CN105031130A

CN105031130A - Traditional Chinese medicine for treating central retinal vein occlusion

Info

Publication number: CN105031130A
Application number: CN201510527737.3A
Authority: CN
Inventors: 何萍萍
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-08-25
Filing date: 2015-08-25
Publication date: 2015-11-11

Abstract

The invention relates to a traditional Chinese medicine for treating central retinal vein occlusion, which is prepared from the following raw medicines in parts by weight: 10 parts of Carex scaposa C.B.Clarke, 15 parts of long stephania herb, 9 parts of gymnogongrus flabelliformis, 15 parts of roundleaf dutchmanspipe root, 30 parts of potentilla limprichtii, 12 parts of rungia pectinata and 25 parts of nettle. Clinical experiments prove that the traditional Chinese medicine provided by the invention can be used for safely and effectively treating central retinal vein occlusion.

Description

A kind of Chinese medicine being used for the treatment of central retinal vein occlusion

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of central retinal vein occlusion.

Background technology

Central retinal vein occlusion is more common retinal vascular disease, is also one of retinopathy of blinding.Be more common in Middle Age and Aged Patients, normal simple eye morbidity, vision sharply declines, and often with pathological changes such as hypertension, arteriosclerosis, diabetes, hyperlipidemia, men and women's zero difference is often simple eye morbidity, and eyes morbidity is less.The traditional Chinese medical science is thought, the generation of primary disease, the many and seven emotions of its cause of disease, and diet, fatigue, calentura phlegm-fire are relevant.Its pathogenesis according to clinical findings, how because of excessive rising of liver-YANG, upward invasion of liver-QI; Or stagnation of QI due to depression of the liver, the blood stasis of blood is stagnant; Or expectorant Re Neisheng, upper heap soil or fertilizer over and around the roots order key; Or overabundant liver-fire, above attack in order; Or hyperactivity of fire caused by deficiency of YIN, above disturb key clearly, cause order median nexus obstruction and send out as primary disease.If lose and control wrong treatment, the later stage can cause the atrophy of order system, even becomes other oculopathy raw.The outer disease of primary disease eye is less, internal examination of eye and subjective symptoms should be combined, and dialectical in conjunction with whole body arteries and veins card, its card has void to have reality, but no matter deficiency syndrome, excess syndrome are all stagnant relevant with the venation stasis of blood.If primary disease intraocular hemorrhage is more, can secondary glaucoma.Later stage causes the atrophy of order system, macula lutea Blessing's cysts, vision serious hindrance.

Medical material present Research involved in the present invention is as follows:

Overturn the heavens red [another name] land Scolopendra.[source] medical material Ji Yuan: be the grass of sedge Carex scaposa C. B. Clarke.Gather and store: summer, autumn gather, clean, using fresh herb or cutting are dried.[nature and flavor] bitter in the mouth; Cold in nature.[return through] returns stomach through, kidney channel.[function cures mainly] heat-clearing and toxic substances removing; Promoting blood circulation to remove blood stasis.Main acute gastroenteritis; Traumatic injury; Blood stasis is had a pain; Lumbar muscle strain.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[extracts] " China's book on Chinese herbal medicine ".

Herba Stephaniae Longae [another name] Ha Soft-Fleece grass, Rana nigromaculata careless, Lei Portland mouth, dustpan grass, flying apsaras Thunder God, mouldboard rattan, iron plate plaster grass.The herb that [source] is menispermaceous plants Herba Stephaniae Longae or rhizome and root.The whole year can adopt.Generally how to extract rattan leaf in the fall or to grub out and get, wash away silt particle, removing radicula, dries or using fresh herb.[nature and flavor] taste raw meat, property is put down.Hardship, cold.[return through] returns liver; Gallbladder; Large intestine channel.[function cures mainly] heat-clearing and toxic substances removing, dampness removing relieving constipation, the skin ulcer that disappears swells.Control calentura to go mad, jaundice, gastroenteritis, dysentery, constipation, hematuria, sore and toxic.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] deficiency of YIN cough caused by dryness and chronic cough deficiency of vital energy person should not take.[extracts] " China's book on Chinese herbal medicine ".

Fork branch algae [another name] silk algae, cartilage red algae, flat fork branch algae, bar, Carnis Haliotidis dish, Herba Salsolae Collinae.[source] is the frond of Phyllophoraceae plant fork branch algae, gathers and stores: spring, summer, autumn pluck, and clean and dry.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.The spleen invigorating of soil fork branch algae, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[extracts] " China's book on Chinese herbal medicine ".

Fructus Aristolochiae Kwangsiensis [another name] Radix Raphani Radix Stephaniae Tetrandrae, Aristolochia koempeferi, roundleaf Fructus Aristolochiae, gold silver bag, great Ye mountain house steward, Radix Aristolochiae, Fructus Aristolochiae Kwangsiensis.[source] Aristolochiaceae birthwort kwangsi dutchmanspipe root is used as medicine with root.The whole year can adopt, and cleans and dries.[nature and flavor] sweet, bitter, cold.[return through] returns stomach warp.[function cures mainly] heat-clearing and toxic substances removing, regulating QI to relieve pain, cooling blood for hemostasis.For acute gastroenteritis, taste-blindness rate, pharyngolaryngitis, pulmonary tuberculosis, traumatic injury; Traumatic hemorrhage is controlled in external, carbuncle pyogenic infections from tumour or sore.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[attention] Fructus Aristolochiae Kwangsiensis is cold in nature, and deficient cold type dysmenorrhea, amenorrhea avoid use.[extracts] " China's book on Chinese herbal medicine ".

Potentilla sericea L.(Potentilla poteroides Franch) [source] medical material Ji Yuan: be the herb of rosaceous plant lower reaches of the Changjiang River Herba Potentillae Chinensis.Gather and store: spring, summer excavate, cleaning, dry.[nature and flavor] are sweet; Temperature.[return through] kidney channel.[function cures mainly] strengthening spleen, tonifying kidney, arresting sweating, hemostasis.Main weakness due to chronic disease, night sweat due to yin deficiency, metrorrhagia, leukorrhagia.[usage and dosage] takes orally: decoct soup, 30 ~ 60g.[extracts] " China's book on Chinese herbal medicine ".

Herba rungiae pectinatae [another name] blueness is careless, by first grass, Huang Fengcao, sub-brother profit, red nose king, Linesless charcoal grass, four directions stalk, fish tail grass, JIYAOCAO, the replacement of soil summer is careless, infantile malnutrition is careless.[source] medical material Ji Yuan: be the herb of acanthaceous plant Herba rungiae pectinatae.Gather and store: summer, autumn, winter gather, cleaning, fresh victory or dry.[nature and flavor] mildly bitter flavor; Pungent; Cool in nature.[return through] lung; Liver; Spleen channel.[function cures mainly] removing food stagnancy is stagnant; Removing fire from the liver; Clearing away damp-heat.Main food stagnation of child; Conjunctival congestion and swelling pain; Damp-heat dysentery; Hepatitis; Scrofula carbuncle; Venom.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".

Herba Girardiniae Palmatae [another name] a lot of money fiber crops, stalk fiber crops, numb, the Herba Urticae Cannabinae of money, Sedum spectabile Boreau.The herb that [source] is contrayerva Herba Girardiniae Palmatae or root.The whole year can adopt.Dry or using fresh herb.[nature and flavor] toil, cool.[return through] returns lung meridian.[function cures mainly] expelling pathogenic wind from the body surface, promoting the circulation of QI expectorant, Qinghuo Jiedu.Control the cough due to common cold, abundant expectoration uncomfortable in chest, skin is itched, sore.[usage and dosage] takes orally: decoct soup, 25 ~ 50g.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of central retinal vein occlusion, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing central retinal vein occlusion.

In order to achieve the above object, the present invention is by the following technical solutions:

A kind of Chinese medicine being used for the treatment of central retinal vein occlusion, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: overturn the heavens red 10 parts, Herba Stephaniae Longae 15 parts, 9 parts, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 parts, Potentilla sericea L.(Potentilla poteroides Franch) 30 parts, Herba rungiae pectinatae 12 parts, Herba Girardiniae Palmatae 25 parts.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Outpatient service is collected and patients with central retinal vein occlusion 186 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 93 example and matched group 93 example at random, treatment group man 57 example, female 36 example, 10 ~ 82 years old age, 43 years old mean age; Matched group man 41 example, female 52 example, 12 ~ 78 years old age, 37.5 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

Diagnostic criteria according to the meeting of national central retinal vein occlusion clinical speciality:

(1), hypertension, diabetic history.

(2), visual deterioration, as involved macula area vision light sensation, even blind.

(3), central vein of the retina thromboembolism time, venous engorgement, aubergine, retinal edema, large stretch of hemorrhage radially, flamboyancy or round shape, and adularescent cotton wool exudate, the hemorrhage vitreous body that enters causes muddiness.During as branch's thromboembolism, hemorrhage only for domination position.Papilloedema, edge blurry, there is ecchymosis on surface.

(4), connective tissue proliferation and new vessels can be formed after hemorrhage and exudate absorption, cause proliferative retinopathy and secondary glaucoma.

(5), fluoroscopic visualization: peripheral veins visible fluorescence seepage, venous perfusion is slow or incomplete, and hemorrhage district fluorescence hides, and late period can occur Doppler flow mapping.

2, test method

2.1 Therapeutic Method

The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.4 weeks courses for the treatment of.

Matched group external urokinase, quiet of 500 ~ 10000U liquid feeding once a day, is for 10 times a course for the treatment of; Oral bendazol 20mg, every day 3 times; Niacinamide usp 0.1g, every day 3 times.4 weeks courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Cure: optical fundus blood circulation improves, retinal hemorrhage basic absorption, and vision is promoted;

Effective: retinal hemorrhage partially absorbs, vision slightly takes a turn for the better;

Invalid: symptom is without improvement or increase the weight of.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Visible, the medicine that the present invention obtains can safe and effective treatment central retinal vein occlusion, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: overturn the heavens red 10 grams, Herba Stephaniae Longae 15 grams, 9 grams, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 grams, Potentilla sericea L.(Potentilla poteroides Franch) 30 grams, Herba rungiae pectinatae 12 grams, Herba Girardiniae Palmatae 25 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of central retinal vein occlusion.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 2

Take: overturn the heavens red 10 grams, Herba Stephaniae Longae 15 grams, 9 grams, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 grams, Potentilla sericea L.(Potentilla poteroides Franch) 30 grams, Herba rungiae pectinatae 12 grams, Herba Girardiniae Palmatae 25 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Embodiment 3

Take: overturn the heavens red 10 grams, Herba Stephaniae Longae 15 grams, 9 grams, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 grams, Potentilla sericea L.(Potentilla poteroides Franch) 30 grams, Herba rungiae pectinatae 12 grams, Herba Girardiniae Palmatae 25 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Claims

1. one kind is used for the treatment of the Chinese medicine of central retinal vein occlusion, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: overturn the heavens red 10 parts, Herba Stephaniae Longae 15 parts, 9 parts, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 parts, Potentilla sericea L.(Potentilla poteroides Franch) 30 parts, Herba rungiae pectinatae 12 parts, Herba Girardiniae Palmatae 25 parts.

2. a kind of Chinese medicine being used for the treatment of central retinal vein occlusion as claimed in claim 1, it is characterized in that, its preparation method is: take: overturn the heavens red 10 parts, Herba Stephaniae Longae 15 parts, 9 parts, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 parts, Potentilla sericea L.(Potentilla poteroides Franch) 30 parts, Herba rungiae pectinatae 12 parts, Herba Girardiniae Palmatae 25 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.

3. a kind of Chinese medicine being used for the treatment of central retinal vein occlusion as claimed in claim 1, it is characterized in that, its preparation method is: take: overturn the heavens red 10 parts, Herba Stephaniae Longae 15 parts, 9 parts, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 parts, Potentilla sericea L.(Potentilla poteroides Franch) 30 parts, Herba rungiae pectinatae 12 parts, Herba Girardiniae Palmatae 25 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.

4. a kind of Chinese medicine being used for the treatment of central retinal vein occlusion as claimed in claim 1, it is characterized in that, its preparation method is: take: overturn the heavens red 10 parts, Herba Stephaniae Longae 15 parts, 9 parts, fork branch algae, Fructus Aristolochiae Kwangsiensis 15 parts, Potentilla sericea L.(Potentilla poteroides Franch) 30 parts, Herba rungiae pectinatae 12 parts, Herba Girardiniae Palmatae 25 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.