Nothing Special   »   [go: up one dir, main page]

CY1124954T1 - Πλατφορμες διαλογης χημικα κωδικοποιημενων και χωρικα τοποθετημενων βιβλιοθηκων - Google Patents

Πλατφορμες διαλογης χημικα κωδικοποιημενων και χωρικα τοποθετημενων βιβλιοθηκων

Info

Publication number
CY1124954T1
CY1124954T1 CY20221100054T CY221100054T CY1124954T1 CY 1124954 T1 CY1124954 T1 CY 1124954T1 CY 20221100054 T CY20221100054 T CY 20221100054T CY 221100054 T CY221100054 T CY 221100054T CY 1124954 T1 CY1124954 T1 CY 1124954T1
Authority
CY
Cyprus
Prior art keywords
libraries
spotted
screening platforms
chemically encoded
screening
Prior art date
Application number
CY20221100054T
Other languages
English (en)
Inventor
Jacob Berlin
Gregory Copeland
Kathleen ELISON
Hurik MURADYAN
Original Assignee
City Of Hope
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56789474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1124954(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by City Of Hope filed Critical City Of Hope
Publication of CY1124954T1 publication Critical patent/CY1124954T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/16Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Structural Engineering (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Στο παρόν παρέχονται κωδικοποιημένες βιβλιοθήκες δεξαμενής διαχωρισμού, οι οποίες είναι χρήσιμες, μεταξύ άλλων, στον σχηματισμό πολύ διαφορετικών και πυκνών συστοιχιών για διαλογή και ανίχνευση μιας ποικιλίας μορίων.
CY20221100054T 2015-02-24 2022-01-21 Πλατφορμες διαλογης χημικα κωδικοποιημενων και χωρικα τοποθετημενων βιβλιοθηκων CY1124954T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562120262P 2015-02-24 2015-02-24
PCT/US2016/019426 WO2016138184A1 (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms

Publications (1)

Publication Number Publication Date
CY1124954T1 true CY1124954T1 (el) 2023-01-05

Family

ID=56789474

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20221100054T CY1124954T1 (el) 2015-02-24 2022-01-21 Πλατφορμες διαλογης χημικα κωδικοποιημενων και χωρικα τοποθετημενων βιβλιοθηκων

Country Status (18)

Country Link
US (6) US10760181B2 (el)
EP (4) EP3650459B1 (el)
JP (2) JP6872501B2 (el)
AU (2) AU2016222755B2 (el)
CA (1) CA2976946C (el)
CY (1) CY1124954T1 (el)
DK (3) DK3650458T5 (el)
ES (3) ES2904997T3 (el)
FI (2) FI3650459T3 (el)
HR (3) HRP20231536T1 (el)
HU (3) HUE058813T2 (el)
LT (3) LT3262059T (el)
NZ (1) NZ734644A (el)
PL (3) PL3650458T3 (el)
PT (3) PT3650459T (el)
RS (3) RS64899B1 (el)
SI (3) SI3262059T1 (el)
WO (1) WO2016138184A1 (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009069203A1 (ja) * 2007-11-28 2009-06-04 Glory Ltd. チケット処理装置、チケット処理システム及びチケット処理方法
AU2016222755B2 (en) * 2015-02-24 2021-02-18 City Of Hope Chemically encoded spatially addressed library screening platforms
CN106048736B (zh) * 2015-04-14 2019-09-03 成都先导药物开发股份有限公司 一种固相合成dna编码化合物库的方法
KR102355956B1 (ko) * 2016-11-08 2022-01-25 난나 테라퓨틱스 리미티드 암호화된 태그리스 화학 라이브러리
CA3076747A1 (en) 2017-09-25 2019-03-28 Plexium, Inc. Oligonucleotide encoded chemical libraries
JP7253833B2 (ja) * 2017-10-31 2023-04-07 エンコディア, インコーポレイテッド 核酸エンコーディングおよび/または標識を使用する方法およびキット
JP2022552194A (ja) 2019-10-10 2022-12-15 1859,インク. マイクロ流体スクリーニングのための方法およびシステム
WO2022170034A1 (en) * 2021-02-05 2022-08-11 Affinergy, Llc Rapid assay for apol1 g0 protein
JP7502835B2 (ja) * 2021-08-27 2024-06-19 国立大学法人神戸大学 基材上に収率よく空孔を形成する技術のためのコアシェル鋳型分子・粒子

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672040A (en) 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
EP0773227A1 (en) 1991-09-18 1997-05-14 Affymax Technologies N.V. Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5565324A (en) 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
CA2151473A1 (en) 1992-12-11 1994-06-23 Ronald N . Zuckermann Synthesis of encoded polymers
DE69432147T2 (de) * 1993-05-27 2003-11-27 Selectide Corp., Tucson Topologisch getrennte kodierende festphasen-bibliotheken
US5635598A (en) * 1993-06-21 1997-06-03 Selectide Corporation Selectively cleavabe linners based on iminodiacetic acid esters for solid phase peptide synthesis
US6087186A (en) 1993-07-16 2000-07-11 Irori Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
JPH09508353A (ja) * 1993-11-02 1997-08-26 アフィマックス テクノロジーズ ナムローゼ フェンノートシャップ 分子多様性の合成及びスクリーニング
US6936477B2 (en) 1994-04-13 2005-08-30 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US7615368B1 (en) 1994-06-17 2009-11-10 The Board Of Trustees Of The Leland Stanford Junior University Microarrays of polypeptides
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5846839A (en) 1995-12-22 1998-12-08 Glaxo Group Limited Methods for hard-tagging an encoded synthetic library
ATE366418T1 (de) 1996-04-25 2007-07-15 Bioarray Solutions Ltd Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
JP2002514046A (ja) * 1996-07-08 2002-05-14 バースタイン テクノロジーズ,インコーポレイティド 切断可能なシグナル因子の装置および方法
AU746737B2 (en) * 1996-11-06 2002-05-02 Sequenom, Inc. Compositions and methods for immobilizing nucleic acids to solid supports
AU754952B2 (en) * 1998-06-24 2002-11-28 Illumina, Inc. Decoding of array sensors with microspheres
US6429027B1 (en) * 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
US20020150909A1 (en) * 1999-02-09 2002-10-17 Stuelpnagel John R. Automated information processing in randomly ordered arrays
US6824987B1 (en) 1999-05-11 2004-11-30 President And Fellows Of Harvard College Small molecule printing
US7932213B2 (en) 1999-05-11 2011-04-26 President And Fellows Of Harvard College Small molecule printing
US6544732B1 (en) 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
US7160735B2 (en) 2000-04-28 2007-01-09 Monogram Biosciences, Inc. Tagged microparticle compositions and methods
JP3899831B2 (ja) 2001-03-02 2007-03-28 株式会社日立製作所 生化学センサ及びこれを用いた生化学検査装置
US20060040286A1 (en) 2001-03-28 2006-02-23 Nanosphere, Inc. Bio-barcode based detection of target analytes
US20030027221A1 (en) 2001-04-06 2003-02-06 Scott Melissa E. High-throughput screening assays by encapsulation
US20030228619A1 (en) 2002-06-10 2003-12-11 Xenoport, Inc. Peptide nucleic acids as tags in encoded libraries
CA2565967A1 (en) 2004-06-10 2005-12-29 Perkinelmer Las, Inc. Multiplexing assays for analyte detection
US20060134697A1 (en) * 2004-10-28 2006-06-22 The Regents Of The University Of California Method of preparing coded compound libraries
JP2009513948A (ja) * 2005-09-16 2009-04-02 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 検体検出のための比色バイオバーコード増幅アッセイ
MX2011008383A (es) 2009-02-10 2011-09-06 Idera Pharmaceuticals Inc Agonistas basados en acido ribonucleico sintetico de receptor 7 tipo toll.
US9172561B2 (en) 2009-07-29 2015-10-27 Qualcomm Incorporated Adaptive transmissions in coordinated multiple point communications
EP2460011A2 (en) 2009-07-31 2012-06-06 Prognosys Biosciences, Inc. Assay tools and methods of use
US20130059741A1 (en) * 2010-05-13 2013-03-07 Illumina, Inc. Binding assays for markers
CA2881602A1 (en) * 2012-08-14 2014-02-20 Angiochem Inc. Peptide-dendrimer conjugates and uses thereof
US20150204857A1 (en) * 2012-08-23 2015-07-23 Stemcell Technologies Inc. Compositions and Methods for Rapid and Reversible Biomolecular Labeling
AU2016222755B2 (en) 2015-02-24 2021-02-18 City Of Hope Chemically encoded spatially addressed library screening platforms

Also Published As

Publication number Publication date
HUE063406T2 (hu) 2024-01-28
EP3650458A1 (en) 2020-05-13
HRP20230928T1 (hr) 2023-11-24
US20200378031A1 (en) 2020-12-03
CA2976946C (en) 2023-09-19
ES2965764T3 (es) 2024-04-16
US11015265B2 (en) 2021-05-25
SI3650459T1 (sl) 2024-04-30
EP4276059A3 (en) 2024-05-01
AU2016222755A1 (en) 2017-08-31
SI3262059T1 (sl) 2022-04-29
HUE064689T2 (hu) 2024-04-28
CA2976946A1 (en) 2016-09-01
ES2904997T3 (es) 2022-04-06
LT3650459T (lt) 2023-12-27
US11015266B2 (en) 2021-05-25
EP3650458B1 (en) 2023-08-09
JP6872501B2 (ja) 2021-05-19
HRP20231536T1 (hr) 2024-03-15
FI3650458T3 (fi) 2023-08-21
DK3650458T5 (da) 2024-08-26
AU2016222755B2 (en) 2021-02-18
ES2954467T3 (es) 2023-11-22
LT3650458T (lt) 2023-10-10
JP2018505700A (ja) 2018-03-01
AU2021200399A1 (en) 2021-03-18
RS62847B1 (sr) 2022-02-28
EP3650459A1 (en) 2020-05-13
HUE058813T2 (hu) 2022-09-28
EP4276059A2 (en) 2023-11-15
DK3262059T3 (da) 2022-01-31
US20180245241A1 (en) 2018-08-30
US20220341059A1 (en) 2022-10-27
AU2021200399B2 (en) 2023-04-20
FI3650459T3 (fi) 2023-11-28
PL3650458T3 (pl) 2023-11-06
US10760181B2 (en) 2020-09-01
DK3650459T5 (da) 2024-08-26
HRP20220093T1 (hr) 2022-04-15
JP7109618B6 (ja) 2022-08-22
RS64567B1 (sr) 2023-10-31
JP2021106607A (ja) 2021-07-29
PT3262059T (pt) 2022-01-27
DK3650458T3 (da) 2023-09-04
PL3262059T3 (pl) 2022-02-21
US20190390367A1 (en) 2019-12-26
US20210324538A1 (en) 2021-10-21
SI3650458T1 (sl) 2023-11-30
LT3262059T (lt) 2022-02-25
EP3262059B1 (en) 2022-01-05
PT3650459T (pt) 2023-12-06
PL3650459T3 (pl) 2024-02-26
NZ734644A (en) 2023-02-24
WO2016138184A1 (en) 2016-09-01
RS64899B1 (sr) 2023-12-29
US20200378032A1 (en) 2020-12-03
US10767278B2 (en) 2020-09-08
EP3262059A1 (en) 2018-01-03
PT3650458T (pt) 2023-08-31
DK3650459T3 (da) 2023-12-11
EP3262059A4 (en) 2018-12-05
JP7109618B2 (ja) 2022-07-29
EP3650459B1 (en) 2023-09-06

Similar Documents

Publication Publication Date Title
CY1124954T1 (el) Πλατφορμες διαλογης χημικα κωδικοποιημενων και χωρικα τοποθετημενων βιβλιοθηκων
MA48740A (fr) Système de carreaux à usages multiples
MA49914A (fr) Procédés analytiques par hplc
DK3458083T3 (da) Polynukleotider, der koder for interleukin-12 (il12), og anvendelser heraf
EP3433373A4 (en) DNA COMBINATION SCREEN
EP3474669A4 (en) PROCESS FOR GENERATING COMBINATORY BARCODED LIBRARIES
DK3475295T3 (da) Hidtil ukendt nukleosidtriphosphat-transportør og anvendelser deraf
DK3795177T3 (da) Claudin-18.2-specifikke immunoreceptorer og t-celleepitoper
MA45051A (fr) Polynucléotides codant la relaxine
CL2017000119S1 (es) Llanta.
DK3440206T3 (da) Multimer-kodende nukleinsyre og anvendelser deraf
DK3433280T3 (da) Protease-aktiverede T-celle-bispecifikke molekyler
DK3067559T3 (da) Inflator
DK3205564T3 (da) Ladcykel
CY1120997T1 (el) Πρωτεϊνες συντηξης uti
DK3451821T3 (da) Patron til pattekop og pattekop omfattende patronen
EP3522877A4 (en) SMALL MOLECULAR AMPK ACTIVATORS
ITUA20161494A1 (it) Procedimento per controllare sorgenti di illuminazione, sistema e prodotto informatico corrispondenti
DK3524099T3 (da) Oppusteligt produkt
FR3048781B1 (fr) Accelerometre lineaire amorti
DK3412591T3 (da) Inderhætte-fastgørelses-løsgørelsesstruktur, og beholder udstyret dermed
MA53963A (fr) Système de carreaux à usages multiples
DK3482210T3 (da) Assay til detektering af totalt og s129-phosphoryleret alpha-synuklein
MA42671A (fr) Brouette à déversement latéral
FR3053003B1 (fr) Pneumatique cloute