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CR8932A - Composicion de anticuerpo her2 - Google Patents

Composicion de anticuerpo her2

Info

Publication number
CR8932A
CR8932A CR8932A CR8932A CR8932A CR 8932 A CR8932 A CR 8932A CR 8932 A CR8932 A CR 8932A CR 8932 A CR8932 A CR 8932A CR 8932 A CR8932 A CR 8932A
Authority
CR
Costa Rica
Prior art keywords
her2 antibody
composition
antibody composition
her2
binds
Prior art date
Application number
CR8932A
Other languages
English (en)
Inventor
Yung-Hsiang Kao
Martin Vanderlaan
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CR8932A publication Critical patent/CR8932A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describe una composicion que comprende una especie principal de anticuerpo HER2 que se une al dominio II de HER2, y una variante de una secuencia de aminoacido del mismo que comprende una extension lider aminoterminal. Tambien se describen formulaciones farmaceuticas que comprenden la composicion, y usos terapeuticos para la composicion.
CR8932A 2004-07-22 2007-02-16 Composicion de anticuerpo her2 CR8932A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59020204P 2004-07-22 2004-07-22

Publications (1)

Publication Number Publication Date
CR8932A true CR8932A (es) 2008-04-25

Family

ID=36090425

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8932A CR8932A (es) 2004-07-22 2007-02-16 Composicion de anticuerpo her2

Country Status (37)

Country Link
US (3) US7560111B2 (es)
EP (1) EP1771482B1 (es)
JP (7) JP2008507520A (es)
KR (14) KR20150140417A (es)
CN (1) CN101023100B (es)
AR (2) AR050353A1 (es)
AU (1) AU2005287404B2 (es)
BR (1) BRPI0513681A (es)
CA (1) CA2574821C (es)
CO (1) CO5720212A1 (es)
CR (1) CR8932A (es)
DK (1) DK1771482T3 (es)
EC (1) ECSP077261A (es)
ES (1) ES2521140T3 (es)
GT (1) GT200500199A (es)
HK (1) HK1102599A1 (es)
HR (1) HRP20141111T1 (es)
IL (1) IL180608A0 (es)
JO (1) JO2984B1 (es)
MA (1) MA28784B1 (es)
MX (1) MX2007000723A (es)
MY (1) MY169272A (es)
NO (1) NO341293B1 (es)
NZ (1) NZ552580A (es)
PA (1) PA8639701A1 (es)
PE (1) PE20060552A1 (es)
PL (1) PL1771482T3 (es)
PT (1) PT1771482E (es)
RS (1) RS53594B1 (es)
RU (1) RU2361880C2 (es)
SI (1) SI1771482T1 (es)
SV (1) SV2006002174A (es)
TN (1) TNSN07020A1 (es)
TW (1) TWI369992B (es)
UA (1) UA90480C2 (es)
WO (1) WO2006033700A2 (es)
ZA (1) ZA200701234B (es)

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