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AU2892997A - Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits - Google Patents

Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits

Info

Publication number
AU2892997A
AU2892997A AU28929/97A AU2892997A AU2892997A AU 2892997 A AU2892997 A AU 2892997A AU 28929/97 A AU28929/97 A AU 28929/97A AU 2892997 A AU2892997 A AU 2892997A AU 2892997 A AU2892997 A AU 2892997A
Authority
AU
Australia
Prior art keywords
pluripotent
generation
cell lines
embryonic stem
rabbit embryonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU28929/97A
Inventor
Randall Moreadith
Luc Schoonjans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Original Assignee
Katholieke Universiteit Leuven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven
Publication of AU2892997A publication Critical patent/AU2892997A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8777—Rabbit embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU28929/97A 1996-04-29 1997-04-29 Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits Abandoned AU2892997A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP96201169 1996-04-29
EP96201169 1996-04-29
EP96203060 1996-11-04
EP96203060 1996-11-04
EP97200168 1997-01-22
EP97200168 1997-01-22
PCT/EP1997/002323 WO1997041209A1 (en) 1996-04-29 1997-04-29 Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits

Publications (1)

Publication Number Publication Date
AU2892997A true AU2892997A (en) 1997-11-19

Family

ID=27237546

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28929/97A Abandoned AU2892997A (en) 1996-04-29 1997-04-29 Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits

Country Status (6)

Country Link
EP (1) EP0907722A1 (en)
JP (1) JP2000508919A (en)
CN (1) CN1217746A (en)
AU (1) AU2892997A (en)
CA (1) CA2252524A1 (en)
WO (1) WO1997041209A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511732A (en) 1996-10-11 2002-04-16 ザ・テキサス・エイ・アンド・エム・ユニヴァーシティ・システム Compositions and methods for generating transgenic animals
WO1999027076A1 (en) * 1997-11-25 1999-06-03 Arc Genomic Research Pluripotent embryonic stem cells and methods of obtaining them
IL136347A0 (en) * 1997-11-25 2001-05-20 Arc Genomic Res Pluripotent embryonic stem cells and methods of obtaining them
US6238922B1 (en) * 1999-02-26 2001-05-29 Stemcells, Inc. Use of collagenase in the preparation of neural stem cell cultures
ATE293159T1 (en) 1999-12-14 2005-04-15 Thermo Biostar Inc STABILIZING DILUENT FOR POLYPEPTIDES AND ANTIGENS
CA2411914C (en) * 2000-06-20 2012-08-21 Es Cell International Pte Ltd Method of controlling differentiation of embryonic stem (es) cells by culturing es cells in the presence of bmp-2 pathway antagonists
DE60044301D1 (en) 2000-12-22 2010-06-10 Agronomique Inst Nat Rech Position-independent and tissue-specific expression of a transgene in the milk of a transgenic animal
FR2834518B1 (en) * 2002-01-10 2005-03-18 Agronomique Inst Nat Rech METHOD FOR NUCLEAR CLONING IN RABBITS AND USES
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
CA2782596A1 (en) * 2009-12-01 2011-06-09 National Cancer Center Method for constructing chimeric rat using rat embryonic stem cells
EP2511366A4 (en) 2009-12-09 2014-04-30 Univ Kyoto Agent for promoting differentiation of pluripotent stem cells into cardiac muscle cells which includes nitrovin
ES2727738T3 (en) 2010-06-11 2019-10-18 Regeneron Pharma Production of fertile xy female animals from cells is xy
US9499790B2 (en) 2010-08-26 2016-11-22 Kyoto University Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
CN103209968B (en) 2010-08-26 2015-08-05 国立大学法人京都大学 Pluripotent stem cell cardiomyocyte differentiation-promagent agent
JP6274510B2 (en) 2012-01-27 2018-02-07 国立大学法人京都大学 Method for inducing myocardial differentiation of pluripotent stem cells
EP2814950A1 (en) 2012-02-13 2014-12-24 Gamida-Cell Ltd. Mesenchymal stem cells conditioned medium and methods of generating and using the same
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US10196609B2 (en) 2013-03-08 2019-02-05 Kyoto University Composition for promoting cardiac differentiation of pluripotent stem cell comprising EGFR inhibitor
WO2015037706A1 (en) 2013-09-13 2015-03-19 国立大学法人京都大学 Compound promoting differentiation of pluripotent stem cells into cardiomyocytes
JP6651218B2 (en) 2014-05-30 2020-02-19 国立大学法人京都大学 Induction of myocardial differentiation of pluripotent stem cells using low molecular weight compounds
SG10201911411YA (en) 2014-06-26 2020-02-27 Regeneron Pharma Methods and compositions for targeted genetic modifications and methods of use
SG10201913789VA (en) 2015-09-17 2020-03-30 Regeneron Pharma Selection of pluripotent cells for production of fertile xy female mice
WO2017159862A1 (en) 2016-03-18 2017-09-21 国立大学法人京都大学 Freezing method for aggregates of pluripotent stem cell-derived myocardial cells
CN109609446B (en) * 2018-11-14 2020-11-03 广西大学 Culture solution and method for isolated culture of rabbit embryonic stem cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166065A (en) * 1988-08-04 1992-11-24 Amrad Corporation Limited In vitro propagation of embryonic stem cells
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods

Also Published As

Publication number Publication date
CA2252524A1 (en) 1997-11-06
WO1997041209A1 (en) 1997-11-06
CN1217746A (en) 1999-05-26
JP2000508919A (en) 2000-07-18
EP0907722A1 (en) 1999-04-14

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