Nothing Special   »   [go: up one dir, main page]

DE68922287D1 - Imidazol und Pyridyl-Derivate von Phenyl substituierten 1,4-Dihydropyridinen und Verfahren zu ihrer Herstellung. - Google Patents

Imidazol und Pyridyl-Derivate von Phenyl substituierten 1,4-Dihydropyridinen und Verfahren zu ihrer Herstellung.

Info

Publication number
DE68922287D1
DE68922287D1 DE68922287T DE68922287T DE68922287D1 DE 68922287 D1 DE68922287 D1 DE 68922287D1 DE 68922287 T DE68922287 T DE 68922287T DE 68922287 T DE68922287 T DE 68922287T DE 68922287 D1 DE68922287 D1 DE 68922287D1
Authority
DE
Germany
Prior art keywords
group
chem
dihydropyridines
phenyl substituted
imidazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68922287T
Other languages
English (en)
Other versions
DE68922287T2 (de
Inventor
Paolo Cozzi
Germano Carganico
Maria Menichincheri
Patrizia Salvati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888829292A external-priority patent/GB8829292D0/en
Priority claimed from GB898915222A external-priority patent/GB8915222D0/en
Application filed by Pharmacia SpA filed Critical Pharmacia SpA
Application granted granted Critical
Publication of DE68922287D1 publication Critical patent/DE68922287D1/de
Publication of DE68922287T2 publication Critical patent/DE68922287T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE68922287T 1988-12-15 1989-12-14 Imidazol und Pyridyl-Derivate von Phenyl substituierten 1,4-Dihydropyridinen und Verfahren zu ihrer Herstellung. Expired - Fee Related DE68922287T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888829292A GB8829292D0 (en) 1988-12-15 1988-12-15 Imidazolyl derivatives of phenyl substituted 1 4-dihydro-pyridines and process for their preparation
GB898915222A GB8915222D0 (en) 1989-07-03 1989-07-03 Pyridyl derivatives of phenyl substituted 1,4-dihydro-pyridines and process for their preparation

Publications (2)

Publication Number Publication Date
DE68922287D1 true DE68922287D1 (de) 1995-05-24
DE68922287T2 DE68922287T2 (de) 1995-08-24

Family

ID=26294734

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922287T Expired - Fee Related DE68922287T2 (de) 1988-12-15 1989-12-14 Imidazol und Pyridyl-Derivate von Phenyl substituierten 1,4-Dihydropyridinen und Verfahren zu ihrer Herstellung.

Country Status (14)

Country Link
EP (2) EP0403627A1 (de)
JP (1) JPH03502702A (de)
KR (1) KR910700246A (de)
AT (1) ATE121399T1 (de)
AU (1) AU628117B2 (de)
CA (1) CA2005490A1 (de)
DE (1) DE68922287T2 (de)
DK (1) DK193090A (de)
FI (1) FI903995A0 (de)
HU (1) HU205349B (de)
IL (1) IL92646A0 (de)
NZ (1) NZ231747A (de)
PT (1) PT92578B (de)
WO (1) WO1990006923A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2036128B1 (es) * 1991-07-10 1993-12-16 Menarini Lab Procedimiento para la preparacion de 4-(imidazo)1,5-a)piridin-8l)-1,4-dihidropiridinas.
GB9119983D0 (en) * 1991-09-19 1991-11-06 Erba Carlo Spa Dihydropyridine derivatives useful in antitumor therapy
DE59304885D1 (de) * 1992-10-30 1997-02-06 Bayer Ag 4-Heterocyclophenyl substituierte Dihydropyridine
GB9515445D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa Dihydropyridine and pyridine derivatives and process for their preparation
GB2310136A (en) * 1996-02-16 1997-08-20 Pharmacia Spa Dihydropyridine derivatives as aromatase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946028A (en) * 1972-09-30 1976-03-23 Bayer Aktiengesellschaft 2,3,5,6-Tetracarboxy-4-pyridyl-1,4-dihydropyridine derivatives
DE2844348C2 (de) * 1978-10-11 1985-10-03 Kaltenbach & Voigt Gmbh & Co, 7950 Biberach Zahnärztlicher Behandlungsplatz
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
JPS611137A (ja) * 1984-06-14 1986-01-07 Matsushita Electric Works Ltd 多重操作形操作盤
JPS6168626A (ja) * 1984-09-12 1986-04-09 Hitachi Ltd 画像入出力装置
IT1201454B (it) * 1985-08-19 1989-02-02 Boehringer Biochemia Srl 1,4-diidropiridine-2-sostituite
IT1204459B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici

Also Published As

Publication number Publication date
JPH03502702A (ja) 1991-06-20
EP0373645B1 (de) 1995-04-19
HU205349B (en) 1992-04-28
ATE121399T1 (de) 1995-05-15
PT92578B (pt) 1995-09-12
DE68922287T2 (de) 1995-08-24
EP0373645A1 (de) 1990-06-20
HU900402D0 (en) 1991-02-28
FI903995A0 (fi) 1990-08-13
HUT55009A (en) 1991-04-29
CA2005490A1 (en) 1990-06-15
AU628117B2 (en) 1992-09-10
PT92578A (pt) 1990-06-29
DK193090A (da) 1990-10-09
EP0403627A1 (de) 1990-12-27
KR910700246A (ko) 1991-03-14
WO1990006923A1 (en) 1990-06-28
IL92646A0 (en) 1990-08-31
AU4666289A (en) 1990-07-10
NZ231747A (en) 1991-03-26
DK193090D0 (da) 1990-08-14

Similar Documents

Publication Publication Date Title
ATE18910T1 (de) Succinimid-derivate und verfahren zu ihrer herstellung.
HUT62571A (en) Pesticidal compositions comprising 1-(2-pyridyl)-pyrazole compounds as active ingredient and process for producing 1-(2-pyridil)-pyrazole derivatives
FI874451A (fi) Menetelmä lääkeaineina käyttökelpoisten dihydropyridiinin johdannaisten valmistamiseksi
ES2176311T3 (es) Nuevos derivados imidazol y procedimiento para su preparacion.
DE69923300D1 (de) Cycloalken-derivate, verfahren zu ihrer herstellung und ihre verwendung
FI863019A (fi) Foerfarande foer framstaellning av heterocykliska foereningar.
FI863020A0 (fi) Foerfarande foer framstaellning av heterocykliska foereningar.
KR870002122A (ko) 1,4-디하이드로피리딘 유도체의 제조방법
EP0997462A4 (de) Naphthyridinderivate oder salze davon
AT389108B (de) Neue pyridazinonderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
FI924110A0 (fi) Menetelmä dihydropyridiinijohdannaisten valmistamiseksi, jotka ovat käyttökelpoisia kasvainten vastaisessa terapiassa
DE68922287D1 (de) Imidazol und Pyridyl-Derivate von Phenyl substituierten 1,4-Dihydropyridinen und Verfahren zu ihrer Herstellung.
ES2091489T3 (es) Derivados de imidazol y composiciones farmaceuticas que los contienen.
ATE75737T1 (de) Indenothiazolderivate und verfahren zu ihrer herstellung.
DE69324854D1 (de) Pyridazinone-Derivate und Verfahren zur deren Herstellung
KR890016018A (ko) 6-옥소-피리다진 유도체류, 이들 화합물의 제조방법과 그 함유 의약품
DK0613896T3 (da) Fremgangsmåde til fremstilling af sulfonylurinstofderivater
TW350843B (en) 2-(4-pyrazolyloxy-pyrimidin-5-yl) acetic acid derivatives
MY128754A (en) Substituted 3-aryl-3-carboxyalkyl glutaramides, method for preparing same by 4-aryl-4-cyanoheptane dicarboxylic acid cyclisation, and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines
AU7332996A (en) Therapeutics for thrombocytopenia
ATE30911T1 (de) Hydrazinopyridazinverbindung, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE131480T1 (de) Pyrimidoindolderivate und verfahren zu ihrer herstellung
PT868428E (pt) Derivados de acido fosfonico possuindo actividade inibidora da metalopeptidase
MY104164A (en) Heterocyclic compounds.
TH3370EX (th) กรรมวิธีสำหรับการเตรียมสารประกอบเฮเทอโรไซคลิค

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee