CN101422178A - Berberine imidacloprid water agent - Google Patents
Berberine imidacloprid water agent Download PDFInfo
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- CN101422178A CN101422178A CNA2008101821560A CN200810182156A CN101422178A CN 101422178 A CN101422178 A CN 101422178A CN A2008101821560 A CNA2008101821560 A CN A2008101821560A CN 200810182156 A CN200810182156 A CN 200810182156A CN 101422178 A CN101422178 A CN 101422178A
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- Prior art keywords
- imidacloprid
- jamaicin
- berberine
- extraction liquid
- plant extraction
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- 239000005906 Imidacloprid Substances 0.000 title claims abstract description 50
- 229940056881 imidacloprid Drugs 0.000 title claims abstract description 50
- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical compound [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 title claims abstract description 50
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 29
- YBHILYKTIRIUTE-UHFFFAOYSA-N berberine Chemical compound C1=C2CC[N+]3=CC4=C(OC)C(OC)=CC=C4C=C3C2=CC2=C1OCO2 YBHILYKTIRIUTE-UHFFFAOYSA-N 0.000 title claims abstract description 22
- 229940093265 berberine Drugs 0.000 title claims abstract description 22
- QISXPYZVZJBNDM-UHFFFAOYSA-N berberine Natural products COc1ccc2C=C3N(Cc2c1OC)C=Cc4cc5OCOc5cc34 QISXPYZVZJBNDM-UHFFFAOYSA-N 0.000 title claims abstract description 22
- 239000003795 chemical substances by application Substances 0.000 title claims description 19
- 239000003814 drug Substances 0.000 claims abstract description 19
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 229940079593 drug Drugs 0.000 claims abstract description 7
- WITLAWYGGVAFLU-UHFFFAOYSA-N 3-(6-methoxy-1,3-benzodioxol-5-yl)-8,8-dimethylpyrano[2,3-f]chromen-4-one Chemical compound C1=CC(C)(C)OC2=CC=C(C(C(C3=CC=4OCOC=4C=C3OC)=CO3)=O)C3=C21 WITLAWYGGVAFLU-UHFFFAOYSA-N 0.000 claims description 62
- 241000196324 Embryophyta Species 0.000 claims description 28
- 238000000605 extraction Methods 0.000 claims description 25
- 239000007788 liquid Substances 0.000 claims description 24
- 241000218691 Cupressaceae Species 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- 235000016068 Berberis vulgaris Nutrition 0.000 claims description 5
- 235000004347 Perilla Nutrition 0.000 claims description 5
- 240000000528 Ricinus communis Species 0.000 claims description 5
- 235000004443 Ricinus communis Nutrition 0.000 claims description 5
- 238000005516 engineering process Methods 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims description 4
- 235000014347 soups Nutrition 0.000 claims description 4
- 241001083847 Berberis Species 0.000 claims description 3
- 240000000724 Berberis vulgaris Species 0.000 claims description 3
- 241000229722 Perilla <angiosperm> Species 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims description 3
- 239000012530 fluid Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 238000001556 precipitation Methods 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 244000124853 Perilla frutescens Species 0.000 claims description 2
- 239000006286 aqueous extract Substances 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 241000607479 Yersinia pestis Species 0.000 abstract description 9
- 231100000419 toxicity Toxicity 0.000 abstract description 7
- 230000001988 toxicity Effects 0.000 abstract description 7
- 241001465754 Metazoa Species 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 239000002917 insecticide Substances 0.000 abstract description 4
- 239000000419 plant extract Substances 0.000 abstract description 4
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 239000003960 organic solvent Substances 0.000 abstract description 2
- 231100000674 Phytotoxicity Toxicity 0.000 abstract 1
- 230000007246 mechanism Effects 0.000 abstract 1
- 231100000572 poisoning Toxicity 0.000 abstract 1
- 230000000607 poisoning effect Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 244000241838 Lycium barbarum Species 0.000 description 13
- 235000015459 Lycium barbarum Nutrition 0.000 description 13
- 241000238631 Hexapoda Species 0.000 description 12
- 239000000575 pesticide Substances 0.000 description 12
- 241001124076 Aphididae Species 0.000 description 8
- 230000003449 preventive effect Effects 0.000 description 7
- 230000001018 virulence Effects 0.000 description 6
- 230000000857 drug effect Effects 0.000 description 5
- 239000003905 agrochemical Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 241000411851 herbal medicine Species 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 229930013930 alkaloid Natural products 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000000749 insecticidal effect Effects 0.000 description 2
- 231100000636 lethal dose Toxicity 0.000 description 2
- 231100000225 lethality Toxicity 0.000 description 2
- 231100000053 low toxicity Toxicity 0.000 description 2
- 230000002186 photoactivation Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 1
- KAATUXNTWXVJKI-NSHGMRRFSA-N (1R)-cis-(alphaS)-cypermethrin Chemical compound CC1(C)[C@@H](C=C(Cl)Cl)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 KAATUXNTWXVJKI-NSHGMRRFSA-N 0.000 description 1
- WCXDHFDTOYPNIE-RIYZIHGNSA-N (E)-acetamiprid Chemical compound N#C/N=C(\C)N(C)CC1=CC=C(Cl)N=C1 WCXDHFDTOYPNIE-RIYZIHGNSA-N 0.000 description 1
- AULWPXHFRBLPAE-UHFFFAOYSA-N 6-chloropyridine Chemical compound ClC1=C=CC=C[N]1 AULWPXHFRBLPAE-UHFFFAOYSA-N 0.000 description 1
- 239000005875 Acetamiprid Substances 0.000 description 1
- 102000012440 Acetylcholinesterase Human genes 0.000 description 1
- 108010022752 Acetylcholinesterase Proteins 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229940022698 acetylcholinesterase Drugs 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 229960002587 amitraz Drugs 0.000 description 1
- QXAITBQSYVNQDR-ZIOPAAQOSA-N amitraz Chemical compound C=1C=C(C)C=C(C)C=1/N=C/N(C)\C=N\C1=CC=C(C)C=C1C QXAITBQSYVNQDR-ZIOPAAQOSA-N 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 150000005516 benzylisoquinolines Chemical class 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000002283 diesel fuel Substances 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 235000013348 organic food Nutrition 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- -1 polyoxyethylene Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- GUOHRXPYGSKUGT-UHFFFAOYSA-N quinolizinium Chemical compound C1=CC=CC2=CC=CC=[N+]21 GUOHRXPYGSKUGT-UHFFFAOYSA-N 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
本发明涉及一种小檗碱吡虫啉水剂，其特征在于是由吡虫啉与小檗碱植物提取液复配制成的水剂，其中吡虫啉的含量为1～2mg/L，小檗碱植物提取液的含量为15～20mg/L。本发明将作用机理互异的两种杀虫剂复配，不仅有利于克服害虫抗药性，而且可提高单药的特性，如可大大降低了吡虫啉的用量，提高了吡虫啉对害虫的毒力，提高小檗碱植物提取液对害虫的防效；同时，本发明以水为基质，解决了有机溶剂产生的易燃和药害问题，可避免人、畜中毒及环境污染。The invention relates to a berberine imidacloprid water preparation, which is characterized in that it is a water preparation compounded by imidacloprid and berberine plant extract, wherein the content of imidacloprid is 1-2 mg/L, and the content of berberine plant extract is The content is 15-20mg/L. In the present invention, two kinds of insecticides with different action mechanisms are compounded, which not only helps to overcome the resistance of pests, but also improves the characteristics of single drugs, such as greatly reducing the consumption of imidacloprid and improving the toxicity of imidacloprid to pests. Improve the pest control effect of the berberine plant extract; at the same time, the invention uses water as the substrate, solves the problems of flammability and phytotoxicity caused by organic solvents, and can avoid human and animal poisoning and environmental pollution.
Description
Technical field
The invention belongs to pesticide production technology field, particularly relate to a kind of berberine imidacloprid water agent.
Background technology
Jamaicin is the active ingredient in medicinal plant barberry, the golden cypress, belong to the different quinoline of benzyl in the alkaloid (benzyl-isoquinoline) class of giving repeated exhortations, chemical formula is: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxzolo[5,6-a] quinolizinium, structure is as follows:
Jamaicin is a kind of active insecticidal components, and insect is had photoactivation toxicity, and promptly the lethality to insect can improve several times even thousands of times under illumination, can be used to make the quality raw materials composition of botanical biological pesticide.But because single agent quick-acting of botanical biological pesticide is relatively poor in producing, thereby exist the insect drug effect slowly, field efficacy is poor, the spray medicine often, defective such as extension rate is lower.
Imidacloprid is to be the synthetic nitro-methylene-type systemic insecticide of template with nicotine, and English common name imidacloprid, chemical name are 1-[(6-chloro-pyridine) methyl]-4,5-dihydro-N-nitro-1-hydrogen imidazoles-2-amine.Its chemical constitution is as follows:
The effect target body of Imidacloprid is a nicotinic acid acetylcholinesterase acceptor, and it is malfunctioning to disturb the pest movements nervous system that chemical signal is transmitted---behind the insect contact medicament, the nervous centralis normal conduction is obstructed, and makes its paralysis dead.Imidacloprid has wide spectrum, efficient, low toxicity, interior absorption is strong, the longevity of residure long, low-residual, insect is difficult for producing resistance, to characteristics such as people, animal, plant and natural enemies securities, and have tag, stomach toxicity and the multiple drug effect of interior suction, quick-acting is good, higher preventive effect was promptly arranged in 1 day behind the medicine, residual life, reached about 25 days.Drug effect and temperature are proportionate, temperature height, good disinsection effect.Be mainly used in the control sucking pest.But at present used consumption is big, has proved that various pests has produced pesticide resistance.
The complex preparation of not seeing at present jamaicin and Imidacloprid exists.
The complex preparation of not seeing at present jamaicin and Imidacloprid exists.
Summary of the invention
Purpose of the present invention just is to provide a kind of berberine imidacloprid water agent.
The present invention is achieved through the following technical solutions:
A kind of berberine imidacloprid water agent is characterized in that it being that wherein the content of Imidacloprid is 1～2mg/L by Imidacloprid and the composite aqua of making of jamaicin plant extraction liquid, and the content of jamaicin plant extraction liquid is 15～20mg/L;
Above-mentioned jamaicin plant extraction liquid is for by weight to be the aqueous extract of raw material after 40～50 parts of barberries, 1～2 part of golden cypress, 45～50 parts of purple perillas, 2～3 parts of mixing of castor-oil plant, and wherein every milliliter contains the jamaicin plant extraction liquid and is equivalent to contain the 1g crude drug;
The preparation technology of above-mentioned jamaicin plant extraction liquid is: take by weighing barberry, golden cypress, purple perilla and castor-oil plant by weight, with its pulverizing, soaked 12～24 hours with clear water, the clear water addition is as the criterion to cover medicinal material, stir between soak period 2～3 times, be heated to 100 ℃ then, kept slight boiling condition 1 hour, squeeze and filter, filtrate carry out centrifugal or place precipitation.Then, the dregs of a decoction after the filter were soaked 3～4 hours again, boiled after 1 hour and refilter, twice filtered fluid mixed, the filtrate cryogenic vacuum is concentrated into every milliliter of soup and is equivalent to contain the 1g crude drug, obtains the jamaicin plant extraction liquid.
Above-mentioned jamaicin plant extraction liquid promptly is the alkaloids plant pesticide of insecticidal active ingredient with the jamaicin.Because jamaicin has photoactivation toxicity to insect, the jamaicin plant extraction liquid is subjected to after the optical excitation that the toxicity to insect increases in degraded, therefore not only improve the drug effect of insecticide, and avoided residual lastingly in environment, met the desired environment concordance of public nuisance-free agricultural chemicals; Secondly, it has selectivity preferably, and is extremely low to the toxicity of non-target organism; The 3rd, resistance development slows down.
The present invention is based on above-mentioned plant extraction liquid---and the jamaicin plant extraction liquid, compound imidacloprid is made berberine imidacloprid water agent.The present invention is with two kinds of pesticide compositionals of mechanism of action inequality, not only help overcoming pest resistance to insecticide, and can improve the characteristic of single medicine, greatly reduce the consumption of Imidacloprid, improved the virulence of Imidacloprid, improved the preventive effect of jamaicin plant extraction liquid insect to insect; Simultaneously, the present invention is a matrix with water, has solved the inflammable and drug injury problem that organic solvent produces, and can avoid people, animal to poison and environmental pollution.
The present invention makes the Chinese herbal medicine pesticide technology that new breakthrough arranged, and has captured the difficult problem of the quick-acting difference of current Chinese herbal medicine agricultural chemicals, has brought into play Chinese herbal medicine agricultural chemicals low toxicity, noresidue, nuisanceless, characteristics such as the soup absorption affinity is strong, duration of efficacy length.And raw material sources of the present invention are wide, production cost is low, have anesthesia concurrently, tag, multi-efficiency such as stomach toxicity, interior suction, desinsection, antibacterial integrated control effect are good, can be particularly useful for the production of traditional Chinese medicine, organic food, pollution-free food and pollution-free food in a plurality of fields extensive uses such as agricultural, forestry, animal husbandry.
Below for the test of pesticide effectiveness of berberine imidacloprid water agent of the present invention:
Virulence experiment:
Infusion process is adopted in test, and the matrimony vine blade that will have the matrimony vine aphid is dipped in the medicament, observes examination worm mortality then, and calculates lethality.
The result shows: the former medicine of Imidacloprid is to the virulence regression equation y=1.2534x+3.4021 of matrimony vine aphid, LD
50(lethal dose of 50) is 18.8251; Berberine imidacloprid water agent is to the virulence regression equation y=1.4981x+4.4781 of matrimony vine aphid, LD
50(lethal dose of 50) is 2.2301ug/ml.The above results explanation jamaicin plant extract has obvious synergistic effect to Imidacloprid, and berberine imidacloprid water agent is 8.44 times of Imidacloprid to the virulence of aphid.
The berberine imidacloprid water agent field trial:
Experimental field be located at Yinchuan City Vegetable Research Institute matrimony vine experimental field, No. 1, the peaceful Qi of life in 2 years, and experimental field management is strict, and water and fertilizer condition is good.
Result of the test: behind the berberine imidacloprid water agent medicine behind 1 day, medicine 14 days preventive effects be respectively 95.26%, 91.40%, with 14 days preventive effect 85.49% no marked differences behind 1 day preventive effect 92.17%, the medicine behind the medicine of 10% Imidacloprid.
Test shows that the preventive effect of berberine imidacloprid water agent (Imidacloprid content is 2.3%) is suitable with the preventive effect of 10% Imidacloprid, not only significantly improves the control action of jamaicin plant extraction liquid to target pest, and significantly reduces the consumption of Imidacloprid.Berberine imidacloprid water agent shows lasting effect preferably simultaneously.
A large number of experiments show that the composite berberine imidacloprid water agent of making of jamaicin plant extraction liquid through Plant Protection Research Inst. of Ningxia Academy of Agriculture and Forest Sci in the period of 2007～2008 liang, wherein the content of Imidacloprid is 1～2mg/L, the content of jamaicin plant extraction liquid is 15～20mg/L, can reduce the Imidacloprid consumption, improve the virulence of Imidacloprid simultaneously insect; And it is slow to the insect drug effect to have solved the jamaicin plant extraction liquid, and field efficacy is poor, sprays medicine often, the defective of interior suction osmosis difference.
The agricultural chemicals usage amount is very big on the matrimony vine at present.Insect pest took place very seriously during matrimony vine produced, and was mainly aphid, goitre mite etc., and the pesticide variety of use is very many, comprises Imidacloprid, Acetamiprid, chlopyrifos, A Wei diesel oil, beta-cypermethrin and Amitraz etc.; Pesticide application uses with the matrimony vine plucking time and is difficult to stagger, and matrimony vine belongs to the season of growth repeatedly plucks, and adopts once in 7 days, and a growth can be adopted 14～18 times in season, easily causes harvesting very near with the pesticide application time interval even overlap.Therefore lack very much the special-purpose non-toxic environment-protection pesticide on the matrimony vine.Above evidence the present invention has good control efficiency to the matrimony vine aphid, can be used as the special-purpose aphicide of matrimony vine, generally speaking, dilutes 2000 times of spraying uses the matrimony vine aphid is had good control efficiency.Also can be used for simultaneously the control of aphid on other traditional Chinese medicines, vegetables, the crops.
Embodiment
The preparation of 1 jamaicin plant extraction liquid
Take by weighing 40～50 parts of barberries by weight, 1～2 part of golden cypress, 45～50 parts of purple perillas, 2～3 parts of castor-oil plants, pulverizing the back soaked 12～24 hours with clear water, the clear water addition is as the criterion to cover medicinal material, stir between soak period 2～3 times, be heated to 100 ℃ then, maintenance slight boiling condition squeeze and filter after 1 hour, filtrate is carried out centrifugal or is placed precipitation, simultaneously the dregs of a decoction after the filter were soaked 3～4 hours again, boil after 1 hour and filter, twice filtered fluid mixed, and the filtrate cryogenic vacuum is concentrated into every milliliter of soup and is equivalent to contain the 1g crude drug, obtains the jamaicin plant extraction liquid.
The preparation of 2 berberine imidacloprid water agents
Imidacloprid is dissolved in acetone is made into the full solution that closes, press 1～2 part of Imidacloprid saturated solution, the volume ratio that the jamaicin plant extraction liquid is 15～20 parts is mixed, the surfactant dodecyl sodium sulfate, alkylphenol polyoxyethylene or the fatty alcohol-polyoxyethylene ether that add 15～30 parts then, it plays the wetting osmosis of opening up in aqua.48～50 parts of moisturizings, the content of Imidacloprid is that the content of 1～2mg/L, jamaicin plant extraction liquid is 15～20mg/L in the feasible aqua that is mixed.
Claims (3)
1, a kind of berberine imidacloprid water agent is characterized in that it being that wherein the content of Imidacloprid is 1～2mg/L by Imidacloprid and the composite aqua of making of jamaicin plant extraction liquid, and the content of jamaicin plant extraction liquid is 15～20mg/L.
2, according to the described berberine imidacloprid water agent of claim 1, it is characterized in that above-mentioned jamaicin plant extraction liquid for by weight to be the aqueous extract of raw material after 40～50 parts of barberries, 1～2 part of golden cypress, 45～50 parts of purple perillas, 2～3 parts of mixing of castor-oil plant, wherein every milliliter contains the jamaicin plant extraction liquid and is equivalent to contain the 1g crude drug.
3, according to claim 1 or 2 described berberine imidacloprid water agents, the preparation technology who it is characterized in that above-mentioned jamaicin plant extraction liquid is: take by weighing barberry, golden cypress, purple perilla and castor-oil plant by weight, with its pulverizing, soaked 12～24 hours with clear water, the clear water addition is as the criterion to cover medicinal material, stirs between soak period 2～3 times, be heated to 100 ℃ then, kept slight boiling condition 1 hour, squeeze and filter, filtrate is carried out centrifugal or is placed precipitation.Then, the dregs of a decoction after the filter were soaked 3～4 hours again, boiled after 1 hour and refilter, twice filtered fluid mixed, the filtrate cryogenic vacuum is concentrated into every milliliter of soup and is equivalent to contain the 1g crude drug, obtains the jamaicin plant extraction liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101821560A CN101422178B (en) | 2008-11-14 | 2008-11-14 | Berberine imidacloprid water agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101821560A CN101422178B (en) | 2008-11-14 | 2008-11-14 | Berberine imidacloprid water agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101422178A true CN101422178A (en) | 2009-05-06 |
| CN101422178B CN101422178B (en) | 2011-04-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008101821560A Expired - Fee Related CN101422178B (en) | 2008-11-14 | 2008-11-14 | Berberine imidacloprid water agent |
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| Country | Link |
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| CN (1) | CN101422178B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103444729A (en) * | 2013-09-05 | 2013-12-18 | 肇庆长龙生物科技有限公司 | Bactericidal pharmaceutical composition and applications thereof |
| CN103483444A (en) * | 2012-06-15 | 2014-01-01 | 北京中医药大学 | Antibody for detecting and determining berberine, and method and kit thereof |
| CN104996488A (en) * | 2015-07-14 | 2015-10-28 | 南京农业大学 | Insecticidal composition containing anhuiensis lycoris extract |
| CN105053052A (en) * | 2015-07-14 | 2015-11-18 | 南京农业大学 | Batrachium bungei extract containing insecticidal composition |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1233235C (en) * | 2001-08-15 | 2005-12-28 | 北京阳光露雨生物科技有限公司 | Aqueous berberine-matrine fungicidal and insecticidal solution |
| KR100691741B1 (en) * | 2005-04-07 | 2007-03-12 | 주식회사 비아이지 | Plant Extract Mixture Composition for Effective Control of Plant Powder |
-
2008
- 2008-11-14 CN CN2008101821560A patent/CN101422178B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103483444A (en) * | 2012-06-15 | 2014-01-01 | 北京中医药大学 | Antibody for detecting and determining berberine, and method and kit thereof |
| CN103444729A (en) * | 2013-09-05 | 2013-12-18 | 肇庆长龙生物科技有限公司 | Bactericidal pharmaceutical composition and applications thereof |
| CN104996488A (en) * | 2015-07-14 | 2015-10-28 | 南京农业大学 | Insecticidal composition containing anhuiensis lycoris extract |
| CN105053052A (en) * | 2015-07-14 | 2015-11-18 | 南京农业大学 | Batrachium bungei extract containing insecticidal composition |
| CN104996488B (en) * | 2015-07-14 | 2018-09-11 | 南京农业大学 | The Pesticidal combination of the extract of short-tube lycoris containing Anhui |
| CN105053052B (en) * | 2015-07-14 | 2019-03-01 | 南京农业大学 | The Pesticidal combination of aqueous ranunculus japonicus extract |
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|---|---|
| CN101422178B (en) | 2011-04-20 |
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