009-07-06 Application granted granted Critical

2009-07-06 Publication of DK1506222T3 publication Critical patent/DK1506222T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Biotechnology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK03727750T 2002-05-17 2003-05-19 Kimæriske, humane papillomavirus16 L1-proteiner omfattende et L2-peptid, viruslignende partikler fremstillet deraf samt en fremgangsmåde til at fremstille partiklerne DK1506222T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ZA200203957		2002-05-17
PCT/IB2003/001912 WO2003097673A2 (en)	2002-05-17	2003-05-19	Chimeric human papillomavirus 16 l1 proteins comprising an l2 peptide,virus-like particles prepared therefrom and a method for preparing the particles.

Publications (1)

Publication Number	Publication Date
DK1506222T3 true DK1506222T3 (da)	2009-07-06

Family

ID=29550639

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03727750T DK1506222T3 (da)	2002-05-17	2003-05-19	Kimæriske, humane papillomavirus16 L1-proteiner omfattende et L2-peptid, viruslignende partikler fremstillet deraf samt en fremgangsmåde til at fremstille partiklerne

Country Status (13)

Country	Link
US (2)	US7407807B2 (da)
EP (1)	EP1506222B2 (da)
JP (2)	JP4614765B2 (da)
AT (1)	ATE424409T1 (da)
AU (1)	AU2003232951B2 (da)
CA (1)	CA2486450C (da)
CY (1)	CY1109257T1 (da)
DE (1)	DE60326449D1 (da)
DK (1)	DK1506222T3 (da)
ES (1)	ES2323634T5 (da)
PT (1)	PT1506222E (da)
SI (1)	SI1506222T1 (da)
WO (1)	WO2003097673A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0228715D0 (en) *	2002-12-09	2003-01-15	Glaxosmithkline Biolog Sa	Vaccine
PL2374892T3 (pl)	2005-04-29	2018-06-29	University Of Cape Town	Ekspresja białek wirusa w roślinach
ES2310062B1 (es)	2005-07-15	2009-11-13	Bionostra, S.L.	Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones.
CN1328287C (zh) *	2005-12-29	2007-07-25	西安交通大学	Hpv16 l1蛋白模拟肽及其用于制备hpv16诊断试剂和疫苗的用途
CA2703066A1 (en) *	2007-10-22	2009-04-30	University Of Rochester	Respiratory syncytial virus vaccine based on chimeric papillomavirus virus-like particles or capsomeres
BRPI1014718A2 (pt) *	2009-06-25	2016-04-12	Glaxonsmithkline Biolog S A	polipeptídeo do papiloma vírus humano, capsômero, partícula tipo vírus, composição imunogência, molécula de ácido nucléico, e, métodos para produzir o polipeptídeo, e, para preparar uma composição imunogênica
US20120225090A1 (en) *	2009-08-03	2012-09-06	The Johns Hopkins University	Methods for enhancing antigen-specific immune responses
AU2011258501B2 (en)	2010-05-25	2016-07-07	Qiagen Gaithersburg, Inc.	Fast results hybrid capture assay and associated strategically-truncated probes
MY184076A (en) *	2011-12-01	2021-03-17	Univ Cape Town	Hpv chimaeric particle
WO2015009853A1 (en) *	2013-07-16	2015-01-22	University Of Louisville Research Foundation, Inc.	Compositions for mucusal delivery, useful for treating papillomavirus infections
JP7017811B2 (ja) *	2020-02-13	2022-02-09	国立研究開発法人農業・食品産業技術総合研究機構	ウイルス様粒子及びその使用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5618536A (en) *	1992-09-03	1997-04-08	The United States Of America As Represented By The Department Of Health And Human Services	Chimeric papillomavirus-like particles
US6066324A (en) *	1994-10-07	2000-05-23	Loyola University Of Chicago	Carboxyl terminal of papilloma virus L1 region is not required for formation of virus-like particles
GB9621091D0 (en) *	1996-10-09	1996-11-27	Fondation Pour Le Perfectionem	Attenuated microorganisms strains and their uses
US6228368B1 (en) †	1997-10-06	2001-05-08	Loyola University Of Chicago	Papilloma virus capsomere formulations and method of use
US6926897B1 (en) †	1998-03-24	2005-08-09	Medigene Aktiengesellschaft	Medicament for the avoidance or treatment of papillomavirus-specific tumour
DE19812941A1 (de) †	1998-03-24	1999-10-07	Medigene Ag	Arzneimittel zur Vermeidung oder Behandlung von Papillomavirusspezifischem Tumor
JP4563582B2 (ja)	1998-08-14	2010-10-13	メルク・シャープ・エンド・ドーム・コーポレイション	ヒトパピローマウイルスのウイルス様粒子を使用するタンパク質送達系
GB9921146D0 (en) †	1999-09-07	1999-11-10	Smithkline Beecham Biolog	Novel composition
CN107080833A (zh) †	2009-04-10	2017-08-22	约翰·霍普金斯大学	作为广谱人类乳头状瘤病毒（hpv）疫苗的乳头状瘤病毒样颗粒（vlp）

2003
- 2003-05-19 DK DK03727750T patent/DK1506222T3/da active
- 2003-05-19 EP EP03727750A patent/EP1506222B2/en not_active Expired - Lifetime
- 2003-05-19 JP JP2004506346A patent/JP4614765B2/ja not_active Expired - Fee Related
- 2003-05-19 PT PT03727750T patent/PT1506222E/pt unknown
- 2003-05-19 AT AT03727750T patent/ATE424409T1/de active
- 2003-05-19 US US10/514,878 patent/US7407807B2/en not_active Expired - Fee Related
- 2003-05-19 DE DE60326449T patent/DE60326449D1/de not_active Expired - Lifetime
- 2003-05-19 WO PCT/IB2003/001912 patent/WO2003097673A2/en active Application Filing
- 2003-05-19 CA CA2486450A patent/CA2486450C/en not_active Expired - Fee Related
- 2003-05-19 AU AU2003232951A patent/AU2003232951B2/en not_active Ceased
- 2003-05-19 ES ES03727750T patent/ES2323634T5/es not_active Expired - Lifetime
- 2003-05-19 SI SI200331600T patent/SI1506222T1/sl unknown
2008
- 2008-07-16 US US12/174,104 patent/US8163557B2/en not_active Expired - Lifetime
2009
- 2009-06-04 CY CY20091100595T patent/CY1109257T1/el unknown
2010
- 2010-06-16 JP JP2010137490A patent/JP2010263899A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
EP1506222B2 (en)	2012-05-23
WO2003097673A2 (en)	2003-11-27
JP2010263899A (ja)	2010-11-25
WO2003097673A3 (en)	2004-03-18
CA2486450A1 (en)	2003-11-27
EP1506222B1 (en)	2009-03-04
SI1506222T1 (sl)	2009-10-31
ES2323634T3 (es)	2009-07-22
ES2323634T5 (es)	2012-09-04
US8163557B2 (en)	2012-04-24
US20060035319A1 (en)	2006-02-16
JP2006507797A (ja)	2006-03-09
AU2003232951B2 (en)	2009-07-23
PT1506222E (pt)	2009-06-12
EP1506222A2 (en)	2005-02-16
JP4614765B2 (ja)	2011-01-19
US7407807B2 (en)	2008-08-05
ATE424409T1 (de)	2009-03-15
DE60326449D1 (de)	2009-04-16
CA2486450C (en)	2013-11-19
WO2003097673B1 (en)	2004-04-22
AU2003232951A1 (en)	2003-12-02
US20090047302A1 (en)	2009-02-19
CY1109257T1 (el)	2014-07-02

Publication	Publication Date	Title
CY1109257T1 (el)	2014-07-02	Χιμαιρικες πρωτεϊνες l1 του ιου 16 ανθρωπινων θηλωματων που περιλαμβανουν l2 πεπτιδιο, ομοιαζοντα με ιο σωματιδια που παρασκευαζονται απο αυτες και μεθοδος παρασκευης των σωματιδιων
WO2004044176A3 (en)	2004-08-26	Adenoviral vector vaccine
BR0113307A (pt)	2005-06-28	Molécula de proteìna quimérica de núcleo de vìrus de hepatite b recombinante, partìcula imunogênica, vacina ou inóculo, ácido nucleico, molécula de ácido nucleico recombinante, célula hospedeira e método de induzir uma resposta imunológica em um animal hospedeiro inoculado
SG153874A1 (en)	2009-07-29	Neutralizing epitope-based growth enhancing vaccine
MXPA05010007A (es)	2006-03-10	Replicones de alfavirus y construcciones auxiliares mejorados.
MXPA03009354A (es)	2004-03-02	Un clon infeccioso de adnc del virus del sindrome reproductivo y respiratorio porcino (prrs) norteamericano y sus usos.
FR11C0022I1 (da)	2011-05-08
ATE374828T1 (de)	2007-10-15	Expressionsvektor zur antibiotikafreien expression
MY140664A (en)	2010-01-15	Optimized expression of hpv 45 l1 in yeast
MXPA05008677A (es)	2006-02-22	Particulas quimericas de hbc estabilizadas como vacuna terapeutica para hepatitis cronica.
ES2170622A1 (es)	2002-08-01	Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
WO2002081709A3 (en)	2003-03-06	Modified hpv e6 and e7 genes and proteins useful for vaccination
DK1246917T3 (da)	2009-06-08	Humane Stra6-polypeptider
GB0608368D0 (en)	2006-06-07	Process for making Oligopeptides
ATE290399T1 (de)	2005-03-15	Hbv/hcv virus-ohnliche particle
CN1369014A (zh)	2002-09-11	蛋白质生产
DE60119535D1 (de)	2006-06-14	Herstellung eines rekombinanten proteins in prokaryotischen wirtszellen durch kodonsoptimisierung
WO2002044323A3 (en)	2002-10-10	Vectors for expressing heterologous peptides at the amino-terminus of potyvirus coat protein, methods for use thereof, plants infected with same and methods of vaccination using same
AUPQ661600A0 (en)	2000-05-04	A nucleic acid construct and methods related thereto
ATE547427T1 (de)	2012-03-15	Verfahren zur rekombinanten herstellung von ribonukleoproteinen
ATE380863T1 (de)	2007-12-15	Neue, aus bacillus licheniformis stammende aminopeptidase, die aminopeptidase codierendes gen, das gen enthaltender expressionsvektor, transformant sowie verfahren zur herstellung davon
SE0002498D0 (sv)	2000-07-03	Papillomavirus vaccine
EP1535628A3 (en)	2008-01-23	HBV/HCV virus-like particle