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DK0701815T3 - Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr - Google Patents

Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr

Info

Publication number
DK0701815T3
DK0701815T3 DK95113398T DK95113398T DK0701815T3 DK 0701815 T3 DK0701815 T3 DK 0701815T3 DK 95113398 T DK95113398 T DK 95113398T DK 95113398 T DK95113398 T DK 95113398T DK 0701815 T3 DK0701815 T3 DK 0701815T3
Authority
DK
Denmark
Prior art keywords
hydrophilic
macar
pellets
granules
preparation
Prior art date
Application number
DK95113398T
Other languages
English (en)
Inventor
Ursula Schick
Juergen Werry
Juergen Freidenreich
Jens-Christian Wunderlich
Original Assignee
Alfatec Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27435369&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0701815(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4201179A external-priority patent/DE4201179A1/de
Priority claimed from DE4201173A external-priority patent/DE4201173C2/de
Application filed by Alfatec Pharma Gmbh filed Critical Alfatec Pharma Gmbh
Application granted granted Critical
Publication of DK0701815T3 publication Critical patent/DK0701815T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216Solid or semisolid forms
    • A61K8/022Powders; Compacted Powders
    • A61K8/0225Granulated powders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Glanulating (AREA)
DK95113398T 1992-01-17 1993-01-18 Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr DK0701815T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4201179A DE4201179A1 (de) 1992-01-17 1992-01-17 Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
DE4201173A DE4201173C2 (de) 1992-01-17 1992-01-17 Akutarzneimittel in Form von Dihydropyridinderivaten enthaltenden Pellets und ihre Herstellung
US07/876,864 US5405616A (en) 1992-01-17 1992-04-30 Means for containing active substances, having a shell of hydrophilic macromolecules, active substances and process for preparation thereof
US07/876,877 US5384129A (en) 1992-01-17 1992-04-30 Pellets containing dihydropyridine derivatives process for the production thereof and use as rapid action dosage in heart and circulatory diseases

Publications (1)

Publication Number Publication Date
DK0701815T3 true DK0701815T3 (da) 2000-02-07

Family

ID=27435369

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93902034.3T DK0621777T3 (da) 1992-01-17 1993-01-18 Pellets indeholdende aktivt stof og med en matrix af hydrofile makromolekyler, og fremgangsmåde til deres fremstilling
DK95113398T DK0701815T3 (da) 1992-01-17 1993-01-18 Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK93902034.3T DK0621777T3 (da) 1992-01-17 1993-01-18 Pellets indeholdende aktivt stof og med en matrix af hydrofile makromolekyler, og fremgangsmåde til deres fremstilling

Country Status (10)

Country Link
EP (2) EP0701815B1 (da)
JP (1) JPH07502736A (da)
AT (2) ATE181666T1 (da)
AU (1) AU679906B2 (da)
CA (1) CA2128244C (da)
DE (2) DE59303759C5 (da)
DK (2) DK0621777T3 (da)
ES (2) ES2092808T3 (da)
GR (2) GR3021223T3 (da)
WO (1) WO1993013757A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2714575B1 (fr) * 1994-01-03 1996-02-02 Rhone Poulenc Nutrition Animal Nouveaux granulés contenant des organismes vivant pour l'alimentation animale.
SE9704401D0 (sv) * 1997-11-28 1997-11-28 Astra Ab Matrix pellets for greasy, oily or sticky drug substances
DE50105469D1 (de) * 2001-03-22 2005-04-07 Cognis Iberia Sl Mikrokapseln (VII)
US6835802B2 (en) 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6713452B2 (en) 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828297B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
FR2843302B1 (fr) 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
FR2843301B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
EP1551373B1 (de) * 2002-10-16 2014-11-12 MedSkin Solutions Dr. Suwelack AG Verwendung von formkörpern zur äusseren anwendung
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
UA91512C2 (ru) 2004-07-19 2010-08-10 Биокон Лимитед Коньюгати олигомеров инсулина, их композиция (варианты) и применение
FR2887455B1 (fr) * 2005-06-28 2007-08-10 Sanofi Aventis Sa Formulation a liberation prolongee de principes actifs de medicaments
AU2007295178B2 (en) * 2006-09-15 2013-04-18 Echo Pharmaceuticals B.V. Granulate containing a pharmaceutically active substance and anemulsifier and method for its manufacture
CN101541299B (zh) 2006-09-15 2013-04-17 艾可制药有限公司 供舌下、口含或口服施用的不溶于水的药物活性物质的剂量单位
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
BRPI1001091A2 (pt) 2009-04-22 2011-03-22 Dr Suwelack Skin & Health Care Ag artigo moldado revestido secado por congelamento
WO2014022195A1 (en) * 2012-08-01 2014-02-06 Tavakoli Zahra Free flowing, frozen compositions comprising a therapeutic agent
ITMI20122145A1 (it) * 2012-12-14 2014-06-15 Velleja Res Srl Composizioni per uso orale contenenti idrolizzati di collagene, di elastina e vitamina c favorenti la deposizione di matrice extra-cellulare
LU102656B1 (de) 2021-03-11 2022-09-12 Prosecur Gmbh Flüssiges Nahrungsergänzungsmittel zur Immunstimulation, Verfahren zu dessen Herstellung sowie Verwendung

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1248863B (da) * 1959-01-30
GB887901A (da) * 1960-04-13 1900-01-01
IE53696B1 (en) * 1981-12-02 1989-01-18 Wyeth John & Brother Ltd Solid shaped articles
EP0138216B1 (en) * 1983-10-14 1993-01-07 Sumitomo Pharmaceuticals Company, Limited Sustained-release ifn preparation for parenteral administration
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
FR2634121B1 (fr) * 1988-07-13 1992-05-07 Imedex Procede de preparation de microparticules de collagene et produits obtenus
JPH02135052A (ja) * 1988-11-17 1990-05-23 Taiyo Kagaku Co Ltd 粒状食品の製造方法
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
FR2650502B1 (fr) * 1989-08-07 1994-05-27 Delagrange Laboratoires Nouvelle forme galenique orale ameliorant la biodisponibilite
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
ATE156350T1 (de) 1992-01-17 1997-08-15 Alfatec Pharma Gmbh Peptidarzneistoffe enthaltende pellets und ihre herstellung sowie deren verwendung
ES2102637T3 (es) 1992-01-17 1997-08-01 Alfatec Pharma Gmbh Cuerpos moldeados criogranulados que contienen un extracto de sustancias vegetales activas y su utilizacion farmaceutica o cosmetica.
ATE132036T1 (de) 1992-01-17 1996-01-15 Alfatec Pharma Gmbh Verfahren zur herstellung von weichgelatinekapseln nach einem tropfverfahren
DE4221880A1 (de) * 1992-07-03 1994-01-05 Alfatec Pharma Gmbh Feste und flüssige Lösungen von schwer wasserlöslichen Arzneistoffen

Also Published As

Publication number Publication date
DE59303759D1 (de) 1996-10-17
ES2092808T3 (es) 1996-12-01
AU3343293A (en) 1993-08-03
EP0701815A1 (de) 1996-03-20
JPH07502736A (ja) 1995-03-23
CA2128244C (en) 1998-09-22
EP0701815B1 (de) 1999-06-30
WO1993013757A1 (de) 1993-07-22
ES2133633T3 (es) 1999-09-16
GR3021223T3 (en) 1997-01-31
EP0621777A1 (de) 1994-11-02
EP0621777B1 (de) 1996-09-11
DK0621777T3 (da) 1996-10-21
AU679906B2 (en) 1997-07-17
ATE142484T1 (de) 1996-09-15
DE59309678D1 (de) 1999-08-05
GR3030675T3 (en) 1999-11-30
CA2128244A1 (en) 1993-07-22
DE59303759C5 (de) 2009-04-09
ATE181666T1 (de) 1999-07-15

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