CN103392946A - Pig feed additive capable of effectively improving immunity and intestinal health - Google Patents
Pig feed additive capable of effectively improving immunity and intestinal health Download PDFInfo
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Abstract
The invention provides a pig feed additive capable of effectively improving immunity and intestinal health. The pig feed additive comprises mixed Chinese herbal medicine powder, a compound polysaccharide extractive, a microecological preparation, a yeast cell wall extractive, beneficial lignin, lipoic acid, phytase, choline chloride and carriers, wherein the carriers are defatted rice bran and wheat middling. The additive is scientific in combination, can effectively improve the immunity of a pig, reduces the morbidity of the pig, can replace or partially replace microbiotic and the like used in feed, can improve the intestinal health of the pig, promotes the pig to digest and absorb the feed, facilitates purifying sanitation of a shed, protects and improves an ecological environment of the shed, facilitates promoting healthy and orderly development of the feed and the animal husbandry, and is of great importance in improving the raising efficiency and reducing a raising risk.
Description
Technical field
The present invention relates to a kind of pig's feed additive, especially relate to a kind of feed addictive that can effectively improve pig immunity and improve chitling road health, belong to the feed feed additive field.
Background technology
In recent years, the food-safety problem that causes because of antibiotics feed addictive abuse appears in the newspapers again and again, and the direct and indirect economic loss number that causes thus is startling to the huge people of allowing, and the environmental problem of bringing thus in addition also should not be underestimated.Antibiotic has can not be by the characteristic of the complete metabolism of humans and animals body, form mainly with original shape and active metabolite is discharged to external by ight soil greatly, through a series of biotransformations such as absorption, photodissociation, hydrolysis and microbial degradations, the direct influence ecological environment of meeting, the remote-effects health.Swine disease is the maximum risk of cultivation simultaneously, and reducing the pig incidence of disease is to be difficult to a great problem of breaking through in aquaculture, is seriously restricting the development of pig industry.
The enteron aisle of pig is the main place that food digestion absorbs, and the healthy growth of keeping pig is had important effect.At enteron aisle, the various nutriments in chyme are broken down into various small-molecule substances, through enteron aisle fine hair, absorb and enter blood and lymph, for the body each several part, utilize.In addition, in the defence process of body, enteron aisle also plays an important role.Improve the chitling road healthy, be conducive to improve feed digestibility, improve the use value of feed, can also strengthen the immunity of pig simultaneously, to the active influence that grown of pig.
Therefore developing a kind of natural, nutrition, additive that toxic and side effect is little improves the immunity of pig and improves seem particularly important of chitling road health; can not only reduce antibiotic use; to protect mankind is healthy; can also reduce the pig incidence of disease; reduce the cultivation risk; be conducive to promote feed and the healthy and orderly development of livestock,, to improving culture benefit, reduce the cultivation risk significant.
Summary of the invention
The object of the present invention is to provide a kind of effective raising immunity and the pig feed additive that improves intestinal health.This additive can strengthen the immunity of pig, reduces the incidence of disease of pig, is conducive to reduce antibiotic use, and this additive can also improve chitling road health simultaneously, promotes the pig growth, shortens marketing time, increases economic benefit and promotes culture efficiency.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of effective raising immunity and the pig feed additive that improves intestinal health, mixed by weight by following raw material: mix Chinese herbal medicine powder 8-10 part, complex polysaccharide extract 3-5 part, probiotics 3-5 part, yeast cell wall extract 4-5 part, prebiotic lignin 1-3 part, lipoic acid 0.1-0.5 part, phytase 0.2-0.4 part, Choline Chloride 0.1-0.3 part, 100 parts altogether of carrier and raw materials, all the other are carrier.
Described mixing Chinese herbal medicine powder preparation method is as follows: with white fungus, matrimony vine and cloves 1:(2-3 in mass ratio): 1 under-60 to-80 ℃ freezing 12h-24h, pulverize, vacuum drying, dryly pulverized 60 mesh sieves after complete again; With Poria cocos and honeysuckle-leaf 3:(1-2 in mass ratio) co-grinding, cross 60 mesh sieves; Merge twice crushed material and namely obtain the mixing Chinese herbal medicine powder.
The preparation method of described complex polysaccharide extract: selected white fungus and Poria cocos are pulverized, and white fungus and Poria cocos be 1:(3-4 in mass ratio) proportioning, cross 50 mesh sieves, add 85% ethanol of 2 times of gross masses, refluxing extraction 1-1.5h, vacuum filtration, get filter residue.Add 5 times of deionized waters in filter residue, then add 1% cellulase, keep 40 ℃ of temperature, keep and stirred 30 minutes; Then pour in ultrasonic extractor, then add 5-10 times of water, ultrasonic 30 minutes, temperature 70 C, ultrasonic power 80-100W.Vacuum filtration, get filtrate, and is concentrated, and spray-drying is pulverized, and crosses 80 mesh sieves, obtains the complex polysaccharide extract.
The preparation method of described probiotics is as follows:
(1) expansion of bacterial classification is cultivated: adopt slant strains to enlarge step by step and cultivate the seed liquor that obtains Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium, three bacterial classifications use respectively MRS culture medium, broth bouillon and BBL culture medium;
(2) seed liquor of Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium is pressed 1:1:2 and mixes, with 20%-25%(V/W) inoculum concentration be inoculated in fermentation medium, cultivate 48-60h under 36-38 ℃, make fermentate.Fermentate ,-45 to-55 ℃ of lower freeze dryings, is pulverized 80 mesh sieves, obtained probiotics;
Described fermentation medium: 60 parts of maize straws, wheat bran 10-20 part, yeast soak powder 2-4 part, glucose 5-10 part, sodium chloride 0.1-0.2 part, magnesium sulfate 0.01-0.05 part, manganese sulfate 0.03-0.05 part and pulverize respectively in mass ratio, cross 40 mesh sieves, mix, under 121 ℃ sterilizing 30 minutes, be cooled to room temperature, spray gross mass 1/4-1/3 sterilized water.
Described carrier be defatted rice bran and wheat time powder by the 3:1 co-grinding, cross 40 mesh sieves and get final product.
Add in pig feed per ton that this additive of 600-1000 gram mixes, granulates, packing gets final product.
Beneficial effect
Mix Chinese herbal medicine powder and be comprised of multiple Chinese herbal medicine, contain the several functions composition, white fungus, matrimony vine and cloves are conducive to the fragmentation of cell membrane after superfreeze is processed, and in cell, active material more easily is absorbed; Poria cocos contains abundant dietary fiber and physiologically active ingredient, is conducive to small bowel peristalsis, and regulating intestinal canal is healthy; The complex polysaccharide extract can promote the digestion power of pig, strengthens the immunity of pig; Probiotics can be regulated chitling road flora, improves the chitling road healthy; In yeast cell wall extract, the functional form carbohydrate of yeast cells outer wall can, in conjunction with multiple mycotoxin, improve animal health by absorbing poisonous substance and pathogen to cell membrane; Prebiotic lignin comprises solubility and soluble dietary fiber simultaneously, can accelerate small bowel peristalsis, and the growth that is beneficial to probio is also arranged simultaneously.
Feed addictive compatibility science in the present invention, can effectively improve the immunity of pig, reduces the pig incidence of disease, reduces the uses in feed such as antibiotic; It is healthy that this additive can also improve the chitling road in addition, promotes the eupepsy of pig to feed, is conducive to simultaneously purify the column home health, protects and improve the column home ecological environment; And this additive main component is all natural products, has the characteristics such as safety, nutrition, toxic and side effect is little, is conducive to promote feed and the healthy and orderly development of livestock, and human health is had positive effect, belongs to the feed addictive of safe green.
Concrete enforcement
Below by specific embodiment explanation the present invention.
Embodiment 1
A kind of effective raising immunity and the pig feed additive that improves intestinal health, mixed by weight by following raw material: mix 10 parts of Chinese herbal medicine powders, 5 parts of complex polysaccharide extracts, 5 parts of probioticses, 5 parts of yeast cell wall extracts, 3 parts, prebiotic lignin, 0.5 part of lipoic acid, 0.4 part of phytase, 0.3 part of Choline Chloride, 100 parts altogether, raw material and carrier, all the other are carrier.
Described Chinese herbal medicine powder preparation method is as follows:, with white fungus, matrimony vine and cloves 1:3:1 freezing 24h under-80 ℃ in mass ratio, pulverize, vacuum drying, dryly pulverized 60 mesh sieves after complete again; , with Poria cocos and honeysuckle-leaf 3:2 co-grinding in mass ratio, cross 60 mesh sieves; Merge twice crushed material and namely obtain the mixing Chinese herbal medicine powder.
The preparation method of described complex polysaccharide extract: selected white fungus and Poria cocos are pulverized, and white fungus and Poria cocos be the 1:4 proportioning in mass ratio, crosses 50 mesh sieves, adds 85% ethanol of 2 times of gross masses, refluxing extraction 1.5h, and vacuum filtration, get filter residue.Add 5 times of deionized waters in filter residue, then add 1% cellulase, keep 40 ℃ of temperature, keep and stirred 30 minutes; Then pour in ultrasonic extractor, then add 10 times of water, ultrasonic 30 minutes, temperature 70 C, ultrasonic power 100W.Vacuum filtration, get filtrate, and is concentrated, and spray-drying is pulverized, and crosses 80 mesh sieves, obtains the complex polysaccharide extract.
The preparation method of described probiotics is as follows:
(1) expansion of bacterial classification is cultivated: adopt slant strains to enlarge step by step and cultivate the seed liquor that obtains Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium, three bacterial classifications use respectively MRS culture medium, broth bouillon and BBL culture medium;
(2) seed liquor of Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium is pressed 1:1:2 and mixes, with 20%-25%(V/W) inoculum concentration be inoculated in fermentation medium, cultivate 60h under 38 ℃, make fermentate.Fermentate ,-55 ℃ of lower freeze dryings, is pulverized 80 mesh sieves, obtained probiotics;
Described fermentation medium is for 60 parts of maize straws, 20 parts, wheat bran, yeast soak 4 parts, powder, 10 parts of glucose, 0.2 part, sodium chloride, 0.05 part, magnesium sulfate, 0.05 part of pulverizing respectively of manganese sulfate in mass ratio, cross 40 mesh sieves, mix, under 121 ℃ sterilizing 30 minutes, be cooled to room temperature, spray gross mass 1/3 sterilized water.
Described carrier be defatted rice bran and wheat time powder by the 3:1 co-grinding, cross 40 mesh sieves and get final product.
Add in pig feed per ton that this additive of 1000 grams mixes, granulates, packing gets final product.
Embodiment 2
A kind of effective raising immunity and the pig feed additive that improves intestinal health, mixed by weight by following raw material: mix 9 parts of Chinese herbal medicine powders, 4 parts of complex polysaccharide extracts, 4 parts of probioticses, 4 parts of yeast cell wall extracts, 2 parts, prebiotic lignin, 0.3 part of lipoic acid, 0.3 part of phytase, 0.2 part of Choline Chloride, 100 parts altogether of carrier and raw materials, all the other are carrier.
Described Chinese herbal medicine powder preparation method is as follows:, with white fungus, matrimony vine and cloves 1:3:1 freezing 18h under-75 ℃ in mass ratio, pulverize, vacuum drying, dryly pulverized 60 mesh sieves after complete again; , with Poria cocos and honeysuckle-leaf 3:2 co-grinding in mass ratio, cross 60 mesh sieves; Merge twice crushed material and namely obtain the mixing Chinese herbal medicine powder.
The preparation method of described complex polysaccharide extract: selected white fungus and Poria cocos are pulverized, and white fungus and Poria cocos be the 1:3 proportioning in mass ratio, crosses 50 mesh sieves, adds 85% ethanol of 2 times of gross masses, refluxing extraction 1.5h, and vacuum filtration, get filter residue.Add 5 times of deionized waters in filter residue, then add 1% cellulase, keep 40 ℃ of temperature, keep and stirred 30 minutes; Then pour in ultrasonic extractor, then add 8 times of water, ultrasonic 30 minutes, temperature 70 C, ultrasonic power 95W.Vacuum filtration, get filtrate, and is concentrated, and spray-drying is pulverized, and crosses 80 mesh sieves, obtains the complex polysaccharide extract.
The preparation method of described probiotics is as follows:
(1) expansion of bacterial classification is cultivated: adopt slant strains to enlarge step by step and cultivate the seed liquor that obtains Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium, three bacterial classifications use respectively MRS culture medium, broth bouillon and BBL culture medium;
(2) seed liquor of Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium is pressed 1:1:2 and mixes, with 22%(V/W) inoculum concentration be inoculated in fermentation medium, cultivate 54h under 37 ℃, make fermentate; Fermentate ,-50 ℃ of lower freeze dryings, is pulverized 80 mesh sieves, obtained probiotics;
Described fermentation medium: 60 parts of maize straws, 18 parts, wheat bran, yeast soak 3 parts, powder, 8 parts of glucose, 0.15 part, sodium chloride, 0.03 part, magnesium sulfate, 0.04 part of pulverizing respectively of manganese sulfate in mass ratio, cross 40 mesh sieves, mix, under 121 ℃ sterilizing 30 minutes, be cooled to room temperature, spray gross mass 1/3 sterilized water.
Described carrier be defatted rice bran and wheat time powder by the 3:1 co-grinding, cross 40 mesh sieves and get final product.
Add in pig feed per ton that this additive of 800 grams mixes, granulates, packing gets final product.
Embodiment 3
A kind of effective raising immunity and the pig feed additive that improves intestinal health, mixed by weight by following raw material: mix 8 parts of Chinese herbal medicine powders, 3 parts of complex polysaccharide extracts, 3 parts of probioticses, 4 parts of yeast cell wall extracts, 1 part, prebiotic lignin, 0.1 part of lipoic acid, 0.2 part of phytase, 0.1 part of Choline Chloride, 100 parts altogether of carrier and raw materials, all the other are carrier.
Described Chinese herbal medicine powder preparation method is as follows:, with white fungus, matrimony vine and cloves 1:2:1 freezing 12h under-60 ℃ in mass ratio, pulverize, vacuum drying, dryly pulverized 60 mesh sieves after complete again; , with Poria cocos and honeysuckle-leaf 3:1 co-grinding in mass ratio, cross 60 mesh sieves; Merge twice crushed material and namely obtain the mixing Chinese herbal medicine powder.
The preparation method of described complex polysaccharide extract: selected white fungus and Poria cocos are pulverized, and white fungus and Poria cocos be the 1:3 proportioning in mass ratio, crosses 50 mesh sieves, adds the ethanol of 2 times 85% of gross mass, refluxing extraction 1h, and vacuum filtration, get filter residue.Add 5 times of deionized waters in filter residue, then add 1% cellulase, keep 40 ℃ of temperature, keep and stirred 30 minutes; Then pour in ultrasonic extractor, then add 5 times of water, ultrasonic 30 minutes, temperature 70 C, ultrasonic power 80W.Vacuum filtration, get filtrate, and is concentrated, and spray-drying is pulverized, and crosses 80 mesh sieves, obtains the complex polysaccharide extract.
The preparation method of described probiotics is as follows:
(1) expansion of bacterial classification is cultivated: adopt slant strains to enlarge step by step and cultivate the seed liquor that obtains Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium, three bacterial classifications use respectively MRS culture medium, broth bouillon and BBL culture medium;
(2) seed liquor of Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium is pressed 1:1:2 and mixes, with 20%-25%(V/W) inoculum concentration be inoculated in fermentation medium, cultivate 48h under 36 ℃, make fermentate.Fermentate ,-45 ℃ of lower freeze dryings, is pulverized 80 mesh sieves, obtained probiotics;
Described fermentation medium: 60 parts of maize straws, 10 parts, wheat bran, yeast soak 2 parts, powder, 5 parts of glucose, 0.1 part, sodium chloride, 0.01 part, magnesium sulfate, 0.03 part of pulverizing of manganese sulfate in mass ratio, cross 40 mesh sieves, mix, under 121 ℃ sterilizing 30 minutes, be cooled to room temperature, spray gross mass 1/4 sterilized water.
Described carrier be defatted rice bran and wheat time powder by the 3:1 co-grinding, cross 40 mesh sieves and get final product.
Add in pig feed per ton that this additive of 600 grams mixes, granulates, packing gets final product.
Embodiment 4 product results of use
The embodiment of the present invention 2 feed addictive result of use tests.
Test method: select Guangnan (Zhanjiang) the family rich subordinate of feed corporation,Ltd pig farm, select each 80 of age in days, body weight close healthy sow, piglet and growing and fattening pigs, all be divided at random 2 groups (test group and control groups), test group add that 800g embodiment 2 makes the invention product, control group does not add product of the present invention; Fed continuously 60 days; Test pig is carried out daily observation and detection.
Compare with control group, use the invention feed addictive can obtain following effect:
(1) number born of sow on average increases by 0.8, the average 300g that increases in the piglet birth;
(2) before and after the childbirth, the prevention of sow constipation number of times reduces 30-40%;
(3) the diarrhea rate test group of piglet is lacked more than 30% than control group;
(4) sensory evaluation scores is carried out in the hair color of test pig, the test group scoring reaches 8.8 minutes, and control group is 6.3 minutes;
(5) test group has increased more than 10% than the weight average of control group;
(6) stink of the column home of test group is obviously light than control group.
Conclusion: product of the present invention can effectively strengthen the immunity of pig, reduces the incidence of disease of pig, can improve the chitling road simultaneously healthy, has alleviated the stink of discharging ight soil, and otherness is remarkable.
This product is green product, belongs to the green feed field, can substitute or the use of part substitute antibiotics in feed, and feed and cultivation industry are had active influence, has broad market prospects.
Claims (6)
1. one kind is effectively improved immunity and the pig feed additive that improves intestinal health, it is characterized in that being mixed by weight by following raw material: mix Chinese herbal medicine powder 8-10 part, complex polysaccharide extract 3-5 part, probiotics 3-5 part, yeast cell wall extract 4-5 part, prebiotic lignin 1-3 part, lipoic acid 0.1-0.5 part, phytase 0.2-0.4 part, Choline Chloride 0.1-0.3 part, totally 100 parts of carrier and raw materials, all the other are carrier, carrier be defatted rice bran and wheat time powder by the 3:1 co-grinding, cross 40 mesh sieves;
Described mixing Chinese herbal medicine comprises: white fungus, matrimony vine, cloves, Poria cocos and honeysuckle-leaf;
Described probiotics is Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium Mixed Microbes.
2. a kind of effective raising immunity and improve the pig feed additive of intestinal health according to claim 1, it is characterized in that being mixed by weight by following raw material: mix 9 parts of Chinese herbal medicine powders, 4 parts of complex polysaccharide extracts, 4 parts of probioticses, 4 parts of yeast cell wall extracts, 2 parts, prebiotic lignin, 0.3 part of lipoic acid, 0.3 part of phytase, 0.2 part of Choline Chloride, 100 parts altogether of carrier and raw materials, all the other are carrier, carrier be defatted rice bran and wheat time powder by the 3:1 co-grinding, cross 40 mesh sieves;
Described mixing Chinese herbal medicine comprises: white fungus, matrimony vine, cloves, Poria cocos and honeysuckle-leaf;
Described probiotics is for containing Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium Mixed Microbes.
3. described mixing Chinese herbal medicine powder according to claim 1 and 2, it is characterized in that its preparation method is as follows: with white fungus, matrimony vine and cloves 1:2-3:1 freezing 12h-24h under-60 to-80 ℃ in mass ratio, pulverize, vacuum drying, pulverized 60 mesh sieves after drying is complete again; , with Poria cocos and honeysuckle-leaf 3:1-2 co-grinding in mass ratio, cross 60 mesh sieves; Merge twice crushed material and namely obtain the mixing Chinese herbal medicine powder.
4. described complex polysaccharide extract according to claim 1 and 2, it is characterized in that its preparation method is as follows: selected white fungus and Poria cocos are pulverized, and white fungus and Poria cocos be the 1:3-4 proportioning in mass ratio, crosses 50 mesh sieves, 85% ethanol that adds 2 times of gross masses, refluxing extraction 1-1.5h, vacuum filtration, get filter residue, add 5 times of deionized waters in filter residue, add again 1% cellulase, keep 40 ℃ of temperature, keep and stirred 30 minutes; Then pour in ultrasonic extractor, then add 5-10 times of water, ultrasonic 30 minutes, temperature 70 C, ultrasonic power 80-100W; Vacuum filtration, get filtrate, and is concentrated, and spray-drying is pulverized, and crosses 80 mesh sieves, obtains the complex polysaccharide extract.
5. described probiotics according to claim 1 and 2 is characterized in that its preparation method comprises the following steps:
(1) expansion of bacterial classification is cultivated: adopt slant strains to enlarge step by step and cultivate the seed liquor that obtains Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium, three bacterial classifications use respectively MRS culture medium, broth bouillon and BBL culture medium;
(2) seed liquor of Lactobacillus delbrueckii, bacillus subtilis and Bifidobacterium is pressed 1:1:2 and mixes, with 20%-25%(V/W) inoculum concentration be inoculated in fermentation medium, cultivate 48-60h under 36-38 ℃, make fermentate; Fermentate ,-45 to-55 ℃ of lower freeze dryings, is pulverized 80 mesh sieves, obtained probiotics;
Described fermentation medium: 60 parts of maize straws, wheat bran 10-20 part, yeast soak powder 2-4 part, glucose 5-10 part, sodium chloride 0.1-0.2 part, magnesium sulfate 0.01-0.05 part, manganese sulfate 0.03-0.05 part and pulverize respectively in mass ratio, cross 40 mesh sieves, mix, under 121 ℃ sterilizing 30 minutes, be cooled to room temperature, spray gross mass 1/4-1/3 sterilized water.
6. a kind of effective raising immunity as claimed in claim 1 or 2 and the purposes of pig feed additive in pig feed of improving intestinal health, is characterized in that, the addition of described feed addictive in pig feed per ton is the 600-1000 gram.
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