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BR112021015887A8 - Método para criopreservação de célula-tronco, população de células-tronco, composição de criopreservação, uso de nac, e kit de criopreservação - Google Patents

Método para criopreservação de célula-tronco, população de células-tronco, composição de criopreservação, uso de nac, e kit de criopreservação

Info

Publication number
BR112021015887A8
BR112021015887A8 BR112021015887A BR112021015887A BR112021015887A8 BR 112021015887 A8 BR112021015887 A8 BR 112021015887A8 BR 112021015887 A BR112021015887 A BR 112021015887A BR 112021015887 A BR112021015887 A BR 112021015887A BR 112021015887 A8 BR112021015887 A8 BR 112021015887A8
Authority
BR
Brazil
Prior art keywords
cryopreservation
stem cell
nac
kit
composition
Prior art date
Application number
BR112021015887A
Other languages
English (en)
Other versions
BR112021015887A2 (pt
Inventor
Lombardo De La Camara Eleuterio
ORTIZ VIRUMBRALES Maitane
Original Assignee
Tigenix S A U
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tigenix S A U, Takeda Pharmaceuticals Co filed Critical Tigenix S A U
Publication of BR112021015887A2 publication Critical patent/BR112021015887A2/pt
Publication of BR112021015887A8 publication Critical patent/BR112021015887A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/44—Thiols, e.g. mercaptoethanol

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

MÉTODO PARA CRIOPRESERVAÇÃO DE CÉLULA-TRONCO, POPULAÇÃO DE CÉLULAS-TRONCO, COMPOSIÇÃO DE CRIOPRESERVAÇÃO, USO DE NAC, E KIT DE CRIOPRESERVAÇÃO. A invenção se refere a métodos para a criopreservação de uma população de células-tronco, incluindo células-tronco mesenquimais (MSCs), como células-tronco estromais derivadas de adipose (ASCs). Mais particularmente, a invenção se refere ao uso de N-acetilcisteína (NAC) em métodos de criopreservação, populações de células obtidas dos ditos métodos, composições compreendendo as ditas células e usos das mesmas.
BR112021015887A 2019-02-13 2020-02-11 Método para criopreservação de célula-tronco, população de células-tronco, composição de criopreservação, uso de nac, e kit de criopreservação BR112021015887A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382099 2019-02-13
EP19382099.0 2019-02-13
PCT/EP2020/053440 WO2020165152A1 (en) 2019-02-13 2020-02-11 Cryopreservation of stem cells

Publications (2)

Publication Number Publication Date
BR112021015887A2 BR112021015887A2 (pt) 2021-10-05
BR112021015887A8 true BR112021015887A8 (pt) 2023-04-11

Family

ID=65529623

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021015887A BR112021015887A8 (pt) 2019-02-13 2020-02-11 Método para criopreservação de célula-tronco, população de células-tronco, composição de criopreservação, uso de nac, e kit de criopreservação

Country Status (9)

Country Link
US (1) US20220104481A1 (pt)
EP (1) EP3923718A1 (pt)
JP (2) JP7548917B2 (pt)
CN (1) CN113423268B (pt)
AU (1) AU2020221966A1 (pt)
BR (1) BR112021015887A8 (pt)
CA (1) CA3129450A1 (pt)
IL (1) IL285580A (pt)
WO (1) WO2020165152A1 (pt)

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WO2020113090A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
US11767511B2 (en) 2018-11-30 2023-09-26 Cellphire, Inc. Platelets as delivery agents
KR20220016092A (ko) 2019-05-03 2022-02-08 셀파이어, 인크. 혈액 생성물을 생산하기 위한 물질 및 방법
CN114450066A (zh) 2019-08-16 2022-05-06 塞尔菲乐有限公司 作为抗血小板剂逆转剂的血栓小体
US20210308185A1 (en) 2020-02-04 2021-10-07 Cellphire, Inc. Methods of treating acquired hemophilia with anti-fibrinolytic loaded platelets
WO2022103861A1 (en) * 2020-11-10 2022-05-19 Cellphire, Inc. Freeze-dried peripheral blood mononuclear cell compositions and methods
JP7280623B2 (ja) * 2020-12-28 2023-05-24 株式会社アビー 細胞凍結保存液、及び細胞凍結方法
CN112798569B (zh) * 2021-02-04 2022-03-01 斡得霈克(武汉)医疗科技有限责任公司 一种原子吸收荧光光谱法测定血液中微量元素的方法
CN113519506B (zh) * 2021-09-07 2021-12-31 依科赛生物科技（太仓）有限公司 一种无蛋白、无dmso细胞冻存液、应用及其制备方法
CN114467913B (zh) * 2021-11-22 2022-11-11 武汉赛尔朗灵科技有限公司 动物肿瘤组织、临床肿瘤组织及活检肿瘤组织样本的长期冻存及复苏方法
JP7318983B2 (ja) * 2021-12-21 2023-08-01 株式会社アビー 細胞凍結保存液、及び細胞凍結方法
CN117717066B (zh) * 2024-02-04 2024-04-26 广东海洋大学 一种胚胎保存液及其冷冻保存方法和在东风螺胚胎冷冻保存中的应用
CN118370312B (zh) * 2024-06-24 2024-10-11 吉林农业大学 一种提高牛囊胚冷冻耐受性的方法

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RU2005122030A (ru) * 2002-12-13 2005-12-20 Селогос (Fr) Композиция культуральной среды, способ культивирования миобласты, полученные таким способом, и их применение
KR100679642B1 (ko) * 2005-11-16 2007-02-06 주식회사 알앤엘바이오 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제
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JP5867912B2 (ja) * 2011-05-11 2016-02-24 国立大学法人福井大学 細胞の凍結保存液および凍結保存方法
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CN107988148A (zh) * 2018-01-24 2018-05-04 北京臻溪谷医学研究中心（有限合伙） 一种子宫内膜干细胞的分离培养方法
CN107974430A (zh) * 2018-01-24 2018-05-01 北京臻溪谷医学研究中心（有限合伙） 一种人脂肪干细胞的获取分离培养方法和干细胞库的构建方法

Also Published As

Publication number Publication date
JP2022520420A (ja) 2022-03-30
US20220104481A1 (en) 2022-04-07
JP2024102232A (ja) 2024-07-30
JP7548917B2 (ja) 2024-09-10
IL285580A (en) 2021-09-30
AU2020221966A1 (en) 2021-09-30
WO2020165152A1 (en) 2020-08-20
CN113423268A (zh) 2021-09-21
EP3923718A1 (en) 2021-12-22
CN113423268B (zh) 2024-04-02
CA3129450A1 (en) 2020-08-20
BR112021015887A2 (pt) 2021-10-05

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP)

B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]