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CN101856280A - A woven artificial blood vessel and the manufacturing method thereof - Google Patents

A woven artificial blood vessel and the manufacturing method thereof Download PDF

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Publication number
CN101856280A
CN101856280A CN 201010195463 CN201010195463A CN101856280A CN 101856280 A CN101856280 A CN 101856280A CN 201010195463 CN201010195463 CN 201010195463 CN 201010195463 A CN201010195463 A CN 201010195463A CN 101856280 A CN101856280 A CN 101856280A
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China
Prior art keywords
blood vessel
artificial blood
tissue
woven
spiral
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 201010195463
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Chinese (zh)
Inventor
李毓陵
杨夫全
丁辛
王璐
李倩
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Donghua University
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Donghua University
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Filing date
Publication date
Application filed by Donghua University filed Critical Donghua University
Priority to CN 201010195463 priority Critical patent/CN101856280A/en
Publication of CN101856280A publication Critical patent/CN101856280A/en
Pending legal-status Critical Current

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  • Materials For Medical Uses (AREA)

Abstract

The invention relates to a woven artificial blood vessel, which comprises an artificial blood vessel, which is a spiral corrugation structure having a convex part and a concave part on the inner surface, wherein the convex part and the concave part are formed by coiling long floats (1) at equal interval. The spiral distribution is an inclined corrugation structure. The method for manufacturing the woven artificial blood vessel comprises a spiral corrugation forming procedure and a spiral corrugation shaping procedure and specifically comprises the following steps: 1) performing a film flip method on the tissue including the long floats (1) to obtain a new tissue; 2) taking the tissue as the surface tissue of an artificial blood vessel and the new tissue resulting from the flip as the internal tissue of the artificial blood vessel; and 3) combining the two tissues obtaining from the step 2) into a tissue chart of the artificial blood vessel, loading the tissues onto a machine and weaving the tissues into the artificial blood vessel having a spiral surface; the spiral corrugation shaping procedure comprises loading a corresponding internal or external screw mould on the internal or external side of the artificial blood vessel and performing a thermal shaping treatment in an automatic shaping oven. The invention is capable of solving the problems caused by the corrugation treatment in existing technology, such as the short service life of the artificial blood vessel and the occurrence of thrombus.

Description

A kind of woven blood vessel and manufacture method thereof
Technical field
The invention belongs to artificial human organ field, particularly relate to a kind of woven blood vessel and manufacture method thereof.
Background technology
Relative knitted blood vessel, woven blood vessel are stiffening, the bendable folding endurance is poor.When artificial blood vessel bends, blood vessel blockage very easily occurs, thereby increase the probability of thrombosis.In order to improve woven blood vessel's bendable folding endurance, people carry out artificial blood vessel thermal finalization usually and handle, and make artificial blood vessel form ripple (as shown in Figure 1).The ripple on artificial blood vessel surface can increase the longitudinal extension and the flexure unber lateral of artificial blood vessel, prevents to occur when the bending of artificial blood vessel blood vessel blockage, hinders flowing of blood.
After the ripple processing, woven blood vessel's surface forms crest and trough one by one, and the problem of Cun Zaiing is like this: 1) changed the original surface area of blood vessel.But woven blood vessel's structure is tight, yarn to move freely the space very little, on the crest location that surface area has increased, the diminishing of fabric through filling density.So this processing method has worsened the structure (as shown in Figure 2) of artificial blood vessel.The change of blood vessel structure can cause the difference of blood vessel biomechanical property everywhere, will become the weak joint part of whole blood vessel sometimes, thereby may cause artificial blood vessel mechanical property in vivo to quicken the service life that decay influences artificial blood vessel.2) the flow through blood of Wave crest and wave trough can produce different speed because different pipeline section is long-pending, thereby causes eddy current, increases the probability of thrombosis.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of woven blood vessel and manufacture method thereof, to solve the problem of the ripple processing brings in the prior art artificial blood vessel service life, thrombosis etc.
The technical solution adopted for the present invention to solve the technical problems is: a kind of woven blood vessel is provided, comprises artificial blood vessel, described artificial blood vessel is an inner surface by the floating long line concavo-convex inclined screw ripple struction that constitutes of spiral uniformly-spaced.
A kind of method of making the woven blood vessel, its step comprise, helical corrugation molding procedure and helical corrugation shaping process.
Described helical corrugation molding procedure may further comprise the steps:
1) tissue that will comprise floating long line obtains new organization by the egative film inversion method;
2) new organization that obtains as artificial blood vessel organization table tissue, with upset with tissue is as organizing in the artificial blood vessel tissue;
3) with step 2) two tissues be combined into the organization charts of artificial blood vessel, the artificial blood vessel that looming weaving becomes surperficial spiral to distribute.
Described helical corrugation shaping process is meant the outside or the inboard that corresponding female thread or external screw thread mould is contained in artificial blood vessel, the heat treatment of finalizing the design in the automatic sizing baking oven.
The heat treated temperature of described typing is 180 ℃-200 ℃, and the time is 20s-60s.
Tissue in the described step 1) is that 2/1 twill-weave and 6/30 changes the oblique cord weave that warp rib is combined into; Described new organization obtains through the egative film inversion method for tissue.
Tissue in the described step 1) is that tissue is split in the variation of plain weave and the compound composition of 6/30 angle twill; Described new organization obtains through the egative film inversion method for tissue.
Beneficial effect
The present invention directly weaves out the artificial blood vessel that contains the helical corrugation distortion, handles the artificial blood vessel that obtains stablizing spiral lamination through thermal finalization again.This artificial blood vessel provides enough surface areas, guarantee in the thermal finalization processing procedure, not change artificial blood vessel everywhere through filling density, finally reach the purpose that does not worsen blood vessel structure; Simultaneously, spiral ripple can improve the hydromechanics performance of blood, handles the thrombosis probability of bringing thereby reduce ripple, simultaneously:
1) improved the structural homogeneity of artificial blood vessel.
2) ripple one-shot forming, the burden of minimizing post-treatment operation.
3) improve the hemodynamics performance of artificial blood vessel, improved the unimpeded rate of artificial blood vessel.
4) directly to floating long line thermal finalization, protect the main body yarn biomechanical property.
5) can obtain the helical corrugation artificial blood vessel of different helical angles.
Description of drawings
Fig. 1 is the woven blood vessel's sketch after the ripple processing in the prior art;
Fig. 2 is through filling density distribution sketch (wherein solid line is a warp thread, and dotted line is a weft yarn, and cylindrical is a crest, and interior circle is a trough) around the prior art medium wave peak trough;
Fig. 3 is woven blood vessel's sketch of the present invention;
Fig. 4 is a floating long line scattergram in the pipe embryo of the present invention;
Fig. 5 is a of organization charts in the embodiment of the invention;
Fig. 6 is the b of organization charts in the embodiment of the invention;
Fig. 7 is the c of organization charts in the embodiment of the invention;
Fig. 8 is the d of organization charts in the embodiment of the invention.
The specific embodiment
Below in conjunction with specific embodiment, further set forth the present invention.Should be understood that these embodiment only to be used to the present invention is described and be not used in and limit the scope of the invention.Should be understood that in addition those skilled in the art can make various changes or modifications the present invention after the content of having read the present invention's instruction, these equivalent form of values fall within the application's appended claims institute restricted portion equally.
Embodiment 1
Present embodiment is applicable to the woven blood vessel of internal diameter greater than 10mm, and used is polyester multifilament through weft yarn.The used basic organization of fabric is that 2/1 twill-weave and 6/30 changes warp rib.Both are combined into oblique cord weave a (as shown in Figure 5).Organization charts's (as shown in Figure 6) that oblique raised line a organization charts is overturn and obtains organizing b according to the egative film inversion method.Be tubular tissue table organization with oblique cord weave a at last, with oblique cord weave b be tubular tissue in the tissue, so just obtain helical corrugation tubulose organization charts.Last machine manufacturing obtains the artificial blood vessel that inner surface has the floating long line of spiral distribution.
At pitch between formed each oblique raised line and the short size model of determining the thermal finalization threaded mold of floating long line length, and adopt the SKD11 die steel material to make.
The thermal finalization threaded mold is packed in the artificial blood vessel, finalize the design in RJ-430 automatic sizing baking oven, setting temperature is 200 ℃, and the time is 20s.
Embodiment 2
Selecting plain weave and 6/30 angle twill for use is basic organization.Both compound compositions change to split organizes c (as shown in Figure 7), as the table organization of tubing; Variation split organize c to obtain organizing organization charts's (as shown in Figure 8) of d, as tissue in the tubing by the egative film inversion method.Looming weaving obtains the artificial blood vessel that surfaces externally and internally all has the floating long line of spiral distribution.
This artificial blood vessel typing needs two moulds, a floating long line typing to the artificial blood vessel inner surface, and another is to the floating long line typing of artificial blood vessel outer surface, and the former is processed into the external screw thread mould, and the latter is processed into the female thread mould.At pitch between formed each oblique raised line and the short size model of determining the thermal finalization threaded mold of floating long line length, and adopt the SKD11 die steel material to make.
The thermal finalization threaded mold is packed in the artificial blood vessel, finalize the design in RJ-430 automatic sizing baking oven, setting temperature is 200 ℃, and the time is 20s.

Claims (7)

1. a woven blood vessel comprises artificial blood vessel, it is characterized in that: described artificial blood vessel is that inner surface is by floating the uniformly-spaced concavo-convex inclined screw ripple struction of spiral formation of long line (1).
2. method of making the described woven blood vessel of claim 1, it is characterized in that: its step comprises, helical corrugation molding procedure and helical corrugation shaping process.
3. a kind of woven blood vessel's according to claim 2 manufacture method, it is characterized in that: described helical corrugation molding procedure may further comprise the steps:
1) tissue that will comprise floating long line (1) obtains new organization by the egative film inversion method;
2) new organization that obtains as artificial blood vessel organization table tissue, with upset with tissue is as organizing in the artificial blood vessel tissue;
3) with step 2) two tissues be combined into the organization charts of artificial blood vessel, the artificial blood vessel that looming weaving becomes surperficial spiral to distribute.
4. a kind of woven blood vessel's according to claim 2 manufacture method, it is characterized in that: described helical corrugation shaping process is meant the outside or the inboard that corresponding female thread or external screw thread mould is contained in artificial blood vessel, the heat treatment of finalizing the design in the automatic sizing baking oven.
5. a kind of woven blood vessel's according to claim 4 manufacture method, it is characterized in that: the heat treated temperature of described typing is 180 ℃-200 ℃, and the time is 20s-60s.
6. a kind of woven blood vessel's according to claim 2 manufacture method is characterized in that: the tissue in the described step 1) is that 2/1 twill-weave and 6/30 changes the oblique cord weave that warp rib is combined into; Described new organization obtains through the egative film inversion method for tissue.
7. a kind of woven blood vessel's according to claim 2 manufacture method, it is characterized in that: the tissue in the described step 1) is that tissue is split in the variation of plain weave and the compound composition of 6/30 angle twill; Described new organization obtains through the egative film inversion method for tissue.
CN 201010195463 2010-06-08 2010-06-08 A woven artificial blood vessel and the manufacturing method thereof Pending CN101856280A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920531A (en) * 2012-11-08 2013-02-13 东华大学 Production method of woven artificial blood vessel
CN103498308A (en) * 2013-09-27 2014-01-08 东华大学 Tubular fiber-based artificial blood vessel coating/grafting device and using method thereof
CN105107020A (en) * 2015-08-25 2015-12-02 清华大学 Artificial blood vessel prepared by weaving PHBV (polyhydroxybutyrate-hydroxyvalerate) and PLA (polylactic acid) in blending manner
CN112168445A (en) * 2020-09-21 2021-01-05 东华大学 Y-shaped integrated corrugated netted braided tracheal stent and manufacturing method thereof
CN113456293A (en) * 2020-03-31 2021-10-01 脉通医疗科技(嘉兴)有限公司 Preparation method of artificial blood vessel and artificial blood vessel
CN113696385A (en) * 2021-08-18 2021-11-26 山东黄河三角洲纺织科技研究院有限公司 Artificial blood vessel heat setting device
WO2023149582A1 (en) * 2022-02-07 2023-08-10 株式会社ハイレックスコーポレーション Artificial blood vessel and method for manufacturing artificial blood vessel
CN116831780A (en) * 2023-07-05 2023-10-03 北京航空航天大学 Corrugated small-caliber artificial blood vessel and manufacturing method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3337673A (en) * 1958-07-31 1967-08-22 Us Catheter & Instr Corp Uniformly corrugated prosthesis and process of making same
WO1987005796A1 (en) * 1986-03-27 1987-10-08 Advanced Vascular Technologies, Inc. Vascular prostheses apparatus and method of manufacture
CN1142932A (en) * 1995-08-11 1997-02-19 上海丝绸科学技术研究所 Artificial blood vessel interweaved by silk and polyester fibre long filament
US6053938A (en) * 1994-08-27 2000-04-25 Aesculap Ag & Co. Kg Textile vessel prosthesis, process for its production and apparatus for its production
CN1522675A (en) * 2003-02-21 2004-08-25 无锡莱福纶生物材料有限公司 Machine knitting artificial blood vessel without pleat in the internal wall, and its making method
JP2006334278A (en) * 2005-06-06 2006-12-14 Nippon Acp Kk Artificial blood vessel and method of manufacturing the same

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3337673A (en) * 1958-07-31 1967-08-22 Us Catheter & Instr Corp Uniformly corrugated prosthesis and process of making same
WO1987005796A1 (en) * 1986-03-27 1987-10-08 Advanced Vascular Technologies, Inc. Vascular prostheses apparatus and method of manufacture
US6053938A (en) * 1994-08-27 2000-04-25 Aesculap Ag & Co. Kg Textile vessel prosthesis, process for its production and apparatus for its production
CN1142932A (en) * 1995-08-11 1997-02-19 上海丝绸科学技术研究所 Artificial blood vessel interweaved by silk and polyester fibre long filament
CN1522675A (en) * 2003-02-21 2004-08-25 无锡莱福纶生物材料有限公司 Machine knitting artificial blood vessel without pleat in the internal wall, and its making method
JP2006334278A (en) * 2005-06-06 2006-12-14 Nippon Acp Kk Artificial blood vessel and method of manufacturing the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《河南纺织高等专科学校学报》 20010920 张巧玲 管状织物的设计研究 3 , 2 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920531A (en) * 2012-11-08 2013-02-13 东华大学 Production method of woven artificial blood vessel
CN103498308A (en) * 2013-09-27 2014-01-08 东华大学 Tubular fiber-based artificial blood vessel coating/grafting device and using method thereof
CN103498308B (en) * 2013-09-27 2016-01-06 东华大学 A kind of tubular fiber base artificial blood vessel coating/grafting device and using method
CN105107020A (en) * 2015-08-25 2015-12-02 清华大学 Artificial blood vessel prepared by weaving PHBV (polyhydroxybutyrate-hydroxyvalerate) and PLA (polylactic acid) in blending manner
CN113456293A (en) * 2020-03-31 2021-10-01 脉通医疗科技(嘉兴)有限公司 Preparation method of artificial blood vessel and artificial blood vessel
CN112168445A (en) * 2020-09-21 2021-01-05 东华大学 Y-shaped integrated corrugated netted braided tracheal stent and manufacturing method thereof
CN113696385A (en) * 2021-08-18 2021-11-26 山东黄河三角洲纺织科技研究院有限公司 Artificial blood vessel heat setting device
WO2023149582A1 (en) * 2022-02-07 2023-08-10 株式会社ハイレックスコーポレーション Artificial blood vessel and method for manufacturing artificial blood vessel
CN116831780A (en) * 2023-07-05 2023-10-03 北京航空航天大学 Corrugated small-caliber artificial blood vessel and manufacturing method thereof

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Open date: 20101013