Nothing Special   »   [go: up one dir, main page]

DK0532562T3 - Fremgangsmåde til fremstilling af 10-g(b)-H-steroider - Google Patents

Fremgangsmåde til fremstilling af 10-g(b)-H-steroider

Info

Publication number
DK0532562T3
DK0532562T3 DK91910189.9T DK91910189T DK0532562T3 DK 0532562 T3 DK0532562 T3 DK 0532562T3 DK 91910189 T DK91910189 T DK 91910189T DK 0532562 T3 DK0532562 T3 DK 0532562T3
Authority
DK
Denmark
Prior art keywords
pct
steroids
beta
sec
reduction
Prior art date
Application number
DK91910189.9T
Other languages
English (en)
Inventor
Eckhard Ottow
Guenter Neef
Arwed Cleve
Rudolf Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0532562T3 publication Critical patent/DK0532562T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK91910189.9T 1990-06-01 1991-06-03 Fremgangsmåde til fremstilling af 10-g(b)-H-steroider DK0532562T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4018167A DE4018167A1 (de) 1990-06-01 1990-06-01 Verfahren zur herstellung von 10(beta)-h-steroiden
PCT/EP1991/001018 WO1991018918A1 (de) 1990-06-01 1991-06-03 VERFAHREN ZUR HERSTELLUNG VON 10β-H-STEROIDEN

Publications (1)

Publication Number Publication Date
DK0532562T3 true DK0532562T3 (da) 1995-05-15

Family

ID=6407912

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91910189.9T DK0532562T3 (da) 1990-06-01 1991-06-03 Fremgangsmåde til fremstilling af 10-g(b)-H-steroider

Country Status (12)

Country Link
US (1) US5405979A (da)
EP (1) EP0532562B1 (da)
JP (1) JP2999258B2 (da)
AT (1) ATE114317T1 (da)
CA (1) CA2084313C (da)
DE (2) DE4018167A1 (da)
DK (1) DK0532562T3 (da)
ES (1) ES2065039T3 (da)
FI (1) FI111642B (da)
HU (1) HU218484B (da)
NO (1) NO304115B1 (da)
WO (1) WO1991018918A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4042007A1 (de) * 1990-12-22 1992-06-25 Schering Ag 6,7-modifizierte-11(beta)-aryl-4-estrene
DE19610667C2 (de) * 1996-03-08 1998-04-09 Schering Ag (Z)-11ß-[4-(Dimethylamino)phenyl]17ß-hydroxy-17alpha-(3-hydroxy-1-propenyl)estr-4-en-3-on als kristallines Ansolvat
DE102011004899A1 (de) 2011-03-01 2012-09-06 Bayer Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
US11208432B2 (en) 2015-12-23 2021-12-28 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
WO2017112904A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
US11124537B2 (en) 2015-12-23 2021-09-21 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
MX2019004030A (es) 2016-10-07 2019-09-16 Oric Pharmaceuticals Inc Inhibidores del receptor de glucocorticoides.
TW202010502A (zh) * 2018-04-11 2020-03-16 美商歐瑞克製藥公司 包含糖皮質激素受體拮抗劑之固體形式與調配物及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3014120A1 (de) * 1980-04-12 1981-10-29 Hoechst Ag, 6000 Frankfurt Verfahren zur synthese von oestron bzw. oestronderivaten
AU572589B2 (en) * 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
IE60780B1 (en) * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives

Also Published As

Publication number Publication date
DE59103592D1 (de) 1995-01-12
JPH05507271A (ja) 1993-10-21
FI925445A0 (fi) 1992-11-30
NO304115B1 (no) 1998-10-26
ES2065039T3 (es) 1995-02-01
US5405979A (en) 1995-04-11
NO924617D0 (no) 1992-11-30
WO1991018918A1 (de) 1991-12-12
CA2084313A1 (en) 1991-12-02
HU218484B (hu) 2000-09-28
HU9203775D0 (en) 1993-03-29
EP0532562B1 (de) 1994-11-23
HUT62596A (en) 1993-05-28
CA2084313C (en) 2002-12-10
NO924617L (no) 1992-11-30
JP2999258B2 (ja) 2000-01-17
ATE114317T1 (de) 1994-12-15
FI111642B (fi) 2003-08-29
FI925445A (fi) 1992-11-30
DE4018167A1 (de) 1991-12-05
EP0532562A1 (de) 1993-03-24

Similar Documents

Publication Publication Date Title
JPS559058A (en) 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative
ES2028101T3 (es) Una composicion que comprende un acido carboxilico y una amina.
HU9203557D0 (en) Method for producing sulfonyl compounds
DK0532562T3 (da) Fremgangsmåde til fremstilling af 10-g(b)-H-steroider
ES8609285A1 (es) Procedimiento para preparar derivados de tetrazol con acti- vidad insecticida
DK0565558T3 (da) Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer
JPS5798270A (en) 1,2-disubstituted-4-chloroimidazole-5-acetic acid derivative
JPS5419931A (en) Separation of threo, erythro-3-(3,4-dibenzyloxyphenyl)serines
MY122105A (en) Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids.
HU908020D0 (en) Process for producing benzaldehydes
ES481264A1 (es) Procedimiento para fabricar derivados del acido arilacetico.
MX173831B (es) Compuestos de naftil-azo-pirazolona y procedimiento para la preparacion de los mismos
DK0662952T3 (da) Fremgangsmåde til stereoselektiv syntese af 3-substituerede 2-sulfonylmethylpropionsyrer samt mellemprodukter
JPS5432448A (en) Preparation of cyclopentanone derivative
JPS5212129A (en) Process for preparation of fluorocarbonvinylether
DK0661263T3 (da) Fremgangsmåde til fremstilling af 2,4,5-tribrompyrrol-3-carbonitril
JPS5414952A (en) 1-halogenocarbonyltricyclo(4,3,1,12,5)undecane
JPS5285169A (en) Novel allantoin-n-acetylglutamine-aluminum molecular complex and its p reparation
JPS56118066A (en) 2-cyano-3-halogeno-5-trifluoromethylpyridine and its preparation
IE830147L (en) Hydroxyalkane diphosphonic acid derivatives
JPS5759856A (en) Benzene derivative
JPS52133961A (en) 2-hydroxy-3-methyl-3-(6-methoxy-2-naphthayl)-acrylonitrile and method of preparing the same
JPS5422353A (en) 2-chloro-2-cyano-7-alkylidene-bicyclo(2,2,1)-5-heptene and its preparation
ES8400411A1 (es) Procedimiento para la preparacion de nuevas sulfiminas.
JPS5350156A (en) 3-methyl-3- 4-(1-oxo-2-isoindolinyl)-phenyl pyruvic acid and process forpreparation of the same