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AU556589B2 - 2,4,6-trimethoxy phenyl-3-hexamethylene-iminopropyl-ketone - Google Patents

2,4,6-trimethoxy phenyl-3-hexamethylene-iminopropyl-ketone

Info

Publication number
AU556589B2
AU556589B2 AU20568/83A AU2056883A AU556589B2 AU 556589 B2 AU556589 B2 AU 556589B2 AU 20568/83 A AU20568/83 A AU 20568/83A AU 2056883 A AU2056883 A AU 2056883A AU 556589 B2 AU556589 B2 AU 556589B2
Authority
AU
Australia
Prior art keywords
ketone
iminopropyl
hexamethylene
trimethoxy phenyl
hexamethyleneiminopropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU20568/83A
Other versions
AU2056883A (en
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Publication of AU2056883A publication Critical patent/AU2056883A/en
Application granted granted Critical
Publication of AU556589B2 publication Critical patent/AU556589B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Claims for the contracting state AT Use of the (2,4,6-trimethoxyphenyl)-3-(hexamethyleneiminopropyl)-ketone having the following structural formula see diagramm : EP0110748,P6,F1 and its non toxic addition salts, for the manufacture of a medicine. 1. Claims for the contracting states BE, CH, DE, FR, GB, IT, LI, LU, NL, SE, The (2,4,6-trimethoxyphenyl)-(3-hexamethyleneiminopropyl)-ketone having the following structural formula see diagramm : EP0110748,P7,F1 and its addition salts.
AU20568/83A 1982-10-26 1983-10-25 2,4,6-trimethoxy phenyl-3-hexamethylene-iminopropyl-ketone Ceased AU556589B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8217937 1982-10-26
FR8217937A FR2534916B1 (en) 1982-10-26 1982-10-26 NOVEL PHENYL- (3-AMINOPROPYL) -CETONE DERIVATIVES, USE IN THERAPEUTICS AND PREPARATION METHOD

Publications (2)

Publication Number Publication Date
AU2056883A AU2056883A (en) 1984-05-03
AU556589B2 true AU556589B2 (en) 1986-11-13

Family

ID=9278617

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20568/83A Ceased AU556589B2 (en) 1982-10-26 1983-10-25 2,4,6-trimethoxy phenyl-3-hexamethylene-iminopropyl-ketone

Country Status (11)

Country Link
EP (1) EP0110748B1 (en)
JP (1) JPS5995283A (en)
AT (1) ATE26712T1 (en)
AU (1) AU556589B2 (en)
CA (1) CA1212944A (en)
DE (1) DE3371077D1 (en)
DK (1) DK156003C (en)
ES (1) ES8406069A1 (en)
FR (1) FR2534916B1 (en)
GR (1) GR79617B (en)
IE (1) IE56129B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584715B1 (en) * 1985-07-10 1987-10-09 Lafon Labor PHENYL- (3-HEXAMETHYLENEIMINOPROPYL) -CETONE, PROCESS FOR PREPARATION AND THERAPEUTIC USE
CN1058262C (en) * 1993-05-26 2000-11-08 森德克斯(美国)股份有限公司 Novel 1-phenylalkanone 5-HT4 receptor ligands

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6945M (en) * 1967-12-22 1969-05-12
FR2092133B1 (en) * 1970-05-06 1974-03-22 Orsymonde
FR2101045A1 (en) * 1970-08-12 1972-03-31 Penciolelli Madeleine Omega-dialkylamino-1-(2,4,6-trialkoxy phenyl) alkan-1-ones - with vasodilator and spasmolytic activity
FR2134218A1 (en) * 1971-04-27 1972-12-08 Penciolelli Madeleine Phloroglucinol aminoketones - vasodilators and antispasmodics

Also Published As

Publication number Publication date
ES526736A0 (en) 1984-07-01
AU2056883A (en) 1984-05-03
ES8406069A1 (en) 1984-07-01
DK156003B (en) 1989-06-12
DK489283D0 (en) 1983-10-25
DK156003C (en) 1989-11-13
EP0110748A1 (en) 1984-06-13
JPS5995283A (en) 1984-06-01
IE56129B1 (en) 1991-04-24
GR79617B (en) 1984-10-31
FR2534916A1 (en) 1984-04-27
FR2534916B1 (en) 1985-11-22
CA1212944A (en) 1986-10-21
ATE26712T1 (en) 1987-05-15
EP0110748B1 (en) 1987-04-22
DK489283A (en) 1984-04-27
DE3371077D1 (en) 1987-05-27
IE832488L (en) 1984-04-26

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