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DE69315079D1 - Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure - Google Patents

Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure

Info

Publication number
DE69315079D1
DE69315079D1 DE69315079T DE69315079T DE69315079D1 DE 69315079 D1 DE69315079 D1 DE 69315079D1 DE 69315079 T DE69315079 T DE 69315079T DE 69315079 T DE69315079 T DE 69315079T DE 69315079 D1 DE69315079 D1 DE 69315079D1
Authority
DE
Germany
Prior art keywords
beta
acid
peptidylaminoalkylboric
aminoalkyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69315079T
Other languages
English (en)
Other versions
DE69315079T2 (de
Inventor
David Bjorkquist
Rajan Panandiker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of DE69315079D1 publication Critical patent/DE69315079D1/de
Publication of DE69315079T2 publication Critical patent/DE69315079T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38663Stabilised liquid enzyme compositions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69315079T 1992-08-14 1993-08-03 Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure Expired - Fee Related DE69315079T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/931,809 US5442100A (en) 1992-08-14 1992-08-14 β-aminoalkyl and β-N-peptidylaminoalkyl boronic acids
PCT/US1993/007276 WO1994004542A1 (en) 1992-08-14 1993-08-03 β-AMINOALKYL AND β-N-PEPTIDYLAMINOALKYL BORONIC ACIDS

Publications (2)

Publication Number Publication Date
DE69315079D1 true DE69315079D1 (de) 1997-12-11
DE69315079T2 DE69315079T2 (de) 1998-06-04

Family

ID=25461390

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69315079T Expired - Fee Related DE69315079T2 (de) 1992-08-14 1993-08-03 Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure

Country Status (10)

Country Link
US (2) US5442100A (de)
EP (1) EP0655067B1 (de)
JP (1) JPH08500113A (de)
CN (1) CN1047596C (de)
AT (1) ATE159945T1 (de)
AU (1) AU4799793A (de)
DE (1) DE69315079T2 (de)
MX (1) MX9304970A (de)
TW (1) TW251274B (de)
WO (1) WO1994004542A1 (de)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE149563T1 (de) * 1992-08-14 1997-03-15 Procter & Gamble Alpha-aminoborsäurehaltige flüssige waschmittel
JPH09503795A (ja) * 1993-07-09 1997-04-15 ノボ ノルディスク アクティーゼルスカブ 酵素安定剤としてのボロニックアシッド又はボリニックアシッド
US5834415A (en) * 1994-04-26 1998-11-10 Novo Nordisk A/S Naphthalene boronic acids
DE4422433A1 (de) * 1994-06-28 1996-01-04 Cognis Bio Umwelt Mehrenzymgranulat
US5731439A (en) * 1995-03-24 1998-03-24 The Dupont Merck Pharmaceutical Company Piperidine containing aminobornic acids
US6086634A (en) 1995-06-05 2000-07-11 Custom Cleaner, Inc. Dry-cleaning compositions containing polysulfonic acid
AU5950696A (en) 1995-06-05 1996-12-24 Creative Products Resource, Inc. Dry-cleaning kit for in-dryer use
US5658651A (en) 1995-09-29 1997-08-19 Creative Products Resource, Inc. Fabric treatment and softener system for in-dryer use
US6036727A (en) 1995-06-05 2000-03-14 Creative Products Resource, Inc. Anhydrous dry-cleaning compositions containing polysulfonic acid, and dry-cleaning kits for delicate fabrics
ATE217342T1 (de) * 1995-06-13 2002-05-15 Novozymes As 4-substituierte-phenylboronsäuren als enzymstabilisatoren
WO2000076974A2 (en) * 1999-06-14 2000-12-21 Wisconsin Alumni Research Foundation Oligomers and polymers of cyclic imino carboxylic acids
BRPI0515062A (pt) * 2004-09-08 2008-07-01 Procter & Gamble composições para tratamento de roupas para lavar com odor aprimorado
CN104673532A (zh) 2008-01-04 2015-06-03 宝洁公司 包含糖基水解酶的衣物洗涤剂组合物
US20090209447A1 (en) * 2008-02-15 2009-08-20 Michelle Meek Cleaning compositions
MX2010013276A (es) 2008-06-06 2010-12-21 Procter & Gamble Composicion detergente que comprende una variante de una xiloglucanasa de la familia 44.
WO2009154737A1 (en) 2008-06-17 2009-12-23 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
WO2011005730A1 (en) 2009-07-09 2011-01-13 The Procter & Gamble Company A catalytic laundry detergent composition comprising relatively low levels of water-soluble electrolyte
BR112012000531A2 (pt) 2009-07-09 2019-09-24 Procter & Gamble composição detergente para lavagem de roupas catalítica que compreende teores relativamente baixos de eletrólito solúvel em água
US20110166370A1 (en) 2010-01-12 2011-07-07 Charles Winston Saunders Scattered Branched-Chain Fatty Acids And Biological Production Thereof
BR112012023055A2 (pt) 2010-03-12 2017-07-25 Procter & Gamble amido-gelificante de ph sintonizável para uso em composições de produto destinado ao consumidor
CA2791251C (en) 2010-03-12 2014-08-12 The Procter & Gamble Company Fluid detergent compositions comprising a di-amido gellant, and processes for making
AU2011289615B2 (en) 2010-08-10 2015-05-07 Melinta Therapeutics, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CA2827627C (en) 2011-02-17 2016-10-11 The Procter & Gamble Company Compositions comprising mixtures of c10-c13 alkylphenyl sulfonates
EP2675784B1 (de) 2011-02-17 2017-09-13 The Procter and Gamble Company Biobasierte lineare alkylphenylsulfonate
EP2737043B1 (de) 2011-07-25 2017-01-04 The Procter and Gamble Company Waschmittel mit akzeptabler farbe
US20130303427A1 (en) 2011-09-13 2013-11-14 Susana Fernandez Prieto MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS
WO2013104897A1 (en) * 2012-01-09 2013-07-18 University of Tromsø Therapeutic boron-containing compounds
EP2716644B1 (de) 2012-10-03 2017-04-05 The Procter and Gamble Company Stabile Enzymstabilisatorvormischung
CN104994844A (zh) 2013-01-04 2015-10-21 莱姆派克斯制药公司 硼酸衍生物及其治疗用途
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US20160024440A1 (en) 2013-03-14 2016-01-28 Novozymes A/S Enzyme and Inhibitor Containing Water-Soluble Films
MX365786B (es) 2013-05-03 2019-06-14 Novozymes As Microencapsulacion de enzimas detergentes.
EP3139930B1 (de) 2014-05-05 2024-08-14 Melinta Therapeutics, Inc. Salze und polymorphe von cyclischen borsäureesterderivaten und therapeutische verwendungen davon
US10385074B2 (en) 2014-05-05 2019-08-20 Rempex Pharmaceuticals, Inc. Synthesis of boronate salts and uses thereof
MX2016015093A (es) 2014-05-19 2017-03-27 Rempex Pharmaceuticals Inc Derivados de acido boronico y sus usos terapeuticos.
AU2015264272A1 (en) 2014-05-20 2016-11-24 Millennium Pharmaceuticals, Inc. Boron-containing proteasome inhibitors for use after primary cancer therapy
JP6700203B2 (ja) 2014-07-01 2020-05-27 レンペックス・ファーマシューティカルズ・インコーポレイテッド ボロン酸誘導体およびその治療的使用
WO2016001319A1 (en) 2014-07-03 2016-01-07 Novozymes A/S Improved stabilization of non-protease enzyme
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
EP3234093B1 (de) 2014-12-19 2020-05-27 Novozymes A/S Proteasevarianten und dafür codierende polynukleotide
US10364257B2 (en) 2014-12-19 2019-07-30 Rempex Pharmaceuticals, Inc. Apparatus and continuous flow process for production of boronic acid derivatives
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
EP3950939A3 (de) 2015-07-06 2022-06-08 Novozymes A/S Lipasevarianten und polynukleotide zur codierung davon
EP3362168A1 (de) 2015-10-14 2018-08-22 Novozymes A/S Reinigung von wasserfiltrationsmembranen
UA124464C2 (uk) 2016-06-30 2021-09-22 Кьюпекс Біофарма, Інк. Похідні боронової кислоти та їх терапевтичні застосування
CN110651038A (zh) 2017-05-05 2020-01-03 诺维信公司 包含脂肪酶和亚硫酸盐的组合物
EP3645692A1 (de) 2017-06-30 2020-05-06 Novozymes A/S Enzymschlammzusammensetzung
IL273551B2 (en) 2017-10-11 2024-02-01 Qpex Biopharma Inc Boronic acid derivatives and their synthesis
BR112020008711A2 (pt) 2017-11-01 2020-11-10 Novozymes A/S polipeptídeos e composições que compreendem tais polipeptídeos
CN111527190A (zh) 2017-11-01 2020-08-11 诺维信公司 多肽以及包含此类多肽的组合物
CN111770788B (zh) 2018-03-13 2023-07-25 诺维信公司 使用氨基糖低聚物进行微囊化
WO2019204419A1 (en) 2018-04-20 2019-10-24 The Medicines Company (San Diego), Llc Boronic acid derivatives and therapeutic uses thereof
EP3647397A1 (de) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Reinigungsmittel mit dispersins iv
ES2981999T3 (es) 2018-10-31 2024-10-14 Henkel Ag & Co Kgaa Composiciones limpiadoras que contienen dispersinas V
US11879110B2 (en) 2019-11-27 2024-01-23 The Procter & Gamble Company Alkylbenzenesulfonate surfactants
WO2021123307A2 (en) 2019-12-20 2021-06-24 Novozymes A/S Polypeptides having proteolytic activity and use thereof
WO2022189521A1 (en) 2021-03-12 2022-09-15 Novozymes A/S Polypeptide variants
WO2024131880A2 (en) 2022-12-23 2024-06-27 Novozymes A/S Detergent composition comprising catalase and amylase

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872479A (en) * 1955-06-30 1959-02-03 Callery Chemical Co Preparation of organoboron compounds
US3912595A (en) * 1974-02-25 1975-10-14 Us Health Method of purifying enzymes using boronic acids covalently bonded to an insoluble support
IT1129814B (it) * 1980-07-02 1986-06-11 Unilever Nv Composizione detergente enzimatica liquida
US4462922A (en) * 1981-11-19 1984-07-31 Lever Brothers Company Enzymatic liquid detergent composition
GB8311314D0 (en) * 1983-04-26 1983-06-02 Unilever Plc Aqueous enzyme-containing compositions
US4652394A (en) * 1983-05-31 1987-03-24 Colgate Palmolive Co. Built single phase liquid anionic detergent compositions containing stabilized enzymes
DE3413571A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Verwendung von kristallinen schichtfoermigen natriumsilikaten zur wasserenthaertung und verfahren zur wasserenthaertung
US4537707A (en) * 1984-05-14 1985-08-27 The Procter & Gamble Company Liquid detergents containing boric acid and formate to stabilize enzymes
US4566985A (en) * 1984-09-19 1986-01-28 Applied Biochemists, Inc. Method of cleaning using liquid compositions comprising stabilized mixtures of enzymes
US4747977A (en) * 1984-11-09 1988-05-31 The Procter & Gamble Company Ethanol-free liquid laundry detergent compositions
US4900475A (en) * 1985-07-26 1990-02-13 Colgate-Palmolive Co. Stabilized built liquid detergent composition containing enzyme
US4842769A (en) * 1985-07-26 1989-06-27 Colgate-Palmolive Co. Stabilized fabric softening built detergent composition containing enzymes
US4933287A (en) * 1985-08-09 1990-06-12 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
EG18543A (en) * 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
US4842758A (en) * 1986-10-31 1989-06-27 Colgate-Palmolive Company Stabilized enzyme system for use in aqueous liquid built detergent compositions
US4704233A (en) * 1986-11-10 1987-11-03 The Procter & Gamble Company Detergent compositions containing ethylenediamine-N,N'-disuccinic acid
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
DK571587D0 (da) * 1987-11-02 1987-11-02 Novo Industri As Enzymatisk detergentsammensaetning
EP0315574A3 (de) * 1987-11-05 1990-08-22 Hoechst Aktiengesellschaft Renin-Inhibitoren
GB8810822D0 (en) * 1988-05-06 1988-06-08 Unilever Plc Liquid detergent compositions
US4963655A (en) * 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
US5039446A (en) * 1988-07-01 1991-08-13 Genencor International, Inc. Liquid detergent with stabilized enzyme
DE3840452A1 (de) * 1988-12-01 1990-06-07 Hoechst Ag (beta)-amino-boronsaeure-derivate
CA2006527A1 (en) * 1988-12-30 1990-06-30 Martin S. Cardinali Enzymatic liquid detergent compositions
US4959179A (en) * 1989-01-30 1990-09-25 Lever Brothers Company Stabilized enzymes liquid detergent composition containing lipase and protease
US4908150A (en) * 1989-02-02 1990-03-13 Lever Brothers Company Stabilized lipolytic enzyme-containing liquid detergent composition
EP0385401A1 (de) * 1989-02-27 1990-09-05 Occidental Chemical Corporation Besondere Mikrobielle Lipasen mit einer Aktivität bei Temperaturen und pH-Werten, die ihnen für die Verwendung in Detergentien Eignung verleiht
DE69033423T2 (de) * 1989-05-15 2000-05-25 The Clorox Co., Oakland Wäschewaschverfahren
EP0450702A3 (en) * 1990-04-06 1993-06-02 Unilever N.V. Process for preparing liquid enzymatic detergent compositions
EP0478050A1 (de) * 1990-09-24 1992-04-01 Unilever N.V. Detergentzusammensetzung
DK0486073T3 (da) * 1990-11-14 1996-12-09 Procter & Gamble Væskeformig detergentsammensætning, der indeholder lipase og protease

Also Published As

Publication number Publication date
EP0655067A1 (de) 1995-05-31
DE69315079T2 (de) 1998-06-04
TW251274B (de) 1995-07-11
EP0655067B1 (de) 1997-11-05
CN1090850A (zh) 1994-08-17
US5442100A (en) 1995-08-15
WO1994004542A1 (en) 1994-03-03
MX9304970A (es) 1994-05-31
JPH08500113A (ja) 1996-01-09
US5488157A (en) 1996-01-30
CN1047596C (zh) 1999-12-22
AU4799793A (en) 1994-03-15
ATE159945T1 (de) 1997-11-15

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