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ATE541564T1 - Schnell zerfallende tablette mit einem säurelabilen wirkstoff - Google Patents

Schnell zerfallende tablette mit einem säurelabilen wirkstoff

Info

Publication number
ATE541564T1
ATE541564T1 AT01999360T AT01999360T ATE541564T1 AT E541564 T1 ATE541564 T1 AT E541564T1 AT 01999360 T AT01999360 T AT 01999360T AT 01999360 T AT01999360 T AT 01999360T AT E541564 T1 ATE541564 T1 AT E541564T1
Authority
AT
Austria
Prior art keywords
active ingredient
tablet
acid
acid label
label active
Prior art date
Application number
AT01999360T
Other languages
English (en)
Inventor
Rango Dietrich
Rudolf Linder
Hartmut Ney
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE541564T1 publication Critical patent/ATE541564T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01999360T 2000-12-07 2001-12-06 Schnell zerfallende tablette mit einem säurelabilen wirkstoff ATE541564T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00126807 2000-12-07
PCT/EP2001/014340 WO2002045694A1 (en) 2000-12-07 2001-12-06 Rapidly disintegrating tablet comprising an acid-labile active ingredient

Publications (1)

Publication Number Publication Date
ATE541564T1 true ATE541564T1 (de) 2012-02-15

Family

ID=8170591

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01999360T ATE541564T1 (de) 2000-12-07 2001-12-06 Schnell zerfallende tablette mit einem säurelabilen wirkstoff

Country Status (16)

Country Link
US (1) US7147869B2 (de)
EP (1) EP1341528B1 (de)
JP (1) JP2004514737A (de)
KR (1) KR20030072555A (de)
CN (1) CN100335040C (de)
AT (1) ATE541564T1 (de)
AU (1) AU2002221939A1 (de)
BR (1) BR0115986A (de)
CA (1) CA2430829C (de)
CY (1) CY1112615T1 (de)
DK (1) DK1341528T3 (de)
ES (1) ES2380654T3 (de)
HK (1) HK1062264A1 (de)
PT (1) PT1341528E (de)
SI (1) SI1341528T1 (de)
WO (1) WO2002045694A1 (de)

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ES2375269T3 (es) * 2000-12-07 2012-02-28 Nycomed Gmbh Preparado farmacéutico en forma de una pasta que comprende un ingrediente activo l�?bil ante los �?cidos.
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
CA2430824C (en) * 2000-12-07 2012-05-08 Altana Pharma Ag Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient
EP1416922A1 (de) * 2001-07-16 2004-05-12 AstraZeneca AB Pharmazeutische formulierung mit einem protonenpumpen-inhibitor und antazida
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
NZ539542A (en) 2003-03-10 2007-09-28 Altana Pharma Ag Novel process for the preparation of roflumilast
CL2004000983A1 (es) 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
PE20050150A1 (es) 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
WO2006009602A2 (en) * 2004-06-16 2006-01-26 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
US8057820B2 (en) * 2004-10-08 2011-11-15 Mcneil-Ppc, Inc. Enteric coated aspirin granules comingled with binder
US8758814B2 (en) 2004-10-08 2014-06-24 Mcneil-Ppc, Inc. Chewable enteric coated aspirin tablets
WO2006097456A1 (en) 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
FR2885526B1 (fr) * 2005-05-13 2007-07-27 Flamel Technologies Sa Medicament oral a base d'inhibiteur de pompe a protons
CN100431526C (zh) * 2005-11-07 2008-11-12 上海艾力斯医药科技有限公司 一种酸敏感型药物的快速崩解片剂
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
KR101358528B1 (ko) * 2005-12-21 2014-02-06 바스프 에스이 급속 붕해 정제의 제조를 위한 약제학적 제형
WO2008148731A1 (de) * 2007-06-06 2008-12-11 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
US10406105B2 (en) * 2007-06-06 2019-09-10 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
BRPI0818286A2 (pt) * 2007-10-12 2020-08-11 Takeda Pharmaceuticals North America, Inc. métodos de tratamento de distúrbios gastrointestinais independente da ingestão de alimento.
DE102010011421A1 (de) * 2009-03-19 2010-09-30 Schaeffler Technologies Gmbh & Co. Kg Schaltbarer Schlepphebel eines Ventiltriebs einer Brennkraftmaschine
WO2010122583A2 (en) 2009-04-24 2010-10-28 Rubicon Research Private Limited Oral pharmaceutical compositions of acid labile substances
EP2440210A4 (de) 2009-06-12 2014-01-29 Meritage Pharma Inc Verfahren zur behandlung von magen-darm-erkrankungen
EP2544665A4 (de) * 2010-03-11 2014-01-01 Rich Vitamins Llc Schnelllösliches nährstoffpulver
EP2441446A1 (de) * 2010-10-14 2012-04-18 Deva Holding Anonim Sirketi Verwendung von Supersprengmittel in Cetylmyristat und/oder Cetylpalmitatformulierungen
EP2589378A1 (de) * 2010-10-14 2013-05-08 Deva Holding Anonim Sirketi Cetylmyristat- und/oder Cetylpalmitatteilchenbeschichtung
TW201309346A (zh) 2011-01-05 2013-03-01 Hospira Inc 噴霧乾燥萬古黴素
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

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SE9402431D0 (sv) 1994-07-08 1994-07-08 Astra Ab New tablet formulation
SI0723436T1 (en) 1994-07-08 2002-02-28 Astrazeneca Ab Multiple unit tableted dosage form i
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JP4939680B2 (ja) * 1997-05-27 2012-05-30 武田薬品工業株式会社 固形製剤
US6475510B1 (en) * 1997-12-19 2002-11-05 Smithkline Beecham Corporation Process for manufacturing bite-dispersion tablets
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
PT1121103E (pt) * 1998-05-18 2007-02-28 Takeda Pharmaceutical Comprimidos de desintegração oral compreendendo um benzimidazole
WO2000006126A1 (en) * 1998-07-28 2000-02-10 Takeda Chemical Industries, Ltd. Rapidly disintegrable solid preparation
SE9803240D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
BR0011347A (pt) * 1999-06-07 2002-03-19 Byk Gulden Lomberg Chem Fab Preparações e formas de administração compreendendo um composto ativo de ácido instável
DE19925710C2 (de) * 1999-06-07 2002-10-10 Byk Gulden Lomberg Chem Fab Neue Zubereitung und Darreichungsform enthaltend einen säurelabilen Protonenpumpenhemmer

Also Published As

Publication number Publication date
HK1062264A1 (en) 2004-10-29
PT1341528E (pt) 2012-03-20
CA2430829C (en) 2010-06-22
CN1479613A (zh) 2004-03-03
BR0115986A (pt) 2003-12-23
AU2002221939A1 (en) 2002-06-18
DK1341528T3 (da) 2012-03-26
WO2002045694A1 (en) 2002-06-13
EP1341528A1 (de) 2003-09-10
CA2430829A1 (en) 2002-06-13
US20040110661A1 (en) 2004-06-10
EP1341528B1 (de) 2012-01-18
US7147869B2 (en) 2006-12-12
JP2004514737A (ja) 2004-05-20
CY1112615T1 (el) 2016-02-10
CN100335040C (zh) 2007-09-05
ES2380654T3 (es) 2012-05-17
SI1341528T1 (sl) 2012-05-31
KR20030072555A (ko) 2003-09-15

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