CN104721591A - Traditional Chinese medicine for treating migraine - Google Patents
Traditional Chinese medicine for treating migraine Download PDFInfo
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- CN104721591A CN104721591A CN201510151117.4A CN201510151117A CN104721591A CN 104721591 A CN104721591 A CN 104721591A CN 201510151117 A CN201510151117 A CN 201510151117A CN 104721591 A CN104721591 A CN 104721591A
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Abstract
The invention relates to a traditional Chinese medicine for treating migraine. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 25 parts of ligusticum wallichii, 10 parts of the root of kudzu vine, 9 parts of corydalis tuber, 9 parts of the root of bidentate achyranthes, 9 parts of lumbricus, 3 parts of asarum, 9 parts of radix angelicae, 9 parts of gastrodia elata, and 10 parts of uncaria. Clinical experiments prove that the traditional Chinese medicine disclosed by the invention is capable of treating migraine safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to one and be used for the treatment of migrainous Chinese medicine.
Background technology
Migraine be a class ictal and normal be one-sided pulsatile headache.In the U.S., the social economical burden that migraine causes is 10 ~ 1,700,000,000 dollars.Also a large amount of patient is had to affect work, studying and living because of migraine in China.Most of patients has family history.Headache can come across any position around head or cervical region, can temporo side, position, forehead, pars orbitalis.Mostly be hemialgia, also can be bilateral pain, even develop into full headache, wherein hemialgia person accounts for 2/3.Headache character is often throbbing pain, but the patient also had is described as drilling pain.Pain degree be often in, severe pain, be even difficult to stand.Play sequela morning often, develop gradually, alleviate gradually after reaching peak.Migraine aura can not occur by companioned with headache, is called Migraine equivalents.Be more common in Children with Migraine.Sometimes see after the middle age, tendency can be the main clinical manifestation of migraine and very light or no headache of having a headache.Also alternately can occur with Headache attacks, can show as that flash of light, dim spot, stomachache, diarrhoea, Nausea and vomiting, recurrent are dizzy, hemiplegia, hemianesthesia and psychiatric change.As benign childhood episodic vertigo, vestibular Meniere, adult's benign recurrent vertigo.Have follow-up study to show, quite a lot patients being in the past diagnosed as Meniere, its symptom great majority are relevant with migraine.
Medical material present Research involved in the present invention is as follows:
Rhizoma Chuanxiong [another name] rhizome of chuanxiong Qiong, Rhizoma Chuanxiong.[source] this product is the dry rhizome of samphire Rhizoma Chuanxiong.Summer shows outstanding when joint dish on stem, and excavates during purplish, and removing silt, after shining, a heatable brick bed is done, then removes fibrous root.[nature and flavor] are pungent, temperature.[return through] returns liver, gallbladder, pericardium channel.[function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.[usage and dosage] takes orally: decoct soup, 9 ~ 25g.[attention] hyperactivity of fire caused by deficiency of YIN, upper excess and lower deficiency and the weak people of gas avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
Radix Puerariae [another name] Pueraria lobata, Pachyrhizua angulatus, Radix puerariae, Pueraria montana (Lour.) Merr. rattan.[source] this product is the dry root of legume pueraria lobata or Radix Puerariae rattan.Autumn, season in winter two excavate, and Herba Gelsemii Elegantis takes advantage of fresh-cut more and becomes sheet or fritter; Dry; Radix Puerariae rattan is practised and claims " Pachyrhizua angulatus ", removes crust more, after smoked with sulfur, slightly dry, and intercept or again rip cutting two halves are dry.[nature and flavor] are sweet, pungent, cool.[return through] returns spleen, stomach warp.[function cures mainly] expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] can not take more, and probably damages gastric qi.Summer, exterior deficiency hyperhidrosis was avoided especially.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Corydalis [another name] Rhizoma Corydalis element, Rhizoma Corydalis, Rhizoma Corydalis.[source] this product is the dry tuber of papaveraceae plant corydalis.Excavate when early summer stem and leaf is withered, removing fibrous root, cleans, and puts in boiling water and boils to during just without the white heart, take out, dry.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, spleen channel.[function cures mainly] invigorates blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.[usage and dosage] takes orally: decoct soup, 3-9g.[attention] anemia of pregnant woman is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Radix Achyranthis Bidentatae [another name] Radix Achyranthis Bidentatae, cattle condyle knee joint, Herba Ophiorrhizae pumilae, Twotooth Achyranthes Root, Red Radix Achyranthis Bidentatae, Du's Radix Achyranthis Bidentatae, Radix Achyranthis [wild product].[source] this product is the dry root of amaranthaceous plant Radix Achyranthis Bidentatae.Excavate when winter, stem and leaf was withered, removing fibrous root and silt, be bundled into wisp, shine to shriveling, trimmed on top, dry.[nature and flavor] are bitter, sour, flat.[return through] returns liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] anemia of pregnant woman is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Pheretima [another name] Lumbricus, cricket earthworm, bent worm, native Dan, red worm.[source] this product is the dry body of Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, power simulation or the blind Pheretimatschiliensis of comb.Front one is practised and is claimed " LUMBRICUS ", practises title " Shanghai Pheretima " for latter three kinds.LUMBRICUS catches to autumn spring, and Shanghai Pheretima catches summer, cuts abdominal part open in time, and removing internal organs and silt are cleaned, dried or cold drying.[nature and flavor] are salty, cold.[return through] returns liver, spleen, urinary bladder channel.[function cures mainly] heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.[usage and dosage] takes orally: decoct soup, 4.5-9g.[attention] Deficiency and coldness of spleen and stomach should not take, and anemia of pregnant woman prohibits clothes.[extracts] " China's book on Chinese herbal medicine ".
Herba Asari [another name] little Xin, Herba Ceratophylli Demeersi, few pungent, Kingdonia uniflora, Jin Pencao, Shan Rencan.[source] this product is the dry herb of aristolochiaceae plant Herba Asari, Seoul Herba Asari or magnificent Herba Asari.The first two is planted to practise and claims " Herba Asari ".Summer fructescence or excavate early autumn, removing silt, dries in the shade.[nature and flavor] are pungent, temperature.[return through] GUIXIN, lung, kidney channel.[function cures mainly] expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.[usage and dosage] takes orally: decoct soup, 1 ~ 3g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.[extracts] " China's book on Chinese herbal medicine ".
The Radix Angelicae Dahuricae [another name] Xue, the root of Dahurian angelica, fragrance, the membrane inside the rush stalk Li, Ze Fen, white Chai, Radix Angelicae Dahuricae (Radix Heraclei Scabridi).[source] this product is the dry root of the umbellate form section plant Radix Angelicae Dahuricae or Radix angelicae dahuricae.Excavate when between summer, autumn, leaf is yellow, removing fibrous root and silt, dry or cold drying.[nature and flavor] are pungent, temperature.[return through] returns stomach, large intestine, lung meridian.[function cures mainly] loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] YinXuXueRe person avoids clothes.Radix Angelicae Sinensis makes for it.Dislike Flos Inulae.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Gastrodiae [another name] rhizoma gastrodiae, Mokpo, RHIZONA GASTRODIAE, subduing the wind syndrome grass roots, Bai Longpi.[source] this product is the dry tuber of orchid Rhizoma Gastrodiae.Excavate as " spring fiber crops " between 4 ~ May of spring; What excavated between 9 ~ October before the Beginning of Winter is " winter fiber crops ", and quality is better.Take advantage of after having dug and freshly wash away earth, with clear water or Alumen water slightly bubble, scrape off crust, decocting in water or steam the heart, section, spreads out and dries.[nature and flavor] are sweet, flat.[return through] returns Liver Channel.[function cures mainly] suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Dizzy for having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] makes imperial wind grass roots, does not make Rhizoma Gastrodiae, if two same use, has namely made us the trouble of intestinal knot.[extracts] " China's book on Chinese herbal medicine ".
Ramulus Uncariae Cum Uncis [another name] Ramulus Uncariae macrophyllae, Wang Gambirplant Branchlet, hang wind root, golden hook grass, reversal of the natural order of things thorn.[source] this product is the dry stem and branch with belt hook of Maguireothamnus speciosus Ramulus Uncariae Cum Uncis, Ramulus Uncariae macrophyllae, Ramulus Uncariae Cum Uncis, Uncaria sinensis (Oliv.) Havil. or stockless fruit Ramulus Uncariae Cum Uncis.Autumn, season in winter two gather, and defoliation, cutting, dries.[nature and flavor] are sweet, cool.[return through] returns liver, pericardium channel.[function cures mainly] heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.Dizzy for having a headache, dysphoric cold, infantile convulsion is twitched, pre-eclampsia; Hypertension.[usage and dosage] takes orally: decoct soup, 3 ~ 12g.[attention] can steal gas, and empty person does not throw.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide one and is used for the treatment of migrainous Chinese medicine, by selecting suitable medical material and proportioning thereof, reaches the migrainous object of safe and effective healing.
In order to achieve the above object, the present invention is by the following technical solutions:
One is used for the treatment of migrainous Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Chuanxiong 25 parts, Radix Puerariae 10 parts, Rhizoma Corydalis 9 parts, Radix Achyranthis Bidentatae 9 parts, Pheretima 9 parts, Herba Asari 3 parts, the Radix Angelicae Dahuricae 9 parts, 9 parts, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and migraineur 92 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 46 example and matched group 46 example at random, treatment group man 25 example, female 21 example, 40 years old mean age; Matched group man 23 example, female 23 example, 45 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national migraine clinical speciality: clinical cardinal symptom is headache recurrent exerbation, can continue 4 more than h at every turn, have a headache based on one-sided or bilateral pulsation, pain gesture is long, when time is done only, severe one is shown in dizziness, nauseating, poor appetite, photophobia and phonophobia etc.Every adjunct test confirms without organic disease, side by side except the headache caused by wound, inflammation and other diseases.Tcm diagnosis standard is had a headache: cephalic pain, dizziness, complexion be dark, uncomfortable in chest, coerce swollen, dryness of the mouth and thirst, purplish tongue, tongue body ecchymosis, yellow and thin fur, thready and stringy pulse.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 2 times.1 month course for the treatment of.
The oral XIBILING JIAONANG of matched group, sleeps first 1,10 days courses for the treatment of every night.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect stage of attack therapeutic evaluatioies
Cure: in medication 24h, pain disappears, in 48h, headache is without again occurring;
Effective: in medication 24h, headache syndromes is relieved to slightly from moderate, severe, maintain pain relief in 48h;
Invalid: in medication 72h, headache is without obviously alleviating.
3.2 criterion of therapeutical effect prophylactic treatment therapeutic evaluatioies
Utilize the classification of headache every 4 weeks average attack times, every 4 weeks average headache days and headache degree before and after the treatment of headache journal record, and judge curative effect according to integration method.
Clinic control: the improvement of clinical symptoms, somatic feature score is greater than more than 95%.
Effective: clinical symptoms, somatic feature score improve and be greater than 75% and be less than 90%.
Effective: clinical symptoms, somatic feature score improve and be greater than 30% and be less than 70%.
Invalid: the improvement of clinical symptoms, somatic feature score is less than 30%.
3.3 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
| Group | n | Clinic control | Effective | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction example |
| Treatment group | 46 | 18 | 9 | 13 | 6 | 86.95% | 0 |
| Matched group | 46 | 13 | 8 | 10 | 15 | 67.39% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment migraine, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Rhizoma Chuanxiong 25 grams, Radix Puerariae 10 grams, Rhizoma Corydalis 9 grams, Radix Achyranthis Bidentatae 9 grams, Pheretima 9 grams, Herba Asari 3 grams, the Radix Angelicae Dahuricae 9 grams, 9 grams, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of migraine.Oral, every bu is taken for twice sooner or later.
Embodiment 2
Take: Rhizoma Chuanxiong 25 grams, Radix Puerariae 10 grams, Rhizoma Corydalis 9 grams, Radix Achyranthis Bidentatae 9 grams, Pheretima 9 grams, Herba Asari 3 grams, the Radix Angelicae Dahuricae 9 grams, 9 grams, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of migraine.Oral, every bu is taken for twice sooner or later.
Embodiment 3
Take Rhizoma Chuanxiong 25 grams, Radix Puerariae 10 grams, Rhizoma Corydalis 9 grams, Radix Achyranthis Bidentatae 9 grams, Pheretima 9 grams, Herba Asari 3 grams, the Radix Angelicae Dahuricae 9 grams, 9 grams, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of migraine.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of migrainous Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Chuanxiong 25 parts, Radix Puerariae 10 parts, Rhizoma Corydalis 9 parts, Radix Achyranthis Bidentatae 9 parts, Pheretima 9 parts, Herba Asari 3 parts, the Radix Angelicae Dahuricae 9 parts, 9 parts, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 parts.
2. as claimed in claim 1 for migrainous Chinese medicine, it is characterized in that, its preparation method is: take: Rhizoma Chuanxiong 25 parts, Radix Puerariae 10 parts, Rhizoma Corydalis 9 parts, Radix Achyranthis Bidentatae 9 parts, Pheretima 9 parts, Herba Asari 3 parts, the Radix Angelicae Dahuricae 9 parts, 9 parts, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of migrainous Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Chuanxiong 25 parts, Radix Puerariae 10 parts, Rhizoma Corydalis 9 parts, Radix Achyranthis Bidentatae 9 parts, Pheretima 9 parts, Herba Asari 3 parts, the Radix Angelicae Dahuricae 9 parts, 9 parts, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of migrainous Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Chuanxiong 25 parts, Radix Puerariae 10 parts, Rhizoma Corydalis 9 parts, Radix Achyranthis Bidentatae 9 parts, Pheretima 9 parts, Herba Asari 3 parts, the Radix Angelicae Dahuricae 9 parts, 9 parts, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510151117.4A CN104721591A (en) | 2015-04-01 | 2015-04-01 | Traditional Chinese medicine for treating migraine |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510151117.4A CN104721591A (en) | 2015-04-01 | 2015-04-01 | Traditional Chinese medicine for treating migraine |
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| CN104721591A true CN104721591A (en) | 2015-06-24 |
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| CN201510151117.4A Withdrawn CN104721591A (en) | 2015-04-01 | 2015-04-01 | Traditional Chinese medicine for treating migraine |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194191A (en) * | 2015-11-06 | 2015-12-30 | 青岛麦瑞特医药技术有限公司 | Traditional Chinese medicine composition for treating tension headache |
| CN105343704A (en) * | 2015-11-18 | 2016-02-24 | 吴斌 | Drug for treating migraine |
| CN105381084A (en) * | 2015-12-23 | 2016-03-09 | 刘可 | Traditional Chinese medicine composition for treating migraine and preparation method and application thereof |
-
2015
- 2015-04-01 CN CN201510151117.4A patent/CN104721591A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194191A (en) * | 2015-11-06 | 2015-12-30 | 青岛麦瑞特医药技术有限公司 | Traditional Chinese medicine composition for treating tension headache |
| CN105343704A (en) * | 2015-11-18 | 2016-02-24 | 吴斌 | Drug for treating migraine |
| CN105381084A (en) * | 2015-12-23 | 2016-03-09 | 刘可 | Traditional Chinese medicine composition for treating migraine and preparation method and application thereof |
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Application publication date: 20150624 |