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BE639393A - - Google Patents

Info

Publication number
BE639393A
BE639393A BE639393DA BE639393A BE 639393 A BE639393 A BE 639393A BE 639393D A BE639393D A BE 639393DA BE 639393 A BE639393 A BE 639393A
Authority
BE
Belgium
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of BE639393A publication Critical patent/BE639393A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE639393D 1962-10-30 BE639393A (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23421362A 1962-10-30 1962-10-30
US311291A US3300494A (en) 1962-10-30 1963-09-27 Pyrazinamidoguanidine products

Publications (1)

Publication Number Publication Date
BE639393A true BE639393A (ro)

Family

ID=26927676

Family Applications (1)

Application Number Title Priority Date Filing Date
BE639393D BE639393A (ro) 1962-10-30

Country Status (12)

Country Link
US (1) US3300494A (ro)
BE (1) BE639393A (ro)
BR (1) BR6353917D0 (ro)
CH (2) CH454879A (ro)
CY (1) CY535A (ro)
DE (1) DE1470052A1 (ro)
DK (2) DK108310C (ro)
FR (1) FR1552762A (ro)
GB (2) GB1067474A (ro)
MY (1) MY7000080A (ro)
NL (1) NL299929A (ro)
SE (3) SE319179B (ro)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795438B1 (de) * 1962-10-30 1973-09-06 Merck & Co Inc 3,0-Diamino-6-chlor-pyrazincarbonsaeuremethylester und Verfahren zu dessen Herstellung

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6501301A (ro) * 1964-04-03 1965-10-04
US3455919A (en) * 1966-09-01 1969-07-15 Merck & Co Inc 5-dechlorination of 3-amino-5,6-dichloropyrazinoyl compounds
US3507865A (en) * 1967-04-27 1970-04-21 Merck & Co Inc 3-hydroxy- and 3-mercaptopyrazinamidoguanidines the corresponding ethers and thioethers and processes for their preparation
US3539569A (en) * 1968-08-21 1970-11-10 Merck & Co Inc Preparation of pyrazinoylguanidines from pyrazinoylureas
US4085211A (en) * 1975-12-15 1978-04-18 Merck & Co., Inc. Pyrazinecarboxamides and processes for preparing same
US4087526A (en) * 1976-07-23 1978-05-02 Merck & Co., Inc. (3-Amino-5-substituted-6-fluoropyrazinoyl or pyrazamido)-guanidines and their derivatives bearing substituents on the guanidino nitrogens
US4224447A (en) * 1979-03-27 1980-09-23 Merck & Co., Inc. Novel pyrazinecarboxamides and processes for preparing same
US4604394A (en) * 1984-10-01 1986-08-05 Merck & Co., Inc. Antiarrhythmic compositions and method
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
IN172842B (ro) * 1990-05-17 1993-12-11 Boots Pharmaceuticals Limited
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
CN105073717B (zh) 2012-12-17 2018-05-22 帕里昂科学公司 可用于治疗由黏膜水化不足造成的疾病的氯-吡嗪甲酰胺衍生物
AU2013363215B2 (en) 2012-12-17 2018-03-01 Parion Sciences, Inc. 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1672029A (en) * 1924-08-05 1928-06-05 C A F Kahlbaum Chem Fab G M B Process for the production of amidoguanidines and their alkyl derivatives
US2408694A (en) * 1942-05-29 1946-10-01 Libbey Owens Ford Glass Co Method of preparing acyl guanidines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795438B1 (de) * 1962-10-30 1973-09-06 Merck & Co Inc 3,0-Diamino-6-chlor-pyrazincarbonsaeuremethylester und Verfahren zu dessen Herstellung

Also Published As

Publication number Publication date
DE1470052A1 (de) 1969-02-13
NL299929A (ro)
CH471798A (de) 1969-04-30
DK108310C (da) 1967-11-13
BR6353917D0 (pt) 1973-07-12
GB1067473A (en) 1967-05-03
US3300494A (en) 1967-01-24
CY535A (en) 1970-04-10
GB1067474A (en) 1967-05-03
DK108864C (da) 1968-02-19
SE334614B (ro) 1971-05-03
CH454879A (de) 1968-04-30
SE348734B (ro) 1972-09-11
SE319179B (ro) 1970-01-12
FR1552762A (ro) 1969-01-10
MY7000080A (en) 1970-12-31

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