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BR0206062A - Formas de dosagem tendo um núcleo interno e invólucro externo - Google Patents

Formas de dosagem tendo um núcleo interno e invólucro externo

Info

Publication number
BR0206062A
BR0206062A BR0206062-0A BR0206062A BR0206062A BR 0206062 A BR0206062 A BR 0206062A BR 0206062 A BR0206062 A BR 0206062A BR 0206062 A BR0206062 A BR 0206062A
Authority
BR
Brazil
Prior art keywords
dosage form
core
less
shell
substantially free
Prior art date
Application number
BR0206062-0A
Other languages
English (en)
Inventor
Frank J Bunick
Harry S Sowden
Martin Thomas
John Burke
Der-Yang Lee
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/967,414 external-priority patent/US6742646B2/en
Priority claimed from US09/966,450 external-priority patent/US6982094B2/en
Priority claimed from US09/966,509 external-priority patent/US6767200B2/en
Priority claimed from US09/966,497 external-priority patent/US7122143B2/en
Priority claimed from US09/966,939 external-priority patent/US6837696B2/en
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of BR0206062A publication Critical patent/BR0206062A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/02—Apparatus specially adapted for manufacture or treatment of sweetmeats or confectionery; Accessories therefor
    • A23G3/04—Sugar-cookers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/50—Cocoa products, e.g. chocolate; Substitutes therefor characterised by shape, structure or physical form, e.g. products with an inedible support
    • A23G1/54—Composite products, e.g. layered laminated, coated, filled
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/0002—Processes of manufacture not relating to composition and compounding ingredients
    • A23G3/0004—Processes specially adapted for manufacture or treatment of sweetmeats or confectionery
    • A23G3/0019—Shaping of liquid, paste, powder; Manufacture of moulded articles, e.g. modelling, moulding, calendering
    • A23G3/0025—Processes in which the material is shaped at least partially in a mould in the hollows of a surface, a drum, an endless band, or by a drop-by-drop casting or dispensing of the material on a surface, e.g. injection moulding, transfer moulding
    • A23G3/0029—Moulding processes for hollow products, e.g. opened shell
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
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    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Confectionery (AREA)

Abstract

"FORMAS DE DOSAGEM TENDO UM NúCLEO INTERNO E INVóLUCRO EXTERNO". Em uma modalidade, a forma de dosagem da presente invenção compreende um núcleo tendo uma superfície externa e um invólucro tendo superfícies externas e internas, na qual o invólucro envolve o núcleo de tal modo que a superfície interna de invólucro fique substancialmente conformada sobre a superfície externa de núcleo, a espessura de invólucro fique na faixa de cerca de 100 a 400 mícrons, o desvio padrão relativo da espessura de invólucro na forma de dosagem é menor que cerca de 30%, o invólucro compreende menos que cerca de 50% de açúcar cristalizável, e a forma de dosagem é substancialmente isenta de agentes de controle de carga. Em uma outra modalidade, a forma de dosagem compreende um núcleo tendo uma superfície externa e um invólucro tendo superfícies externas e internas, nas quais o invólucro envolve o núcleo, o deslocamento ascendente de umidade da forma de dosagem a 60 minutos de exposição a 40<198>C e 75% de umidade relativa é menor que cerca de 0,80%, a espessura de invólucro fica na faixa de cerca de 100 - 400 mícrons, o desvio padrão relativo da espessura de invólucro na forma de dosagem é menor que cerca de 30%, a forma de dosagem é substancialmente isenta de agentes de controle de carga e o invólucro é substancialmente isento de uma emenda elevada.
BR0206062-0A 2001-09-28 2002-09-28 Formas de dosagem tendo um núcleo interno e invólucro externo BR0206062A (pt)

Applications Claiming Priority (6)

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US09/967,414 US6742646B2 (en) 2001-09-28 2001-09-28 Systems, methods and apparatuses for manufacturing dosage forms
US09/966,450 US6982094B2 (en) 2001-09-28 2001-09-28 Systems, methods and apparatuses for manufacturing dosage forms
US09/966,509 US6767200B2 (en) 2001-09-28 2001-09-28 Systems, methods and apparatuses for manufacturing dosage forms
US09/966,497 US7122143B2 (en) 2001-09-28 2001-09-28 Methods for manufacturing dosage forms
US09/966,939 US6837696B2 (en) 2001-09-28 2001-09-28 Apparatus for manufacturing dosage forms
PCT/US2002/031066 WO2003026612A2 (en) 2001-09-28 2002-09-28 Dosage forms having an inner core and outer shell

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BR0212950-7A BR0212950A (pt) 2001-09-28 2002-09-28 Formas de dosagens compósitas tendo uma porção inserida
BR0213588-4A BR0213588A (pt) 2001-09-28 2002-09-28 Formas de dosagens de liberação modificada
BR0213589-2A BR0213589A (pt) 2001-09-28 2002-09-28 Formas de dosagens de liberação modificada
BR0212921-3A BR0212921A (pt) 2001-09-28 2002-09-28 Composição farmacêutica com base em fondant
BR0213591-4A BR0213591A (pt) 2001-09-28 2002-09-28 Composição comestìvel e forma de dosagem compreendendo uma parte externa comestìvel
BR0212946-9A BR0212946A (pt) 2001-09-28 2002-09-28 Formas de dosagens de liberação modificada
BR0212951-5A BR0212951A (pt) 2001-09-28 2002-09-28 Formas de dosagens compósitas
BR0206061-2A BR0206061A (pt) 2001-09-28 2002-09-28 Formas de dosagem que apresentam um núcleo interno e um invólucro externo com diferentes formas
BR0206086-8A BR0206086A (pt) 2001-09-28 2002-09-28 Formas de dosagem de liberação modificada
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BR0212950-7A BR0212950A (pt) 2001-09-28 2002-09-28 Formas de dosagens compósitas tendo uma porção inserida
BR0213588-4A BR0213588A (pt) 2001-09-28 2002-09-28 Formas de dosagens de liberação modificada
BR0213589-2A BR0213589A (pt) 2001-09-28 2002-09-28 Formas de dosagens de liberação modificada
BR0212921-3A BR0212921A (pt) 2001-09-28 2002-09-28 Composição farmacêutica com base em fondant
BR0213591-4A BR0213591A (pt) 2001-09-28 2002-09-28 Composição comestìvel e forma de dosagem compreendendo uma parte externa comestìvel
BR0212946-9A BR0212946A (pt) 2001-09-28 2002-09-28 Formas de dosagens de liberação modificada
BR0212951-5A BR0212951A (pt) 2001-09-28 2002-09-28 Formas de dosagens compósitas
BR0206061-2A BR0206061A (pt) 2001-09-28 2002-09-28 Formas de dosagem que apresentam um núcleo interno e um invólucro externo com diferentes formas
BR0206086-8A BR0206086A (pt) 2001-09-28 2002-09-28 Formas de dosagem de liberação modificada

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WO2003026624A1 (en) 2003-04-03
JP2005508329A (ja) 2005-03-31
WO2003026616A1 (en) 2003-04-03
WO2003026629A2 (en) 2003-04-03
MXPA04002891A (es) 2005-06-20
NO20032362D0 (no) 2003-05-26
EP1429743A1 (en) 2004-06-23
CN1607945A (zh) 2005-04-20
US20040170750A1 (en) 2004-09-02
US20030232083A1 (en) 2003-12-18
NZ532096A (en) 2006-10-27
NO20032364L (no) 2003-07-25
EP1429724A1 (en) 2004-06-23
HUP0401686A2 (hu) 2004-11-29
CA2461659C (en) 2010-12-07
ATE476957T1 (de) 2010-08-15
BR0213591A (pt) 2004-08-31
NO20032363D0 (no) 2003-05-26
ATE507823T1 (de) 2011-05-15
CA2461616A1 (en) 2003-04-03
WO2003026630A1 (en) 2003-04-03
CN1592610A (zh) 2005-03-09
KR20040066094A (ko) 2004-07-23
DE60223269T2 (de) 2008-08-21
WO2003026613A1 (en) 2003-04-03
JP2005508325A (ja) 2005-03-31
WO2003026625A1 (en) 2003-04-03
NO20032364D0 (no) 2003-05-26
WO2003026612A3 (en) 2003-06-26
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WO2003026626A2 (en) 2003-04-03
US20030232082A1 (en) 2003-12-18
WO2003026627A1 (en) 2003-04-03
WO2003026628A3 (en) 2003-05-01
EP1438018B1 (en) 2010-08-11
CN1596101A (zh) 2005-03-16
MXPA04002884A (es) 2005-06-20
EP1429746A2 (en) 2004-06-23
MXPA04002974A (es) 2005-06-20
DE60237294D1 (de) 2010-09-23
CN1592611A (zh) 2005-03-09
BR0206061A (pt) 2004-01-13
MXPA04002977A (es) 2005-06-20
WO2003026612A2 (en) 2003-04-03
EP1429742A2 (en) 2004-06-23
MXPA04002992A (es) 2005-06-20
US20040062804A1 (en) 2004-04-01
NZ532097A (en) 2006-02-24
US7635490B2 (en) 2009-12-22
WO2003026615A3 (en) 2003-07-31
US20040018327A1 (en) 2004-01-29
WO2003026624A9 (en) 2004-05-06
BR0213588A (pt) 2004-08-31
PT1429738E (pt) 2007-12-14
BR0212946A (pt) 2004-10-26
CA2447984A1 (en) 2003-04-03
US20040213849A1 (en) 2004-10-28
EP1429737A1 (en) 2004-06-23
CN1596100A (zh) 2005-03-16
US7416738B2 (en) 2008-08-26
US8545887B2 (en) 2013-10-01
US20080305150A1 (en) 2008-12-11
BR0212950A (pt) 2004-10-26
CN1638740A (zh) 2005-07-13
NZ532568A (en) 2005-07-29
CA2461684A1 (en) 2003-04-03
KR20040045026A (ko) 2004-05-31
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NO20032362L (no) 2003-07-14
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ATE376826T1 (de) 2007-11-15
ES2311073T3 (es) 2009-02-01
US20040213848A1 (en) 2004-10-28
BR0206086A (pt) 2003-12-23
EP1429738B1 (en) 2007-10-31
JP2005508330A (ja) 2005-03-31
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EP1432404A1 (en) 2004-06-30
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US20050019407A1 (en) 2005-01-27
KR20040037207A (ko) 2004-05-04
DE60239945D1 (de) 2011-06-16
CA2461865A1 (en) 2003-04-03
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US7968120B2 (en) 2011-06-28
US20030219484A1 (en) 2003-11-27
MXPA04002978A (es) 2005-06-20
JP2005509605A (ja) 2005-04-14
JP2005508327A (ja) 2005-03-31
JP2005511515A (ja) 2005-04-28
CN1592612A (zh) 2005-03-09
ES2295427T3 (es) 2008-04-16
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ATE404179T1 (de) 2008-08-15
JP2005535558A (ja) 2005-11-24
EP1463489A1 (en) 2004-10-06
US20050266084A1 (en) 2005-12-01
ES2444549T3 (es) 2014-02-25
KR20040037208A (ko) 2004-05-04
CA2446760A1 (en) 2003-04-03
JP2005508326A (ja) 2005-03-31
KR20040045032A (ko) 2004-05-31
US20030235616A1 (en) 2003-12-25
JP2005509604A (ja) 2005-04-14
WO2003026625A9 (en) 2004-05-06
US20090155372A1 (en) 2009-06-18
KR20040045031A (ko) 2004-05-31
PL369134A1 (en) 2005-04-18
MXPA04002976A (es) 2005-06-20
MXPA04002979A (es) 2005-06-20
KR20040037206A (ko) 2004-05-04
EP1438030A2 (en) 2004-07-21
BR0212921A (pt) 2004-10-13
CA2461354C (en) 2010-04-27
CN1592613A (zh) 2005-03-09
BR0213589A (pt) 2004-08-31
JP2005508328A (ja) 2005-03-31
US20040241236A1 (en) 2004-12-02
CA2446759A1 (en) 2003-04-03
BR0212951A (pt) 2004-10-26
CA2461682A1 (en) 2003-04-03
EP1429745A2 (en) 2004-06-23
BR0213593A (pt) 2004-08-31
KR20040045030A (ko) 2004-05-31
EP1429738A2 (en) 2004-06-23
AU2002330164A1 (en) 2003-04-07
DE60223269D1 (de) 2007-12-13
KR20040045034A (ko) 2004-05-31
CN100364515C (zh) 2008-01-30
CA2461656A1 (en) 2003-04-03
EP1429742B1 (en) 2011-05-04
WO2003026614A9 (en) 2004-02-26
EP1438028A1 (en) 2004-07-21
DE60228281D1 (de) 2008-09-25

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