Nothing Special   »   [go: up one dir, main page]

ATE361069T1 - Phytochemikalien zur behandlung von mastalgie und endometriose - Google Patents

Phytochemikalien zur behandlung von mastalgie und endometriose

Info

Publication number
ATE361069T1
ATE361069T1 AT00965317T AT00965317T ATE361069T1 AT E361069 T1 ATE361069 T1 AT E361069T1 AT 00965317 T AT00965317 T AT 00965317T AT 00965317 T AT00965317 T AT 00965317T AT E361069 T1 ATE361069 T1 AT E361069T1
Authority
AT
Austria
Prior art keywords
mastalgia
endometriosis
phytochemicals
treatment
diindolylmethane
Prior art date
Application number
AT00965317T
Other languages
English (en)
Inventor
Michael A Zeligs
Original Assignee
Bioresponse Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresponse Llc filed Critical Bioresponse Llc
Application granted granted Critical
Publication of ATE361069T1 publication Critical patent/ATE361069T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
AT00965317T 1999-09-23 2000-09-22 Phytochemikalien zur behandlung von mastalgie und endometriose ATE361069T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/404,111 US6689387B1 (en) 1999-09-23 1999-09-23 Phytochemicals for treatment of mastalgia and endometriosis

Publications (1)

Publication Number Publication Date
ATE361069T1 true ATE361069T1 (de) 2007-05-15

Family

ID=23598211

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00965317T ATE361069T1 (de) 1999-09-23 2000-09-22 Phytochemikalien zur behandlung von mastalgie und endometriose

Country Status (9)

Country Link
US (2) US6689387B1 (de)
EP (1) EP1213964B1 (de)
AT (1) ATE361069T1 (de)
AU (1) AU777588B2 (de)
CA (1) CA2383250C (de)
CZ (1) CZ301655B6 (de)
DE (1) DE60034689T2 (de)
NZ (1) NZ518021A (de)
WO (1) WO2001020990A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7384971B2 (en) * 1999-09-23 2008-06-10 Bioresponse L.L.C. Phytochemicals for the treatment of cervical dysplasia
US6689387B1 (en) * 1999-09-23 2004-02-10 Bioresponse Llc Phytochemicals for treatment of mastalgia and endometriosis
US20020147155A1 (en) * 2001-04-06 2002-10-10 Foster Warren G. Prevention and treatment of endometriosis with aryl hydrocarbon receptor binding ligands
US7348352B2 (en) * 2001-10-23 2008-03-25 Bioresponse L.L.C. Diindolylmethane for the treatment of HPV infection
EP1603535A4 (de) * 2003-03-18 2008-10-15 Ethicon Inc Aromatase-hemmer-diagnose und therapie
WO2005107747A2 (en) * 2004-05-06 2005-11-17 Bioresponse, Llc Diindolymethane formulations for the treatment of leiomyomas
US8449867B2 (en) 2004-08-31 2013-05-28 Stiefel Research Australia Pty Ltd Microemulsion and sub-micron emulsion process and compositions
JP4972553B2 (ja) * 2004-08-31 2012-07-11 スティーフェル リサーチ オーストラリア プロプライエタリー リミテッド マイクロエマルジョン及びサブミクロンエマルジョンの製造法及び組成物
US20150005360A1 (en) 2004-10-25 2015-01-01 Nse Products, Inc. Phytoestrogen compositions and associated methods
WO2006068759A2 (en) * 2004-11-22 2006-06-29 Magellan Companies, Inc. Liposomes containing phytochemical agents and methods for making and using same
DE602005026328D1 (de) 2004-12-30 2011-03-24 Bioresponse Llc Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus
US20060240051A1 (en) * 2005-04-26 2006-10-26 Singleton Andy H Eutectic blends containing a water soluble vitamin derivative
US20070027107A1 (en) * 2005-07-29 2007-02-01 Curt Hendrix Compositions and methods for treating estrogen-dependent diseases and conditions
US20070184117A1 (en) * 2005-08-03 2007-08-09 Stephen Gregory Tocopheryl polyethylene glycol succinate powder and process for preparing same
BRPI0717753B1 (pt) * 2006-10-27 2022-04-12 Bioresponse, Llc Uso de uma composição compreendendo 50-250 mg de um ou mais indóis relacionados com dim e um ou mais agentes anti-protozoários, e, composição
US20090324705A1 (en) * 2008-02-13 2009-12-31 Nina Vikhrieva Phytonutrient compositions for topical use
ES2396946T3 (es) 2008-03-20 2013-03-01 Virun, Inc. Emulsiones que comprenden un derivado de PEG de tocoferol
DE202008012041U1 (de) 2008-09-10 2008-11-27 Kisselew, Wsewolod Iwanowitsch Vaginalzäpfchen auf Basis von 3,3'-Dindolylmethan (Methindol)
US9320295B2 (en) * 2010-03-23 2016-04-26 Virun, Inc. Compositions containing non-polar compounds
RU2419426C1 (ru) 2010-04-26 2011-05-27 Всеволод Иванович Киселев Лекарственное средство на основе дииндолилметана (dim) с повышенной биодоступностью и его использование в лечении гиперпластических и воспалительных заболеваний человека
RU2456987C1 (ru) * 2011-03-21 2012-07-27 Сергей Владимирович Енгашев Способ получения желатиновых капсул на основе 3,31- дииндолилметана
CN102895227A (zh) * 2012-09-28 2013-01-30 达瑞医药香港有限公司 3,3’-二吲哚甲烷在制备治疗乳痛症的药物中的应用
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
RU2537025C1 (ru) * 2013-05-28 2014-12-27 Всеволод Иванович Киселев Лекарственное средство на основе дииндолилметана и его применение для лечения гриппа и респираторных вирусных инфекций
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
RU2552332C1 (ru) * 2014-07-07 2015-06-10 Закрытое акционерное общество "ИльмиксГрупп" (ЗАО "ИльмиксГрупп") Способ лечения плоскоклеточных интраэпителиальных поражений шейки матки
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
EP3280398A4 (de) 2015-04-10 2018-12-12 Bioresponse LLC Selbstemulgierende formulierungen aus dim-assoziierten indolen
RU2601893C1 (ru) * 2015-11-30 2016-11-10 Всеволод Иванович Киселев Лекарственное средство на основе индол-3-карбинола с повышенной эпигенетической активностью
RU2666242C1 (ru) * 2017-05-29 2018-09-06 Акционерное общество "МираксБиоФарма" ("MiraxBioPharma") Пероральная лекарственная форма 3,3'-дииндолилметана
RU2740377C1 (ru) * 2020-03-18 2021-01-13 Всеволод Иванович Киселёв Способ лечения эндометриоза и сопутствующего спаечного процесса лекарственным средством на основе 3,3'-дииндолилметана в комплексе с B-циклодекстрином
RU2745687C1 (ru) * 2020-05-19 2021-03-30 Всеволод Иванович Киселев Способ лечения эндометриоза с болевым синдромом и фармацевтическая композиция для его реализации
MX2023015446A (es) * 2021-06-29 2024-03-06 Ilan Chaitowitz Tratamiento de la ginecomastia y/o de la mastalgia.
BE1030538B1 (nl) 2022-05-18 2023-12-19 Bogaert Gina Van Liposomaal preparaat met ingekapselde hormonen, werkwijze voor de productie en gebruik ervan

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ252051A (en) * 1992-05-19 1996-10-28 Graham Edmund Kelly Health supplement comprising a phyto-oestrogen selected from genistein, daidzein, biochanin and/or formononetin
US5981568A (en) * 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5948808A (en) * 1997-03-07 1999-09-07 The Texas A&M University System Indole-3-carbinol, diindolylmethane and substituted analogs as antiestrogens
US6001868A (en) * 1997-05-30 1999-12-14 The Regents Of The University Of California Indole-3-carbinol (I3C) derivatives and methods
US5895787A (en) * 1997-10-08 1999-04-20 Designed Nutritional Products, Inc. Treatment of fibromyalgia and related disorders
US6086915A (en) * 1998-04-01 2000-07-11 Bioresponse L.L.C. Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
US5993887A (en) * 1998-06-29 1999-11-30 Bioavailability Systems, L.L.C. Safe citrus juice and process for preparation
US6613792B1 (en) * 1999-08-02 2003-09-02 Designed Nutritional Products, Inc. Treatment of premenstrual syndrome and menopause
US7384971B2 (en) * 1999-09-23 2008-06-10 Bioresponse L.L.C. Phytochemicals for the treatment of cervical dysplasia
US6689387B1 (en) * 1999-09-23 2004-02-10 Bioresponse Llc Phytochemicals for treatment of mastalgia and endometriosis
US6534085B1 (en) * 1999-09-23 2003-03-18 Bioresponse L.L.C. Phytochemicals for promoting weight loss
US6399645B1 (en) * 2000-03-20 2002-06-04 Maria Bell Chemoprevention and treatment of cervical or vaginal neoplasia
US20020147155A1 (en) * 2001-04-06 2002-10-10 Foster Warren G. Prevention and treatment of endometriosis with aryl hydrocarbon receptor binding ligands
US7348352B2 (en) * 2001-10-23 2008-03-25 Bioresponse L.L.C. Diindolylmethane for the treatment of HPV infection

Also Published As

Publication number Publication date
CA2383250A1 (en) 2001-03-29
EP1213964A1 (de) 2002-06-19
AU7605300A (en) 2001-04-24
EP1213964A4 (de) 2004-05-12
EP1213964B1 (de) 2007-05-02
US6689387B1 (en) 2004-02-10
DE60034689D1 (de) 2007-06-14
NZ518021A (en) 2003-09-26
DE60034689T2 (de) 2008-01-17
US7384972B2 (en) 2008-06-10
CZ301655B6 (cs) 2010-05-12
CZ20021047A3 (cs) 2003-02-12
US20040156910A1 (en) 2004-08-12
WO2001020990A1 (en) 2001-03-29
AU777588B2 (en) 2004-10-21
CA2383250C (en) 2010-01-26

Similar Documents

Publication Publication Date Title
DE60034689D1 (de) Phytochemikalien zur behandlung von mastalgie und endometriose
RU2011138835A (ru) Применение производного рапамицина
GEP20053600B (en) 3-(4-Amidopyrrol-2-Ylmethlidene)-2- Indolinone Derivatives as Protein Kinase Inhibitors
DK1175398T3 (da) Indolinderivater som progesteronantagonister
ATE269846T1 (de) N-substituierte aminotetraline als neuropeptid y y5 rezeptor-liganden und ihre anwendung zur behandlung von fettleibigkeit und anderen erkrankungen
CO5271700A1 (es) Composicion farmaceutica que comprende acido 3-[2,4-dimetil-5-(2-oxo-1,2-dihidro-indol-3-ilidenmetil)-1h-pirrol-3-il]-propionico, uno o mas compuestos polihidrocarbilo y un vehiculo farmaceuticamente aceptable
CY1105125T1 (el) Χρηση αναστολεων ακετυλοχολινεστepασης για την παρασκευη φαρμακευτικων συνθεσεων για τη θepαπευτικη αντιμετωπιση συνδρομων λειτουργικων και/ή οργανικων πονων
TR200202466T2 (tr) Felç, diyabet ve/veya konjesif kalp yetmezliğinin önlenmesinde kullanılan farmakolojik formülasyonlar.
DE69820632D1 (de) 2-phenyl-substituierte 1-(n-phenylaminoalkyl)-piperazin-derivate
EA200500782A1 (ru) Лечение геморрагического шока
DE69929440D1 (de) Zusammensetzungen zur behandlung chronischer lymphatischer leukämie
MY136767A (en) Formulations comprising an indolinone compound
NO20004419L (no) Ny anvendelse
WO2005007102A3 (en) Phytochemicals for the treatment of mastalgia, endometriosis and hpv-related conditions including cervical dysplasia
SE9902267D0 (sv) New compounds
DK1000046T3 (da) Piperazinderivater, der er aktive på den nedre urinvejskanal
NO20031410L (no) Anvendelse av distamycinderivater for fremstilling av medikamenter
RU2001124802A (ru) Применение саредутанта и его фармацевтически приемлемых солей для приготовления лекарственных средств, применяемых для лечения или предупреждения расстройств настроения, расстройств адаптации или смешанных тревожно-депрессивных расстройств
NO983177L (no) Anvendelse av 1-enantiomeren av centkroman til fremstilling av et farmasaytisk preparat for behandling eller profylakse av brystkreft
HUP0401042A2 (hu) Primer álmatlanság kezelésére alkalmas gyógyszerkészítmények
ATE422885T1 (de) Cycloalkyläbü kondensierte indole
ATE306483T1 (de) Alkoxy-substituierte benzimidazolverbindungen , diese enthaltende arzneimittel und ihre verwendung
BG105984A (bg) Използване на озанетант за приготвяне на лекарствени средства полезни за лечение на разстройства на настроението
EA200401100A1 (ru) 1α-ФТОР-25-ГИДРОКСИ-16,23E-ДИЕН-26,27-БИСГОМО-20-ЭПИХОЛЕКАЛЬЦИФЕРОЛ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ
WO1999023070A8 (en) N-acetylserotonin derivatives and uses thereof

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties