CO5070571A1 - Preparado farmaceutico de moxifloxacina - Google Patents
Preparado farmaceutico de moxifloxacinaInfo
- Publication number
- CO5070571A1 CO5070571A1 CO99070667A CO99070667A CO5070571A1 CO 5070571 A1 CO5070571 A1 CO 5070571A1 CO 99070667 A CO99070667 A CO 99070667A CO 99070667 A CO99070667 A CO 99070667A CO 5070571 A1 CO5070571 A1 CO 5070571A1
- Authority
- CO
- Colombia
- Prior art keywords
- oral administration
- preparation
- pharmaceutical preparation
- pharmaceutical
- administration according
- Prior art date
Links
- FABPRXSRWADJSP-MEDUHNTESA-N moxifloxacin Chemical compound COC1=C(N2C[C@H]3NCCC[C@H]3C2)C(F)=CC(C(C(C(O)=O)=C2)=O)=C1N2C1CC1 FABPRXSRWADJSP-MEDUHNTESA-N 0.000 title abstract 3
- 229960003702 moxifloxacin Drugs 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 5
- 239000002706 dry binder Substances 0.000 abstract 2
- 239000000314 lubricant Substances 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical group [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229920002785 Croscarmellose sodium Polymers 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 229960001681 croscarmellose sodium Drugs 0.000 abstract 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Preparado farmacéutico para la administración oral que contienemoxifloxacina o una sal y/o hidrato de la misma,al menos un aglutinante en seco,al menos un coadyuvante de disgregación, yal menos un agente lubricante,caracterizado porque el preparado contiene del 2,5%al 25% de lactosa. Preparado farmacéutico para la administración oral según la reivindicación 1, caracterizado porque el preparado contiene, referido a una dosificación individual, de 50 a 800 mg de moxifloxacina o de sus sales y/o hidratos. Preparado farmacéutico para la administración oral según la reivindicación 1 ó 2, caracterizado porque el aglutinante en seco es celulosa microcristalina. Preparado farmacéutico para la administración oral según una de las reivindicaciones 1 a 3, caracterizado porque el coadyuvante de disgregación es croscarmelosa sódica. Preparado farmacéutico para la administración oral según una cualquiera de las reivindicaciones 1 a 4, caracterizado porque el agente lubricante es estearato de magnesio.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19855758 | 1998-11-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5070571A1 true CO5070571A1 (es) | 2001-08-28 |
Family
ID=7889824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO99070667A CO5070571A1 (es) | 1998-11-10 | 1999-11-09 | Preparado farmaceutico de moxifloxacina |
Country Status (41)
| Country | Link |
|---|---|
| US (1) | US6610327B1 (es) |
| EP (1) | EP1128831B1 (es) |
| JP (1) | JP4809978B2 (es) |
| KR (1) | KR100650489B1 (es) |
| CN (1) | CN1149993C (es) |
| AR (1) | AR021074A1 (es) |
| AT (1) | ATE279193T1 (es) |
| AU (1) | AU745282B2 (es) |
| BG (1) | BG64974B1 (es) |
| BR (2) | BR9915208A (es) |
| CA (1) | CA2349161C (es) |
| CO (1) | CO5070571A1 (es) |
| CU (1) | CU23260B7 (es) |
| CZ (1) | CZ292069B6 (es) |
| DE (1) | DE59910858D1 (es) |
| DK (1) | DK1128831T3 (es) |
| EE (1) | EE04418B1 (es) |
| ES (1) | ES2229786T3 (es) |
| HK (1) | HK1042245B (es) |
| HN (1) | HN1999000183A (es) |
| HR (1) | HRP20010332B1 (es) |
| HU (1) | HU229065B1 (es) |
| ID (1) | ID29089A (es) |
| IL (2) | IL142642A0 (es) |
| MA (1) | MA26757A1 (es) |
| MY (1) | MY121114A (es) |
| NO (1) | NO319342B1 (es) |
| NZ (1) | NZ511554A (es) |
| PE (1) | PE20001304A1 (es) |
| PL (1) | PL194020B1 (es) |
| PT (1) | PT1128831E (es) |
| RU (1) | RU2230555C9 (es) |
| SI (1) | SI1128831T1 (es) |
| SK (1) | SK283936B6 (es) |
| SV (1) | SV1999000194A (es) |
| TR (1) | TR200101310T2 (es) |
| TW (1) | TW580388B (es) |
| UA (1) | UA72483C2 (es) |
| UY (1) | UY25792A1 (es) |
| WO (1) | WO2000027398A1 (es) |
| ZA (1) | ZA200103141B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19937116A1 (de) * | 1999-08-06 | 2001-02-08 | Bayer Ag | Moxifloxacin Kochsalzformulierung |
| GB0209265D0 (en) | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| EP1663226A1 (en) * | 2003-09-03 | 2006-06-07 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of moxifloxacin and processes for their preparation |
| WO2006015545A1 (fr) * | 2004-08-11 | 2006-02-16 | Shenzhen Tys R & D Co., Ltd. | Capsule de gelatine de moxifloxacin et procede pour sa preparation |
| CN1330306C (zh) * | 2004-08-11 | 2007-08-08 | 深圳市天一时科技开发有限公司 | 莫西沙星明胶胶囊剂及其制备方法 |
| CN100363001C (zh) * | 2005-09-21 | 2008-01-23 | 深圳市天一时科技开发有限公司 | 一种莫西沙星胶囊剂及其制备方法 |
| WO2007033515A1 (fr) * | 2005-09-21 | 2007-03-29 | Shenzhen Tys R & D Co., Ltd. | Formulation orale contenant de la moxifloxacine et son procédé de préparation |
| WO2007033522A1 (fr) * | 2005-09-21 | 2007-03-29 | Shenzhen Tys R & D Co., Ltd. | Formulation de gélule contenant de la moxifloxacine et son procédé de préparation |
| US8314122B2 (en) * | 2008-10-09 | 2012-11-20 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Using of organic solvents in wet granulation of moxifloxacin |
| US20110293717A1 (en) | 2008-12-08 | 2011-12-01 | Ratiopharm Gmbh | Compacted moxifloxacin |
| TR200907227A2 (tr) * | 2009-09-18 | 2011-04-21 | Bi̇lgi̇ç Mahmut | Çözünürlüğü yüksek stabil mikronize granüller. |
| CN101890169B (zh) * | 2009-11-16 | 2013-09-11 | 江苏亚邦强生药业有限公司 | 莫西沙星口服制剂及其制备方法 |
| WO2011086577A2 (en) * | 2010-01-12 | 2011-07-21 | Msn Laboratories Limited | Pharmaceutical composition of moxifloxacin and its pharmaceutically acceptable salts |
| CN102247313A (zh) * | 2010-06-11 | 2011-11-23 | 北京润德康医药技术有限公司 | 一种以莫西沙星为活性成分的口服缓释固体制剂 |
| CN102247314A (zh) * | 2011-01-12 | 2011-11-23 | 北京润德康医药技术有限公司 | 一种以莫西沙星为活性成分的口服固体制剂 |
| EP2510929A1 (en) * | 2011-04-11 | 2012-10-17 | Innocoll Technologies Limited | Methods for treating bacterial infection |
| MX2011004759A (es) | 2011-05-04 | 2012-11-21 | Senosiain S A De C V Lab | Nuevas formas solidas de antibioticos. |
| RU2466718C1 (ru) * | 2011-10-14 | 2012-11-20 | Закрытое акционерное общество "Брынцалов-А" | Фармацевтический препарат моксифлоксацина |
| US9675582B2 (en) | 2011-10-25 | 2017-06-13 | U.S. Phytotherapy, Inc. | Alternative ACT with natural botanical active GRAS ingredients for treatment and prevention of the Zika virus |
| WO2013063271A1 (en) * | 2011-10-25 | 2013-05-02 | U.S. Phytotherapy, Inc. | Artemisinin and berberine compositions and methods of making |
| CA2853701A1 (en) | 2011-10-25 | 2013-05-02 | U.S. Phytotherapy, Inc. | Artemisinin and berberine compositions and methods of making |
| US9358261B2 (en) | 2011-10-25 | 2016-06-07 | U.S. Phytotherapy, Inc. | Additional artemisinin and berberine compositions and methods of making |
| BR112014012994A2 (pt) * | 2011-11-30 | 2017-06-13 | Toyama Chemical Co Ltd | tablete contendo hidrato de metanossulfonato do ácido 1-ciclopropil-8-(difluorometóxi)-7-[(1r)-1-metil-2,3-diidro-1h-isoindol-5-il]-4-oxo-1, 4-diidroquinolina-3-carboxílico |
| BRPI1106900A2 (pt) | 2011-12-26 | 2013-11-05 | Ems Sa | Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção |
| CN102525982A (zh) * | 2012-02-21 | 2012-07-04 | 天津市汉康医药生物技术有限公司 | 一种稳定的盐酸莫西沙星药物组合物 |
| CN102600093B (zh) * | 2012-04-11 | 2013-06-05 | 南京优科生物医药有限公司 | 一种莫西沙星片剂及其制备方法 |
| FR2992218B1 (fr) | 2012-06-22 | 2015-01-23 | Rivopharm Sa | Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation |
| CN103768063B (zh) * | 2012-10-19 | 2016-04-20 | 深圳信立泰药业股份有限公司 | 一种盐酸莫西沙星药物组合物及其制备方法 |
| RU2561037C2 (ru) * | 2013-02-07 | 2015-08-20 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Антибактериальная фармацевтическая композиция и способ ее получения |
| WO2015093669A1 (ko) * | 2013-12-20 | 2015-06-25 | 씨제이헬스케어 주식회사 | 목시플록사신 수성 제형 및 이의 제조방법 |
| RU2558932C1 (ru) * | 2014-05-22 | 2015-08-10 | Открытое Акционерное Общество "Татхимфармпрепараты" | Фармацевтическая композиция моксифлоксацина и способ ее приготовления |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3601566A1 (de) * | 1986-01-21 | 1987-07-23 | Bayer Ag | Pharmazeutische zubereitungen von ciprofloxacin |
| US5286754A (en) | 1986-01-21 | 1994-02-15 | Bayer Aktiengesellschaft | Pharmaceutical formulations of ciprofloxacin |
| JPH01175936A (ja) * | 1987-12-28 | 1989-07-12 | Kyorin Pharmaceut Co Ltd | ６．８−ジフルオロ−１−（２−フルオロエチル）−１，４−ジヒドロ−７−（４−メチル−１−ピペラジニル）−４−オキソ−３−キノリンカルボン酸を有効成分とする錠剤 |
| DE3906365A1 (de) | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| TW209865B (es) * | 1992-01-10 | 1993-07-21 | Bayer Ag | |
| DE19546249A1 (de) * | 1995-12-12 | 1997-06-19 | Bayer Ag | Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| PA8466701A1 (es) * | 1998-01-21 | 2000-09-29 | Pfizer Prod Inc | Comprimido de mesilato de trovafloxacino |
-
1999
- 1999-10-29 UA UA2001063872A patent/UA72483C2/uk unknown
- 1999-10-29 NZ NZ511554A patent/NZ511554A/en not_active IP Right Cessation
- 1999-10-29 KR KR1020017005833A patent/KR100650489B1/ko active IP Right Grant
- 1999-10-29 BR BR9915208-8A patent/BR9915208A/pt not_active IP Right Cessation
- 1999-10-29 ID IDW00200101040A patent/ID29089A/id unknown
- 1999-10-29 AU AU12674/00A patent/AU745282B2/en not_active Expired
- 1999-10-29 JP JP2000580627A patent/JP4809978B2/ja not_active Expired - Lifetime
- 1999-10-29 PL PL99348112A patent/PL194020B1/pl unknown
- 1999-10-29 IL IL14264299A patent/IL142642A0/xx active IP Right Grant
- 1999-10-29 BR BRPI9915208-8 patent/BRPI9915208B8/pt unknown
- 1999-10-29 CN CNB998131245A patent/CN1149993C/zh not_active Expired - Lifetime
- 1999-10-29 AT AT99955906T patent/ATE279193T1/de active
- 1999-10-29 CZ CZ20011652A patent/CZ292069B6/cs not_active IP Right Cessation
- 1999-10-29 ES ES99955906T patent/ES2229786T3/es not_active Expired - Lifetime
- 1999-10-29 US US09/830,770 patent/US6610327B1/en not_active Expired - Lifetime
- 1999-10-29 PT PT99955906T patent/PT1128831E/pt unknown
- 1999-10-29 HU HU0104762A patent/HU229065B1/hu unknown
- 1999-10-29 SI SI9930706T patent/SI1128831T1/xx unknown
- 1999-10-29 TR TR2001/01310T patent/TR200101310T2/xx unknown
- 1999-10-29 SK SK610-2001A patent/SK283936B6/sk not_active IP Right Cessation
- 1999-10-29 DE DE1999510858 patent/DE59910858D1/de not_active Expired - Lifetime
- 1999-10-29 CA CA002349161A patent/CA2349161C/en not_active Expired - Lifetime
- 1999-10-29 EP EP99955906A patent/EP1128831B1/de not_active Expired - Lifetime
- 1999-10-29 EE EEP200100259A patent/EE04418B1/xx unknown
- 1999-10-29 RU RU2001116096/15A patent/RU2230555C9/ru active
- 1999-10-29 DK DK99955906T patent/DK1128831T3/da active
- 1999-10-29 WO PCT/EP1999/008230 patent/WO2000027398A1/de active IP Right Grant
- 1999-11-01 HN HN1999000183A patent/HN1999000183A/es unknown
- 1999-11-03 AR ARP990105567A patent/AR021074A1/es active IP Right Grant
- 1999-11-04 TW TW088119183A patent/TW580388B/zh not_active IP Right Cessation
- 1999-11-05 MY MYPI99004825A patent/MY121114A/en unknown
- 1999-11-08 UY UY25792A patent/UY25792A1/es not_active Application Discontinuation
- 1999-11-09 CO CO99070667A patent/CO5070571A1/es unknown
- 1999-11-09 PE PE1999001134A patent/PE20001304A1/es not_active IP Right Cessation
- 1999-11-10 SV SV1999000194A patent/SV1999000194A/es active IP Right Grant
-
2001
- 2001-04-17 IL IL142642A patent/IL142642A/en not_active IP Right Cessation
- 2001-04-18 ZA ZA200103141A patent/ZA200103141B/en unknown
- 2001-04-20 BG BG105459A patent/BG64974B1/bg unknown
- 2001-05-07 NO NO20012248A patent/NO319342B1/no not_active IP Right Cessation
- 2001-05-10 CU CU20010114A patent/CU23260B7/es unknown
- 2001-05-10 MA MA26189A patent/MA26757A1/fr unknown
- 2001-05-10 HR HR20010332A patent/HRP20010332B1/xx not_active IP Right Cessation
-
2002
- 2002-05-29 HK HK02104010.6A patent/HK1042245B/zh not_active IP Right Cessation
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