CN109090394A - A kind of preparation method preventing and treating four high low deuterium-oxide beverages - Google Patents
A kind of preparation method preventing and treating four high low deuterium-oxide beverages Download PDFInfo
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- CN109090394A CN109090394A CN201810916921.0A CN201810916921A CN109090394A CN 109090394 A CN109090394 A CN 109090394A CN 201810916921 A CN201810916921 A CN 201810916921A CN 109090394 A CN109090394 A CN 109090394A
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- oxide
- low deuterium
- lentinan
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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Abstract
The present invention provides a kind of preparation method for preventing and treating four high low deuterium-oxide beverages, methods are as follows: 1) prepare lentinan；2) soybean protein peptide hydrolysate is prepared；3) hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof are placed in low deuterium-oxide, boil and decoct 2-3h, obtains Chinese medicine extract；4) Chinese medicine extract by the preparation of lentinan, soybean protein peptide hydrolysate and step 3) mixes, and sterilizes up to four high low deuterium-oxide beverages are prevented and treated.Compared with prior art, the present invention is using low deuterium-oxide as one of primary raw material, control lentinan, the preparation process of Soyprotein peptide, design with hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof amount ratio, plurality of raw materials synergistic effect, can reach reducing blood lipid, hypoglycemic, blood pressure lowering, anti-trioxypurine, treat and prevent four high effects.
Description
Technical field
The invention belongs to the fields of health drink, and in particular to a kind of preparation for preventing and treating four high low deuterium-oxide beverages
Method.
Background technique
" three high " is the word that people often hear in life, so-called " three high ", that is, hypertension, hyperglycemia and height
Blood lipid.The current reduction with sports caused by the accelerating rhythm of life with the improvement of people ' s living standards, increasingly
More diseases, which is constantly ranked among, influences people's health, quality of life even the factor ranks of life, we must not no longer add one
It is high, that is, high lithemia.
In recent years, the disease incidence of high lithemia is in rising trend, moreover, high lithemia disease patient be often also associated with other " three
It is high ".
Dietotherapy is to adjust body function using the characteristic of food under instruction of Chinese Medicine theory, it is made to secure good health or more disease
A kind of method of diseases prevention.Generally, it is considered that food is various nutrients needed for providing growth and development and health existence for human body
Edibility substance.
In dietotherapy, in addition to food, water is even more most important.For people, water is the important object for being only second to oxygen
Matter.In adult body, 60~70% quality is water.The specific gravity of water is bigger in children's body, up to nearly 80%.If a people is not
It has a meal, only relies on the nutriment oneself stored in vivo or consumption autologous tissue, can live upper one month.But it if does not drink
Water, week age are also difficult to spend.Internal dehydration 10% just poses a health risk, and such as dehydration 20%, is just in peril of one's life.Therefore,
Water also plays very important importance in dietotherapy.
Existing water is generally made of 2 hydrogen atoms and 1 oxygen atom in nature, but hydrogen atom has different 3 of quality
A isotope, atomic weight amount are respectively 1,2,3 hydrogen (H), deuterium (D, heavy hydrogen), tritium (T, superheavy hydrogen).Studies at home and abroad show that weight
Hydrogen is harmful to the survival and development and procreation of life entity.
And deuterium hydrogen ratio is 150ppm in water in nature.Generally, the content of deuterium often uses water content lower than nature in water
The water of 150ppm is low deuterium-oxide.
Studies at home and abroad show that low deuterium-oxide there are many benefits to human health, it is relatively beneficial to the existence and procreation of life entity,
It is of great significance for the health of the mankind.Deuterium is harmful to the existence and procreation of life entity, and the low deuterium-oxide that amount containing deuterium is relatively low, tool
Have special molecular structure, molecule because diameter is half of light water, into life entity after have and absorb that fast, penetration is high, molten
The strong feature of power is solved, the substance of life entity can be effectively metabolized, receives nutritional benefit, excludes harmful substance.These situations are to animal
In this way, to plant in this way, being also such to the mankind.Therefore, the higher heavy water of amount containing deuterium is referred to as " water of death ", and amount containing deuterium
Lower low deuterium-oxide is then referred to as " water of life ".
Low deuterium-oxide is primarily present in the ice and snow of earth two-stage and high mountain, reduces the deuterium in Natural Water using ad hoc approach
It can get low deuterium-oxide.
For example publication number 101481088A applies for a kind of entitled " system of depleted water application No. is 200910046130.8
Method disclosed in the preparation method of standby device and depleted water " is prepared into the low deuterium-oxide of D abundance 2-105ppm.
Low deuterium-oxide is high in treatment four, and the prior art is rarely reported.
Summary of the invention
The purpose of the present invention is to provide a kind of preparation methods for preventing and treating four high low deuterium-oxide beverages, utilize low deuterium
Water decocts hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof, cooperation as solvent
Soybean small molecular protein peptide hydrolysate and lentinan, synergistic effect are conducive to anti-trioxypurine, reducing blood lipid, blood pressure lowering and hypoglycemic,
There are prevention and treatment to four height.
Specific technical solution of the present invention is as follows:
A kind of preparation method preventing and treating four high low deuterium-oxide beverages provided by the invention, comprising the following steps:
1) lentinan is prepared；
2) soybean protein peptide hydrolysate is prepared；
3) hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof are placed in low deuterium
In water, boils and decoct 2-3h, obtain Chinese medicine extract；
4) Chinese medicine extract by the preparation of lentinan, soybean protein peptide hydrolysate and step 3) mixes, and sterilizes up to pre-
Anti- and four high low deuterium-oxide beverages for the treatment of.
Step 1) the method for preparing lentinan are as follows:
After mushroom 1-1) crushed 150-200 sieve, it is placed in the low deuterium-oxide of 5-8 times of quality and impregnates 2-3h, then heat
To 85-95 DEG C, Microwave Extraction；
Step 1-1) 1-2) is extracted into system centrifugation, collects extracting solution, multigelation after centrifugation, collects supernatant liquor；
Sodium bicarbonate 1-3) is added into the supernatant liquor that step 1-2) is obtained, adjusts pH to 6-7, then, pancreas egg is added
White enzyme, heating water bath react 0.5-1h to 35-37 DEG C；It is then heated to 90-95 DEG C of heat preservation 30-50min, inactivates enzyme, from
The heart, filtering collect filtrate, obtain lentinan crude extract；
After 1-4) the polysaccharide crude extract of step 1-3) preparation is concentrated under reduced pressure, dehydrated alcohol sedimentation, centrifugation, mistake is added
Precipitating is collected in filter；
After 1-5) the low deuterium-oxide dissolution of 5-10 times of weight is added in precipitating, trifluoroacetic acid is added, heating hydrolysis, 40-60 DEG C true
Trifluoroacetic acid is received in backlash, obtains small molecule lentinan extracting solution；
1-6) small molecule lentinan extracting solution is concentrated, vacuum drying obtains lentinan.
Step 1-1) described in Microwave Extraction, under the conditions of referring to microwave power 400-500W, Microwave Extraction 1-2h.
Step 1-2) described in multigelation refer to: collect extracting solution after, after liquid to be extracted is cooled to room temperature, be placed in -18
It after freezing 4-8h under the conditions of~-20 DEG C, is placed in and dissolves at room temperature, be then centrifuged for, collect supernatant liquor, then be placed in -18~-20 DEG C
Under the conditions of freeze 4-8h after, be placed in and dissolve at room temperature, be then centrifuged for, collect supernatant liquor, repeat 3-5 times.
Step 1-3) in trypsase additional amount be supernatant quality 3-8%.
Step 1-4) described in be concentrated under reduced pressure refer to the 1/4-1/3 for being concentrated into original volume.
Step 1-4) described in addition dehydrated alcohol sedimentation specifically: 2-5 times of the volume of the concentrated liquid of ethyl alcohol, standing 4- is added
Precipitating is collected in 8h, centrifugation.
Step 1-5) in trifluoroacetic acid dosage be processing solution quality 1-2%.
Step 1-5) described in heating hydrolysis refer to and be heated under the conditions of 80-95 DEG C, hydrolyze 15-25min.
Step 2) the method for preparing soybean protein peptide hydrolysate are as follows:
2-1), it after drying soybean, grinds, crosses 300-400 mesh, obtain soy meal；
2-2), soy meal is added in low deuterium-oxide, adds papain, heating enzymatic hydrolysis；
2-3), it after enzyme deactivation, is centrifuged, filtering obtains soybean small molecular protein peptide hydrolysate.
Step 2-2) in, the solid-liquid ratio of soy meal and low deuterium-oxide is 1:20-30g/ml.The dosage of papain is soybean
The 0.5-0.8% of silty amount；Enzyme activity 5-8*105U/g。
Step 2-2) described in heating enzymatic hydrolysis refer to heating water bath to 50-60 DEG C, heat preservation enzymatic hydrolysis 40-60min.
Step 2-3) enzyme deactivation refers in 80-95 DEG C of heat preservation enzyme deactivation 15-20min.
Hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali, witloof and low deuterium in step 3)
The weight ratio of water is 3-5:1-2:0.5-1:0.3-1.2:2-3:0.2-0.8:1-2.1:1-2:1-1.8:0.8-1. 4:50-70.
Step 4), the mass ratio of the Chinese medicine extract of lentinan, soybean protein peptide hydrolysate and step 3) preparation: 0.5-
1:4-7:10-15.
Sterilize the 15-25min that sterilizes under the conditions of referring to 121 DEG C described in step 4).
Low deuterium-oxide is commercially available in the present invention, or utilizes publication number 101481088A, application No. is 200910046130.8,
Apply for that method disclosed in entitled " a kind of preparation facilities of depleted water and the preparation method of depleted water " is prepared into the low of 2-60ppm
Deuterium-oxide.
The present invention is in the method for preparing lentinan, using the characteristic of the low deuterium of glacial water, as Extraction solvent, alternatively,
The lower low deuterium-oxide of deuterium content is prepared using glacial water, since glacial water is rich in microelement, is conducive to the dissolution of lentinan
And extraction.In extraction process, low deuterium-oxide is heated, cooperates Microwave Extraction, is conducive to the extraction efficiency for improving polysaccharide, the extraction of polysaccharide
Rate is higher.After extraction, first multigelation removes protein and other impurities, and trypsase is recycled further to remove deproteinized
Matter improves the pick-up rate of polysaccharide, moreover, last alcohol sedimentation is primary, it can efficient removing protein.Finally, trifluoro is added
Lentinan is cut into micromolecular polysaccharide, is conducive to absorption of human body by acetic acid, improves its health value.With inhibit cancer cell,
Reducing blood lipid, it is hypoglycemic the effects of.Using the low deuterium-oxide of glacial water preparation as solvent, when preparing soybean small molecular protein peptide hydrolysate,
Using low deuterium-oxide as solvent, the enzyme solution and technological parameter of small molecular protein peptide are controlled, is conducive to the recovery rate for improving protein peptides
With the protein peptides for obtaining small-molecular-weight.
In the present invention, using low deuterium-oxide as primary raw material and extractant, low deuterium-oxide can significantly reduce fasting blood glucose level, be promoted
Fasting insulin level improves islet cells form, volume and distribution.Lentinan can adjust glycometabolism, mitigate diabetes
Symptom.Lentinan adjusts the activity of relevant enzyme, improves sugar, protein by promoting insulin secretion, improving insulin resistance
And fat metabolic disturbance, promote liver glycogen synthesis, inhibit gluconeogenesis, promotes a variety of ways such as function of immune system and antioxidation
Diameter plays function of blood sugar reduction.
The Soyprotein peptide of addition has apparent reduction to act on high cholesterol person, beneficial to human body highly dense without reducing
Spend cholesterol value.People normal for cholesterol also acts on without reduction, when they are in edible high-cholesterol diet, soybean egg
White peptide is also in the raising for preventing serum cholesterol.Moreover, Soyprotein peptide is by inhibiting Angiotensin-Converting activity
Effect, achieve the effect that angiotensins is prevented to convert, therefore the excess shrinkage of peripheral vessel can be prevented, reach blood pressure lowering
Effect.Its pressure reduction is steady, is not in drug decompression bring fluctuation feeling of pain caused by patient.To hypertension,
The patient of cardiovascular disease, especially primary hypertension patient have remarkable result.
In Chinese medicine extract, the root of straight ladybell contain saponin(e, can reducing blood lipid, promote blood circulation.Fructus lycii Chinese holly containing effective component
Qi polysaccharide can enhance the sensibility of insulin, while reducing blood glucose, moreover it is possible to prevent postprandial blood sugar from increasing；It can also reducing
Blood lipid and blood pressure.Corn stigma also can be hypoglycemic, treats diabetes.Campanulaceae not only has hypoglycemic effect, moreover it is possible to can alleviate diabetes
The dysphoria with smothery sensation of patient, thirsty symptom.Radix Astragali invigorating qi for strengthening superficies, diuresis toxin expelling, invigorating middle warmer and replenishing QI can treat diabetes and high lithemia.Mountain
Short, bristly hair or beard can reduce blood pressure, cholesterol, the effect for softening blood vessel and diuresis；Mulberry leaf, pueraria lobata, purslane and witloof are containing alkaloids
Class, triterpenes, sesquiterpenoids, synergistic effect can mediate uric acid with dispelling wind and removing obstruction in the meridians, activating blood circulation and reducing swelling, clearing away heat to and alleviating pain, anti-trioxypurine.
Compared with prior art, the present invention controls lentinan using low deuterium-oxide as one of primary raw material, Soyprotein peptide
Preparation process, design with hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof dosage
Than plurality of raw materials synergistic effect can reach reducing blood lipid, hypoglycemic, blood pressure lowering, anti-trioxypurine, treat and prevent four high effects.
Specific embodiment
Embodiment 1
A kind of preparation method preventing and treating four high low deuterium-oxide beverages, comprising the following steps:
1) lentinan, is prepared:
1-1), it after mushroom crushed 200 sieves, is placed in the low deuterium-oxide of 7 times of quality and impregnates 2.5h, be then heated to 90
DEG C, under the conditions of microwave power 400W, Microwave Extraction 1h；
1-2), step 1-1) is extracted into system centrifugation, collects extracting solution and is placed in -18 after liquid to be extracted is cooled to room temperature
It after freezing 5h under the conditions of~-20 DEG C, is placed in and dissolves at room temperature, be then centrifuged for, collect supernatant liquor, repeat the above steps 4 times, from
After the heart, supernatant liquor is collected；
1-3), sodium bicarbonate is added into the supernatant liquor that step 1-2) is obtained, adjusts pH to 6.5, then, supernatant is added
3.5% trypsase of liquid quality, heating water bath react 1h to 37 DEG C；95 DEG C of heat preservation 40min are then heated to, enzyme is lost
It is living, it is then centrifuged for, filters, collect filtrate, obtain lentinan crude extract；
1-4), after step 1-3) the polysaccharide crude extract prepared being concentrated under reduced pressure into the 1/4 of original volume, concentrate is added
The dehydrated alcohol sedimentation that 3 times of volume, is centrifuged, and precipitating is collected in filtering；
1-5), after the low deuterium-oxide dissolution of 6 times of weight is added in precipitating, 1.5% trifluoro second of the quality of the solution of processing is added
Acid is heated under the conditions of 95 DEG C, hydrolyzes 20min, and then, 60 DEG C of vacuum recycle trifluoroacetic acid, is obtained small molecule lentinan and is mentioned
Take liquid；
1-6), small molecule lentinan extracting solution is concentrated, vacuum drying obtains lentinan.
2) soybean protein peptide hydrolysate is prepared:
2-1), it after drying soybean, grinds, crosses 400 meshes, obtain soy meal；
2-2), soy meal is added in low deuterium-oxide, the solid-liquid ratio of soy meal and low deuterium-oxide is 1:25g/ml, adds pawpaw
Protease, the dosage of papain are the 0.6% of soy meal quality；Enzyme activity 8*105U/g, heating water bath is to 60 DEG C, heat preservation
Digest 40min；
2-3), it after 95 DEG C of heat preservation enzyme deactivation 15min, is centrifuged, filtering obtains soybean small molecular protein peptide hydrolysate.
3) hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof, are placed in low deuterium
In water, hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali, witloof and low deuterium-oxide weight ratio
For 3.3:1.2:0.6:0.5:2.2:0.4:1.4:1.2:1.2:0.9:60, boils and decoct 2h, obtain Chinese medicine extract；
4) by the Chinese medicine extract of lentinan, soybean protein peptide hydrolysate and step 3) preparation according to mass ratio: 0.6:
5:12 is mixed, and sterilizing 20min is under the conditions of 121 DEG C to get four high low deuterium-oxide beverages of prevention and treatment.
Embodiment 2
A kind of preparation method preventing and treating four high low deuterium-oxide beverages, comprising the following steps:
1) lentinan is prepared:
It after mushroom 1-1) crushed 180 sieves, is placed in the low deuterium-oxide of 8 times of quality and impregnates 3h, be then heated to 95 DEG C, it is micro-
Under the conditions of wave power 400W, Microwave Extraction 1h；
Step 1-1) 1-2) is extracted into system centrifugation, collects extracting solution, after liquid to be extracted is cooled to room temperature, it is placed in -18~-
It after freezing 7h under the conditions of 20 DEG C, is placed in and dissolves at room temperature, be then centrifuged for, supernatant liquor is collected, after being repeated 5 times centrifugation, in collection
Layer clear liquid；
Sodium bicarbonate 1-3) is added into the supernatant liquor that step 1-2) is obtained, adjusts pH to 6, then, supernatant is added
4.5% trypsase of quality, heating water bath react 0.6h to 37 DEG C；92 DEG C of heat preservation 40min are then heated to, enzyme is lost
It is living, it is centrifuged, filtering collects filtrate, obtains lentinan crude extract；
After step 1-3) the polysaccharide crude extract prepared 1-4) is concentrated under reduced pressure into the 1/4 of original volume, concentrate is added
The dehydrated alcohol sedimentation that 4 times of volume, is centrifuged, and precipitating is collected in filtering；
After 1-5) the low deuterium-oxide dissolution of 8 times of weight is added in precipitating, 1.5% trifluoro second of the quality of the solution of processing is added
Acid is heated under the conditions of 85 DEG C, hydrolyzes 25min, and 50 DEG C of vacuum recycle trifluoroacetic acid, obtain small molecule lentinan extracting solution；
1-6) small molecule lentinan extracting solution is concentrated, vacuum drying obtains lentinan.
2) soybean protein peptide hydrolysate is prepared:
It after 2-1) drying soybean, grinds, crosses 400 meshes, obtain soy meal；
2-2) soy meal is added in low deuterium-oxide, the solid-liquid ratio of soy meal and low deuterium-oxide is 1:30g/ml, adds pawpaw
Protease, the dosage of papain are the 0.7% of soy meal quality；Enzyme activity 5*105U/g, heating water bath is to 55 DEG C, heat preservation
Digest 45min；
It 2-3) after 95 DEG C of heat preservation enzyme deactivation 15min, is centrifuged, filtering obtains soybean small molecular protein peptide hydrolysate.
3) hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof are placed in low deuterium
In water, hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali, witloof and low deuterium-oxide weight ratio
For 4:1.8:0.8:0.9:2.8:0.6:1.8:1.5:
3h is decocted 1.5:1.1:70 boiling, obtains Chinese medicine extract；
4) by the Chinese medicine extract of lentinan, soybean protein peptide hydrolysate and step 3) preparation according to mass ratio: 1:6:
15 mix, and sterilizing 25min is under the conditions of 121 DEG C to get four high low deuterium-oxide beverages of prevention and treatment.
The high low deuterium-oxide beverage of prevention and treatment four prepared by embodiment 1, there is 83 four high different age group different sexes
Patient voluntarily drink, 2 times a day, each 250ml, after continuously drinking 1 month, 68 four height of patient are substantially reduced, and have treatment
Effect；3 patients four are high not to reduce；It is high that 12 patients cure four.
The high low deuterium-oxide beverage of prevention and treatment four prepared by embodiment 2, there is 91 four high different age group different sexes
Patient voluntarily drink, 2 times a day, each 250ml, after continuously drinking 1 month, 75 four height of patient are substantially reduced, and have treatment
Effect；2 patients four are high not to reduce；It is high that 14 patients cure four.
Claims (10)
1. it is a kind of prevent and treat four high low deuterium-oxide beverages preparation method, which is characterized in that the preparation method include with
Lower step:
1) lentinan is prepared；
2) soybean protein peptide hydrolysate is prepared；
3) hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, pueraria lobata, purslane, fructus lycii, corn stigma, Radix Astragali and witloof are placed in low deuterium-oxide,
It boils and decocts 2-3h, obtain Chinese medicine extract；
4) by lentinan, soybean protein peptide hydrolysate and step 3) preparation Chinese medicine extract mix, sterilize up to prevention and
Treat four high low deuterium-oxide beverages.
2. preparation method according to claim 1, which is characterized in that the step 1) method for preparing lentinan are as follows:
After mushroom 1-1) crushed 150-200 sieve, it is placed in the low deuterium-oxide of 5-8 times of quality and impregnates 2-3h, be then heated to 85-
95 DEG C, Microwave Extraction；
Step 1-1) 1-2) is extracted into system centrifugation, collects extracting solution, multigelation after centrifugation, collects supernatant liquor；
Sodium bicarbonate 1-3) is added into the supernatant liquor that step 1-2) is obtained, adjusts pH to 6-7, then, trypsase is added,
Heating water bath reacts 0.5-1h to 35-37 DEG C；It is then heated to 90-95 DEG C of heat preservation 30-50min, inactivates enzyme, is centrifuged, mistake
Filter collects filtrate, obtains lentinan crude extract；
After 1-4) the polysaccharide crude extract of step 1-3) preparation is concentrated under reduced pressure, dehydrated alcohol sedimentation is added, is centrifuged, filters, receives
Collection precipitating；
After 1-5) the low deuterium-oxide dissolution of 5-10 times of weight is added in precipitating, trifluoroacetic acid, heating hydrolysis is added, 40-60 DEG C of vacuum is returned
Trifluoroacetic acid is received, small molecule lentinan extracting solution is obtained；
1-6) small molecule lentinan extracting solution is concentrated, vacuum drying obtains lentinan.
3. preparation method according to claim 2, which is characterized in that step 1-1) described in Microwave Extraction, refer to microwave
Under the conditions of power 400-500W, Microwave Extraction 1-2h.
4. preparation method according to claim 2, which is characterized in that step 1-3) in trypsase additional amount be supernatant
The 3-8% of liquid quality.
5. preparation method according to claim 2, which is characterized in that step 1-5) in trifluoroacetic acid dosage be processing
The 1-2% of the quality of solution；The heating hydrolysis, which refers to, to be heated under the conditions of 80-95 DEG C, and 15-25min is hydrolyzed.
6. preparation method according to claim 1, which is characterized in that step 2) is described to prepare soybean protein peptide hydrolysate
Method are as follows:
2-1), it after drying soybean, grinds, crosses 300-400 mesh, obtain soy meal；
2-2), soy meal is added in low deuterium-oxide, adds papain, heating enzymatic hydrolysis；
2-3), it after enzyme deactivation, is centrifuged, filtering obtains soybean small molecular protein peptide hydrolysate.
7. preparation method according to claim 6, which is characterized in that step 2-2) in, the feed liquid of soy meal and low deuterium-oxide
Than for 1:20-30g/ml.
8. preparation method according to claim 6, which is characterized in that step 2-2) in, the dosage of papain is big
The 0.5-0.8% of bean powder quality；Enzyme activity 5-8*105U/g。
9. preparation method according to claim 6, which is characterized in that hawthorn, the root of straight ladybell, campanulaceae, mulberry leaf, Pueraria lobota in step 3)
Root, purslane, fructus lycii, corn stigma, Radix Astragali, witloof and low deuterium-oxide weight ratio be 3-5:1-2:0.5-1:0.3-1.2:2-3:
0.2-0.8:1-2.1:1-2:1-1.8:0.8-1.4:50-70。
10. preparation method according to claim 6, which is characterized in that step 4), lentinan, soybean protein hydrolase polypeptide
The mass ratio of liquid and the Chinese medicine extract of step 3) preparation: 0.5-1:4-7:10-15.
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