DE602005019398D1 - LIQUIDS WITH SUSPENDED GLASS PARTICLES - Google Patents
LIQUIDS WITH SUSPENDED GLASS PARTICLESInfo
- Publication number
- DE602005019398D1 DE602005019398D1 DE602005019398T DE602005019398T DE602005019398D1 DE 602005019398 D1 DE602005019398 D1 DE 602005019398D1 DE 602005019398 T DE602005019398 T DE 602005019398T DE 602005019398 T DE602005019398 T DE 602005019398T DE 602005019398 D1 DE602005019398 D1 DE 602005019398D1
- Authority
- DE
- Germany
- Prior art keywords
- liquids
- particles
- glass particles
- suspended
- suspended glass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 239000011521 glass Substances 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 title abstract 2
- 229920001774 Perfluoroether Polymers 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- 150000007942 carboxylates Chemical class 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- GVGCUCJTUSOZKP-UHFFFAOYSA-N nitrogen trifluoride Chemical compound FN(F)F GVGCUCJTUSOZKP-UHFFFAOYSA-N 0.000 abstract 1
- UJMWVICAENGCRF-UHFFFAOYSA-N oxygen difluoride Chemical compound FOF UJMWVICAENGCRF-UHFFFAOYSA-N 0.000 abstract 1
- 239000010702 perfluoropolyether Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- QTJXVIKNLHZIKL-UHFFFAOYSA-N sulfur difluoride Chemical compound FSF QTJXVIKNLHZIKL-UHFFFAOYSA-N 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Glass Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A pharmaceutical composition comprising a biologically active agent preserved in particulate form, in particular a glass or amorphous particle, such as a sugar, a metal carboxylate, an amino acid or calcium phosphate, wherein said particles are suspended in at least one of a hydrofluoroether, a perfluoroether, a hydrofluoroamine, a perfluoroamine, a hydrofluorothioether, a perfluorothioether, a hydrofluoropolyether or a perfluoropolyether. The use of such fluorinated liquid media overcomes the problem of aggregation of particles and also is environmentally friendly.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0408199.8A GB0408199D0 (en) | 2004-04-13 | 2004-04-13 | Liquids containing suspended sugar glass particles |
| GB0504501A GB2413075B (en) | 2004-04-13 | 2005-03-07 | Liquids containing suspended glass particles |
| PCT/GB2005/050050 WO2005099669A1 (en) | 2004-04-13 | 2005-04-13 | Liquids containing suspended glass particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005019398D1 true DE602005019398D1 (en) | 2010-04-01 |
Family
ID=32320732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005019398T Active DE602005019398D1 (en) | 2004-04-13 | 2005-04-13 | LIQUIDS WITH SUSPENDED GLASS PARTICLES |
Country Status (10)
| Country | Link |
|---|---|
| CN (1) | CN1942171B (en) |
| AT (1) | ATE457717T1 (en) |
| DE (1) | DE602005019398D1 (en) |
| DK (1) | DK1750668T3 (en) |
| ES (1) | ES2339783T3 (en) |
| GB (2) | GB0408199D0 (en) |
| MX (1) | MXPA06011895A (en) |
| PT (1) | PT1750668E (en) |
| RU (1) | RU2363447C2 (en) |
| ZA (1) | ZA200609158B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0517688D0 (en) * | 2005-08-31 | 2005-10-05 | Cambridge Biostability Ltd | Improvements in the stabilisation of biological materials |
| GB0523638D0 (en) | 2005-11-21 | 2005-12-28 | Cambridge Biostability Ltd | Pharmaceutical device for the administration of substances to patients |
| US9243626B2 (en) * | 2012-11-19 | 2016-01-26 | Nordson Corporation | Adhesive dispensing system and method including a pump with integrated diagnostics |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07258027A (en) * | 1994-03-16 | 1995-10-09 | Shiseido Co Ltd | Makeup cosmetic |
| US6433040B1 (en) * | 1997-09-29 | 2002-08-13 | Inhale Therapeutic Systems, Inc. | Stabilized bioactive preparations and methods of use |
| US6190701B1 (en) * | 1999-03-17 | 2001-02-20 | Peter M. Ronai | Composition and method for stable injectable liquids |
| WO2001037804A2 (en) * | 1999-11-22 | 2001-05-31 | Universal Preservation Technologies, Inc. | Preservation and formulation of bioactive materials |
| JP2004513093A (en) * | 2000-10-13 | 2004-04-30 | ケンブリッジ、バイオスタビリティー、リミテッド | Compositions and methods for stable injections |
-
2004
- 2004-04-13 GB GBGB0408199.8A patent/GB0408199D0/en not_active Ceased
-
2005
- 2005-03-07 GB GB0504501A patent/GB2413075B/en active Active
- 2005-04-13 RU RU2006137275/15A patent/RU2363447C2/en not_active IP Right Cessation
- 2005-04-13 CN CN2005800110373A patent/CN1942171B/en not_active Expired - Fee Related
- 2005-04-13 AT AT05731023T patent/ATE457717T1/en not_active IP Right Cessation
- 2005-04-13 ES ES05731023T patent/ES2339783T3/en active Active
- 2005-04-13 PT PT05731023T patent/PT1750668E/en unknown
- 2005-04-13 MX MXPA06011895A patent/MXPA06011895A/en unknown
- 2005-04-13 DK DK05731023.7T patent/DK1750668T3/en active
- 2005-04-13 DE DE602005019398T patent/DE602005019398D1/en active Active
-
2006
- 2006-11-03 ZA ZA200609158A patent/ZA200609158B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1750668T3 (en) | 2010-05-10 |
| GB2413075A (en) | 2005-10-19 |
| PT1750668E (en) | 2010-04-07 |
| MXPA06011895A (en) | 2007-11-20 |
| RU2006137275A (en) | 2008-05-20 |
| GB2413075B (en) | 2009-01-21 |
| ZA200609158B (en) | 2008-06-25 |
| GB0504501D0 (en) | 2005-04-13 |
| CN1942171A (en) | 2007-04-04 |
| CN1942171B (en) | 2011-04-06 |
| GB0408199D0 (en) | 2004-05-19 |
| ATE457717T1 (en) | 2010-03-15 |
| ES2339783T3 (en) | 2010-05-25 |
| RU2363447C2 (en) | 2009-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |