Nothing Special   »   [go: up one dir, main page]

ATE52510T1 - Benzo(c>-1,5-naphthyridine, ein verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel. - Google Patents

Benzo(c>-1,5-naphthyridine, ein verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.

Info

Publication number
ATE52510T1
ATE52510T1 AT86103085T AT86103085T ATE52510T1 AT E52510 T1 ATE52510 T1 AT E52510T1 AT 86103085 T AT86103085 T AT 86103085T AT 86103085 T AT86103085 T AT 86103085T AT E52510 T1 ATE52510 T1 AT E52510T1
Authority
AT
Austria
Prior art keywords
loweralkyl
naphthyridine
benzo
production
intermediate products
Prior art date
Application number
AT86103085T
Other languages
English (en)
Inventor
Lawrence L Martin
Linda L Setescak
Susan J Scott
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of ATE52510T1 publication Critical patent/ATE52510T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/282-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
AT86103085T 1985-03-13 1986-03-07 Benzo(c>-1,5-naphthyridine, ein verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel. ATE52510T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/711,327 US4652567A (en) 1985-03-13 1985-03-13 Benzo(c)-1,5-naphthyridines useful for treating a patient having drug induced memory impairment in need of memory enhancement
EP86103085A EP0197318B1 (de) 1985-03-13 1986-03-07 Benzo[c]-1,5-naphthyridine, ein Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ATE52510T1 true ATE52510T1 (de) 1990-05-15

Family

ID=24857642

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86103085T ATE52510T1 (de) 1985-03-13 1986-03-07 Benzo(c>-1,5-naphthyridine, ein verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.

Country Status (19)

Country Link
US (1) US4652567A (de)
EP (1) EP0197318B1 (de)
JP (1) JPS61212585A (de)
KR (1) KR860007255A (de)
AT (1) ATE52510T1 (de)
AU (1) AU590748B2 (de)
CA (1) CA1248108A (de)
DE (1) DE3671017D1 (de)
DK (1) DK114386A (de)
ES (4) ES8707528A1 (de)
FI (1) FI861001A (de)
GR (1) GR860681B (de)
HU (2) HU197007B (de)
IL (1) IL78117A0 (de)
NO (1) NO163489B (de)
NZ (1) NZ215439A (de)
PH (1) PH22279A (de)
PT (1) PT82187B (de)
ZA (1) ZA861837B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766217A (en) * 1984-01-13 1988-08-23 Boehringer Ingelheim Kg Preparation of 5,6-dihydro-pyrrolo[2,1-a]isoquinolines
US5202440A (en) * 1987-10-05 1993-04-13 Pfizer Inc. Certain 9-amino-2-(or 4)-oxa 1,2,3,4-tetrahydro- or 1,2,3,4,5,6,7,8-octahydro-acridines
WO1989002739A1 (en) * 1987-10-05 1989-04-06 Pfizer Inc. 4-aminopyridine derivatives
US5994367A (en) 1997-03-07 1999-11-30 The University Of North Carolina At Chapel Hill Method for treating tumors using 2-aryl-naphthyridin-4-ones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2273533A1 (fr) * 1974-06-04 1976-01-02 Ferlux Sa Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5
US4297358A (en) * 1979-01-16 1981-10-27 Ciba-Geigy Corporation Novel 4,7-phenanthroline derivatives and pharmaceutical compositions containing them and their use
BE880455A (fr) * 1979-01-22 1980-06-06 Sandoz Sa Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine

Also Published As

Publication number Publication date
AU5465886A (en) 1986-09-18
DK114386D0 (da) 1986-03-12
DK114386A (da) 1986-09-14
EP0197318A1 (de) 1986-10-15
JPS61212585A (ja) 1986-09-20
PH22279A (en) 1988-07-14
AU590748B2 (en) 1989-11-16
EP0197318B1 (de) 1990-05-09
CA1248108A (en) 1989-01-03
FI861001A (fi) 1986-09-14
PT82187A (en) 1986-04-01
NO860933L (no) 1986-09-15
ES557208A0 (es) 1987-12-01
NO163489B (no) 1990-02-26
ES8707528A1 (es) 1987-08-01
FI861001A0 (fi) 1986-03-11
US4652567A (en) 1987-03-24
ES8801269A1 (es) 1988-01-01
HU201756B (en) 1990-12-28
ES552874A0 (es) 1987-08-01
ES557768A0 (es) 1988-01-01
ZA861837B (en) 1987-06-24
DE3671017D1 (de) 1990-06-13
ES557207A0 (es) 1988-01-01
HUT40658A (en) 1987-01-28
HU197007B (en) 1989-02-28
NZ215439A (en) 1990-03-27
ES8800941A1 (es) 1987-12-01
ES8801270A1 (es) 1988-01-01
PT82187B (en) 1988-01-07
GR860681B (en) 1986-07-14
KR860007255A (ko) 1986-10-10
IL78117A0 (en) 1986-07-31

Similar Documents

Publication Publication Date Title
ATE38661T1 (de) Zwischenprodukt und verfahren zu dessen herstellung.
DE3772905D1 (de) Alpha-alkyl-4-amino-3-chinolin-methanole und 1-(4-aralkylamino-3-chinolyl)alkanone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE69025941D1 (de) Dem Physostigmin verwandte 4- und 6-Carbamate, ein Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ATE127807T1 (de) N-heteroaryl-purin-6-amine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE143020T1 (de) Aminocarbonylcarbamate verwandt mit physostigmin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE47856T1 (de) 11-substituierte 5h,11h-pyrrolo(2,1c>(1,4>benzoxazepine, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE140006T1 (de) 1-(pyrido(3,4-b>-1,4-oxazinyl-4-yl)-1h-indole, zwischenprodukte und ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE201024T1 (de) Carbamatderivate von 4-amino-3-isoxazolidinonen und 3-amino-1-hydroxypyrrolidinon-2-onen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3780015D1 (de) Kondensierte heterocyclische tetrahydroaminochinolinole und verwandte verbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE52510T1 (de) Benzo(c>-1,5-naphthyridine, ein verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE111899T1 (de) 1,2,3,4-tetrahydro-1,9-acridindiamine, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.
DE68902386D1 (de) N-pyridinyl-9h-carbazol-9-amine, verfahren zu ihrer herstellung und ihre verwendung als medikamente.
ATE171942T1 (de) 1-piperazinyl-2-butene und 2-butyne, zwischenverbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE56713T1 (de) 1,2,3,4,4a,9b-hexahydro-4aaminoalkyldibenzofurane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE151422T1 (de) 8-azabicyclo(3.2.1>octylalkylthiazolidinone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE40118T1 (de) Benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel.
ATE92074T1 (de) Beta-d-phenylthioxyloside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3483011D1 (de) Substituierte alkylamino-derivate von 6,11-dihydro-11-oxo-dibenz(b,e)-oxepin, verfahren zu ihrer herstellung, ihre zwischenprodukte und ihre verwendung als arzneimittel.
DE3851697D1 (de) 2-Amino-1,2,3,4-tetrahydroisochinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties