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DD249010A5 - Verfahren zur herstellung eines chinolons - Google Patents

Verfahren zur herstellung eines chinolons Download PDF

Info

Publication number
DD249010A5
DD249010A5 DD86291288A DD29128886A DD249010A5 DD 249010 A5 DD249010 A5 DD 249010A5 DD 86291288 A DD86291288 A DD 86291288A DD 29128886 A DD29128886 A DD 29128886A DD 249010 A5 DD249010 A5 DD 249010A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
hydrogen
compound
lower alkyl
methyl
Prior art date
Application number
DD86291288A
Other languages
German (de)
English (en)
Inventor
Roy V Davies
James Fraser
Kenneth J Nichol
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����@�����@�����@����k�� filed Critical ����@�����@�����@����k��
Publication of DD249010A5 publication Critical patent/DD249010A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD86291288A 1985-06-15 1986-06-13 Verfahren zur herstellung eines chinolons DD249010A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858515209A GB8515209D0 (en) 1985-06-15 1985-06-15 Therapeutic agents

Publications (1)

Publication Number Publication Date
DD249010A5 true DD249010A5 (de) 1987-08-26

Family

ID=10580805

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86291288A DD249010A5 (de) 1985-06-15 1986-06-13 Verfahren zur herstellung eines chinolons

Country Status (19)

Country Link
US (1) US4772614A (da)
EP (1) EP0206616A3 (da)
JP (1) JPS6236361A (da)
KR (1) KR870000302A (da)
CN (1) CN86104611A (da)
AU (1) AU5838286A (da)
DD (1) DD249010A5 (da)
DK (1) DK272386A (da)
ES (1) ES8801211A1 (da)
FI (1) FI862519A (da)
GB (1) GB8515209D0 (da)
GR (1) GR861528B (da)
HU (1) HUT42073A (da)
IL (1) IL79039A0 (da)
JO (1) JO1483B1 (da)
NO (1) NO862372L (da)
PH (1) PH22992A (da)
PT (1) PT82760B (da)
ZA (1) ZA864288B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172004B1 (en) * 1984-08-15 1990-03-21 The Boots Company PLC Quinolinones, process for their preparation and pharmaceutical compositions containing them
GB8627698D0 (en) * 1986-11-20 1986-12-17 Boots Co Plc Therapeutic agents
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
US5081121A (en) * 1988-05-24 1992-01-14 Tatsushi Osawa 4(1h)-quinolone derivatives
GB8918952D0 (en) * 1989-08-19 1989-10-04 Boots Co Plc Therapeutic agents
US5927566A (en) * 1996-07-11 1999-07-27 Aptargroup, Inc. One-piece dispensing system and method for making same
CA2339484A1 (en) * 1998-08-03 2000-02-17 Robert A. O'brien Pyridinones for the treatment of sexual dysfunction
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
JP2006514102A (ja) * 2002-11-07 2006-04-27 アストラゼネカ アクチボラグ 2−オキソ−エタンスルホンアミド誘導体
CN103864680B (zh) * 2012-12-12 2015-09-02 王子厚 具有抗肿瘤活性的氯氧喹衍生物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4913185A (da) * 1972-06-02 1974-02-05
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
US4552884A (en) * 1984-01-13 1985-11-12 The Boots Company Plc Method of treating heart disease
EP0172004B1 (en) * 1984-08-15 1990-03-21 The Boots Company PLC Quinolinones, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
CN86104611A (zh) 1988-01-27
JO1483B1 (en) 1988-03-10
NO862372L (no) 1986-12-16
IL79039A0 (en) 1986-09-30
FI862519A (fi) 1986-12-16
GR861528B (en) 1986-10-10
ES8801211A1 (es) 1987-12-16
NO862372D0 (no) 1986-06-13
FI862519A0 (fi) 1986-06-12
DK272386D0 (da) 1986-06-10
US4772614A (en) 1988-09-20
JPS6236361A (ja) 1987-02-17
GB8515209D0 (en) 1985-07-17
EP0206616A3 (en) 1988-06-01
DK272386A (da) 1986-12-16
AU5838286A (en) 1986-12-18
PT82760A (en) 1986-07-01
PH22992A (en) 1989-02-24
ZA864288B (en) 1987-01-28
ES556027A0 (es) 1987-12-16
KR870000302A (ko) 1987-02-17
PT82760B (en) 1988-05-19
EP0206616A2 (en) 1986-12-30
HUT42073A (en) 1987-06-29

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