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CR20140053A - DEOXICOLIC ACID FORMULATIONS AND SALTS OF THE SAME - Google Patents

DEOXICOLIC ACID FORMULATIONS AND SALTS OF THE SAME

Info

Publication number
CR20140053A
CR20140053A CR20140053A CR20140053A CR20140053A CR 20140053 A CR20140053 A CR 20140053A CR 20140053 A CR20140053 A CR 20140053A CR 20140053 A CR20140053 A CR 20140053A CR 20140053 A CR20140053 A CR 20140053A
Authority
CR
Costa Rica
Prior art keywords
deoxicolic
salts
same
acid formulations
formulations
Prior art date
Application number
CR20140053A
Other languages
Spanish (es)
Inventor
Robert Emil Hodge
Jeffrey Douglas Webster
Robert M Moriarty
Original Assignee
Kythera Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45569726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20140053(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kythera Biopharmaceuticals Inc filed Critical Kythera Biopharmaceuticals Inc
Publication of CR20140053A publication Critical patent/CR20140053A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica acuosa que comprende desde aproximadamente 0.4% en p/v a menos de aproximadamente 2% en p/v de una sal de ácido desoxicólico, en donde la composición se mantiene a un pH desde aproximadamentThe present invention relates to an aqueous pharmaceutical composition comprising from about 0.4% in w / v to less than about 2% in w / v of a deoxycholic acid salt, wherein the composition is maintained at a pH from approximately

CR20140053A 2011-08-23 2014-01-30 DEOXICOLIC ACID FORMULATIONS AND SALTS OF THE SAME CR20140053A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/048806 WO2013028177A1 (en) 2011-08-23 2011-08-23 Formulations of deoxycholic acid and salts thereof

Publications (1)

Publication Number Publication Date
CR20140053A true CR20140053A (en) 2014-06-12

Family

ID=45569726

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20140053A CR20140053A (en) 2011-08-23 2014-01-30 DEOXICOLIC ACID FORMULATIONS AND SALTS OF THE SAME

Country Status (18)

Country Link
JP (1) JP5919597B2 (en)
KR (5) KR102073536B1 (en)
CN (3) CN108619089A (en)
AU (3) AU2011375432B2 (en)
BR (1) BR112014000547B1 (en)
CA (1) CA2842177C (en)
CR (1) CR20140053A (en)
EA (1) EA029305B1 (en)
IL (1) IL230547A (en)
IN (1) IN2014CN02188A (en)
MX (1) MX350390B (en)
MY (1) MY184277A (en)
NZ (1) NZ620040A (en)
PH (1) PH12016501175A1 (en)
SG (1) SG2014013205A (en)
UA (1) UA113522C2 (en)
WO (1) WO2013028177A1 (en)
ZA (1) ZA201401027B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
KR20180100309A (en) * 2015-11-04 2018-09-10 키쎄라 바이오파마슈티컬즈 인코포레이티드 Methods for the treatment of accumulated fats using deoxycholic acid and its salts
US20180078621A1 (en) * 2016-09-22 2018-03-22 Kyoung Lack Lee Composition for hypotonic lipolysis and manufacturing method thereof
KR101841193B1 (en) * 2016-09-22 2018-03-22 이경락 Composition for hypotonic lipolysis and manufacturing method thereof
US20190314388A1 (en) * 2018-04-16 2019-10-17 Penmix Ltd. Pharmaceutical composition containing deoxycholic acid
KR102172439B1 (en) * 2018-12-05 2020-10-30 송미희 Composition for lipolysis and injection composition comprising the same
KR102064864B1 (en) 2019-02-08 2020-01-10 (주)제테마 Topical injectable composition
KR102111346B1 (en) * 2019-08-20 2020-05-22 아영창 Aqueous composition with sodium deoxycholate having improved stability against precipitation
KR20220026068A (en) 2020-08-25 2022-03-04 강명범 Composition for lipolysis and injection composition comprising the same
CN116617160A (en) * 2023-07-25 2023-08-22 山东则正医药技术有限公司 Aqueous suspension, preparation method, freeze-dried powder, application and fat reduction injection
CN118005707A (en) * 2024-01-18 2024-05-10 山东省食品药品检验研究院 Sodium deoxycholate crystal form A and preparation method and application thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754709B1 (en) 1996-10-23 1999-03-05 Sanofi Sa COSMETIC COMPOSITION CONTAINING AN ANTAGONIST OF GAMMA NEUROPEPTIDE RECEPTORS AND ALPHA 2 ANTAGONISTS THAT MAY BE INCORPORATED IN SUCH A COMPOSITION
JP4790123B2 (en) * 1998-07-24 2011-10-12 ヨー、セオ、ホン Dispensing clear aqueous solution with bile acid
US6417179B1 (en) 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
DE10361067A1 (en) * 2003-12-22 2005-07-14 Aventis Pharma Deutschland Gmbh Medicinal lipolysis of fat accumulations
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
SI2422789T1 (en) * 2004-05-19 2018-07-31 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Injectable coposition comprising sodium deoxycholate
US7754230B2 (en) 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
AU2006255097B2 (en) 2005-06-06 2012-02-09 Georgetown University Compositions and methods for lipo modeling
TW201011755A (en) 2008-09-10 2010-03-16 Skymedi Corp Flash memory system and its data recovery method
JP5420946B2 (en) * 2009-03-23 2014-02-19 富士フイルム株式会社 Minoxidil aqueous composition containing bile acids
EP2645099A1 (en) 2012-03-30 2013-10-02 Phares Pharmaceutical Research N.V. Biorelevant compositions

Also Published As

Publication number Publication date
CN108619089A (en) 2018-10-09
AU2011375432B2 (en) 2016-02-04
MX350390B (en) 2017-09-06
KR20170075016A (en) 2017-06-30
KR102034606B1 (en) 2019-10-22
PH12016501175B1 (en) 2017-12-11
KR20190119677A (en) 2019-10-22
CA2842177C (en) 2016-07-19
AU2016202661B2 (en) 2018-02-22
SG2014013205A (en) 2014-05-29
JP5919597B2 (en) 2016-05-18
KR101919269B1 (en) 2018-11-15
CN108743522A (en) 2018-11-06
IN2014CN02188A (en) 2015-05-29
AU2018202807A1 (en) 2018-05-10
CN103826608A (en) 2014-05-28
AU2018202807B2 (en) 2020-01-16
BR112014000547A2 (en) 2017-02-14
WO2013028177A1 (en) 2013-02-28
KR20200013103A (en) 2020-02-05
UA113522C2 (en) 2017-02-10
JP2014524467A (en) 2014-09-22
PH12016501175A1 (en) 2017-12-11
MX2014001495A (en) 2014-04-25
MY184277A (en) 2021-03-30
KR101751585B1 (en) 2017-06-27
NZ620040A (en) 2016-06-24
KR20180123734A (en) 2018-11-19
KR102073536B1 (en) 2020-02-04
ZA201401027B (en) 2017-09-27
IL230547A (en) 2017-02-28
AU2011375432A1 (en) 2014-02-06
IL230547A0 (en) 2014-03-31
KR20150000448A (en) 2015-01-02
BR112014000547B1 (en) 2021-11-09
AU2016202661A1 (en) 2016-05-19
EA201490175A1 (en) 2014-06-30
CA2842177A1 (en) 2013-02-28
EA029305B1 (en) 2018-03-30

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