BR112018003227A2 - uso de clorito para tratar doenças dos glóbulos vermelhos e indicações mediadas desta forma - Google Patents
uso de clorito para tratar doenças dos glóbulos vermelhos e indicações mediadas desta formaInfo
- Publication number
- BR112018003227A2 BR112018003227A2 BR112018003227A BR112018003227A BR112018003227A2 BR 112018003227 A2 BR112018003227 A2 BR 112018003227A2 BR 112018003227 A BR112018003227 A BR 112018003227A BR 112018003227 A BR112018003227 A BR 112018003227A BR 112018003227 A2 BR112018003227 A2 BR 112018003227A2
- Authority
- BR
- Brazil
- Prior art keywords
- red blood
- blood cell
- disease
- chlorite
- way
- Prior art date
Links
- 208000030118 Red blood cell disease Diseases 0.000 title abstract 2
- 208000019501 erythrocyte disease Diseases 0.000 title abstract 2
- 229910001919 chlorite Inorganic materials 0.000 title 1
- 229910052619 chlorite group Inorganic materials 0.000 title 1
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 208000007475 hemolytic anemia Diseases 0.000 abstract 2
- 208000032843 Hemorrhage Diseases 0.000 abstract 1
- 208000016988 Hemorrhagic Stroke Diseases 0.000 abstract 1
- 208000018262 Peripheral vascular disease Diseases 0.000 abstract 1
- 230000000740 bleeding effect Effects 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000036252 glycation Effects 0.000 abstract 1
- 208000031169 hemorrhagic disease Diseases 0.000 abstract 1
- 230000002008 hemorrhagic effect Effects 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 208000020658 intracerebral hemorrhage Diseases 0.000 abstract 1
- 208000007056 sickle cell anemia Diseases 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
- 208000019553 vascular disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
método de tratamento de hiperglicemia induzida por doença/disfunção dos glóbulos vermelhos (rbcd) causada pela geração de produtos finais de glicação inicial e tardia. método de tratamento da anemia hemolítica, anemia hemolítica indolente, anemia falciforme, doenças hemorrágicas, derrame cerebral hemorrágico, sangramento hemorrágico. método de tratamento de rbcd para prevenir a progressão para complicações vasculares associadas à diabetes, denominadas como síndrome x, particularmente para prevenir a progressão para doença renal crônica, doença vascular coronariana e doença vascular periférica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562207774P | 2015-08-20 | 2015-08-20 | |
PCT/IB2016/055011 WO2017029648A1 (en) | 2015-08-20 | 2016-08-22 | Use of chlorite to treat red blood cell diseases and indications mediated thereby |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018003227A2 true BR112018003227A2 (pt) | 2018-09-25 |
Family
ID=56896735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018003227A BR112018003227A2 (pt) | 2015-08-20 | 2016-08-22 | uso de clorito para tratar doenças dos glóbulos vermelhos e indicações mediadas desta forma |
Country Status (8)
Country | Link |
---|---|
US (1) | US11813234B2 (pt) |
EP (1) | EP3337489B1 (pt) |
JP (2) | JP6900596B2 (pt) |
CN (1) | CN108135930A (pt) |
BR (1) | BR112018003227A2 (pt) |
CA (1) | CA2995659A1 (pt) |
RU (1) | RU2018109574A (pt) |
WO (1) | WO2017029648A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112168841A (zh) * | 2019-07-05 | 2021-01-05 | 卢序 | 一种增加人一氧化氮生物利用度的方法 |
CN112386606A (zh) * | 2019-08-19 | 2021-02-23 | 卢序 | 一种有第二信使作用增加积极氧化压力的氧化剂的用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4369615B2 (ja) * | 1997-10-06 | 2009-11-25 | ディメサイド アーゲー | 抗原特異的免疫応答を抑制するための化学的に安定化された亜塩素酸塩溶液の使用 |
CA2393136A1 (en) | 1999-11-30 | 2001-06-07 | Oxo Chemie Ag | Evaluating and predicting clinical outcomes by gene expression analysis |
EP1558237A4 (en) * | 2002-09-27 | 2007-01-17 | Martek Biosciences Corp | IMPROVED GLYCEMIC REGULATION IN PREDIABETE AND / OR DIABETES TYPE II USING DOCOSAHEXAENOIC ACID |
WO2008047703A1 (en) * | 2006-10-16 | 2008-04-24 | Sekisui Chemical Co., Ltd. | Hemoglobin determination method |
EP2164502A1 (en) * | 2007-06-01 | 2010-03-24 | Dimethaid AG | Use of wf10 for treating allergic asthma, allergic rhinitis and atopic dermatitis |
US20140287064A1 (en) * | 2009-04-28 | 2014-09-25 | Karen G. Swenholt | Compositions for improving the appearance and/or treating fungal infections of nails, mucus membranes and the integument |
CA2770023A1 (en) * | 2009-08-06 | 2011-02-10 | Neuraltus Pharmaceuticals, Inc. | Treatment of macrophage-related disorders |
US20110118180A1 (en) * | 2009-11-13 | 2011-05-19 | Sanofi-Aventis Deutschland Gmbh | Method of treatment of diabetes type 2 comprising add-on therapy to metformin |
WO2013093891A1 (en) * | 2011-12-22 | 2013-06-27 | Nuvo Research Gmbh | Liposomal chlorite or chlorate compositions |
EP2804612A4 (en) * | 2012-01-19 | 2015-09-02 | Ibt Pharma Inc | THERAPEUTIC USES OF TETRACHLORODECAOXYGEN (TCDO) |
US8748744B2 (en) * | 2012-06-28 | 2014-06-10 | Hubbell Incorporated | Electrical box extender assembly |
CN106413721A (zh) * | 2014-05-16 | 2017-02-15 | 纽拉尔图斯制药公司 | 用于治疗巨噬细胞相关病症的方法和组合物 |
-
2016
- 2016-08-22 BR BR112018003227A patent/BR112018003227A2/pt active Search and Examination
- 2016-08-22 RU RU2018109574A patent/RU2018109574A/ru not_active Application Discontinuation
- 2016-08-22 EP EP16763581.2A patent/EP3337489B1/en active Active
- 2016-08-22 CN CN201680061116.3A patent/CN108135930A/zh active Pending
- 2016-08-22 CA CA2995659A patent/CA2995659A1/en active Pending
- 2016-08-22 JP JP2018528106A patent/JP6900596B2/ja active Active
- 2016-08-22 WO PCT/IB2016/055011 patent/WO2017029648A1/en active Application Filing
- 2016-08-22 US US15/753,516 patent/US11813234B2/en active Active
-
2021
- 2021-05-06 JP JP2021078253A patent/JP2021130664A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
RU2018109574A (ru) | 2019-09-23 |
JP6900596B2 (ja) | 2021-07-07 |
WO2017029648A1 (en) | 2017-02-23 |
CA2995659A1 (en) | 2017-02-23 |
JP2018523711A (ja) | 2018-08-23 |
EP3337489B1 (en) | 2023-01-18 |
JP2021130664A (ja) | 2021-09-09 |
US20180243334A1 (en) | 2018-08-30 |
CN108135930A (zh) | 2018-06-08 |
US11813234B2 (en) | 2023-11-14 |
EP3337489A1 (en) | 2018-06-27 |
RU2018109574A3 (pt) | 2020-02-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2017062862A3 (en) | Oligonucleotide compositions and methods thereof | |
BR112018016001A2 (pt) | composição farmacêutica, métodos de tratamento e usos da mesma | |
EP4218816A3 (en) | Pharmaceutical composition for use in prevention and/or treatment of disease that develops or progresses as a result of decrease or loss of activity of blood coagulation factor viii and/or activated blood coagulation factor viii | |
MX2017010734A (es) | Terapia de combinacion con factores de coagulacion y anticuepos multiespecificos. | |
BR112019008384A2 (pt) | composição farmacêutica, processos para tratamento e seus usos | |
BR112018011272A2 (pt) | regimes de dosagem para 2-hidróxi-6-((2-(1-isopropil-1h-pirazol-5-il)piridin-3-il)metóxi)benzaldeído | |
BR112015009948A8 (pt) | Antagonistas de ativina-actrii, usos dos mesmos para tratamento de doenças ósseas e outros distúrbios e método para monitorar a eficácia do tratamento ou prevenção de uma doença óssea e outros distúrbios | |
GT201600084A (es) | (aza) piridopirazolopirimidinonas e indazolopirimidinonas y su uso | |
MX2019002510A (es) | Metodos para usar un anticuerpo biespecifico que reconoce el factor de coagulacion ix y/o el factor de coagulacion ix activado y el factor de coagulacion x y/o factor de coagulacion x activado. | |
EA033286B1 (ru) | Способ лечения или отсрочки развития хронической болезни почек | |
BR112016010454A2 (pt) | métodos para tratar uma taupatia | |
EA201791898A1 (ru) | Новые антитела, связывающиеся с tfpi, и содержащая их композиция | |
BR112017018963A2 (pt) | método para tratar anemia por deficiência de ferro | |
AU2017261919A1 (en) | Fat and medical uses thereof | |
BR112018003227A2 (pt) | uso de clorito para tratar doenças dos glóbulos vermelhos e indicações mediadas desta forma | |
RU2011104958A (ru) | Средство для комплексной терапии заболеваний, включающее дигидрокверцетин | |
WO2015051135A3 (en) | Organic compositions to treat hepcidin-related diseases | |
WO2015027121A3 (en) | Cancer treatment | |
MX2023005014A (es) | Metodos de tratamiento de enfermedades inflamatorias cronicas. | |
MX2018013203A (es) | Ciclodextrinas como procoagulantes. | |
BR112016028402A2 (pt) | toxina botulínica para uso no tratamento da paratonia | |
RU2016141712A (ru) | Способ лечения инфильтратов после склеротерапии варикозного расширения вен | |
MX2018003954A (es) | Metodos para mejorar la actividad de retinoides. | |
BR112015023404A2 (pt) | sequestrantes de precursores de produto final de glicação avançada (age) | |
CY1124597T1 (el) | Εκχυλισμα λαδιου gynura procumbens για τη θεραπεια διαφορων δερματολογικων ασθενειων και η διαδικασια παρασκευης του |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] |