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BE859012A - Derives de 4-n-acylfortimicines b, leur preparation et leur application - Google Patents

Derives de 4-n-acylfortimicines b, leur preparation et leur application

Info

Publication number
BE859012A
BE859012A BE181169A BE181169A BE859012A BE 859012 A BE859012 A BE 859012A BE 181169 A BE181169 A BE 181169A BE 181169 A BE181169 A BE 181169A BE 859012 A BE859012 A BE 859012A
Authority
BE
Belgium
Prior art keywords
acylfortimicins
derivatives
preparation
application
Prior art date
Application number
BE181169A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BE859012A publication Critical patent/BE859012A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE181169A 1976-09-23 1977-09-23 Derives de 4-n-acylfortimicines b, leur preparation et leur application BE859012A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/725,829 US4091032A (en) 1976-09-23 1976-09-23 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

Publications (1)

Publication Number Publication Date
BE859012A true BE859012A (fr) 1978-03-23

Family

ID=24916124

Family Applications (1)

Application Number Title Priority Date Filing Date
BE181169A BE859012A (fr) 1976-09-23 1977-09-23 Derives de 4-n-acylfortimicines b, leur preparation et leur application

Country Status (17)

Country Link
US (2) US4091032A (fr)
JP (1) JPS5368752A (fr)
AR (1) AR224722A1 (fr)
AU (1) AU519064B2 (fr)
BE (1) BE859012A (fr)
CA (1) CA1114809A (fr)
DE (1) DE2742949C2 (fr)
DK (1) DK419877A (fr)
ES (2) ES462566A1 (fr)
FR (1) FR2365586A1 (fr)
GB (2) GB1591320A (fr)
GR (1) GR63596B (fr)
NO (1) NO773256L (fr)
NZ (1) NZ185239A (fr)
PH (1) PH16052A (fr)
SE (1) SE7710683L (fr)
ZA (2) ZA775651B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR66054B (fr) * 1976-10-28 1981-01-14 Abbott Lab
JPS5466679A (en) * 1977-11-07 1979-05-29 Kyowa Hakko Kogyo Co Ltd Novel antibiotic substance fortimicin kf and fortimicin kg, and their preparation
US4214075A (en) * 1977-12-21 1980-07-22 Abbott Laboratories 6'-Epi-fortimicin A and B derivatives
JPS6041679B2 (ja) * 1978-03-03 1985-09-18 協和醗酵工業株式会社 新抗生物質ホ−テイマイシンkg↓1,kg↓2およびkg↓3ならびにそれらの製造法
US4234717A (en) * 1978-03-30 1980-11-18 American Cyanamid Company Antibacterial antibiotic BM782
US4208407A (en) * 1979-02-05 1980-06-17 Abbott Laboratories 5-Deoxyfortimicin A, 2,5-dideoxyfortimicin A and the corresponding 4-N-acyl and alkyl fortimicin B derivatives thereof and intermediates therefor
US4207415A (en) * 1979-02-05 1980-06-10 Abbott Laboratories Method of producing 2-deoxyfortimicin A
US4214079A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives
US4219643A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AN
US4226979A (en) * 1979-03-29 1980-10-07 Abbott Laboratories Fortimicin AK
US4331804A (en) * 1979-03-29 1982-05-25 Abbott Laboratories 2-Epi-fortimicin A and derivatives
US4213972A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'Di-N-fortimicins AH and AI
US4293689A (en) * 1979-03-29 1981-10-06 Abbott Laboratories Method of producing 3-O-demethylfortimicin B from fortimicin AN
US4213971A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AD derivatives
US4214080A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicins AM and AP
US4219642A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AO
BE882501A (fr) * 1979-03-29 1980-09-29 Abbott Lab 2-epifortimicine a et derives, et leurs applications therapeutiques
US4219644A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicins AH and AI
US4213974A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N,2'-N and 4,2'-Di-N-fortimicin AO derivatives
US4214078A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicin AL
US4218442A (en) * 1979-03-29 1980-08-19 Abbott Laboratories 1-Epi-fortimicin A and derivatives
US4216210A (en) * 1979-03-29 1980-08-05 Abbott Laboratories Fortimicins AM and AP derivatives
US4269970A (en) * 1979-09-26 1981-05-26 Abbott Laboratories 1,2-Carbamates of fortimicin B and derivatives
US4232147A (en) * 1979-09-26 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B-1,5-carbamates
US4275193A (en) * 1979-09-26 1981-06-23 Abbott Laboratories 4,5-Carbamates of fortimicin B
US4230846A (en) * 1979-09-26 1980-10-28 Abbott Laboratories 1,5-Carbamates of fortimicin B and derivatives
US4263429A (en) * 1979-09-26 1981-04-21 Abbott Laboratories 1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate
US4273925A (en) * 1979-09-26 1981-06-16 Abbott Laboratories 1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture
US4431799A (en) * 1979-09-26 1984-02-14 Abbott Laboratories 6'-Modified fortimicin compounds
US4340727A (en) * 1979-09-26 1982-07-20 Abbott Laboratories 1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture
US4252972A (en) * 1979-09-26 1981-02-24 Abbott Laboratories Fortimicin B-1,2:4,5-bis-carbamates
US4382926A (en) * 1980-04-01 1983-05-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Formimidoyl A and B useful as semi-synthetic aminoglycosidic antibiotics
US4338309A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4',5'-Dihydro-antibiotic AX-127B-1; 2'-N-des-β-lysyl-4',5'-dihydro-antibiotic AX-127B-1; and 4-N-derivatives thereof
US4338307A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 2'-N-Des-β-lysyl antibiotic AX-127B-1 and 4-N-acyl and alkyl derivatives thereof
US4338308A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4-N-β-Lysyl-2'-N-des-β-lysyl antibiotic AX-127B-1 and the pharmaceutically acceptable salts thereof
IE54288B1 (en) * 1982-03-05 1989-08-16 Fujisawa Pharmaceutical Co New 1,4-diaminocyclitol derivatives, processes for their preparation and pharmaceutical compositions containing them

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5145675B2 (fr) * 1973-07-23 1976-12-04
JPS5246311B2 (fr) * 1973-04-17 1977-11-24
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
JPS50145588A (fr) * 1974-05-16 1975-11-21

Also Published As

Publication number Publication date
ZA775651B (en) 1979-07-25
US4155902A (en) 1979-05-22
AR224722A1 (es) 1982-01-15
FR2365586A1 (fr) 1978-04-21
ES462566A1 (es) 1978-11-16
DK419877A (da) 1978-03-24
GB1591320A (en) 1981-06-17
ES472608A1 (es) 1979-02-16
DE2742949C2 (de) 1983-08-04
JPS5368752A (en) 1978-06-19
GR63596B (en) 1979-11-26
ZA775652B (en) 1979-04-25
FR2365586B1 (fr) 1982-12-17
AU2902577A (en) 1979-03-29
GB1591606A (en) 1981-06-24
NO773256L (no) 1978-03-29
NZ185239A (en) 1980-08-26
CA1114809A (fr) 1981-12-22
US4091032A (en) 1978-05-23
DE2742949A1 (de) 1978-03-30
PH16052A (en) 1983-06-02
SE7710683L (sv) 1978-03-24
AU519064B2 (en) 1981-11-05

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