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DE19375005I2 - Carboxyalkyl-dipeptid-Derivate Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzung - Google Patents

Carboxyalkyl-dipeptid-Derivate Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzung

Info

Publication number
DE19375005I2
DE19375005I2 DE1993175005 DE19375005C DE19375005I2 DE 19375005 I2 DE19375005 I2 DE 19375005I2 DE 1993175005 DE1993175005 DE 1993175005 DE 19375005 C DE19375005 C DE 19375005C DE 19375005 I2 DE19375005 I2 DE 19375005I2
Authority
DE
Germany
Prior art keywords
preparation
pharmaceutical composition
composition containing
dipeptide derivatives
carboxyalkyl dipeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE1993175005
Other languages
English (en)
Inventor
Arthur A Patchett
Elbert E Harris
Matthew J Wyvratt
Edward W Tristram
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25513965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE19375005(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE19375005I2 publication Critical patent/DE19375005I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
DE1993175005 1978-12-11 1979-12-10 Carboxyalkyl-dipeptid-Derivate Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzung Active DE19375005I2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96824978A 1978-12-11 1978-12-11

Publications (1)

Publication Number Publication Date
DE19375005I2 true DE19375005I2 (de) 2000-07-13

Family

ID=25513965

Family Applications (2)

Application Number Title Priority Date Filing Date
DE7979105015T Expired DE2966767D1 (en) 1978-12-11 1979-12-10 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them
DE1993175005 Active DE19375005I2 (de) 1978-12-11 1979-12-10 Carboxyalkyl-dipeptid-Derivate Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE7979105015T Expired DE2966767D1 (en) 1978-12-11 1979-12-10 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them

Country Status (33)

Country Link
US (2) US4374829A (de)
EP (1) EP0012401B1 (de)
JP (3) JPS5581845A (de)
KR (3) KR850000847B1 (de)
AR (1) AR231971A1 (de)
AU (1) AU530380B2 (de)
BG (6) BG39294A3 (de)
CA (4) CA1302005C (de)
CS (1) CS237311B2 (de)
DD (1) DD148770A5 (de)
DE (2) DE2966767D1 (de)
DK (1) DK165455C (de)
EG (1) EG14182A (de)
ES (2) ES486786A0 (de)
FI (1) FI68405C (de)
GR (1) GR72251B (de)
HK (1) HK27487A (de)
HU (1) HU182902B (de)
IE (1) IE48922B1 (de)
IL (1) IL58849A (de)
LU (1) LU90173I2 (de)
MA (1) MA18664A1 (de)
NL (4) NL930008I2 (de)
NO (3) NO151622C (de)
NZ (1) NZ192312A (de)
PH (1) PH24268A (de)
PL (2) PL126126B1 (de)
PT (1) PT70542A (de)
RO (4) RO85073B (de)
SU (1) SU1287756A3 (de)
YU (3) YU42655B (de)
ZA (1) ZA796688B (de)
ZW (1) ZW24479A1 (de)

Families Citing this family (387)

* Cited by examiner, † Cited by third party
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