CN113197973A - Pharmaceutical composition and preparation method thereof - Google Patents
Pharmaceutical composition and preparation method thereof Download PDFInfo
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- CN113197973A CN113197973A CN202110505544.3A CN202110505544A CN113197973A CN 113197973 A CN113197973 A CN 113197973A CN 202110505544 A CN202110505544 A CN 202110505544A CN 113197973 A CN113197973 A CN 113197973A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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Abstract
The invention provides a pharmaceutical composition and a preparation method thereof, relating to the technical field of traditional Chinese medicines. The pharmaceutical composition of the invention is composed of 45-90 parts by weight of bletilla striata, 40-75 parts by weight of angelica dahurica, 30-85 parts by weight of frankincense, 15-65 parts by weight of myrrh and 35-80 parts by weight of sanguisorba officinalis carbon. The pharmaceutical composition disclosed by the invention is simple in component, has a good treatment effect on burns and scalds and wounds of diabetics, and is quick in effect and short in healing period.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to an external traditional Chinese medicine composition and a preparation method thereof.
Background
Four problems of wound surface pain, progressive necrosis, susceptibility to infection and difficult scar healing exist in the treatment of the burns and scalds. The traditional Chinese medicine has a long history and obvious effect on treating burns and scalds, wherein the traditional Chinese medicine for treating burns and scalds is prepared from the following traditional Chinese medicine formulations: oils such as arnebia oil; ointments such as burn ointments; powder is burned by a person; pellicle such as burn medicine; drops such as convalescent drops; sprays such as burn sprays; cream such as compound aloe cream; film formation such as white-trap coating film.
The traditional Chinese medicine formula burn and scald medicament at present is relatively complex in composition, has a good burn and scald treatment effect, is long in effect taking time and long in wound healing period, and has certain use contraindications on low immunocompetence and sensitive skin.
Disclosure of Invention
In view of the above, the invention provides the traditional Chinese medicine composition for treating burns and scalds, which has a remarkable effect and can be used by different people, and the composition can be used for treating burns and scalds and has a good curative effect on various traumas, wounds, red wounds, diabetic wounds, knife wounds and the like.
The pharmaceutical composition is processed by adopting five Chinese herbal medicines as raw materials, and specifically comprises bletilla striata, angelica dahurica, frankincense, myrrh and garden burnet root.
Wherein rhizoma Bletillae has effects of promoting blood circulation, stopping bleeding, relieving swelling, and promoting granulation. In clinic, bletilla striata is mainly used for stopping bleeding and activating blood circulation, on one hand, blood stasis which is formed can be removed, and on the other hand, bletilla striata has a very good hemostatic effect on bleeding. Besides, bletilla has the functions of detumescence and tissue regeneration. Bletilla striata is a sweet and warm Chinese herbal medicine, and the manifestation of excessive internal heat is easy to appear after long-term use.
The angelica dahurica is pungent and warm in nature and has the effects of relieving exterior syndrome and cold, dispelling wind and relieving pain, freeing nasal orifices, eliminating dampness and stopping leucorrhea, and reducing swelling and expelling pus, and can be clinically used for treating cold headache, supra-orbital bone pain, nasal obstruction and rhinorrhea, nasosinusitis, toothache, leukorrhagia, sore and carbuncle swelling and pain of women and the like. Modern pharmacological research shows that the angelica dahurica has the effects of relieving fever and pain, resisting inflammation, inhibiting pathogenic microorganisms, resisting oxidation, resisting tumors and the like.
Ru Xiang is warm in nature, pungent and bitter in flavor. Has effects in regulating qi, promoting blood circulation, relieving pain, eliminating swelling, and promoting granulation. Boswellia belongs to the blood-activating and pain-relieving herbs classified under blood-activating and stasis-resolving herbs.
It is bitter and mild in flavor. Has the effects of removing blood stasis, relieving pain, and promoting the subsidence of swelling and granulation. Can be used for treating traumatic injury, blood stasis, swelling and pain, carbuncle, cellulitis, pain of chest and abdomen, and non-convergence of sore.
Sanguisorba officinalis is bitter and sour in nature and cool in nature, and has the effects of cooling blood, stopping bleeding, purging fire and healing sores.
The pharmaceutical composition is prepared from the following Chinese herbal medicines in parts by weight:
45-90 parts of bletilla striata,
40-75 parts of radix angelicae dahuricae,
30-85 parts of frankincense,
15-65 parts of myrrh
35-80 parts of garden burnet carbon.
Another object of the present invention is to provide a method for preparing the pharmaceutical composition, comprising the steps of:
1) sun drying rhizoma Bletillae, radix Angelicae Dahuricae, Olibanum, Myrrha, and radix Sangusorbae carbon;
2) weighing the dried Chinese herbal medicine raw materials according to a proportion, mixing and crushing;
3) sieving the crushed Chinese herbal medicines to obtain the medicinal composition.
Preferably, in the step 3) of the invention, the crushed Chinese herbal medicines are processed by a Chinese pharmacopoeia No. three, No. four or No. five sieve to obtain the pharmaceutical composition.
The pharmaceutical composition can be used as an external medicament for treating burns, scalds and knife wounds.
Compared with the prior art, the invention has the following beneficial effects:
1) the burn and scald medicament has simple composition, only comprises five Chinese herbal medicines, and reduces the stimulation effect of the toxicity of the medicament on the affected part;
2) the pharmaceutical composition can be used for diabetics, and does not have side effects;
3) the medicine composition of the present invention has fast acting and short healing period.
Drawings
FIG. 1 is a view of the affected part of case 1 where a scald occurred for 10 days without using the pharmaceutical composition of the present invention;
FIG. 2 is a view showing the state of the affected part of the patient in case 1 after 24 hours of application of the pharmaceutical composition of the present invention;
FIG. 3 is a state of the affected part of the patient in case 1 after being coated with the pharmaceutical composition of the present invention for 5 days;
fig. 4 is a view showing the state of the affected part of the patient in case 1 after 12 days of application of the pharmaceutical composition of the present invention.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
The pharmaceutical composition is prepared by the following steps:
1) sun drying rhizoma Bletillae, radix Angelicae Dahuricae, Olibanum, Myrrha, and radix Sangusorbae carbon;
2) weighing 60 parts by weight of aired bletilla striata, 50 parts by weight of angelica dahurica, 45 parts by weight of frankincense, 35 parts by weight of myrrh and 55 parts by weight of garden burnet carbon, uniformly mixing and crushing;
3) sieving the crushed Chinese herbal medicine powder by using a sieve of Chinese pharmacopoeia No. three to obtain the medicinal composition.
Example 2
The pharmaceutical composition is prepared by the following steps:
1) sun drying rhizoma Bletillae, radix Angelicae Dahuricae, Olibanum, Myrrha, and radix Sangusorbae carbon;
2) weighing 60 parts by weight of aired bletilla striata, 75 parts by weight of angelica dahurica, 40 parts by weight of frankincense, 20 parts by weight of myrrh and 50 parts by weight of garden burnet carbon, uniformly mixing and crushing;
3) sieving the crushed Chinese herbal medicine powder by using a sieve of Chinese pharmacopoeia No. four to obtain the medicinal composition.
Example 3
The pharmaceutical composition is prepared by the following steps:
1) sun drying rhizoma Bletillae, radix Angelicae Dahuricae, Olibanum, Myrrha, and radix Sangusorbae carbon;
2) weighing 90 parts by weight of aired bletilla striata, 40 parts by weight of angelica dahurica, 80 parts by weight of frankincense, 25 parts by weight of myrrh and 70 parts by weight of garden burnet carbon, uniformly mixing and crushing;
3) sieving the crushed Chinese herbal medicine powder by adopting a sieve of Chinese pharmacopoeia No. nine to obtain the pharmaceutical composition.
Example 4
The pharmaceutical composition is prepared by the following steps:
1) sun drying rhizoma Bletillae, radix Angelicae Dahuricae, Olibanum, Myrrha, and radix Sangusorbae carbon;
2) weighing 80 parts by weight of aired bletilla striata, 75 parts by weight of angelica dahurica, 85 parts by weight of frankincense, 15 parts by weight of myrrh and 35 parts by weight of garden burnet carbon, uniformly mixing and crushing;
3) sieving the crushed Chinese herbal medicine powder by using a sieve of Chinese pharmacopoeia No. five, thus obtaining the pharmaceutical composition of the invention.
Example 5
The pharmaceutical composition is prepared by the following steps:
1) sun drying rhizoma Bletillae, radix Angelicae Dahuricae, Olibanum, Myrrha, and radix Sangusorbae carbon;
2) weighing 45 parts of aired bletilla striata, 50 parts of angelica dahurica, 60 parts of frankincense, 30 parts of myrrh and 50 parts of garden burnet carbon, uniformly mixing and crushing;
3) sieving the crushed Chinese herbal medicine powder by using a sieve of Chinese pharmacopoeia No. three to obtain the medicinal composition.
Application case
Case 1
Zhao somewhere mountain, man, 50 years old, diabetic, Hebei province Baoding City Qicun county, Hebei province, Seixing county, Bei village, were seriously scalded by boiled water 8 month 13 days in 2020, and after 10 days of treatment in a certain scalding hospital in this county, the wound appeared to be infected, as shown in figure 1. After 8 months and 23 days, the pharmaceutical composition of the embodiment 1 of the invention is externally applied, the wound starts to heal and scab after 24 hours, the wound continuously scabs after 5 days, the scab is removed after 12 days, pores are recovered, and the wound is completely recovered without scars.
Case 2
Ten days after male severe scald due to Deng in Dang, the pharmaceutical composition of example 2 of the present invention is used, and the wound starts to heal after 24 hours, scabs after 36 hours, and heals after about ten days.
Case 3
Wangzhi, male, Sinkiang Wulu wood man, has no fruit after being treated by a plurality of hospitals due to high-temperature scald, and has serious infection after 35 days of scald, namely, the wound starts to heal and scab after 36 hours after the external application of the pharmaceutical composition of the embodiment 2 of the invention is started, and the scab falls off automatically after two weeks, so that the wound is healed without hyperplasia scars.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (4)
1. The pharmaceutical composition is characterized by comprising the following Chinese herbal medicines in parts by weight:
45-90 parts of bletilla striata,
40-75 parts of radix angelicae dahuricae,
30-85 parts of frankincense,
15-65 parts of myrrh
35-80 parts of garden burnet carbon.
2. A process for the preparation of a pharmaceutical composition according to claim 1, comprising the steps of:
1) sun drying rhizoma Bletillae, radix Angelicae Dahuricae, Olibanum, Myrrha, and radix Sangusorbae carbon;
2) weighing the dried Chinese herbal medicine raw materials according to a proportion, mixing and crushing;
3) sieving the crushed Chinese herbal medicines to obtain the medicinal composition.
3. The preparation method according to claim 2, wherein the step 3) is to sieve the pulverized herbs by using a sieve of Chinese pharmacopoeia No. three, No. four or No. five to obtain the pharmaceutical composition.
4. The use of the pharmaceutical composition according to claim 1, wherein the pharmaceutical composition is used as an external medicament for treating burns, scalds and knife wounds.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110505544.3A CN113197973A (en) | 2021-05-10 | 2021-05-10 | Pharmaceutical composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110505544.3A CN113197973A (en) | 2021-05-10 | 2021-05-10 | Pharmaceutical composition and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113197973A true CN113197973A (en) | 2021-08-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110505544.3A Withdrawn CN113197973A (en) | 2021-05-10 | 2021-05-10 | Pharmaceutical composition and preparation method thereof |
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| Country | Link |
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| CN (1) | CN113197973A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116350716A (en) * | 2023-04-14 | 2023-06-30 | 河北八玺生物科技有限公司 | External powder for treating wounds, burns and scalds and preparation method thereof |
-
2021
- 2021-05-10 CN CN202110505544.3A patent/CN113197973A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116350716A (en) * | 2023-04-14 | 2023-06-30 | 河北八玺生物科技有限公司 | External powder for treating wounds, burns and scalds and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
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| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20210803 |