CN103520842B - THz wave medical instrument - Google Patents
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- CN103520842B CN103520842B CN201310526355.XA CN201310526355A CN103520842B CN 103520842 B CN103520842 B CN 103520842B CN 201310526355 A CN201310526355 A CN 201310526355A CN 103520842 B CN103520842 B CN 103520842B
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Abstract
The invention provides a kind of THz wave medical instrument comprise probe and pop one's head in for driving and process the controller of the Information Monitoring that probe inputs, described probe comprises for there is the THz wave generator of THz wave and the acquisition electrode for carrying out electrocardiogram acquisition.THz wave medical instrument provided by the invention, not only can carry out the treatment of cardiovascular disease to user, can also carry out electrocardiogram acquisition and also analyze the ecg information collected, thus reach the object of diagnosis to user.Meanwhile, the probe of THz wave medical instrument in the predetermined treatment of human body or diagnosis position by its sucker suction, carries out hand-held without the need to people, is convenient to user and operates.And THz wave medical instrument also has use advantage simple, easy to carry.
Description
Technical field
The present invention relates to armarium, particularly relate to a kind of Terahertz therapeutic instrument.
Background technology
Along with the Rapid Variable Design of China's age composition in the population, China enters aging society in advance, simultaneously cardiovascular disease incidence and mortality rate sustainable growth, and cardiovascular burden, becomes important public hygiene problem.Strengthen preventing and treating cardiovascular disease very urgent, a lot of hypertensive patient is in order to prevent and treat great unexpected generation, have to adopt the therapeutic modality of taking medicine all the life, but the therapeutic modality of taking medicine all the life also with the generation of a lot of side effect, can bring very major injury to human body itself.
1998, three American scientists Furchgott, Ignarro and FeridMurad have been awarded in Nobel physiology's prize, find that nitric oxide (NO) molecule is that body weight for humans wants messenger substances to commend them, a kind ofly in body act on extensive and unique signaling molecule, communication for information between neurocyte and transmission, the aspects such as blood pressure maintains consistently, immune host defense, all play a very important role and participate in generation and the evolution of body various diseases.NO or a kind of important vascular relaxing factor, after vascular endothelial cell produces, be applied to vascular smooth muscle, through a series of biochemical reaction, produces c-GMP, make smooth muscle relaxation.For cardiovascular disease conditions such as alleviation hypertension, angina pectoris etc., there is good effect.A characteristic resonance frequency of NO molecule, exactly just at THz wave (THz ripple) wave band.By the THz ripple to organism radiation NO characteristic frequency, the growing amount of NO in body can be increased, play blood vessel dilating, regulate the effect of vascular flow amount.
THz wave (THz ripple) or be called that Terahertz ray (THz ray) is from the eighties of last century middle and late stage eighties, just by definite designation, scientists will be referred to as far ir ray before this.THz wave refers to the electromagnetic wave of frequency in 0.1THz to 10THz scope, wavelength probably 0.03 to 3mm scope, between microwave and infrared between.Up to the present, the application of THz technology mainly concentrates in above-described Molecular Detection and organism imaging.Experiment proves, the electromagnetic wave of this wave band has beyond thought biological effect, such as, affect Growth of Cells, gene expression etc.More surprisingly, usual millimeter wave and submillimeter can only be penetrated into the degree of depth of organism less than 1mm, but usually bring curative effect to the disease of human body depths internal organs.
In traditional Terahertz armarium, instrument and equipment only have treatment function, contrast diagnosis is not carried out to the effect before and after treatment, like this can only by the intuitive judgment of sufferer, certain drawback must be brought to the improvement of the effect for the treatment of and method.Although certain detection can be had by external instrument (physical parameter detector etc.) to the change of physiological parameter before and after treatment, but testing result does not have uniqueness and specific aim, and need purchase corresponding instrument and take up room, be unfavorable for the portable of overall instrument and comfortableness, be more unfavorable for that instrument moves towards from hospital the theory that community and family realize whole people's low cost health.
Summary of the invention
For solving the problem existing for above-mentioned prior art, the object of the present invention is to provide the Terahertz medical instrument of a kind of diagnosis, treatment one, its use is simple, easy to carry.
To achieve these goals, the invention provides a kind of THz wave medical instrument, comprise multiple probe and pop one's head in for driving and process the controller of the Information Monitoring that probe inputs, described probe comprises for there is the THz wave generator of THz wave and the acquisition electrode for carrying out electrocardiogram acquisition.
Preferably, described probe comprises the 3rd probe being provided with the first probe of LA acquisition electrode, the second probe of RA acquisition electrode and RL acquisition electrode.
Preferably, described probe is provided with the sucker for being adsorbed in intended treatment site, and described acquisition electrode is located in described sucker.
Preferably, the THz wave frequency that described Terahertz generator is launched is 0.1THZ-10THZ.
Preferably, the THz wave mid frequency that described Terahertz generator is launched is 0.15THZ.
Preferably, described controller comprises:
Described controller comprises:
Control treatment module: receive the instruction of human-computer interaction module generation and produce a drive singal, drives THz wave driver module or electrocardiogram acquisition module for selecting; Transfer and the Information Monitoring stored in analyzing stored module, analysis result is transferred in memory module;
THz wave driver module: receive the drive singal of control treatment module input thus the duty of control THz wave generator;
Electrocardiogram acquisition module: receive the drive singal of control treatment mould input thus the duty of control acquisition electrode, the electrocardiosignal of acquisition electrode feedback is gathered, and the ecg information collected is transferred to memory module;
Memory module: receive and store the ecg information of electrocardiogram acquisition module input and the analysis result of control treatment module input;
Human-computer interaction module: for the instruction of control treatment module transfer, and the input/output information of display and control processing module.
Preferably, described electrocardiogram acquisition module comprises:
Electrocardiogram acquisition chip: the drive singal receiving control treatment module, to export in an acquired signal to probe thus controls acquisition electrode and carry out electrocardiogram acquisition;
Flow-restriction: current limliting is carried out to acquired signal;
Pull-up unit: the electrocardiosignal for feeding back acquisition electrode is tentatively amplified, and the signal after amplifying is input in electrocardiogram acquisition chip;
Reference voltage module: for electrocardiogram acquisition module provides reference voltage level;
First impedance matching module: for carrying out impedance matching to the amplifier of electrocardiogram acquisition chip internal and high-pass filtering module;
Second impedance matching module: for carrying out impedance matching to the low-pass filtering module of electrocardiogram acquisition chip internal.
Preferably, described flow-restriction comprises: the first resistance, the second resistance, the 3rd resistance and the 7th electric capacity, and wherein, described first resistance one end is connected with the described 3rd RL acquisition electrode of popping one's head in, and the other end is connected with+IN the pin of described electrocardiogram acquisition chip; Described second resistance one end is connected with the described second RA acquisition electrode of popping one's head in, and the other end is connected with-IN the pin of described electrocardiogram acquisition chip; Described 3rd resistance one end is connected with the described first LA acquisition electrode of popping one's head in, and the other end is connected with the RLD pin of described electrocardiogram acquisition chip; Described 7th electric capacity one end is connected with the RLDFB pin of described electrocardiogram acquisition chip, and the other end is connected with the RLD pin of described electrocardiogram acquisition chip;
Described pull-up unit comprises: the 4th resistance and the 5th resistance, and wherein, described 4th resistance one end is connected with described first reference voltage, and the other end is connected with-IN the pin of described electrocardiogram acquisition chip; Described 5th resistance one end is connected with described first reference voltage, and the other end is connected with+IN the pin of described electrocardiogram acquisition chip;
Described reference voltage module comprises: the 6th resistance, the 7th resistance, the first electric capacity and the second electric capacity, wherein, wherein said first electric capacity is connected with the REFIN pin of described electrocardiogram acquisition chip with the one end after described 6th resistor coupled in parallel, and the other end is electrically connected with ground; Described 7th resistance one end is connected with described second reference voltage, and the other end is connected with the REFIN pin of described electrocardiogram acquisition chip; Described second electric capacity one end is connected with described second reference voltage, and the other end is connected to the GND pin of described electrocardiogram acquisition chip, ACDC pin and ground;
Described first impedance matching module comprises: the 8th resistance, the 9th resistance, the tenth resistance, the 3rd electric capacity and the 4th electric capacity, wherein, shown in the IAOUT pin of the 8th resistance one end and shown electrocardiogram acquisition chip and shown second impedance matching module be connected, the other end is connected with the tenth resistance with shown 9th resistance; The other end of shown 9th resistance is connected with the SW pin of shown electrocardiogram acquisition chip and is connected with the REFOUT pin of shown electrocardiogram acquisition chip by shown 4th electric capacity; The other end of shown tenth resistance is connected with the HPSENSE pin of shown electrocardiogram acquisition chip and crosses shown 3rd electric capacity and is connected with the HPDRIVE pin of shown electrocardiogram acquisition chip.
Described second impedance matching module comprises: the 11 resistance, the 12 resistance, the 13 resistance, the 14 resistance, the 5th electric capacity and the 6th electric capacity, wherein, described 12 resistance one end is connected by the REFOUT pin of described four or five electric capacity with described electrocardiogram acquisition chip after being connected with the OPAMP+ pin of described electrocardiogram acquisition chip; The other end is connected with described first impedance matching module by the 11 resistance, is connected by described 6th electric capacity with the OUT pin of described electrocardiogram acquisition chip simultaneously; Described 13 resistance one end is connected with the REFOUT pin of described electrocardiogram acquisition chip, and the other end is connected with the OPAMP-pin of described electrocardiogram acquisition chip; Described 14 resistance one end is connected with the OPAMP-pin of described electrocardiogram acquisition chip, and the other end is connected with the OUT pin of described electrocardiogram acquisition chip;
Preferably, described controller also comprises the galvanic power transfer module for alternating current being converted to THz wave medical instrument.
Preferably, described controller also comprises transport module, for the transmission of data.
Beneficial effect:
THz wave medical instrument provided by the invention, not only can carry out the treatment of cardiovascular disease to user, can also carry out electrocardiogram acquisition and also analyze the ecg information collected, thus reach the object of diagnosis to user.Meanwhile, the probe of THz wave medical instrument in the predetermined treatment of human body or diagnosis position by its sucker suction, carries out hand-held without the need to people, is convenient to user and operates.And THz wave medical instrument also has use advantage simple, easy to carry.
Accompanying drawing explanation
The structural representation of the THz wave medical instrument that Fig. 1 provides for one embodiment of the invention.
Fig. 2 is the profile of popping one's head in Fig. 1.
The principle framework figure of the controller that Fig. 3 provides for one embodiment of the invention.
The electrocardiogram acquisition module principle figure that Fig. 4 provides for one embodiment of the invention.
The THz wave driver module schematic diagram that Fig. 5 provides for one embodiment of the invention.
The THz wave medical instrument software flow pattern that Fig. 6 provides for one embodiment of the invention.
Detailed description of the invention
In order to set forth technical characterstic of the present invention and structure better, be described in detail below in conjunction with the preferred embodiments of the present invention and accompanying drawing thereof.
Consult Fig. 1, a kind of THz wave medical instrument that the present embodiment provides comprises the controller of popping one's head in and for driving the Information Monitoring popping one's head in and process probe input.
Consult Fig. 2, for the profile of probe, probe comprises THz wave generator 202, poly-ripple lens 203, sucker 204, acquisition electrode 201 and housing 205, wherein THz wave generator 202 comprises generator main body 2021 and waveguide window 2022, the core component of generator main body 2021 is indium phosphide Gunn diode, for launching the THz wave of 0.1T ~ 10T, in a kind of preferred embodiment, the THz wave mid frequency that generator main body 2021 is launched is 0.15THZ; Waveguide window 2022 is roughly disc, is arranged in generator main body 2021, and the THz wave that generator main body 2021 produces is launched through waveguide window 2022.Poly-ripple lens 203 are arranged on waveguide window 2022, and are covered by waveguide window 2022, assemble for the THz wave sent popping one's head in.THz wave generator 202 is contained in housing 205, and housing 205 lower end has the first through hole 2051, and the side of housing 205 offers the first guidewire port 2052, and waveguide window 2022, through the first through hole 2051, together enters in sucker 204 with the poly-ripple lens 203 of part.Sucker 204 is roughly bowl structure, comprise sucker sidewall 2041 and sucker chassis 2042, wherein, sucker sidewall 2041 inside is provided with the second through hole 2043 that sucker sidewall 2041 parallels, sucker sidewall 2041 is fixedly connected with housing 205, and the housing 205 of fixed connection place is provided with the second guidewire port 2053 relative to the second through hole 2043.Probe also comprises coaxial cable 206, and one end of coaxial cable 206 is connected to generator main body 2021, and the other end is through the first guidewire port 2052 extend to outside housing 205, and coaxial cable 206 end is provided with a plug 207 for being connected with controller 1.Acquisition electrode 201 one end is connected with the first plug 207, and the other end enters housing 205 inside then successively through the second guidewire port 2053 of housing 205 and the second through hole 2043 to sucker chassis 2042 of sucker sidewall 2041 through the first guidewire port 2052.When probe is used for the treatment of or diagnose, only need sucker 204 to be adsorbed in human body predetermined treatment or diagnosis position by sucker chassis 2042, carry out hand-held without the need to people, convenient operation personnel operate.
In the present embodiment, probe comprises the first probe 21, second probe 22 and the 3rd probe 23, wherein, the acquisition electrode of the first probe 21, second probe 22 and the 3rd probe 23, THz wave generator and plug are respectively: LA acquisition electrode, RA acquisition electrode and RL acquisition electrode; First THz wave generator, the second THz wave generator and the 3rd THz wave generator; First plug, the second plug and the 3rd plug.In order to pop one's head in control, controller 1 is provided with the first probe interface 181, second probe interface 182 and the 3rd probe interface 183 that match with the first plug, the second plug, the 3rd plug respectively; Meanwhile, controller 1 is also provided with the power interface 190 be connected with power supply.
Consult Fig. 3 simultaneously, for the principle framework figure of the controller that one embodiment of the invention provides, controller comprises: control treatment module 110: receive the instruction of human-computer interaction module 140 generation and produce a drive singal, THz wave driver module 120 or electrocardiogram acquisition module 130 is driven for selecting, transfer and the Information Monitoring stored in analyzing stored module 150, analysis result is transferred in memory module 150; THz wave driver module 120: receive the drive singal of control treatment module 110 thus the duty of control the first THz wave generator, the second THz wave generator and the 3rd THz wave generator; Electrocardiogram acquisition module 130: receive the drive singal of control treatment module 110 thus the duty of control acquisition electrode 201, the electrocardiosignal that acquisition electrode 201 feeds back is gathered, and the ecg information collected is transferred to memory module 150; Memory module 150: receive and store the ecg information of electrocardiogram acquisition module 130 transmission and the analysis result of control treatment module 110 transmission; Human-computer interaction module 140: for control treatment module 110 transfer instruction, and the input/output information of display and control processing module 110; Transport module 160: for the transmission of data; Power transfer module 170: alternating current is converted to the unidirectional current required for THz wave medical instrument.
Simultaneously see Fig. 4, THz wave driver module 120 comprises voltage transformation module 121 and driver module 122, and wherein voltage transformation module 121 is the running voltages be converted to by input voltage required for THz wave generator 202.Voltage transformation module 121 comprises voltage conversion chip 1211, 17 resistance R17, 18 resistance R18, 19 resistance R19, 20 resistance R20, 8th electric capacity C8, 9th electric capacity C9, tenth electric capacity C10, diode D1, inductance L 1 and the second audion Q2, wherein, 17 resistance R17 one end is connected to the 4th reference voltage V cc4, 6 pins of voltage conversion chip 1211 and the positive pole of the 8th electric capacity C8, the other end is connected to 1 pin of voltage conversion chip 1211, 7 pins, the source electrode of 8 pins and the second audion Q2, the minus earth of the 8th electric capacity C8, the grid of the second audion Q2 is connected with 2 pins of voltage conversion chip 1211, simultaneously by the 18 resistance R18 ground connection, the drain electrode of the second audion Q2 is connected with the negative pole of diode D1, the plus earth of diode D1, the drain electrode of the second audion Q2 is connected with the positive pole of driver module 122 with the tenth electric capacity C10 by inductance L 1, the minus earth of the tenth electric capacity C10.One end of 20 resistance R20 is connected with the positive pole of the tenth electric capacity C10, and the other end is connected with 5 pins of voltage conversion chip 1211 and passes through the 19 resistance R19 ground connection; Voltage conversion chip 1211 also comprises 4 pins of ground connection and 3 pins by the 9th electric capacity C9 ground connection; Wherein, the 8th electric capacity C8 and the tenth electric capacity C10 is electrochemical capacitor.4th reference voltage V cc4 is 9V in the present embodiment, and voltage conversion chip 1211 mainly adopts KA34063 chip, and after voltage transformation module 121 is changed, its output voltage is 3.5V.
Driver module 122 comprises the 15 resistance R15, the 16 resistance R16 and the first audion Q1, wherein, the outfan of voltage transformation module 121 is connected to after 15 resistance R15 one end is connected with the source electrode of the first audion Q1, the other end is connected to described control treatment module 110 by the 16 resistance R16 after being connected with the grid of the first audion Q1, the drain electrode of the first audion Q1 is connected with the THz wave generator 202 of probe, another interfacing ground of THz wave generator 202.When control treatment module 110 exports high level, the first audion Q1 conducting, the THz wave generator 202 of probe works; When control treatment module 110 output low level, the first audion Q1 ends, and the THz wave generator 202 of probe quits work.
Described electrocardiogram acquisition module 130 comprises: electrocardiogram acquisition chip 136: the drive singal receiving control treatment module, to export in an acquired signal to probe thus control acquisition electrode to carry out electrocardiogram acquisition; Flow-restriction 131: current limliting is carried out to acquired signal; Pull-up unit 132: the electrocardiosignal for feeding back acquisition electrode is tentatively amplified, and the signal after amplifying is input in electrocardiogram acquisition chip 136; Reference voltage module 133: for electrocardiogram acquisition mould 136 pieces provides reference voltage level; First impedance matching module 134: for carrying out impedance matching to the amplifier of electrocardiogram acquisition chip 136 inside and high-pass filtering module; Second impedance matching module 135: for carrying out impedance matching to the low-pass filtering module of electrocardiogram acquisition chip 136 inside.
Wherein, electrocardiogram acquisition chip 136 adopts AD8232, and certainly in other embodiments, electrocardiogram acquisition chip adopts also can adopt ADS1298.Flow-restriction 131 comprises: the first resistance R1, the second resistance R2, the 3rd resistance R3 and the 7th electric capacity C7, and wherein, the RL acquisition electrode popped one's head in 23 in first resistance R1 one end and the 3rd is connected, and the other end is connected with+IN the pin of electrocardiogram acquisition chip; The RA acquisition electrode popped one's head in 22 in second resistance R2 one end and second is connected, and the other end is connected with-IN the pin of electrocardiogram acquisition chip; The LA acquisition electrode popped one's head in 21 in 3rd resistance R3 one end and first is connected, and the other end is connected with the RLD pin of electrocardiogram acquisition chip; 7th electric capacity C7 one end is connected with the RLDFB pin of electrocardiogram acquisition chip, and the other end is connected with the RLD pin of electrocardiogram acquisition chip; In order to prevent, LA acquisition electrode drive current is excessive to be damaged human body, and in the present embodiment, the value of R3 is 360K Ω, and simultaneously in order to make the balance of RA acquisition electrode and RL acquisition electrode, R1 resistance value is identical with the resistance value of R2.
Pull-up unit 132 comprises: the 4th resistance R4 and the 5th resistance R5, and wherein, the 4th resistance R4 one end is connected with the first reference voltage V cc1, and the other end is connected with-IN the pin of electrocardiogram acquisition chip; 5th electric R5 hinders one end and is connected with the first reference voltage, and the other end is connected with+IN the pin of electrocardiogram acquisition chip.
Reference voltage module 133 comprises: the 6th resistance R6, the 7th resistance R7, the first electric capacity C1 and the second electric capacity C2, and wherein, wherein the first electric capacity C1 is connected with the REFIN pin of electrocardiogram acquisition chip with one end after the 6th resistance R6 parallel connection, and the other end is electrically connected with ground; 7th resistance R7 one end is connected with the second reference voltage V cc2, and the other end is connected with the REFIN pin of electrocardiogram acquisition chip; Second electric capacity C2 one end is connected with the second reference voltage V cc2, is connected the while of the other end with the GND pin of electrocardiogram acquisition chip, ACDC pin with ground.
First impedance matching module 134 comprises: the 8th resistance R8, the 9th resistance R9, the tenth resistance R10, the 3rd electric capacity C3 and the 4th electric capacity C4, wherein, 8th resistance one end is connected with the second impedance matching module 135 with the IAOUT pin of electrocardiogram acquisition chip, and the other end is connected with the tenth resistance R10 with the 9th resistance R9; The other end of the 9th resistance R9 is connected with the SW pin of electrocardiogram acquisition chip and is connected with the REFOUT pin of electrocardiogram acquisition chip 136 by the 4th electric capacity C4; The other end of the tenth resistance R10 is connected with the HPSENSE pin of electrocardiogram acquisition chip and crosses the 3rd electric capacity C3 and is connected with the HPDRIVE pin of electrocardiogram acquisition chip.
Second impedance matching module 135 comprises: the 11 resistance R11, the 12 resistance R12, the 13 resistance R13, the 14 resistance R14, the 5th electric capacity C5 and the 6th electric capacity C6, wherein, 12 resistance R12 one end is connected with the OPAMP+ pin of electrocardiogram acquisition chip, be connected with the REFOUT pin of electrocardiogram acquisition chip by the 5th electric capacity C5 device simultaneously, the other end is connected with the first impedance matching module 134 by the 11 resistance R11, is connected by the 6th electric capacity C6 with the OUT pin of electrocardiogram acquisition chip simultaneously; 13 resistance R13 one end is connected with the REFOUT pin of electrocardiogram acquisition chip, and the other end is connected with the OPAMP-pin of electrocardiogram acquisition chip; 14 resistance R14 one end is connected with the OPAMP-pin of electrocardiogram acquisition chip, and the other end is connected with the OUT pin of electrocardiogram acquisition chip.
Electrocardiogram acquisition chip 136 also comprises the SDN pin of the drive singal for receiving control treatment module, LOD+ and the LOD-pin of the monitoring that to come off for cardiac diagnosis lead and is connected to the FR pin of the 3rd reference voltage V cc3.Wherein, the magnitude of voltage of the first reference voltage V cc1, the second reference voltage V cc2, the 3rd reference voltage V cc3 is identical.
Compared with the electrocardiogram acquisition module of discrete element in prior art, the electrocardiogram acquisition module that the present embodiment provides have integrated level high, save the advantage that space and cost signal surely put.
Again see Fig. 1, Fig. 3, human-computer interaction module 140 comprises for the Keysheet module 141 to control treatment module 110 transfer instruction and the display module 142 for the input/output information of display and control processing module 110.In the present embodiment, display module 142 is LCD liquid crystal display screen, and the content that display module 142 shows comprises: the work of electrocardiogram acquisition module 130 or quit work and working time and working time state diagram; The work of the first THz wave generator, the second THz wave generator and the 3rd THz wave generator or quit work and working time of THz wave driver module 120 and time state figure; The Information Monitoring analysis result that control treatment module 110 exports.Keysheet module 141 is thin film type keyboard, comprise three groups of keyboards: probe selects keyboard 1411, comprise THz1 key, THz2 key, THz3 key, ECG key, be respectively used to the duty of selection first THz wave generator, the second THz wave generator and the 3rd THz wave generator or electrocardiogram acquisition module 130; Selection of time module 1412, comprises+key and-key, is respectively used to the working time increasing or reduce electrocardiogram acquisition module 130 or THz wave driver module 120; Systematical control options button 1413, comprises initiating key, Pause key and ON/OFF key, for controlling the duty of THz wave medical instrument.
Memory module 150, for receiving and storing the ecg information of electrocardiogram acquisition module 130 transmission and the analysis result of control treatment module 110 transmission, meanwhile, also for the data such as product complexity theory formula, complexity scale factor of pre-stored control treatment module 110.
Transport module 160 is Bluetooth communication modules, certainly, and in other embodiments also can for infrared transmission module or other be for carrying out the data transmission module of data transmission with computer or mobile terminal.
Power transfer module 170 comprises DC conversion modules and voltage reduction module, and wherein, DC conversion modules is used for alternating current to be converted to unidirectional current, and power to THz wave diagnosis and treatment, in the present embodiment, the galvanic voltage after changing is 9V; Voltage reduction module is used for the further blood pressure lowering of unidirectional current after by conversion, and for giving the chip power supply in THz wave diagnosis and treatment, in the present embodiment, the voltage after voltage reduction module blood pressure lowering is 3.3V.
Control treatment module 110 is formed primarily of MSP430FG4618 type single-chip microcomputer, and it is the core of THz wave medical instrument.When user operates Keysheet module 141, control treatment module 110 for receiving the instruction of Keysheet module 141, and controls corresponding module and makes corresponding action, controls display module 142 simultaneously and shows corresponding information.When electrocardio acquisition module 130 controls after acquisition electrode 201 carries out the collection of information, control treatment module 110 is transferred the Information Monitoring being stored into storage in memory module 150 and is analyzed, analysis result is input in memory module 150 simultaneously, controls display module 142 simultaneously and show corresponding information.The analysis of control treatment module 110 pairs of Information Monitorings comprises to be carried out digital filtering to Information Monitoring, carries out peak extraction and analysis of complexity to the filtered information of numeral.
At medical domain, the complexity of physiological system has quantized the adaptive capacity of body in consecutive variations environment, and 1. the complexity of health system is greater than the complexity of pathology system under normal circumstances; 2. pathology system is as aging, can reduce the adaptive capacity of system, and the quantity of information so entrained by physiological parameter diminishes, and corresponding airframe systems complexity reduces, and the reduction of complexity is the universals of pathology dynamical system.Product complexity theory carrys out the effect of description complete as far as possible physiological system state and assessment THz wave medical instrument use front and back by extracting useful information as much as possible in Information Monitoring.
Conveniently understand, product complexity theory is summarized as follows:
Its computational methods are by a string ordered series of numbers y (1), y (2) ... y (n) consecutive order forms one group of m dimensional vector, as m=2, then and vector
definition threshold value is r, calculate all two dimensional component with
distance lower than the number of threshold value
with the ratio of important sum, be defined as
the representative of its value is as component of a vector y
jat y
iaround time (according to threshold definitions), another component y
j+1also at y
i+1probability around.So be worth higher, the rule degree of representation signal is also higher.Each component is tried to achieve all in the above described manner
after get natural logrithm be added, be defined as φ
r m=2.When dimension is expanded to three-dimensional, namely during m=3, according to identical algorithms, we can try to achieve φ
r m (=2)+1, by preceding paragraph φ
r m=2deduct φ
r m (=2)+1, namely can be used to quantize this sequence signal by 2 D extension to unpredictability time three-dimensional, finally the relation of trying to achieve under different scale between its unpredictability with corresponding yardstick analyzed separately again.This method has been proved the unpredictability can distinguishing whether signal and has all had meaning under each mesostructure, the judgement that we can carry out macroscopically to the health status of goal systems by the complexity that calculates signal under each yardstick.
The THz wave medical instrument that the present embodiment provides also comprises Hardware drive module, Hardware drive module in the framework of system design between hardware and application software.The object of system hardware driver module exploitation is on designed hardware foundation, provides perfect in shape and function, facilitates the Programming Interface that application program uses.Wherein hardware circuit mainly provides the realization of basic function, and Hardware drive module is then integrated the programming resource such as various depositors, memorizer that hardware provides, and provide functional routine call, the application software for upper strata uses.In the present embodiment, for the ease of the transplanting of program, upgrading, amendment and system call, Hardware drive module adopts modularization programming, comprising: electrocardiogram acquisition program, display routine, interface program, timer program and THz control sequence.
In use, first the power interface 190 of controller is connected with power supply, the first probe 21, second probe 22 and the 3rd probe 23 are inserted in the first probe interface 181, second probe interface 182 and the 3rd probe interface 183 respectively.The mode of operation of THz wave medical instrument can be selected when user selects keyboard 1411 to operate to probe.When user selects THz1 key, THz2 key or THz3 key, for Therapeutic mode, now user by correspond first probe 21, second probe 22 or the 3rd probe 23 by sucker suction on the acupuncture point that will treat, control treatment module 110 drives THz wave driver module 120 to control corresponding first THz wave generator, the second THz wave generator or the 3rd THz wave generator and sends out and establish THz wave, terahertz radiation to the acupuncture point that will treat can reach the object for the treatment of.When user selects ECG key, be diagnostic mode, now user needs the first probe 21 to be adsorbed in left forearm, second probe 22 is adsorbed in right forearm, 3rd probe 23 is adsorbed in right lower limb, control treatment module 110 drives electrocardiogram acquisition module 130 control LA acquisition electrode, RA acquisition electrode and RL acquisition electrode to carry out electrocardiogram acquisition, is stored in memory module 150 by the ecg information collected in the process gathered.We are be described for 10 minutes for the acquisition time of information, ecg information=sample rate * the acquisition time of Information Monitoring, wherein gathering sample is be pre-stored in the fixed value in electrocardiogram acquisition module 130, in the present embodiment, sample rate is 125Hz, then the data of Information Monitoring are 75000.At the end of information gathering, control treatment module 110 ecg information transferred in memory module 150 carries out analyzing and result is outputted in memory module 150 and display module 142, so just reaches the object of diagnosis.
Consult Fig. 6, be the THz wave medical instrument software flow pattern that the present embodiment provides, according to flow chart, its concrete operations flow process is as follows:
1, after external power source connected by instrument, press the ON/OFF key in Keysheet module 141, then system enters beginning flow process; Whether and then system enters initialize flow, and system carries out Initialize installation, check every instruction and run normal, if normal, enter step 2.
2, to Keysheet module 141 scan round, key-press input has been checked whether.
If 3 return step 2 without key-press input, if there is key-press input, enter step 4.
4, check whether input has time delay and input signal whether to stablize, as input signal is unstable, have jitter phenomenon, then by de-twitter circuit debounce.After input signal is stable, then again checks it is truly have key-press input, if without key-press input, return step 2, if there is key-press input, enter step 5.
5, read key value, judge whether button is THz1, THz2 or THz3 button, if then transfer corresponding THz driver, if not then enter step 6.
6, judge whether button is ECG key, if then transfer electrocardiogram acquisition program and return step 2, if not then enter step 7.
7, determine whether+key or-key, if not then enter step 8 in this step; If then transfer timer program and return step 2.If enter this step, illustrating that user have selected the mode of operation of THz wave medical instrument, is namely Therapeutic mode or diagnostic mode, and the object of this step selects the working time of Therapeutic mode or diagnostic mode.
8, judge whether it is initiating key, if not then enter step 9; If then start corresponding program, namely when being chosen as Therapeutic mode, open the THz wave generator in corresponding probe, and according to the working time of time controling THz wave generator selected in step 7, call display routine by information displaying in display module 142 simultaneously, then return step 2; When being chosen as diagnostic mode, open probe and carry out electrocardiogram acquisition, and according to the time of time controling electrocardiogram acquisition selected in step 7, call storage program ecg information to be stored in memory module 150 simultaneously, call display routine by information displaying in display module 142, then return step 2.In the present embodiment, timer is countdown, and therefore along with treatment or diagnosis are in progress forward, timing then falls back, until be zero.In Therapeutic mode, when timing is zero, treatment terminates.In diagnostic mode, when timing is zero, information gathering terminates, and now control treatment module 110 ecg information transferred in memory module 150 carries out analyzing and result outputted in memory module 150 and display module 142, and diagnosis terminates.
9, judge whether it is Pause key, if not then return step 2, if then suspend the program run, and return step 2.
10, be unlatching at Therapeutic mode and diagnostic mode, and when not having button for a long time, system is closed automatically.
In sum, THz wave medical instrument provided by the invention, not only can carry out the treatment of cardiovascular disease to user, can also carry out electrocardiogram acquisition and also analyze the ecg information collected, thus reach the object of diagnosis to user.Meanwhile, the probe of THz wave medical instrument in the predetermined treatment of human body or diagnosis position by its sucker suction, carries out hand-held without the need to people, is convenient to user and operates.And THz wave medical instrument also has use advantage simple, easy to carry.
It should be noted that, in this article, the such as relational terms of first and second grades and so on is only used for an entity or operation to separate with another entity or operating space, and not necessarily requires or imply the relation that there is any this reality between these entities or operation or sequentially.And, term " comprises ", " comprising " or its any other variant are intended to contain comprising of nonexcludability, thus make to comprise the process of a series of key element, method, article or equipment and not only comprise those key elements, but also comprise other key elements clearly do not listed, or also comprise by the intrinsic key element of this process, method, article or equipment.When not more restrictions, the key element limited by statement " comprising ... ", and be not precluded within process, method, article or the equipment comprising described key element and also there is other identical element.
Although the present invention is described in detail with reference to its exemplary embodiment and shows, but will be understood by those skilled in the art that, when not departing from the spirit and scope of the present invention be defined by the claims, the various changes of form and details can be carried out to it.
Claims (8)
1. a THz wave medical instrument, it is characterized in that, comprise probe and pop one's head in for driving and process the controller of the Information Monitoring that probe inputs, described probe comprises for launching the THz wave generator of THz wave and the acquisition electrode for carrying out electrocardiogram acquisition;
Described controller comprises:
Control treatment module: receive the instruction of human-computer interaction module generation and produce a drive singal, drives THz wave driver module or electrocardiogram acquisition module for selecting; Transfer and the Information Monitoring stored in analyzing stored module, analysis result is transferred in memory module;
THz wave driver module: receive the drive singal of control treatment module input thus the duty of control THz wave generator;
Electrocardiogram acquisition module: receive the drive singal of control treatment module input thus the duty of control acquisition electrode, the electrocardiosignal of acquisition electrode feedback is gathered, and the ecg information collected is transferred to memory module;
Memory module: receive and store the ecg information of electrocardiogram acquisition module input and the analysis result of control treatment module input;
Human-computer interaction module: for the instruction of control treatment module transfer, and the input/output information of display and control processing module;
Described electrocardiogram acquisition module comprises:
Electrocardiogram acquisition chip: the drive singal receiving control treatment module, to export in an acquired signal to probe thus controls acquisition electrode and carry out electrocardiogram acquisition;
Flow-restriction: current limliting is carried out to acquired signal;
Pull-up unit: the electrocardiosignal for feeding back acquisition electrode is tentatively amplified, and the signal after amplifying is input in electrocardiogram acquisition chip;
Reference voltage module: for electrocardiogram acquisition module provides reference voltage level;
First impedance matching module: for carrying out impedance matching to the amplifier of electrocardiogram acquisition chip internal and high-pass filtering module;
Second impedance matching module: for carrying out impedance matching to the low-pass filtering module of electrocardiogram acquisition chip internal.
2. THz wave medical instrument according to claim 1, is characterized in that, described probe comprises the 3rd probe being provided with the first probe of LA acquisition electrode, the second probe of RA acquisition electrode and RL acquisition electrode.
3. THz wave medical instrument according to claim 1 and 2, is characterized in that, described probe is provided with sucker, and described acquisition electrode is located in described sucker.
4. THz wave medical instrument according to claim 1 and 2, is characterized in that, the THz wave frequency that described THz wave generator is launched is 0.1THZ-10THZ.
5. THz wave medical instrument according to claim 4, is characterized in that, the THz wave mid frequency that described THz wave generator is launched is 0.15THZ.
6. THz wave medical instrument according to claim 2, is characterized in that:
Described flow-restriction comprises: the first resistance, the second resistance, the 3rd resistance and the 7th electric capacity, and wherein, described first resistance one end is connected with the described 3rd RL acquisition electrode of popping one's head in, and the other end is connected with+IN the pin of described electrocardiogram acquisition chip; Described second resistance one end is connected with the described second RA acquisition electrode of popping one's head in, and the other end is connected with-IN the pin of described electrocardiogram acquisition chip; Described 3rd resistance one end is connected with the described first LA acquisition electrode of popping one's head in, and the other end is connected with the RLD pin of described electrocardiogram acquisition chip; Described 7th electric capacity one end is connected with the RLDFB pin of described electrocardiogram acquisition chip, and the other end is connected with the RLD pin of described electrocardiogram acquisition chip;
Described pull-up unit comprises: the 4th resistance and the 5th resistance, and wherein, described 4th resistance one end is connected with the first reference voltage, and the other end is connected with-IN the pin of described electrocardiogram acquisition chip; Described 5th resistance one end is connected with described first reference voltage, and the other end is connected with+IN the pin of described electrocardiogram acquisition chip;
Described reference voltage module comprises: the 6th resistance, the 7th resistance, the first electric capacity and the second electric capacity, wherein, wherein said first electric capacity is connected with the REFIN pin of described electrocardiogram acquisition chip with the one end after described 6th resistor coupled in parallel, and the other end is electrically connected with ground; Described 7th resistance one end is connected with the second reference voltage, and the other end is connected with the REFIN pin of described electrocardiogram acquisition chip; Described second electric capacity one end is connected with described second reference voltage, and the other end is connected to the GND pin of described electrocardiogram acquisition chip, ACDC pin and ground;
Described first impedance matching module comprises: the 8th resistance, the 9th resistance, the tenth resistance, the 3rd electric capacity and the 4th electric capacity, wherein, IAOUT pin and described second impedance matching module of described 8th resistance one end and described electrocardiogram acquisition chip are connected, and the other end is connected with the tenth resistance with described 9th resistance; The other end of described 9th resistance is connected with the SW pin of described electrocardiogram acquisition chip and is connected with the REFOUT pin of described electrocardiogram acquisition chip by described 4th electric capacity; The other end of described tenth resistance is connected with the HPSENSE pin of described electrocardiogram acquisition chip and crosses described 3rd electric capacity and is connected with the HPDRIVE pin of described electrocardiogram acquisition chip;
Described second impedance matching module comprises: the 11 resistance, the 12 resistance, the 13 resistance, the 14 resistance, the 5th electric capacity and the 6th electric capacity, wherein, described 12 resistance one end is connected with the REFOUT pin of described electrocardiogram acquisition chip by described 5th electric capacity after being connected with the OPAMP+ pin of described electrocardiogram acquisition chip; The other end is connected with described first impedance matching module by the 11 resistance, is connected by described 6th electric capacity with the OUT pin of described electrocardiogram acquisition chip simultaneously; Described 13 resistance one end is connected with the REFOUT pin of described electrocardiogram acquisition chip, and the other end is connected with the OPAMP-pin of described electrocardiogram acquisition chip; Described 14 resistance one end is connected with the OPAMP-pin of described electrocardiogram acquisition chip, and the other end is connected with the OUT pin of described electrocardiogram acquisition chip.
7. THz wave medical instrument according to claim 1, is characterized in that, described controller also comprises the galvanic power transfer module for alternating current being converted to THz wave medical instrument.
8. THz wave medical instrument according to claim 1, is characterized in that, described controller also comprises transport module, for the transmission of data.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104644155A (en) * | 2014-12-20 | 2015-05-27 | 王莹 | Electrocardiogram and cardiac color Doppler ultrasound all-in-one machine |
| CN106599594B (en) * | 2016-12-22 | 2019-08-13 | 白云绮 | Human Digital Model and disease treatment system based on Terahertz quantum wave information |
| CN107485793B (en) * | 2017-07-03 | 2019-05-14 | 西安电子科技大学 | A kind of MM wave therapeutic instrument |
| CN107297016B (en) * | 2017-08-01 | 2020-01-03 | 张建英 | PICC vein catheterization intelligent control operation instrument for leukemia patient chemotherapy |
| CN108392740A (en) * | 2018-01-26 | 2018-08-14 | 合肥驼峰电子科技发展有限公司 | The time-control device of MM wave therapeutic instrument |
| CN108968937A (en) * | 2018-07-23 | 2018-12-11 | 山东美泽赫生理技术有限公司 | A kind of blood pressure monitoring device and monitoring method |
| CN109731232B (en) * | 2019-01-10 | 2022-02-15 | 鲍玉珍 | Non-interference terahertz wave physiotherapy equipment for leukemia |
| CN109718473A (en) * | 2019-01-17 | 2019-05-07 | 冷新涛 | A kind of quantum cells resonance instrument |
| CN115813406A (en) * | 2022-12-24 | 2023-03-21 | 北京津发科技股份有限公司 | EEG sensor circuit, method and device |
| CN116549852B (en) * | 2023-06-26 | 2023-10-03 | 江苏智慧工场技术研究院有限公司 | Nerve therapeutic instrument convenient to carry |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895742A (en) * | 2012-10-12 | 2013-01-30 | 中国科学院深圳先进技术研究院 | Terahertz treatment instrument and probe thereof |
| CN103170064A (en) * | 2013-03-27 | 2013-06-26 | 深圳先进技术研究院 | Integral probe for diagnosis and treatment |
| CN103169450A (en) * | 2013-03-08 | 2013-06-26 | 深圳先进技术研究院 | Terahertz (THz) needle movement all-in-one machine |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010010192A1 (en) * | 2010-03-04 | 2011-09-08 | Siemens Aktiengesellschaft | Medical examination and / or treatment device |
-
2013
- 2013-10-29 CN CN201310526355.XA patent/CN103520842B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895742A (en) * | 2012-10-12 | 2013-01-30 | 中国科学院深圳先进技术研究院 | Terahertz treatment instrument and probe thereof |
| CN103169450A (en) * | 2013-03-08 | 2013-06-26 | 深圳先进技术研究院 | Terahertz (THz) needle movement all-in-one machine |
| CN103170064A (en) * | 2013-03-27 | 2013-06-26 | 深圳先进技术研究院 | Integral probe for diagnosis and treatment |
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