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AU2001244618A1 - Substituted 1,3-thiazole compounds, their production and use - Google Patents

Substituted 1,3-thiazole compounds, their production and use

Info

Publication number
AU2001244618A1
AU2001244618A1 AU2001244618A AU4461801A AU2001244618A1 AU 2001244618 A1 AU2001244618 A1 AU 2001244618A1 AU 2001244618 A AU2001244618 A AU 2001244618A AU 4461801 A AU4461801 A AU 4461801A AU 2001244618 A1 AU2001244618 A1 AU 2001244618A1
Authority
AU
Australia
Prior art keywords
substituted
production
thiazole compounds
thiazole
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001244618A
Inventor
Hiroyuki Kimura
Seiji Miwatashi
Ken-Ichi Naruo
Shigenori Ohkawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of AU2001244618A1 publication Critical patent/AU2001244618A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2001244618A 2000-03-30 2001-03-29 Substituted 1,3-thiazole compounds, their production and use Abandoned AU2001244618A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2000-097876 2000-03-30
JP2000097876 2000-03-30
JP2001-027571 2001-02-02
JP2001027571 2001-02-02
PCT/JP2001/002629 WO2001074811A2 (en) 2000-03-30 2001-03-29 Substituted 1,3-thiazole compounds, their production and use

Publications (1)

Publication Number Publication Date
AU2001244618A1 true AU2001244618A1 (en) 2001-10-15

Family

ID=26589144

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001244618A Abandoned AU2001244618A1 (en) 2000-03-30 2001-03-29 Substituted 1,3-thiazole compounds, their production and use

Country Status (5)

Country Link
US (1) US7495018B2 (en)
EP (1) EP1268474A2 (en)
AU (1) AU2001244618A1 (en)
CA (1) CA2404384A1 (en)
WO (1) WO2001074811A2 (en)

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CA2444487A1 (en) * 2001-05-18 2002-11-28 Endacea Inc. Methods and formulations of using a1 adenosine and p2x purinoreceptor antagonists
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
WO2004018463A2 (en) 2002-08-23 2004-03-04 Rigel Pharmaceuticals, Inc. Pyridyl substituted heterocycles useful for treating or preventing hcv infection
DE60331367D1 (en) 2002-12-30 2010-04-01 Angiotech Int Ag ACTIVE COMPOSITION OF FAST GELING POLYMERIC COMPOSITION
WO2004071440A2 (en) * 2003-02-06 2004-08-26 Bristol-Myers Squibb Company Thiazolyl-based compounds useful as kinase inhibitors
EP1620412A2 (en) 2003-05-02 2006-02-01 Rigel Pharmaceuticals, Inc. Heterocyclic compounds and hydro isomers thereof
US20050106230A1 (en) * 2003-11-17 2005-05-19 Young Janel E. Drug-enhanced adhesion prevention
US7410979B2 (en) 2003-11-19 2008-08-12 Rigel Pharmaceuticals, Inc. Synergistically effective combinations of dihaloacetamide compounds and interferon or ribavirin against HCV infections
ES2629414T3 (en) * 2003-12-26 2017-08-09 Kyowa Hakko Kirin Co., Ltd. Thiazole derivatives
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
WO2006020767A2 (en) 2004-08-13 2006-02-23 Genentech, Inc. Thiazole based inhibitors of atp-utilizing enzymes
CA2587791C (en) 2004-12-06 2012-03-13 Avigen, Inc. Method for treating neuropathic pain and associated syndromes
AU2006217742A1 (en) * 2005-02-25 2006-08-31 Kudos Pharmaceuticals Limited Hydrazinomethyl, HYDR zonomethyl and 5-membered heterocylic compounds which act as MTOR inhibitors and their use as anti cancer agents
WO2007027230A2 (en) 2005-05-02 2007-03-08 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
WO2006137658A1 (en) * 2005-06-20 2006-12-28 Dongbu Hitek Co., Ltd. New substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppression and inflammation inhibitory acitivity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and pharmaceutical composition comprising the same
WO2006137527A1 (en) 2005-06-23 2006-12-28 Kyowa Hakko Kogyo Co., Ltd. Thiazole derivative
TWI457125B (en) * 2005-08-02 2014-10-21 A prophylactic agent for for sleep disorders
UA90038C2 (en) * 2005-12-13 2010-03-25 Кадила Хелткере Лимитед SULFOXIMINE DERIVATIVES AS p38 MAP KINASE INHIBITORS
ES2389062T3 (en) * 2006-01-18 2012-10-22 Amgen, Inc Thiazole compounds as protein kinase B inhibitors (PKB)
WO2007087427A2 (en) * 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Thiazole and thiadiazole compounds for inflammation and immune-related uses
AR062360A1 (en) 2006-08-15 2008-11-05 Novartis Ag HETEROCICLIC DERIVATIVES THAT MODULATE THE ACTIVITY OF ESTEAROIL-COA-DESATURASA
TW200815428A (en) 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators
US7618989B2 (en) 2006-08-15 2009-11-17 Wyeth Tricyclic oxazolidone derivatives useful as PR modulators
GB0701426D0 (en) * 2007-01-25 2007-03-07 Univ Sheffield Compounds and their use
EP2131841B1 (en) * 2007-01-30 2012-08-01 Avigen, Inc. Methods for treating acute pain
WO2008137012A1 (en) * 2007-05-03 2008-11-13 Avigen, Inc. Use of a glial attenuator to prevent amplified pain responses caused by glial priming
EP2173728A2 (en) 2007-07-17 2010-04-14 Amgen Inc. Heterocyclic modulators of pkb
CA2693473A1 (en) * 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
AR070429A1 (en) 2008-02-20 2010-04-07 Xenon Pharmaceuticals Inc DERIVATIVES OF 1,3 TIAZOL AS INHIBITORS OF ESTEAROIL - COA -DESATURASA
AU2012203026B2 (en) * 2008-03-21 2014-06-12 Novartis Ag Novel heterocyclic compounds and uses thereof
US8865732B2 (en) 2008-03-21 2014-10-21 Novartis Ag Heterocyclic compounds and uses thereof
US8318728B2 (en) 2008-05-14 2012-11-27 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
WO2009140517A1 (en) 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
WO2009147178A2 (en) * 2008-06-04 2009-12-10 Nycomed Gmbh Novel medical use of substituted pyridin-2-ylmethylsulphinyl-1h-benzimidazoles
EP2198710A1 (en) * 2008-12-19 2010-06-23 Bayer CropScience AG Use of 5-pyridin-4yl-(1,3) thiazoles for combating phytopathogenic fungi
WO2010132838A1 (en) * 2009-05-14 2010-11-18 Hydra Biosciences, Inc. Compounds useful for treating disorders related to trpa1
EP2308866A1 (en) 2009-10-09 2011-04-13 Bayer CropScience AG Phenylpyri(mi)dinylpyrazoles and their use as fungicides
US9242969B2 (en) 2013-03-14 2016-01-26 Novartis Ag Biaryl amide compounds as kinase inhibitors
UY36294A (en) 2014-09-12 2016-04-29 Novartis Ag COMPOUNDS AND COMPOSITIONS AS QUINASA INHIBITORS
US20190060286A1 (en) 2016-02-29 2019-02-28 University Of Florida Research Foundation, Incorpo Chemotherapeutic Methods
WO2018045906A1 (en) * 2016-09-08 2018-03-15 四川科伦博泰生物医药股份有限公司 2-acylaminothiazole derivative and preparation method therefor and use thereof
CN109715163B (en) 2016-09-19 2022-11-22 诺华股份有限公司 Therapeutic combination comprising a RAF inhibitor and an ERK inhibitor
IL311471A (en) 2017-05-02 2024-05-01 Novartis Ag Combination therapy
CN109293652B (en) * 2017-07-24 2021-10-22 四川科伦博泰生物医药股份有限公司 Substituted thiazole derivative and application thereof
GB202011996D0 (en) * 2020-07-31 2020-09-16 Adorx Therapeutics Ltd Antagonist compounds
WO2023131868A1 (en) * 2022-01-07 2023-07-13 Horizon Therapeutics Ireland Dac Heterocyclic inhibitors of glut9 for treatment of disease
GB2615307A (en) * 2022-01-28 2023-08-09 Adorx Therapeutics Ltd Antagonist compounds

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US4649146A (en) 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
JPS6110580A (en) * 1984-04-17 1986-01-18 Takeda Chem Ind Ltd 5-pyridyl-1,3-thiazole derivative, preparation thereof and pharmaceutical composition containing same
EP0149884B1 (en) * 1983-09-09 1992-12-16 Takeda Chemical Industries, Ltd. 5-pyridyl-1,3-thiazole derivatives, their production and use
DE3669160D1 (en) 1985-03-27 1990-04-05 Zenyaku Kogyo Kk Thiazolderivate.
JPS61225182A (en) 1985-03-29 1986-10-06 Zenyaku Kogyo Kk Production of thiazole derivative
US4670450A (en) 1985-11-13 1987-06-02 Merrell Dow Pharmaceuticals Inc. Cardiotonic thiazolones
DE3703435A1 (en) 1987-02-05 1988-08-18 Thomae Gmbh Dr K NEW THIAZOLES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
JPH0570446A (en) 1991-09-13 1993-03-23 Taisho Pharmaceut Co Ltd N-thiazolylsulfonamide derivative
IL104369A0 (en) 1992-01-13 1993-05-13 Smithkline Beecham Corp Novel compounds and compositions
GB9201692D0 (en) 1992-01-27 1992-03-11 Smithkline Beecham Intercredit Compounds
DE69433501T2 (en) 1993-11-08 2004-11-04 Smithkline Beecham Corp. OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES
DE69637948D1 (en) 1995-10-06 2009-07-23 Merck & Co Inc SUBSTITUTED IMIDAZOLE WITH CANCER BREATHERS AND CYTOKININHIBIEREN EFFECT
JPH1149762A (en) 1997-08-08 1999-02-23 Japan Tobacco Inc Thiazole compound
DE69821132T2 (en) 1997-10-27 2004-10-21 Takeda Chemical Industries Ltd 1,3-THIAZOLE AS ADENOSINE A3 RECEPTOR ANTAGONISTS FOR TREATING ASTHMA, ALLERGIES AND DIABETES
WO1999064418A1 (en) 1998-06-05 1999-12-16 Novartis Ag Aryl pyridinyl thiazoles
DK1180518T3 (en) * 1999-04-23 2007-05-21 Takeda Pharmaceutical 5-pyridyl-1,3-azole compounds, process for their preparation and use thereof
CA2381215A1 (en) * 1999-08-06 2001-02-15 Takeda Chemical Industries, Ltd. P38map kinase inhibitors

Also Published As

Publication number Publication date
WO2001074811A3 (en) 2002-02-07
US7495018B2 (en) 2009-02-24
EP1268474A2 (en) 2003-01-02
CA2404384A1 (en) 2001-10-11
WO2001074811A2 (en) 2001-10-11
US20040053973A1 (en) 2004-03-18

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