DK0512064T3 - Ekstracellulære segmenter af human IgE immuno-globulinforankringspeptider og for disse specifikke antistoffer - Google Patents
Ekstracellulære segmenter af human IgE immuno-globulinforankringspeptider og for disse specifikke antistofferInfo
- Publication number
- DK0512064T3 DK0512064T3 DK91904413.1T DK91904413T DK0512064T3 DK 0512064 T3 DK0512064 T3 DK 0512064T3 DK 91904413 T DK91904413 T DK 91904413T DK 0512064 T3 DK0512064 T3 DK 0512064T3
- Authority
- DK
- Denmark
- Prior art keywords
- ige
- specific antibodies
- membrane
- human ige
- secreted
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 2
- 102000018358 immunoglobulin Human genes 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000012528 membrane Substances 0.000 abstract 3
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 210000003651 basophil Anatomy 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 229940072221 immunoglobulins Drugs 0.000 abstract 1
- 229940051026 immunotoxin Drugs 0.000 abstract 1
- 230000002637 immunotoxin Effects 0.000 abstract 1
- 239000002596 immunotoxin Substances 0.000 abstract 1
- 231100000608 immunotoxin Toxicity 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/468,766 US5260416A (en) | 1987-12-31 | 1990-01-23 | Antigenic epitopes present on membrane-bound but not secreted IgE |
| US07/515,604 US5274075A (en) | 1987-12-31 | 1990-04-27 | Newly identified human epsilon immunoglobulin peptides and related products |
| US63007790A | 1990-12-19 | 1990-12-19 | |
| PCT/US1991/000491 WO1991011456A1 (en) | 1990-01-23 | 1991-01-23 | EXTRACELLULAR SEGMENTS OF HUMAN ε IMMUNOGLOBULIN ANCHORING PEPTIDES AND ANTIBODIES SPECIFIC THEREFOR |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0512064T3 true DK0512064T3 (da) | 1997-12-15 |
Family
ID=27413084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91904413.1T DK0512064T3 (da) | 1990-01-23 | 1991-01-23 | Ekstracellulære segmenter af human IgE immuno-globulinforankringspeptider og for disse specifikke antistoffer |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0512064B1 (da) |
| JP (1) | JP3449712B2 (da) |
| AT (1) | ATE154637T1 (da) |
| AU (2) | AU645783B2 (da) |
| CA (1) | CA2074089C (da) |
| DE (1) | DE69126607T2 (da) |
| DK (1) | DK0512064T3 (da) |
| ES (1) | ES2107454T3 (da) |
| GR (1) | GR3024563T3 (da) |
| HK (1) | HK1002034A1 (da) |
| SG (1) | SG70982A1 (da) |
| WO (1) | WO1991011456A1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6027910A (en) * | 1992-07-08 | 2000-02-22 | Unilever Patent Holdings B.V. | Process for immobilizing enzymes to the cell wall of a microbial cell by producing a fusion protein |
| AU4661293A (en) * | 1993-03-11 | 1994-09-26 | Tanox Biosystems, Inc. | Peptides representing antigenic epitopes of ige present on b cell but not basophil surface |
| US5552537A (en) * | 1993-03-24 | 1996-09-03 | The Regents Of The University Of California | IgE isoforms and methods of use |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| IL116436A (en) | 1995-12-18 | 2006-12-31 | Yissum Res Dev Co | Fc?Á-PE CHIMERIC PROTEIN FOR TARGETED TREATMENT OF ALLERGY RESPONSES AND |
| HUP9901109A3 (en) | 1996-03-01 | 1999-11-29 | Novartis Ag | Peptide immunogens for vaccination against and treatment of allergy |
| US6913749B2 (en) | 1998-11-02 | 2005-07-05 | Resistentia Pharmaceuticals Ab | Immunogenic polypeptides for inducing anti-self IgE responses |
| GB9908533D0 (en) | 1999-04-14 | 1999-06-09 | Novartis Ag | Organic compounds |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7232898B2 (en) | 2002-05-21 | 2007-06-19 | Resistentia Pharmaceuticals Ab | Chimeric IgE polypeptides and host cells |
| JP5740076B2 (ja) | 2005-07-25 | 2015-06-24 | エマージェント・プロダクト・ディベロップメント・シアトル・エルエルシー | Ｃｄ３７特異的及びｃｄ２０特異的結合分子を用いたｂ細胞の減少 |
| JP5389442B2 (ja) * | 2005-09-29 | 2014-01-15 | メディミューン，エルエルシー | 膜Ｉｇ特異的抗体を同定する方法および免疫グロブリンを生成する前駆体細胞を標的化するための使用 |
| JP2009536217A (ja) * | 2006-05-03 | 2009-10-08 | ガスリー ファンデーション フォー エデュケーション アンド リサーチ | Ｂ細胞障害の治療における免疫グロブリン結合細胞表面決定基 |
| NZ612319A (en) | 2006-06-12 | 2015-04-24 | Emergent Product Dev Seattle | Single-chain multivalent binding proteins with effector function |
| AR065368A1 (es) | 2007-02-15 | 2009-06-03 | Astrazeneca Ab | Anticuerpos para moleculas de ige |
| MX2009010092A (es) | 2007-03-22 | 2010-02-09 | Genentech Inc | Anticuerpos anti ige apoptoticos. |
| MX2010011057A (es) | 2008-04-11 | 2010-11-12 | Trubion Pharmaceuticals Inc | Inmunoterapeutico de cd37 y combinacion con quimioterapeutico bifuncional del mismo. |
| US8460664B2 (en) | 2009-02-25 | 2013-06-11 | Academia Sinica | Anti-CεmX antibodies capable of binding to human mIgE on B lymphocytes |
| EP2693887B1 (en) | 2011-04-06 | 2020-10-28 | The Board of Regents of the University of Texas System | Modulating bacterial mam polypeptides in pathogenic disease |
| EP2838919A4 (en) | 2012-04-20 | 2016-03-23 | Academia Sinica | ANTIBLE ANTIBODIES BINDING TO THE TRANSITION BETWEEN CH4 AND C EPSILON MX DOMAINS |
| WO2015013668A1 (en) * | 2013-07-26 | 2015-01-29 | Ke Zhang | Anti-immunoglobulin e antibodies and methods of use thereof |
| TWI603979B (zh) * | 2013-12-05 | 2017-11-01 | 中央研究院 | 抗人類膜錨定型免疫球蛋白a抗體能夠溶解帶有膜錨定型免疫球蛋白a的b淋巴球與降低免疫球蛋白a 的生產 |
| CN108367004B (zh) | 2015-09-21 | 2022-09-13 | 阿帕特夫研究和发展有限公司 | Cd3结合多肽 |
| BR112020008488A2 (pt) | 2017-10-31 | 2020-10-20 | Oneness Biotech Co. Ltd. | tratamento de doenças alérgicas mediadas por ige |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT89107A (pt) * | 1987-11-30 | 1989-11-30 | Idec Pharma Corp | Metodo e meios para a seleccao de anticorpos anti-idiotipos e seu uso para o diagnostico, monitorizacao, tratamento e/ou prevencao de doencas cancerosas, da autoimunidade ou infecciosas |
| AU618317B2 (en) * | 1987-12-31 | 1991-12-19 | Tanox Biosystems, Inc. | Unique antigenic epitopes on ige-bearing b lymphocytes |
-
1991
- 1991-01-23 DK DK91904413.1T patent/DK0512064T3/da active
- 1991-01-23 WO PCT/US1991/000491 patent/WO1991011456A1/en active IP Right Grant
- 1991-01-23 SG SG1996006487A patent/SG70982A1/en unknown
- 1991-01-23 ES ES91904413T patent/ES2107454T3/es not_active Expired - Lifetime
- 1991-01-23 CA CA002074089A patent/CA2074089C/en not_active Expired - Lifetime
- 1991-01-23 AU AU73179/91A patent/AU645783B2/en not_active Expired
- 1991-01-23 EP EP91904413A patent/EP0512064B1/en not_active Expired - Lifetime
- 1991-01-23 DE DE69126607T patent/DE69126607T2/de not_active Expired - Lifetime
- 1991-01-23 JP JP50484591A patent/JP3449712B2/ja not_active Expired - Lifetime
- 1991-01-23 AT AT91904413T patent/ATE154637T1/de not_active IP Right Cessation
-
1993
- 1993-12-03 AU AU52148/93A patent/AU5214893A/en not_active Abandoned
-
1997
- 1997-08-28 GR GR970402202T patent/GR3024563T3/el unknown
-
1998
- 1998-02-12 HK HK98101073A patent/HK1002034A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69126607D1 (de) | 1997-07-24 |
| EP0512064B1 (en) | 1997-06-18 |
| ES2107454T3 (es) | 1997-12-01 |
| WO1991011456A1 (en) | 1991-08-08 |
| JP3449712B2 (ja) | 2003-09-22 |
| AU5214893A (en) | 1994-03-03 |
| CA2074089A1 (en) | 1991-07-24 |
| JPH05504482A (ja) | 1993-07-15 |
| GR3024563T3 (en) | 1997-12-31 |
| HK1002034A1 (en) | 1998-07-24 |
| EP0512064A1 (en) | 1992-11-11 |
| DE69126607T2 (de) | 1998-01-15 |
| AU645783B2 (en) | 1994-01-27 |
| EP0512064A4 (en) | 1993-02-17 |
| ATE154637T1 (de) | 1997-07-15 |
| CA2074089C (en) | 2001-04-10 |
| AU7317991A (en) | 1991-08-21 |
| SG70982A1 (en) | 2000-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0512064T3 (da) | Ekstracellulære segmenter af human IgE immuno-globulinforankringspeptider og for disse specifikke antistoffer | |
| DE59813875D1 (de) | Ko-stimulierendes polypeptid von t-zellen, monoklonale antikörper sowie die herstellung und deren verwendung | |
| KR900702007A (ko) | T세포 항원 수용체의 지어부위와 반응하는 단클론항체 | |
| DE122006000007I2 (de) | -tragenden b-lymphocyten befinden. | |
| DK2067790T3 (da) | Agonistantistof mod proteintyrosinkinase SAL-S1 | |
| ATE95068T1 (de) | Modifizierte antikoerper. | |
| CU22615A1 (es) | Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos | |
| ES2090052T3 (es) | Anticuerpos monoclonales (mak) contra antigenos asociados a tumores, su preparacion y uso. | |
| ATE173740T1 (de) | Antikoerper mit geaenderter zielrichtung | |
| DE3854300D1 (de) | Lymphocyteninhibierung durch hla-peptide. | |
| ES2121358T3 (es) | Anticuerpos monoclonales humanizados contra interleuquina-4 humana. | |
| ID25978A (id) | Antibodi anti-fas | |
| DK0550020T3 (da) | Monoklonale antistoffer mod human-igE | |
| ID20117A (id) | Antibodi anti-fas | |
| DE3884646D1 (de) | Humanes Karcinom-assoziertes Antigen und an dieses Antigen bindende Antikörper. | |
| AU4661293A (en) | Peptides representing antigenic epitopes of ige present on b cell but not basophil surface | |
| NO874107D0 (no) | Nye monoklonale antistoffer mot ifn-omega, fremgangsmaate til fremstilling derav og anvendelse for rensing samt paavisning av ifn-omega. | |
| DE3881275D1 (de) | Monoklonaler antikoerper zur selektiven immunologischen bestimmung von intaktem prokollagen peptid (typ iii) und prokollagen (typ iii) in koerperfluessigkeiten. | |
| DE3775182D1 (de) | Monoklonale antikoerper gegen menschliche ige-rezeptoren auf lymphocyten, diese antikoerper produzierende hybridomas und reaktionsansaetze zum gebrauch dieser antikoerper. | |
| MX9202642A (es) | Anticuerpos monoclonales y antigeno para melanoma humano. | |
| DE69131289D1 (de) | Polypeptide mit einer aktivität des menschlichen dopaminergischen rezeptors, deren kodierende nukleinsäuresequenzen und verwendung dieser polypeptide | |
| ATE125306T1 (de) | Monoklonale antikörper, die einen unterschied zwischen nativproteinen und proteinen mit einer modifizierten sequenz machen. | |
| Leathem et al. | Controlling antisera in immunohistochemistry. | |
| DK182188A (da) | Humant tumorassocieret antigen | |
| IT9006602A0 (it) | Test immunoenzimatico per la ricerca e determinazione degli anticorpi anti-ss-dna. |