DE2963797D1 - Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals - Google Patents

Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals

Info

Publication number: DE2963797D1
Authority: DE; Germany
Prior art keywords: dibenzopyrans; pharmaceuticals; amino; preparation; formulations containing
Prior art date: 1978-02-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

DE7979300211T

Other languages

English (en)

Inventor

William Allen Day

Edward Ralph Lavagnino

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-02-17

Filing date

1979-02-12

Publication date

1982-11-11

1979-02-12 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1982-11-11 Application granted granted Critical

1982-11-11 Publication of DE2963797D1 publication Critical patent/DE2963797D1/de

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)

DE7979300211T 1978-02-17 1979-02-12 Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals Expired DE2963797D1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/878,844 US4152450A (en)	1978-02-17	1978-02-17	9-Amino-dibenzopyrans

Publications (1)

Publication Number	Publication Date
DE2963797D1 true DE2963797D1 (en)	1982-11-11

Family

ID=25372961

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE7979300211T Expired DE2963797D1 (en)	1978-02-17	1979-02-12	Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals

Country Status (29)

Country	Link
US (1)	US4152450A (de)
EP (1)	EP0003883B1 (de)
JP (1)	JPS54122278A (de)
AR (2)	AR224359A1 (de)
AT (1)	AT366039B (de)
AU (1)	AU518718B2 (de)
BE (1)	BE873981A (de)
CA (1)	CA1111425A (de)
CH (1)	CH638800A5 (de)
CS (1)	CS207769B2 (de)
DD (1)	DD142190A5 (de)
DE (1)	DE2963797D1 (de)
DK (1)	DK68179A (de)
ES (4)	ES477832A1 (de)
FI (1)	FI790503A (de)
FR (1)	FR2417510A1 (de)
GB (1)	GB2014571B (de)
GR (1)	GR71465B (de)
HU (1)	HU180729B (de)
IE (1)	IE47999B1 (de)
IL (1)	IL56582A0 (de)
LU (1)	LU80922A1 (de)
NZ (1)	NZ189591A (de)
PH (1)	PH14622A (de)
PL (5)	PL120645B1 (de)
PT (1)	PT69202A (de)
RO (5)	RO82369A (de)
SU (1)	SU812177A3 (de)
ZA (1)	ZA79726B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4351833A (en) *	1980-07-28	1982-09-28	Pfizer Inc.	9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US4309545A (en) *	1980-07-28	1982-01-05	Pfizer Inc.	Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4841078A (en) *	1982-03-16	1989-06-20	Pfizer Inc.	Benzopyrans
US4870084A (en) *	1982-03-16	1989-09-26	Pfizer Inc.	Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4642373A (en) *	1982-03-16	1987-02-10	Pfizer Inc.	Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4863934A (en) *	1982-03-16	1989-09-05	Pfizer Inc.	Bicyclic benzo fused pyran compounds used for producing analgesia
US4473704A (en) *	1982-03-16	1984-09-25	Pfizer Inc.	Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4486428A (en) *	1982-03-16	1984-12-04	Pfizer Inc.	Bicyclic benzo fused compounds
US4442089A (en) *	1982-07-06	1984-04-10	E. R. Squibb & Sons, Inc.	Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4680404A (en) *	1983-01-13	1987-07-14	Pfizer Inc.	Benzopyrans
US5180736A (en) *	1989-03-23	1993-01-19	Warner-Lambert Company	Polycyclic amines useful as cerebrovascular agents
EP1075470B1 (de) *	1998-05-04	2003-08-13	The University Of Connecticut	Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) *	1998-06-09	2011-03-01	Alexandros Makriyannis	Inhibitors of the anandamide transporter
US7589220B2 (en) *	1998-06-09	2009-09-15	University Of Connecticut	Inhibitors of the anandamide transporter
US7161016B1 (en)	1998-11-24	2007-01-09	University Of Connecticut	Cannabimimetic lipid amides as useful medications
US7276613B1 (en)	1998-11-24	2007-10-02	University Of Connecticut	Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7741365B2 (en) *	1999-10-18	2010-06-22	University Of Connecticut	Peripheral cannabinoid receptor (CB2) selective ligands
US6900236B1 (en) *	1999-10-18	2005-05-31	University Of Connecticut	Cannabimimetic indole derivatives
US8084467B2 (en) *	1999-10-18	2011-12-27	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) *	2001-08-31	2008-07-01	University Of Connecticut	Pyrazole analogs acting on cannabinoid receptors
EP1223808B1 (de)	1999-10-18	2007-03-07	The University Of Connecticut	Für periphäre cannabinoid-rezeptoren selektive liganden
US6943266B1 (en)	1999-10-18	2005-09-13	University Of Connecticut	Bicyclic cannabinoid agonists for the cannabinoid receptor
US7119108B1 (en)	1999-10-18	2006-10-10	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
CA2435409A1 (en) *	2001-01-26	2002-08-01	University Of Connecticut	Novel cannabimimetic ligands
JP2005503998A (ja)	2001-01-29	2005-02-10	ユニバーシティオブコネチカット	受容体選択性のカンナビミメティックアミノアルキルインドール
AU2002320430A1 (en)	2001-07-13	2003-01-29	University Of Connecticut	Novel bicyclic and tricyclic cannabinoids
CN1589269A (zh) *	2001-10-26	2005-03-02	康涅狄格大学	杂1,2－二氢化茚:一类新型有效的大麻配体
EP1545502A4 (de)	2002-08-23	2008-12-24	Univ Connecticut	Keto-cannabinoide mit therapeutischen indikationen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3676462A (en) *	1970-01-08	1972-07-11	Little Inc A	7,8,9,10-TETRAHYDRO (AND 7,8,9,10,11,12-HEXAHYDRO) 6H-DIBENZO {8 b,d{9 {0 PYRANS
US3649650A (en) *	1970-02-13	1972-03-14	Little Inc A	Novel derivatives of tetrahydro-cannabinol
AU7612874A (en) *	1973-12-27	1976-06-10	Erba Carlo Spa	Benzopyran derivatives

1978
- 1978-02-17 US US05/878,844 patent/US4152450A/en not_active Expired - Lifetime
1979
- 1979-02-04 IL IL56582A patent/IL56582A0/xx unknown
- 1979-02-05 PH PH22162A patent/PH14622A/en unknown
- 1979-02-06 AU AU43983/79A patent/AU518718B2/en not_active Ceased
- 1979-02-06 CA CA320,950A patent/CA1111425A/en not_active Expired
- 1979-02-07 NZ NZ189591A patent/NZ189591A/xx unknown
- 1979-02-07 FR FR7903132A patent/FR2417510A1/fr active Granted
- 1979-02-07 BE BE1/9263A patent/BE873981A/xx not_active IP Right Cessation
- 1979-02-08 PT PT7969202A patent/PT69202A/pt unknown
- 1979-02-12 DE DE7979300211T patent/DE2963797D1/de not_active Expired
- 1979-02-12 GB GB7904934A patent/GB2014571B/en not_active Expired
- 1979-02-12 EP EP79300211A patent/EP0003883B1/de not_active Expired
- 1979-02-13 RO RO79104554A patent/RO82369A/ro unknown
- 1979-02-13 RO RO79104557A patent/RO82376A/ro unknown
- 1979-02-13 RO RO79104555A patent/RO82370A/ro unknown
- 1979-02-13 RO RO7996601A patent/RO76886A/ro unknown
- 1979-02-13 RO RO79104556A patent/RO82375A/ro unknown
- 1979-02-13 AR AR275486A patent/AR224359A1/es active
- 1979-02-14 GR GR58370A patent/GR71465B/el unknown
- 1979-02-15 JP JP1716279A patent/JPS54122278A/ja active Pending
- 1979-02-15 HU HU79EI840A patent/HU180729B/hu unknown
- 1979-02-15 FI FI790503A patent/FI790503A/fi unknown
- 1979-02-15 LU LU80922A patent/LU80922A1/xx unknown
- 1979-02-16 PL PL1979227606A patent/PL120645B1/pl unknown
- 1979-02-16 SU SU792728600A patent/SU812177A3/ru active
- 1979-02-16 AT AT0123979A patent/AT366039B/de not_active IP Right Cessation
- 1979-02-16 PL PL1979227607A patent/PL120658B1/pl unknown
- 1979-02-16 ZA ZA79726A patent/ZA79726B/xx unknown
- 1979-02-16 ES ES477832A patent/ES477832A1/es not_active Expired
- 1979-02-16 PL PL1979213479A patent/PL118576B1/pl unknown
- 1979-02-16 PL PL1979227605A patent/PL120661B1/pl unknown
- 1979-02-16 DD DD79211056A patent/DD142190A5/de unknown
- 1979-02-16 DK DK68179A patent/DK68179A/da not_active Application Discontinuation
- 1979-02-16 CH CH158279A patent/CH638800A5/fr not_active IP Right Cessation
- 1979-02-16 IE IE304/79A patent/IE47999B1/en unknown
- 1979-02-16 PL PL1979227604A patent/PL121009B1/pl unknown
- 1979-02-19 CS CS791087A patent/CS207769B2/cs unknown
- 1979-11-01 ES ES485620A patent/ES485620A0/es active Granted
- 1979-11-01 ES ES485619A patent/ES485619A0/es active Granted
- 1979-11-01 ES ES485621A patent/ES485621A1/es not_active Expired
1981
- 1981-01-07 AR AR283881A patent/AR225939A1/es active

Also Published As

Publication number	Publication date
PL120658B1 (en)	1982-03-31
GB2014571A (en)	1979-08-30
RO82370A (ro)	1983-08-03
RO82369A (ro)	1983-08-03
RO82370B (ro)	1983-07-30
ATA123979A (de)	1981-07-15
DD142190A5 (de)	1980-06-11
BE873981A (fr)	1979-08-07
AT366039B (de)	1982-03-10
PL120645B1 (en)	1982-03-31
EP0003883B1 (de)	1982-10-06
ES8502105A1 (es)	1980-07-16
ES485621A1 (es)	1980-07-01
ES8502106A1 (es)	1980-07-16
AR224359A1 (es)	1981-11-30
CH638800A5 (fr)	1983-10-14
US4152450A (en)	1979-05-01
PT69202A (en)	1979-03-01
CS207769B2 (en)	1981-08-31
AU518718B2 (en)	1981-10-15
SU812177A3 (ru)	1981-03-07
FR2417510A1 (fr)	1979-09-14
ES485619A0 (es)	1980-07-16
FI790503A (fi)	1979-08-18
LU80922A1 (fr)	1979-06-18
JPS54122278A (en)	1979-09-21
IE47999B1 (en)	1984-08-22
HU180729B (en)	1983-04-29
AR225939A1 (es)	1982-05-14
AU4398379A (en)	1979-08-23
ZA79726B (en)	1980-10-29
PH14622A (en)	1981-10-12
PL213479A1 (de)	1980-03-10
NZ189591A (en)	1980-10-08
PL121009B1 (en)	1982-04-30
RO76886A (ro)	1982-02-01
EP0003883A1 (de)	1979-09-05
CA1111425A (en)	1981-10-27
IL56582A0 (en)	1979-05-31
GB2014571B (en)	1982-11-17
IE790304L (en)	1979-08-17
DK68179A (da)	1979-09-17
ES477832A1 (es)	1980-04-01
GR71465B (de)	1983-05-30
RO82376A (ro)	1983-08-03
RO82369B (ro)	1983-07-30
PL120661B1 (en)	1982-03-31
FR2417510B1 (de)	1980-08-14
RO82375A (ro)	1983-08-03
PL118576B1 (en)	1981-10-31
ES485620A0 (es)	1980-07-16
RO82376B (ro)	1983-07-30

Publication	Publication Date	Title
DE2963797D1 (en)	1982-11-11	Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals
IL56992A (en)	1983-03-31	N-heterocyclyl-4-piperidinamines,their preparation and pharmaceutical compositions containing them
IL56774A0 (en)	1979-05-31	Arylsulfamates,their preparation and their use as hermicid
IL57708A0 (en)	1979-11-30	Aminopropoxyindole derivatives,their preparation and pharmaceutical compositions containing them
MY8500596A (en)	1985-12-31	Phenethandlamines, their formulations, preparation and use
IL57430A0 (en)	1979-09-30	Carbamimidothioates,their preparation and their use as herbicides
DE2965287D1 (en)	1983-06-01	Bis-imidazoles, their preparation and pharmaceutical compositions containing them
IL57599A0 (en)	1979-10-31	Indolealkylamines,pharmaceutical formulations containing these and processes for their preparation
IL57297A0 (en)	1979-09-30	4-amino-2-piperidinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL56614A (en)	1982-01-31	N-azolylalkyl-halogeno-acetanilides,their preparation and their use as herbicides
ZA793131B (en)	1980-11-26	Indolealkylamines,pharmaceutical formulations containing these,and processes for their preparation
IL57891A (en)	1983-09-30	Alkylthiophenoxyalkylamines,their preparation and pharmaceutical compositions containing them
IL56686A0 (en)	1979-05-31	Acylaminoalkyl-syanoguanidines,their preparation and pharmaceutical compositions containing them
IL56348A0 (en)	1979-03-12	Novel phenoxyalkylocazolines, their preparation and their use as herbicides
IL56816A0 (en)	1979-05-31	N-phenylaniline derivatives,their preparation and pharmaceutical compositions containing them
IL58620A (en)	1982-12-31	Aryltrifluoroethanol derivatives,their preparation and pharmaceutical compositions containing them
IL57754A0 (en)	1979-11-30	Benzopyranotriazoles,their preparation and pharmaceutical compositions containing them
IL57862A0 (en)	1979-11-30	1-benzoyl-3-pyridinyl ureas,their use,preparation and formulations
IL56890A0 (en)	1979-05-31	2-amino-carbazole derivatives,their preparation and pharmaceutical compositions containing them
IL56913A (en)	1982-08-31	Sprio-steroid-oxazolidinone derivatives,their preparation and pharmaceutical compositions containing them
IL56728A (en)	1981-11-30	Androstadienes,their preparation and pharmaceutical compositions containing them
DE2963868D1 (en)	1982-11-25	Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them
IL56484A0 (en)	1979-03-12	Novel phenoxyalkyloxazolines, their preparation and their use as herbicides
HK12384A (en)	1984-02-24	Novel veratramides,their preparation and pharmaceutical compositions containing them
IL56349A0 (en)	1979-03-12	3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them

Legal Events

Date	Code	Title	Description
1987-02-19	8339	Ceased/non-payment of the annual fee