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DE69831605D1 - Anti-östrogen- und progestin-enthaltende orale kontrazeptiva - Google Patents

Anti-östrogen- und progestin-enthaltende orale kontrazeptiva

Info

Publication number
DE69831605D1
DE69831605D1 DE69831605T DE69831605T DE69831605D1 DE 69831605 D1 DE69831605 D1 DE 69831605D1 DE 69831605 T DE69831605 T DE 69831605T DE 69831605 T DE69831605 T DE 69831605T DE 69831605 D1 DE69831605 D1 DE 69831605D1
Authority
DE
Germany
Prior art keywords
contrazeptiva
progestine
estrogen
containing oral
oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831605T
Other languages
English (en)
Other versions
DE69831605T2 (de
Inventor
Jay Gast
Paul Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of DE69831605D1 publication Critical patent/DE69831605D1/de
Application granted granted Critical
Publication of DE69831605T2 publication Critical patent/DE69831605T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69831605T 1997-11-06 1998-11-04 Anti-östrogen- und progestin-enthaltende orale kontrazeptiva Expired - Lifetime DE69831605T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96508397A 1997-11-06 1997-11-06
PCT/US1998/023427 WO1999024027A2 (en) 1997-11-06 1998-11-04 Anti-estrogen plus progestin containing oral contraceptives

Publications (2)

Publication Number Publication Date
DE69831605D1 true DE69831605D1 (de) 2005-10-20
DE69831605T2 DE69831605T2 (de) 2006-06-14

Family

ID=25509417

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831605T Expired - Lifetime DE69831605T2 (de) 1997-11-06 1998-11-04 Anti-östrogen- und progestin-enthaltende orale kontrazeptiva

Country Status (28)

Country Link
EP (1) EP1051179B1 (de)
JP (1) JP2001522798A (de)
CN (1) CN1278732A (de)
AR (1) AR016667A1 (de)
AT (1) ATE304359T1 (de)
AU (2) AU760540B2 (de)
BG (1) BG104451A (de)
BR (1) BR9813982A (de)
CA (1) CA2307210A1 (de)
CZ (1) CZ294155B6 (de)
DE (1) DE69831605T2 (de)
DK (1) DK1051179T3 (de)
EA (1) EA200000492A1 (de)
EE (1) EE04092B1 (de)
ES (1) ES2246541T3 (de)
GE (1) GEP20043290B (de)
HR (1) HRP20000269A2 (de)
HU (1) HUP0100293A3 (de)
ID (1) ID24568A (de)
IL (1) IL135621A0 (de)
NO (1) NO20002167L (de)
NZ (1) NZ503890A (de)
PL (1) PL340623A1 (de)
SK (1) SK6482000A3 (de)
TR (1) TR200001268T2 (de)
UA (1) UA68365C2 (de)
WO (1) WO1999024027A2 (de)
ZA (1) ZA9810136B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL120263A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to prevent bone loss-progesterone and estrogen agonists
US6479535B1 (en) 1998-05-15 2002-11-12 Wyeth 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations
GEP20033079B (en) * 1998-05-15 2003-10-27 Wyeth Corp Pharmaceutical Compositions for Treatment of Diseases Caused by Estrogens Deficiency
EP1212335B1 (de) * 1999-09-13 2006-01-18 Wyeth Glucopyranosid-konjugate von 2-(4-hydroxy-phenyl)-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1h-indol-5-olen
US6380166B1 (en) 1999-09-13 2002-04-30 American Home Products Corporation Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
US6376486B1 (en) 2000-07-06 2002-04-23 American Home Products Corporation Methods of inhibiting sphincter incontinence
CZ2004118A3 (cs) 2001-07-31 2004-09-15 Pfizer Products Inc. Farmaceutický prostředek, kit a způsoby zahrnující kombinaci činidla estrogenový agonist/antagonist, estrogenu a progestinu
SI1809602T1 (sl) * 2004-10-27 2009-04-30 Janssen Pharmaceutica Nv Indolni derivati, uporabni kot modulatorji progesteronskega receptorja
FR2880625B1 (fr) * 2005-01-07 2007-03-09 Sanofi Aventis Sa Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
UY29527A1 (es) 2005-05-13 2006-12-29 Schering Ag Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato.
DE102008057230A1 (de) * 2008-11-11 2010-05-12 Bayer Schering Pharma Aktiengesellschaft Synergistische pharmazeutische Kombination mit einem Estrogenrezeptorantagonisten und einem Progestin
CN102939287B (zh) 2010-06-10 2016-01-27 塞拉根制药公司 雌激素受体调节剂及其用途
JP2015500346A (ja) 2011-12-14 2015-01-05 セラゴン ファーマシューティカルズ，インク． エストロゲン受容体モジュレーターおよびその使用
KR102710603B1 (ko) 2015-10-01 2024-09-27 올레마 파마슈티컬스 인코포레이티드 테트라히드로-1H-피리도[3,4-b]인돌 항에스트로겐 약물
CN108495628B (zh) 2015-12-09 2022-01-11 伊利诺伊大学评议会 苯并噻吩基选择性雌激素受体下调剂
CN109562113A (zh) 2016-05-10 2019-04-02 C4医药公司 用于靶蛋白降解的螺环降解决定子体
EP3454856B1 (de) 2016-05-10 2024-09-11 C4 Therapeutics, Inc. Heterocyclische degronimere für zielproteinabbau
WO2017197046A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. C3-carbon linked glutarimide degronimers for target protein degradation
AU2017290748A1 (en) 2016-07-01 2019-01-17 G1 Therapeutics, Inc. Pyrimidine-based antiproliferative agents
WO2018081168A2 (en) 2016-10-24 2018-05-03 The Board Of Trustees Of The University Of Illinois Benzothiophene-based selective mixed estrogen receptor downregulators
JP7229162B2 (ja) 2017-01-06 2023-02-27 ジー１ セラピューティクス， インコーポレイテッド 癌の治療に対する併用療法
CN110461853A (zh) 2017-02-10 2019-11-15 G1治疗公司 苯并噻吩雌激素受体调节剂
AU2018291026B2 (en) 2017-06-29 2022-09-01 G1 Therapeutics, Inc. Morphic forms of GIT38 and methods of manufacture thereof
EP3897631A4 (de) 2018-12-20 2022-11-23 C4 Therapeutics, Inc. Gezielter proteinabbau
CA3154073A1 (en) 2019-12-20 2021-06-24 Christopher G. Nasveschuk Isoindolinone and indazole compounds for the degradation of egfr
JP2023516073A (ja) 2020-03-05 2023-04-17 シーフォー セラピューティクス， インコーポレイテッド Ｂｒｄ９の標的分解のための化合物
WO2024030968A1 (en) 2022-08-03 2024-02-08 Brystol-Myers Squibb Company Compounds for modulating ret protein
WO2024097989A1 (en) 2022-11-04 2024-05-10 Bristol-Myers Squibb Company Ret-ldd protein degraders
WO2024097980A1 (en) 2022-11-04 2024-05-10 Bristol-Myers Squibb Company Ret-ldd protein inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA716118B (en) * 1970-10-05 1972-05-31 Richardson Merrell Inc Contraception
ZA9510926B (en) * 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
IL120266A (en) * 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
IL120263A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to prevent bone loss-progesterone and estrogen agonists
PT802183E (pt) * 1996-04-19 2002-03-28 American Home Prod Agentes estrogenicos
US5747480A (en) * 1996-05-08 1998-05-05 American Home Products Corporation Oral contraceptive

Also Published As

Publication number Publication date
HUP0100293A3 (en) 2002-12-28
GEP20043290B (en) 2004-07-26
EE04092B1 (et) 2003-08-15
BR9813982A (pt) 2000-09-26
AU2003204896B2 (en) 2006-06-15
HUP0100293A2 (hu) 2001-10-28
TR200001268T2 (tr) 2001-01-22
NZ503890A (en) 2002-08-28
EP1051179A2 (de) 2000-11-15
AU760540B2 (en) 2003-05-15
CZ20001661A3 (cs) 2000-12-13
NO20002167L (no) 2000-06-28
EP1051179B1 (de) 2005-09-14
CN1278732A (zh) 2001-01-03
DK1051179T3 (da) 2005-10-31
CZ294155B6 (cs) 2004-10-13
EE200000211A (et) 2001-04-16
SK6482000A3 (en) 2000-11-07
NO20002167D0 (no) 2000-04-27
JP2001522798A (ja) 2001-11-20
IL135621A0 (en) 2001-05-20
WO1999024027A3 (en) 1999-07-15
ES2246541T3 (es) 2006-02-16
AR016667A1 (es) 2001-07-25
AU1303199A (en) 1999-05-31
ATE304359T1 (de) 2005-09-15
EA200000492A1 (ru) 2000-10-30
WO1999024027A2 (en) 1999-05-20
BG104451A (en) 2000-12-29
DE69831605T2 (de) 2006-06-14
ID24568A (id) 2000-07-27
CA2307210A1 (en) 1999-05-20
ZA9810136B (en) 2000-05-05
UA68365C2 (en) 2004-08-16
PL340623A1 (en) 2001-02-12
HRP20000269A2 (en) 2000-12-31

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