DK0817851T3 - DNA, der koder for humant papillomvirus type 18 - Google Patents

DNA, der koder for humant papillomvirus type 18

Info

Publication number: DK0817851T3
Authority: DK; Denmark
Prior art keywords: dna encoding; encoding human; human papillomavirus; papillomavirus type; type
Prior art date: 1995-03-22

Application number

DK96909743T

Other languages

English (en)

Other versions

DK0817851T5 (da

Inventor

Kathryn J Hofmann

Kathrin U Jansen

Michael P Neeper

Joseph G Joyce

Hugh A George

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-22

Filing date

1996-03-18

Publication date

2004-08-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27020342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0817851(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-03-22 Priority claimed from US08/409,122 external-priority patent/US5820870A/en

1995-03-22 Priority claimed from US08/408,669 external-priority patent/US5840306A/en

1996-03-18 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2004-08-16 Application granted granted Critical

2004-08-16 Publication of DK0817851T3 publication Critical patent/DK0817851T3/da

2004-10-25 Publication of DK0817851T5 publication Critical patent/DK0817851T5/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/905—Stable introduction of foreign DNA into chromosome using homologous recombination in yeast
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
- C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Virology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Mycology (AREA)
Microbiology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Immunology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK96909743T 1995-03-22 1996-03-18 DNA, der koder for humant papillomvirus type 18 DK0817851T5 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/409,122 US5820870A (en)	1995-03-22	1995-03-22	Recombinant human papillomavirus type 18 vaccine
US08/408,669 US5840306A (en)	1995-03-22	1995-03-22	DNA encoding human papillomavirus type 18

Publications (2)

Publication Number	Publication Date
DK0817851T3 true DK0817851T3 (da)	2004-08-16
DK0817851T5 DK0817851T5 (da)	2004-10-25

Family

ID=27020342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96909743T DK0817851T5 (da)	1995-03-22	1996-03-18	DNA, der koder for humant papillomvirus type 18

Country Status (22)

Country	Link
EP (2)	EP0817851B9 (da)
JP (1)	JPH11502704A (da)
KR (1)	KR100430698B1 (da)
CN (1)	CN1100876C (da)
AT (1)	ATE259879T1 (da)
AU (1)	AU714533B2 (da)
CA (1)	CA2215834C (da)
CZ (1)	CZ291242B6 (da)
DE (4)	DE122007000030I1 (da)
DK (1)	DK0817851T5 (da)
EA (1)	EA001092B1 (da)
ES (1)	ES2213772T3 (da)
FR (1)	FR07C0023I2 (da)
HU (1)	HU223761B1 (da)
IL (1)	IL117459A (da)
NL (3)	NL300272I1 (da)
NO (1)	NO322254B1 (da)
NZ (1)	NZ305188A (da)
PL (1)	PL184022B1 (da)
PT (1)	PT817851E (da)
SK (1)	SK284281B6 (da)
WO (1)	WO1996029413A2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9621091D0 (en)	1996-10-09	1996-11-27	Fondation Pour Le Perfectionem	Attenuated microorganisms strains and their uses
ZA982950B (en)	1997-04-08	1998-10-19	Merck & Co Inc	Stabilized human papillomavirus formulations
JP4598201B2 (ja) *	1997-04-08	2010-12-15	メルク・シャープ・エンド・ドーム・コーポレイション	安定化ヒトパピローマウイルス製剤
US6602697B1 (en) *	1998-08-14	2003-08-05	Merck & Co., Inc.	Process for purifying human papillomavirus virus-like particles
AUPP765398A0 (en)	1998-12-11	1999-01-14	University Of Queensland, The	Treatment of papillomavirus infections
ATE413188T1 (de)	1999-02-05	2008-11-15	Merck & Co Inc	Menschliche papillomavirus impfstoff- formulierungen
FR2795074A1 (fr) *	1999-05-21	2000-12-22	Inst Nat Sante Rech Med	Polypeptides transporteurs d'acides amines, et en particulier du glutamate, et procedes de criblage de composes inhibiteurs ou activateurs de l'activite de transport
MY140664A (en) *	2003-09-29	2010-01-15	Merck Sharp & Dohme	Optimized expression of hpv 45 l1 in yeast
TWI457133B (zh)	2005-12-13	2014-10-21	Glaxosmithkline Biolog Sa	新穎組合物
US9428555B2 (en)	2007-04-29	2016-08-30	Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.	Truncated L1 protein of Human Papillomavirus type 16
CN101570571B (zh) *	2007-04-29	2012-07-11	北京万泰生物药业股份有限公司	截短的人乳头瘤病毒18型l1蛋白
CN101440373B (zh) *	2007-11-23	2012-09-05	上海泽润生物科技有限公司	一种截短型的18型人乳头状瘤病毒主要衣壳蛋白l1基因
BRPI1014718A2 (pt) *	2009-06-25	2016-04-12	Glaxonsmithkline Biolog S A	polipeptídeo do papiloma vírus humano, capsômero, partícula tipo vírus, composição imunogência, molécula de ácido nucléico, e, métodos para produzir o polipeptídeo, e, para preparar uma composição imunogênica
MX348241B (es) *	2011-06-15	2017-06-01	Hong Jin Kim	Metodo para mejorar el rendimiento de produccion de la proteina l1 del virus del papiloma humano.
BR112014023092A8 (pt)	2012-03-18	2017-07-25	Glaxosmithkline Biologicals Sa	Composição imunogênica, método para a prevenção de infecção ou doença por hpv em um indivíduo, e, kit
CN108276491B (zh) *	2018-02-05	2021-01-12	南京薇熙生物医药科技有限公司	一种可特异性识别hpv18 l1蛋白的单克隆抗体及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3625257A1 (de) *	1986-07-23	1988-02-04	Behringwerke Ag	Expressionsprodukte der menschlichen papillomviren typ 16 und 18, fuer diese proteine spezifische antikoerper und diese antikoerper bzw. entsprechende dna enthaltende diagnostika
DE4015044A1 (de) *	1990-05-10	1991-11-14	Behringwerke Ag	Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18
DE122007000023I1 (de) *	1991-07-19	2007-08-09	Univ Queensland St Lucia	Impfsstoff gegen Humanes Papillomavirus (typ 18)
DE122007000099I1 (de) *	1992-06-25	2008-03-27		Papillomavirus vakzine
US5437951A (en) *	1992-09-03	1995-08-01	The United States Of America As Represented By The Department Of Health And Human Services	Self-assembling recombinant papillomavirus capsid proteins
PT1618888E (pt) *	1993-03-09	2011-04-08	Univ Rochester	Produção de proteína da cápside de vírus de papiloma humano e partículas semelhantes a vírus

1996
- 1996-03-13 IL IL11745996A patent/IL117459A/xx active Protection Beyond IP Right Term
- 1996-03-18 HU HU9801334A patent/HU223761B1/hu active IP Right Grant
- 1996-03-18 WO PCT/US1996/003649 patent/WO1996029413A2/en active IP Right Grant
- 1996-03-18 SK SK1278-97A patent/SK284281B6/sk not_active IP Right Cessation
- 1996-03-18 CN CN96194121A patent/CN1100876C/zh not_active Expired - Lifetime
- 1996-03-18 JP JP8528535A patent/JPH11502704A/ja active Pending
- 1996-03-18 DE DE200712000030 patent/DE122007000030I1/de active Pending
- 1996-03-18 KR KR1019970706580A patent/KR100430698B1/ko not_active IP Right Cessation
- 1996-03-18 NZ NZ305188A patent/NZ305188A/xx not_active IP Right Cessation
- 1996-03-18 PL PL96322333A patent/PL184022B1/pl unknown
- 1996-03-18 AT AT96909743T patent/ATE259879T1/de active
- 1996-03-18 ES ES96909743T patent/ES2213772T3/es not_active Expired - Lifetime
- 1996-03-18 DK DK96909743T patent/DK0817851T5/da active
- 1996-03-18 EP EP96909743A patent/EP0817851B9/en not_active Expired - Lifetime
- 1996-03-18 CA CA002215834A patent/CA2215834C/en not_active Expired - Lifetime
- 1996-03-18 DE DE69631586T patent/DE69631586T9/de active Active
- 1996-03-18 DE DE200712000031 patent/DE122007000031I1/de active Pending
- 1996-03-18 CZ CZ19972936A patent/CZ291242B6/cs not_active IP Right Cessation
- 1996-03-18 PT PT96909743T patent/PT817851E/pt unknown
- 1996-03-18 EP EP04075256A patent/EP1422294A1/en not_active Withdrawn
- 1996-03-18 EA EA199700256A patent/EA001092B1/ru not_active IP Right Cessation
- 1996-03-18 DE DE1996631586 patent/DE122007000025I1/de active Pending
- 1996-03-18 AU AU53141/96A patent/AU714533B2/en not_active Expired
1997
- 1997-09-19 NO NO19974322A patent/NO322254B1/no not_active IP Right Cessation
2007
- 2007-03-14 NL NL300272C patent/NL300272I1/nl unknown
- 2007-03-14 NL NL300273C patent/NL300273I1/nl unknown
- 2007-03-14 NL NL300271C patent/NL300271I1/nl unknown
- 2007-03-20 FR FR07C0023C patent/FR07C0023I2/fr active Active

Also Published As

Publication number	Publication date
NL300272I1 (nl)	2007-05-01
HUP9801334A2 (hu)	1998-08-28
DE69631586T9 (de)	2005-06-16
FR07C0023I1 (da)	2007-04-27
EP0817851B9 (en)	2004-08-18
HUP9801334A3 (en)	1999-04-28
NO974322L (no)	1997-11-24
NO974322D0 (no)	1997-09-19
MX9707208A (es)	1997-11-29
CA2215834C (en)	2007-06-12
NL300273I1 (nl)	2007-05-01
PL322333A1 (en)	1998-01-19
EP0817851B1 (en)	2004-02-18
DE122007000031I1 (de)	2007-07-19
WO1996029413A3 (en)	1996-11-28
NO322254B1 (no)	2006-09-04
EA199700256A1 (ru)	1999-06-24
CA2215834A1 (en)	1996-09-26
DE122007000025I1 (de)	2007-07-12
DE69631586D1 (de)	2004-03-25
SK127897A3 (en)	1998-07-08
ES2213772T3 (es)	2004-09-01
DK0817851T5 (da)	2004-10-25
PT817851E (pt)	2004-06-30
CZ293697A3 (cs)	1998-02-18
EA001092B1 (ru)	2000-10-30
IL117459A (en)	2005-11-20
DE69631586T2 (de)	2005-01-27
EP0817851A2 (en)	1998-01-14
WO1996029413A2 (en)	1996-09-26
HU223761B1 (hu)	2005-01-28
CN1100876C (zh)	2003-02-05
IL117459A0 (en)	1996-07-23
KR100430698B1 (ko)	2004-07-15
PL184022B1 (pl)	2002-08-30
CZ291242B6 (cs)	2003-01-15
CN1185176A (zh)	1998-06-17
AU714533B2 (en)	2000-01-06
NL300271I1 (nl)	2007-05-01
NZ305188A (en)	1999-11-29
FR07C0023I2 (fr)	2012-08-03
ATE259879T1 (de)	2004-03-15
JPH11502704A (ja)	1999-03-09
SK284281B6 (sk)	2004-12-01
AU5314196A (en)	1996-10-08
DE122007000030I1 (de)	2007-07-19
EP1422294A1 (en)	2004-05-26

Publication	Publication Date	Title
NL300273I1 (nl)	2007-05-01	DNA dat humaan papillomavirus type 18 codeert.
BG100974A (en)	1998-04-30	Vaccines against papillomavirus
NL300135I2 (nl)	2004-05-03	Prostaglandinen van de F-reeks.
ATE241014T2 (de)	2003-06-15	Hiv-2 varianten
NO971875L (no)	1997-06-12	Cathepsin 02 protease
EA199700281A1 (ru)	1998-04-30	Молекула днк, кодирующая белок l1 вируса папилломы типа 11 чепловека, экспрессирующий вектор, способ получения очищенных вирусоподобных частиц
ATE212055T1 (de)	2002-02-15	Östrogen-rezeptor
NO965084D0 (no)	1996-11-28	N-[3(3-cyanopyrazol[1,5-aÅpyrimidin-7-yl)fenylÅ-N-etyl-acetamid
MA23778A1 (fr)	1996-10-01	Purine-6-ones-2,9 disubstituees
DE3870959D1 (de)	1992-06-17	2-difluormethoxy-1,1,1,2-tetrafluoraethan als anaesthetikum.
DK0990703T3 (da)	2008-09-29	Nyt polypeptid, DNA, som koder herfor, samt anvendelse heraf
SE9602822D0 (sv)	1996-07-19	New receptor
PE20399A1 (es)	1999-03-05	Muteina ob
TR199501263A2 (tr)	1996-06-21	Agiz yoluyla alinan sabeluzol süspansiyonlari.
ES2073495T3 (es)	1995-08-16	Benzotiazepinas.
ATE68486T1 (de)	1991-11-15	1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl - 1h-imidazol.
SE9604439D0 (sv)	1996-12-02	New receptor
ES2191785T3 (es)	2003-09-16	Proteina de accion antitumoral.
AU2859892A (en)	1993-06-03	Aminoalkyl-substituted 5,6-dihydro-dibenz(b,e)azepine-6,11-dione-11-oximes
IT8719319A0 (it)	1987-02-10	Catena per pneumatici nonche'procedimento per la sua fabbricazione.
TR199801087T2 (xx)	1998-09-21	4,10 �- diasetoksi-2alfa-Benzoiloksi- 5 �, 20 epoksi-1- hidroksi-9- okso-19- norsiklopropa(G) taks-11- en- 13alfa-il
KR950024792U (ko)	1995-09-15	차량용 엘. 피. 지 캡(l. p. g cap)
MX9203129A (es)	1992-07-01	Proteinas bmp-5.
ITRM940330A0 (it)	1994-05-26	"procedimento migliorato per la preparazione della 14b-idrossi-etianaldeide".