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DK1456670T3 - Fremgangsmåde relateret til behandling af atherosklerose - Google Patents

Fremgangsmåde relateret til behandling af atherosklerose

Info

Publication number
DK1456670T3
DK1456670T3 DK02758547T DK02758547T DK1456670T3 DK 1456670 T3 DK1456670 T3 DK 1456670T3 DK 02758547 T DK02758547 T DK 02758547T DK 02758547 T DK02758547 T DK 02758547T DK 1456670 T3 DK1456670 T3 DK 1456670T3
Authority
DK
Denmark
Prior art keywords
treatment
atherosclerosis
procedure related
atherosclerotic disorders
lipid
Prior art date
Application number
DK02758547T
Other languages
English (en)
Inventor
Ivan Petyaev
Original Assignee
Cambridge Theranostics Ltd
Petyaev Ivan Mikhailovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0120428A external-priority patent/GB0120428D0/en
Priority claimed from GB0202774A external-priority patent/GB0202774D0/en
Priority claimed from GB0204611A external-priority patent/GB0204611D0/en
Priority claimed from GB0216530A external-priority patent/GB0216530D0/en
Priority claimed from GB0216755A external-priority patent/GB0216755D0/en
Application filed by Cambridge Theranostics Ltd, Petyaev Ivan Mikhailovich filed Critical Cambridge Theranostics Ltd
Application granted granted Critical
Publication of DK1456670T3 publication Critical patent/DK1456670T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56927Chlamydia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
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    • A61K31/13Amines
    • A61K31/132Amines having two or more amino groups, e.g. spermidine, putrescine
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    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/409Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002Antibodies with enzymatic activity, e.g. abzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/323Arteriosclerosis, Stenosis

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DK02758547T 2001-08-22 2002-08-22 Fremgangsmåde relateret til behandling af atherosklerose DK1456670T3 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB0120428A GB0120428D0 (en) 2001-08-22 2001-08-22 Method of analysis
US32312701P 2001-09-18 2001-09-18
US35565502P 2002-02-06 2002-02-06
GB0202774A GB0202774D0 (en) 2002-02-06 2002-02-06 Methods and means
GB0204611A GB0204611D0 (en) 2002-02-27 2002-02-27 Methods of measurement
GB0216530A GB0216530D0 (en) 2002-07-16 2002-07-16 Methods and means
GB0216755A GB0216755D0 (en) 2002-07-18 2002-07-18 Methods and means
PCT/GB2002/003863 WO2003019198A2 (en) 2001-08-22 2002-08-22 Methods relating to treatment of atherosclerosis

Publications (1)

Publication Number Publication Date
DK1456670T3 true DK1456670T3 (da) 2009-11-16

Family

ID=27562595

Family Applications (2)

Application Number Title Priority Date Filing Date
DK02758547T DK1456670T3 (da) 2001-08-22 2002-08-22 Fremgangsmåde relateret til behandling af atherosklerose
DK02755229T DK1454140T3 (da) 2001-08-22 2002-08-22 Diagnose og behandling af atherosklerose

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK02755229T DK1454140T3 (da) 2001-08-22 2002-08-22 Diagnose og behandling af atherosklerose

Country Status (9)

Country Link
EP (3) EP1454140B1 (da)
JP (2) JP4374248B2 (da)
AT (1) ATE436020T1 (da)
AU (1) AU2002321526A1 (da)
DE (2) DE60232913D1 (da)
DK (2) DK1456670T3 (da)
EA (1) EA009661B1 (da)
ES (2) ES2329770T3 (da)
WO (3) WO2003019198A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005023368A1 (en) * 2003-09-04 2005-03-17 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Prophylaxis of and treatment for infections from the family chlamydiaceae using amino acids as leucine or methionine
WO2005027961A2 (en) * 2003-09-23 2005-03-31 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Chlamydia pmpd autotransporter and its role as adhesin
GB0323348D0 (en) * 2003-10-06 2003-11-05 Cambridge Theranostics Ltd Methods and means for modulating lipid metabolism
GB0503940D0 (en) * 2005-02-25 2005-04-06 Cambridge Theranostics Ltd Assay methods
GB0503939D0 (en) 2005-02-25 2005-04-06 Cambridge Theranostics Ltd Chlamydia detection
WO2006104402A1 (en) * 2005-03-26 2006-10-05 Protemix Corporation Limited Copper antagonist compositions
GB0515035D0 (en) * 2005-07-21 2005-08-31 Cambridge Theranostics Ltd Treatment of atherosclerotic conditions
JP2009512426A (ja) * 2005-10-14 2009-03-26 イヴァン・ペテャエフ 偏性細胞内病原体の治療および診断
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EP1454140A2 (en) 2004-09-08
ES2328907T3 (es) 2009-11-19
EP1456670A2 (en) 2004-09-15
JP2005501258A (ja) 2005-01-13
JP4307999B2 (ja) 2009-08-05
EA200400338A1 (ru) 2004-12-30
EP1456670B8 (en) 2011-04-27
JP4374248B2 (ja) 2009-12-02
WO2003019198A3 (en) 2004-03-04
EP1456670B1 (en) 2009-07-15
DK1454140T3 (da) 2009-11-16
JP2005502665A (ja) 2005-01-27
EA009661B1 (ru) 2008-02-28
WO2003017992A2 (en) 2003-03-06
DE60232992D1 (de) 2009-08-27
ES2329770T3 (es) 2009-12-01
WO2003019196A3 (en) 2004-03-04
ATE436020T1 (de) 2009-07-15
DE60232913D1 (de) 2009-08-20
WO2003019198A2 (en) 2003-03-06
WO2003019196A2 (en) 2003-03-06
EP1456402A2 (en) 2004-09-15
WO2003017992A3 (en) 2004-06-17
EP1454140B1 (en) 2009-07-08

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