CH627160A5 - Process for preparing halogenated azetidinone or thiazolinoazetidinone derivatives - Google Patents

Process for preparing halogenated azetidinone or thiazolinoazetidinone derivatives Download PDF

Info

Publication number: CH627160A5
Authority: CH; Switzerland
Prior art keywords: acetate; mixture; oxo; nitrobenzyl; solution
Prior art date: 1975-02-17

Application number

CH191876A

Other languages

German (de)

English (en)

Inventor

Teruji Tsuji

Yoshio Hamashima

Mitsuru Yoshioka

Masayuki Narisada

Hiroshi Tanida

Taichiro Komeno

Wataru Nagata

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-02-17

Filing date

1976-02-17

Publication date

1981-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27457226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH627160(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1975-02-17 Priority claimed from JP50019612A external-priority patent/JPS5198265A/ja

1975-02-21 Priority claimed from JP50022229A external-priority patent/JPS51105051A/ja

1975-03-07 Priority claimed from JP50028452A external-priority patent/JPS609516B2/ja

1975-03-20 Priority claimed from JP50033808A external-priority patent/JPS5817460B2/ja

1976-02-17 Application filed by Shionogi & Co filed Critical Shionogi & Co

1981-12-31 Publication of CH627160A5 publication Critical patent/CH627160A5/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CH191876A 1975-02-17 1976-02-17 Process for preparing halogenated azetidinone or thiazolinoazetidinone derivatives CH627160A5 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP50019612A JPS5198265A (fr)	1975-02-17	1975-02-17
JP50022229A JPS51105051A (fr)	1975-02-21	1975-02-21
JP50028452A JPS609516B2 (ja)	1975-03-07	1975-03-07	セフエム骨格の環化製法
JP50033808A JPS5817460B2 (ja)	1975-03-20	1975-03-20	チアゾリンカンノカイカンホウホウ

Publications (1)

Publication Number	Publication Date
CH627160A5 true CH627160A5 (en)	1981-12-31

Family

ID=27457226

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
CH191876A CH627160A5 (en)	1975-02-17	1976-02-17	Process for preparing halogenated azetidinone or thiazolinoazetidinone derivatives
CH74980A CH634579A5 (en)	1975-02-17	1980-01-30	Process for preparing cephem compounds
CH75080A CH628030A5 (en)	1975-02-17	1980-01-30	Process for the preparation of an enamine compound
CH75180A CH628031A5 (en)	1975-02-17	1980-01-30	Process for the preparation of azetidinone compounds
CH74880A CH630074A5 (en)	1975-02-17	1980-01-30	Process for preparing an acetidinone compound

Family Applications After (4)

Application Number	Title	Priority Date	Filing Date
CH74980A CH634579A5 (en)	1975-02-17	1980-01-30	Process for preparing cephem compounds
CH75080A CH628030A5 (en)	1975-02-17	1980-01-30	Process for the preparation of an enamine compound
CH75180A CH628031A5 (en)	1975-02-17	1980-01-30	Process for the preparation of azetidinone compounds
CH74880A CH630074A5 (en)	1975-02-17	1980-01-30	Process for preparing an acetidinone compound

Country Status (24)

Country	Link
US (4)	US4079181A (fr)
AR (1)	AR225878A1 (fr)
AU (1)	AU508160B2 (fr)
BE (1)	BE838656A (fr)
BG (5)	BG25076A3 (fr)
CA (5)	CA1136132A (fr)
CH (5)	CH627160A5 (fr)
DD (5)	DD127900A5 (fr)
DE (1)	DE2606278A1 (fr)
DK (1)	DK156575C (fr)
ES (1)	ES445250A1 (fr)
FR (1)	FR2334669A1 (fr)
GB (3)	GB1548643A (fr)
GR (1)	GR60437B (fr)
IE (1)	IE42479B1 (fr)
IL (5)	IL49048A (fr)
MX (1)	MX3818E (fr)
NL (1)	NL190721C (fr)
NZ (1)	NZ180037A (fr)
PH (1)	PH18022A (fr)
PT (1)	PT64806B (fr)
RO (4)	RO75006A (fr)
SE (4)	SE421691B (fr)
YU (5)	YU40272B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1136132A (fr) *	1975-02-17	1982-11-23	Teruji Tsuji	Cyclisation pour fermer des noyaux cephem et intermediaires ainsi obtenus
US4550162A (en) *	1975-02-20	1985-10-29	Ciba-Geigy Corporation	Process for the manufacture of enol derivatives
US4579684A (en) *	1975-02-20	1986-04-01	Ciba-Geigy Corporation	Process for the manufacture of enol derivatives
AT342197B (de) *	1975-02-20	1978-03-28	Ciba Geigy Ag	Neues verfahren zur herstellung von 3-cephemverbindungen
GB1543048A (en) *	1976-02-04	1979-03-28	Beecham Group Ltd	4-mercapto-3-phenoxyacetamido-2-azetidinone
US4271305A (en) *	1979-02-01	1981-06-02	Eli Lilly And Company	Thiazolinoazetidinones and process therefor
JPS55133355A (en) *	1979-04-03	1980-10-17	Shionogi & Co Ltd	Inversion of 3-amino group of beta-lactam ring
CA1145339A (fr) *	1979-04-30	1983-04-26	Eli Lilly And Company	Methode de chloration allylique, et composes ainsi obtenus
US4518531A (en) *	1979-04-30	1985-05-21	Eli Lilly And Company	Allylic chlorination process and compounds prepared thereby
CA1148938A (fr) *	1979-05-08	1983-06-28	John R. Corfield	Preparation de cephalosporines et produits intermediaires utilises a cette fin
US4237279A (en) *	1979-07-27	1980-12-02	Eli Lilly And Company	Crystalline 3-hydroxycephalosporin solvates
DE3265390D1 (en) *	1981-05-19	1985-09-19	Ciba Geigy Ag	Process for the preparation of 4-thio-azetidinone compounds
FR2511376A1 (fr) *	1981-08-17	1983-02-18	Rhone Poulenc Sante	Nouveaux derives de la cephalosporine et leur prepration
JPS5832884A (ja) *	1981-08-20	1983-02-25	Otsuka Chem Co Ltd	３−エキソメチレンセフアム誘導体の製造方法
JPS59101485A (ja) *	1982-11-29	1984-06-12	Otsuka Chem Co Ltd	アセチジノン誘導体
US4533497A (en) *	1982-12-27	1985-08-06	Eli Lilly And Company	N-ethylidene azetidinones
KR850000291B1 (ko) *	1983-02-07	1985-03-16	한국과학기술원	3-메틸렌 세팜 화합물의 제조방법
JPS59164771A (ja) *	1983-03-10	1984-09-17	Otsuka Chem Co Ltd	塩素化アゼチジノン誘導体の製造方法
EP0133670A3 (fr) *	1983-08-09	1985-12-18	Bayer Ag	Procédé pour la préparation d'acides 7-acylamino-3-hydroxy-céphème-4-carboxylique et d'acides 7-acylamino-3-hydroxy-1-déthia-1-oxacéphème-4-carboxylique
DE3725375A1 (de) *	1987-07-31	1989-02-09	Bayer Ag	Stabile oxapenem-3-carbonsaeuren
JP3007986B2 (ja) *	1990-03-02	2000-02-14	大塚化学株式会社	β―ラクタム誘導体の製法
DE69126342T2 (de) *	1990-03-08	1997-10-23	Otsuka Kagaku Kk	Thiazolinoazetidinon-Derivat und Verfahren zur Herstellung eines 2-exo-Methylen-penam Derivates daraus
US5604222A (en) *	1993-12-27	1997-02-18	Lupin Laboratories, Ltd.	Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) *	1994-07-11	1996-11-26	Lupin Laboratories Limited	Process for preparation of 3-exomethylene cepham sulfoxide esters
IT1277048B1 (it) *	1995-12-06	1997-11-04	3 Exo S R L	Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con
US5986091A (en) *	1996-03-13	1999-11-16	Otsuka Kagaku Kabushiki Kaisha	Process for preparation of β-lactam compounds
WO2009049086A1 (fr) *	2007-10-09	2009-04-16	Larry Sutton	Inhibiteurs de bêta-lactamase à large spectre
CN101525341B (zh) *	2009-04-01	2012-07-04	浙江东邦药业有限公司	一种3-羟基头孢化合物的制备方法
DK2968352T3 (da)	2013-03-12	2019-01-02	Gladius Pharmaceuticals Corp	Derivatiserede 3-styryl-cephalosporiner
CN108727409A (zh) *	2017-04-24	2018-11-02	浙江省化工研究院有限公司	一种3-羟基头孢菌素的制备方法
CN111647638A (zh) *	2020-04-17	2020-09-11	江苏正泰药业有限公司	一种7-anca的制备工艺
CN115397807B (zh) *	2020-04-17	2024-08-13	帝斯曼知识产权资产管理有限公司	用于制备取代的烯胺化合物的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3862164A (en) *	1971-02-03	1975-01-21	Lilly Co Eli	Thiazolidine azetidinones
GB1457421A (en) *	1973-01-04	1976-12-01	Glaxo Lab Ltd	Cepham derivatives
AU498131B2 (en) *	1974-02-26	1979-02-15	Ciba-Geigy Ag	Production of cephems by cyclization
JPS5188955A (fr) *	1975-01-30	1976-08-04
CA1136132A (fr) *	1975-02-17	1982-11-23	Teruji Tsuji	Cyclisation pour fermer des noyaux cephem et intermediaires ainsi obtenus
AT342197B (de) *	1975-02-20	1978-03-28	Ciba Geigy Ag	Neues verfahren zur herstellung von 3-cephemverbindungen
US4147864A (en) *	1975-02-20	1979-04-03	Ciba-Geigy Corporation	Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
JPS5214789A (en) *	1975-07-22	1977-02-03	Shionogi & Co Ltd	Process for preparing 3-substiuted cephem compounds by ring closure
US4008230A (en) *	1975-10-29	1977-02-15	Eli Lilly And Company	Process for preparing 3-hydroxy cephalosporins
JPS6019315B2 (ja) *	1976-01-23	1985-05-15	塩野義製薬株式会社	アゼチジノン化合物
GB1529913A (en) *	1976-02-04	1978-10-25	Beecham Group Ltd	Beta-lactam compounds
US4264597A (en) *	1978-06-06	1981-04-28	Masashi Hashimoto	Cephalosporin analogues and processes for the preparation thereof

1976
- 1976-02-09 CA CA000245317A patent/CA1136132A/fr not_active Expired
- 1976-02-16 DK DK061976A patent/DK156575C/da active
- 1976-02-16 PT PT64806A patent/PT64806B/pt unknown
- 1976-02-16 IL IL49048A patent/IL49048A/xx unknown
- 1976-02-16 SE SE7601715A patent/SE421691B/xx not_active IP Right Cessation
- 1976-02-17 ES ES445250A patent/ES445250A1/es not_active Expired
- 1976-02-17 NZ NZ180037A patent/NZ180037A/xx unknown
- 1976-02-17 MX MX76898U patent/MX3818E/es unknown
- 1976-02-17 BG BG034108A patent/BG25076A3/xx unknown
- 1976-02-17 US US05/658,665 patent/US4079181A/en not_active Expired - Lifetime
- 1976-02-17 GB GB41074/78A patent/GB1548643A/en not_active Expired
- 1976-02-17 IE IE313/76A patent/IE42479B1/en unknown
- 1976-02-17 FR FR7604318A patent/FR2334669A1/fr active Granted
- 1976-02-17 DD DD7600195995A patent/DD127900A5/xx unknown
- 1976-02-17 DD DD7600195993A patent/DD127899A5/xx unknown
- 1976-02-17 DD DD191283A patent/DD124986A5/xx unknown
- 1976-02-17 DD DD7600195998A patent/DD127902A5/xx unknown
- 1976-02-17 GR GR50078A patent/GR60437B/el unknown
- 1976-02-17 GB GB41073/78A patent/GB1548642A/en not_active Expired
- 1976-02-17 YU YU384/76A patent/YU40272B/xx unknown
- 1976-02-17 BE BE164401A patent/BE838656A/fr not_active IP Right Cessation
- 1976-02-17 CH CH191876A patent/CH627160A5/de not_active IP Right Cessation
- 1976-02-17 BG BG034107A patent/BG27557A4/xx unknown
- 1976-02-17 BG BG032385A patent/BG24948A3/xx unknown
- 1976-02-17 RO RO7694586A patent/RO75006A/fr unknown
- 1976-02-17 BG BG034106A patent/BG25216A3/xx unknown
- 1976-02-17 BG BG034105A patent/BG24949A3/xx unknown
- 1976-02-17 GB GB6187/76A patent/GB1548641A/en not_active Expired
- 1976-02-17 DE DE19762606278 patent/DE2606278A1/de active Granted
- 1976-02-17 RO RO7684836A patent/RO68460A/fr unknown
- 1976-02-17 RO RO7694587A patent/RO74958A/fr unknown
- 1976-02-17 DD DD7600195997A patent/DD127901A5/xx unknown
- 1976-02-17 AU AU11181/76A patent/AU508160B2/en not_active Expired
- 1976-02-17 NL NL7601613A patent/NL190721C/xx not_active IP Right Cessation
- 1976-02-17 AR AR262283A patent/AR225878A1/es active
- 1976-03-03 PH PH18164A patent/PH18022A/en unknown
- 1976-07-17 RO RO197694535A patent/RO74936A/fr unknown
1977
- 1977-12-01 US US05/856,806 patent/US4160085A/en not_active Expired - Lifetime
1978
- 1978-11-26 IL IL56050A patent/IL56050A0/xx not_active IP Right Cessation
- 1978-11-26 IL IL56049A patent/IL56049A0/xx not_active IP Right Cessation
1979
- 1979-05-28 IL IL57418A patent/IL57418A0/xx not_active IP Right Cessation
- 1979-06-11 IL IL57541A patent/IL57541A0/xx unknown
- 1979-09-20 SE SE7907811A patent/SE444811B/sv not_active IP Right Cessation
- 1979-09-20 SE SE7907813A patent/SE434637B/sv not_active IP Right Cessation
- 1979-09-20 SE SE7907812A patent/SE434950B/sv not_active IP Right Cessation
- 1979-10-19 CA CA000337975A patent/CA1095026A/fr not_active Expired
- 1979-10-19 CA CA000337973A patent/CA1144924A/fr not_active Expired
- 1979-10-19 CA CA000337974A patent/CA1077936A/fr not_active Expired
- 1979-10-22 CA CA000338132A patent/CA1132547A/fr not_active Expired
1980
- 1980-01-30 CH CH74980A patent/CH634579A5/de not_active IP Right Cessation
- 1980-01-30 CH CH75080A patent/CH628030A5/de not_active IP Right Cessation
- 1980-01-30 CH CH75180A patent/CH628031A5/de not_active IP Right Cessation
- 1980-01-30 CH CH74880A patent/CH630074A5/de not_active IP Right Cessation
- 1980-02-27 US US06/125,233 patent/US4346218A/en not_active Expired - Lifetime
1982
- 1982-01-11 US US06/338,651 patent/US4440683A/en not_active Expired - Lifetime
- 1982-08-10 YU YU1739/82A patent/YU40412B/xx unknown
- 1982-08-10 YU YU1738/82A patent/YU40411B/xx unknown
- 1982-08-10 YU YU1741/82A patent/YU40413B/xx unknown
- 1982-08-10 YU YU1742/82A patent/YU40414B/xx unknown

Also Published As

Publication number	Publication date
RO74958A (fr)	1980-10-30
SE7601715L (sv)	1976-08-18
GR60437B (en)	1978-05-26
FR2334669A1 (fr)	1977-07-08
CH628030A5 (en)	1982-02-15
YU40411B (en)	1985-12-31
GB1548641A (en)	1979-07-18
ES445250A1 (es)	1977-06-16
IE42479L (en)	1976-08-17
YU38476A (en)	1983-01-21
DD124986A5 (fr)	1977-03-23
YU40413B (en)	1985-12-31
RO68460A (fr)	1981-08-17
SE434950B (sv)	1984-08-27
IE42479B1 (en)	1980-08-13
DD127901A5 (de)	1977-10-19
DD127899A5 (de)	1977-10-19
CH628031A5 (en)	1982-02-15
BG25076A3 (en)	1978-07-12
SE444811B (sv)	1986-05-12
IL56050A0 (en)	1979-01-31
YU173982A (en)	1983-01-21
CH634579A5 (en)	1983-02-15
PH18022A (en)	1985-03-03
CA1144924A (fr)	1983-04-19
GB1548643A (en)	1979-07-18
CA1077936A (fr)	1980-05-20
BG24948A3 (en)	1978-06-15
BG25216A3 (en)	1978-08-10
YU40272B (en)	1985-12-31
SE434637B (sv)	1984-08-06
YU40414B (en)	1985-12-31
PT64806B (en)	1977-07-07
FR2334669B1 (fr)	1981-12-31
AR225878A1 (es)	1982-05-14
SE7907811L (sv)	1979-09-20
SE7907812L (sv)	1979-09-20
CH630074A5 (en)	1982-05-28
US4346218A (en)	1982-08-24
YU173882A (en)	1983-01-21
AU1118176A (en)	1977-08-25
YU40412B (en)	1985-12-31
CA1132547A (fr)	1982-09-28
NL190721C (nl)	1994-07-18
SE421691B (sv)	1982-01-25
NL190721B (nl)	1994-02-16
DK156575C (da)	1990-02-05
AU508160B2 (en)	1980-03-13
NZ180037A (en)	1979-11-01
DK61976A (da)	1976-08-18
DE2606278A1 (de)	1976-08-26
IL57418A0 (en)	1979-09-30
BG24949A3 (en)	1978-06-15
MX3818E (es)	1981-07-30
CA1136132A (fr)	1982-11-23
DE2606278C2 (fr)	1989-05-03
GB1548642A (en)	1979-07-18
SE7907813L (sv)	1979-09-20
RO75006A (fr)	1980-10-30
YU174282A (en)	1983-01-21
BG27557A4 (en)	1979-11-12
DD127902A5 (de)	1977-10-19
IL57541A0 (en)	1979-10-31
US4079181A (en)	1978-03-14
IL49048A (en)	1981-12-31
US4160085A (en)	1979-07-03
IL56049A0 (en)	1979-01-31
IL49048A0 (en)	1976-04-30
YU174182A (en)	1983-01-21
DK156575B (da)	1989-09-11
CA1095026A (fr)	1981-02-03
US4440683A (en)	1984-04-03
BE838656A (fr)	1976-06-16
NL7601613A (nl)	1976-08-19
DD127900A5 (de)	1977-10-19
RO74936A (fr)	1980-10-30

Publication	Publication Date	Title
CH627160A5 (en)	1981-12-31	Process for preparing halogenated azetidinone or thiazolinoazetidinone derivatives
EP0181831B1 (fr)	1993-08-25	Procédé de préparation d'acyloxyazétidinones optiquement actives
US4500456A (en)	1985-02-19	Preparation of 4-fluoroazetidinones using FClO3
DD154542A5 (de)	1982-03-31	Verfahren zur herstellung von 6 beta-hydroxyalkylpenicillansaeuren
DE69032681T2 (de)	1999-02-25	Cephalosporine und ihre Homologen, Verfahren zu ihrer Herstellung und pharmazeutische Präparate
CH632271A5 (de)	1982-09-30	Verfahren zur herstellung von cephalosporinen.
DE2556071A1 (de)	1976-07-08	Sulfinylhalogenide und verfahren zu ihrer herstellung aus penicillin-sulfoxiden
DE3382761T2 (de)	1995-03-09	Verfahren zur Herstellung von Penem-Verbindungen.
CH636618A5 (en)	1983-06-15	1-Oxadethiacepham compounds, and a process for preparing them
EP0110826B1 (fr)	1987-08-19	Dérivés de 6-hydroxy-alkyle-inférieur-pénème, procédé pour leur préparation, compositions pharmaceutiques les contenant et leur application
DE2912483A1 (de)	1979-10-11	Beta -lactamverbindungen, verfahren zu deren herstellung und arzneimittel
CH636100A5 (de)	1983-05-13	Dihydrotriazinylthiooxacephalosporine.
US4332722A (en)	1982-06-01	Cyclization to form cephem ring and intermediates therefor
CH621336A5 (fr)	1981-01-30
DE69231978T2 (de)	2001-11-15	Cephalosporinverbindungen
EP0023887B1 (fr)	1984-11-07	Dérivés d'azétidinone bicycliques substitués en 3, procédé pour leur préparation et intermédiaires ainsi que leur préparation
DE2555182A1 (de)	1976-06-16	3-(1-hydroxyalkyl- oder -1-hydroxyarylalkyl)cepheme und derivate hiervon
EP0075104A2 (fr)	1983-03-30	Dérivés de céphalosporine, procédé pour leur préparation, compositions pharmaceutiques et intermédiaires
CH628620A5 (en)	1982-03-15	Process for the preparation of sulphinylazetidinone compounds
US4455314A (en)	1984-06-19	Penicillin derivatives
KR810001820B1 (ko)	1981-11-16	세펨 화합물 유도체의 제조 방법
DE2735854A1 (de)	1978-02-16	2-oxoazetidin-derivate
EP0221846A1 (fr)	1987-05-13	Acyloxyazétidinones optiquement actives
CH644611A5 (de)	1984-08-15	Substituierte imidazolidinyl-3-chlor-3-cephem-4-carbonsaeuren, verfahren zu ihrer herstellung und pharmazeutische zubereitungen derselben.
DD250532A5 (de)	1987-10-14	Verfahren zur herstellung von optisch aktiven acyloxyazetidinonen

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