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CA2070057A1 - Process for the production of glycosyltransferases - Google Patents

Process for the production of glycosyltransferases

Info

Publication number
CA2070057A1
CA2070057A1 CA002070057A CA2070057A CA2070057A1 CA 2070057 A1 CA2070057 A1 CA 2070057A1 CA 002070057 A CA002070057 A CA 002070057A CA 2070057 A CA2070057 A CA 2070057A CA 2070057 A1 CA2070057 A1 CA 2070057A1
Authority
CA
Canada
Prior art keywords
leu
sequence
promoter
yeast
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002070057A
Other languages
English (en)
French (fr)
Inventor
Gabriele Watzele
Eric G. Berger
Bernd Meyhack
Manfred Watzele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9208211A external-priority patent/GB2256197B/en
Application filed by Individual filed Critical Individual
Publication of CA2070057A1 publication Critical patent/CA2070057A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002070057A 1991-05-31 1992-05-29 Process for the production of glycosyltransferases Abandoned CA2070057A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP91810414 1991-05-31
EP91810414.2 1991-05-31
EP92810167.4 1992-03-04
EP92810167 1992-03-04
GB9208211A GB2256197B (en) 1991-05-31 1992-04-14 Yeast as host for expression of heterologous glycosyl transferase enzymes
GB9208211.4 1992-04-14

Publications (1)

Publication Number Publication Date
CA2070057A1 true CA2070057A1 (en) 1992-12-01

Family

ID=27234292

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002070057A Abandoned CA2070057A1 (en) 1991-05-31 1992-05-29 Process for the production of glycosyltransferases

Country Status (19)

Country Link
JP (1) JPH05199871A (no)
AT (1) AT401940B (no)
AU (1) AU655470B2 (no)
BE (1) BE1005579A5 (no)
CA (1) CA2070057A1 (no)
DK (1) DK71992A (no)
ES (1) ES2046118B1 (no)
FI (1) FI922515A (no)
GR (1) GR920100250A (no)
HU (1) HU212927B (no)
IE (1) IE69059B1 (no)
IL (1) IL102052A0 (no)
IT (1) IT1255044B (no)
LU (1) LU88123A1 (no)
MX (1) MX9202583A (no)
NO (1) NO922134L (no)
NZ (1) NZ242958A (no)
PT (1) PT100545A (no)
SE (1) SE9201544L (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7819584U1 (de) * 1978-06-30 1978-10-12 Howmedica International, Inc. Zweigniederlassung Kiel, 2301 Schoenkirchen Tubenartiger vorratsbehaelter fuer medizinisches spritzgeraet
WO1993018157A1 (en) * 1992-03-09 1993-09-16 The Regents Of The University Of California Compositions and methods for the identification and synthesis of sialyltransferases
CA2405958C (en) * 2000-04-13 2011-08-09 Biotica Technology Limited Hybrid glycosylated products and their production and use
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
CA2522345A1 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
CA2585758C (en) 2004-10-29 2017-08-01 Neose Technologies, Inc. Remodeling and glycopegylation of fibroblast growth factor (fgf)
CA2593682C (en) 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
EP2386571B1 (en) 2005-04-08 2016-06-01 ratiopharm GmbH Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
WO2008011633A2 (en) 2006-07-21 2008-01-24 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
PT2144923E (pt) 2007-04-03 2013-05-15 Biogenerix Ag Métodos de tratamento com g-csf glicopeguilado
EP2170919B8 (en) 2007-06-12 2016-01-20 ratiopharm GmbH Improved process for the production of nucleotide sugars
CN103497246B (zh) 2008-02-27 2016-08-10 诺沃—诺迪斯克有限公司 缀合的因子viii分子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY103358A (en) * 1987-04-15 1993-06-30 Novartis Ag Process for the production of protiens.
WO1990007000A2 (en) * 1988-12-13 1990-06-28 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
EP0515536B1 (en) * 1990-02-14 2000-01-19 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
EP0485532A1 (en) * 1990-04-27 1992-05-20 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen

Also Published As

Publication number Publication date
AU655470B2 (en) 1994-12-22
DK71992D0 (da) 1992-05-29
LU88123A1 (de) 1993-12-06
IL102052A0 (en) 1992-12-30
HUT65728A (en) 1994-07-28
DK71992A (da) 1992-12-01
NO922134D0 (no) 1992-05-29
PT100545A (pt) 1993-08-31
FI922515A (fi) 1992-12-01
NZ242958A (en) 1993-06-25
ITRM920411A0 (it) 1992-05-29
NO922134L (no) 1992-12-01
MX9202583A (es) 1992-11-01
ITRM920411A1 (it) 1993-11-29
ES2046118A1 (es) 1994-01-16
FI922515A0 (fi) 1992-05-29
ES2046118B1 (es) 1994-08-16
GR920100250A (el) 1993-03-31
BE1005579A5 (fr) 1993-11-09
ATA112792A (de) 1996-05-15
IE921769A1 (en) 1992-12-02
IE69059B1 (en) 1996-08-07
SE9201544L (sv) 1992-12-01
HU212927B (en) 1996-12-30
IT1255044B (it) 1995-10-17
SE9201544D0 (sv) 1992-05-15
AT401940B (de) 1996-12-27
JPH05199871A (ja) 1993-08-10
HU9201787D0 (en) 1992-08-28
AU1705292A (en) 1992-12-03

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Legal Events

Date Code Title Description
FZDE Discontinued