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AU2001239827A1 - Substituted alkylene diamine compounds - Google Patents

Substituted alkylene diamine compounds

Info

Publication number
AU2001239827A1
AU2001239827A1 AU2001239827A AU3982701A AU2001239827A1 AU 2001239827 A1 AU2001239827 A1 AU 2001239827A1 AU 2001239827 A AU2001239827 A AU 2001239827A AU 3982701 A AU3982701 A AU 3982701A AU 2001239827 A1 AU2001239827 A1 AU 2001239827A1
Authority
AU
Australia
Prior art keywords
substituted alkylene
diamine compounds
alkylene diamine
compounds
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001239827A
Inventor
Elfatih Elzein
Tim Marquart
Jeff Zablocki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead Palo Alto Inc
Original Assignee
CV Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CV Therapeutics Inc filed Critical CV Therapeutics Inc
Publication of AU2001239827A1 publication Critical patent/AU2001239827A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2001239827A 2000-02-22 2001-02-22 Substituted alkylene diamine compounds Abandoned AU2001239827A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18413200P 2000-02-22 2000-02-22
US60184132 2000-02-22
PCT/US2001/005655 WO2001062711A2 (en) 2000-02-22 2001-02-22 Substituted alkylene diamine compounds

Publications (1)

Publication Number Publication Date
AU2001239827A1 true AU2001239827A1 (en) 2001-09-03

Family

ID=22675672

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001239827A Abandoned AU2001239827A1 (en) 2000-02-22 2001-02-22 Substituted alkylene diamine compounds

Country Status (3)

Country Link
US (1) US6638970B2 (en)
AU (1) AU2001239827A1 (en)
WO (1) WO2001062711A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL159897A0 (en) * 2001-07-19 2004-06-20 Cv Therapeutics Inc Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
CA2508608A1 (en) * 2002-12-05 2004-06-24 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
EP1806346B1 (en) * 2002-12-05 2009-07-22 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
ATE443058T1 (en) * 2003-01-03 2009-10-15 Cv Therapeutics Inc SUBSTITUTED HETEROCYCLIC COMPOUNDS
JP2006515891A (en) * 2003-01-17 2006-06-08 シーブイ・セラピューティクス・インコーポレイテッド Substituted heterocyclic compounds effective for the treatment of cardiovascular diseases
WO2005000826A1 (en) * 2003-06-23 2005-01-06 Cv Therapeutics, Inc. Urea derivatives of piperazines and piperidines as fatty acid oxidation inhibitors
EP1789407A2 (en) * 2004-09-08 2007-05-30 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
WO2007053415A2 (en) * 2005-11-01 2007-05-10 Novartis Vaccines And Diagnostics Inc. Agents for the treatment of cardiac arrhythmias
US20100303753A1 (en) * 2007-10-19 2010-12-02 Nektar Therapeutics Oligomer Conjugates of Lidocaine and Its Derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2267104A1 (en) 1974-04-12 1975-11-07 Ferlux Labo Sa Hypotensive and antiarrhythmic piperazines - 1-(3-phenoxy-2-hydroxy propyl)-4-substd. piperazines
GB1540463A (en) 1976-10-07 1979-02-14 Ici Ltd Alkanolamine derivatives
US4766125A (en) 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
US4567264A (en) 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
ATE142497T1 (en) * 1989-06-23 1996-09-15 Syntex Inc RANOLAZINE AND RELATED PIPERAZINES FOR THE TREATMENT OF TISSUES AFFECTED BY PHYSICAL OR CHEMICAL DAMAGE
US5527545A (en) 1989-09-18 1996-06-18 Recordati S.A. Chemical And Pharmaceutical Company Liquid-suspension controlled-release pharmaceutical composition
JPH03141258A (en) 1989-10-25 1991-06-17 Kowa Co Novel piperazine derivative
DK203990D0 (en) 1990-08-24 1990-08-24 Novo Nordisk As piperazinyl
HU209723B (en) 1990-10-31 1994-10-28 Richter Gedeon Vegyeszet Process for producing of piperazine derivatives
US5455045A (en) 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations

Also Published As

Publication number Publication date
WO2001062711A3 (en) 2002-02-14
US20010036961A1 (en) 2001-11-01
WO2001062711A2 (en) 2001-08-30
US6638970B2 (en) 2003-10-28

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