ATE216384T1 - Thiazolylbenzofuranderivate und pharmazeutische zusammensetzungen die sie enthalten - Google Patents

Thiazolylbenzofuranderivate und pharmazeutische zusammensetzungen die sie enthalten

Info

Publication number: ATE216384T1
Authority: AT; Austria
Prior art keywords: pharmaceutical compositions; compositions containing; thiazolylbenzofuran; derivatives; optionally substituted
Prior art date: 1996-01-22

Application number

AT97900432T

Other languages

English (en)

Inventor

Masaaki Matsuo

Kazuo Okumura

Shinji Shigenaga

Hiroaki Nishimura

Hiroshi Matsuda

Daijiro Hagiwara

Tadashi Terasaka

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-22

Filing date

1997-01-17

Publication date

2002-05-15

1996-01-22 Priority claimed from GBGB9601235.6A external-priority patent/GB9601235D0/en

1996-07-18 Priority claimed from AUPO1111A external-priority patent/AUPO111196A0/en

1997-01-17 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

2002-05-15 Application granted granted Critical

2002-05-15 Publication of ATE216384T1 publication Critical patent/ATE216384T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT97900432T 1996-01-22 1997-01-17 Thiazolylbenzofuranderivate und pharmazeutische zusammensetzungen die sie enthalten ATE216384T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9601235.6A GB9601235D0 (en)	1996-01-22	1996-01-22	Novel compounds
AUPO1111A AUPO111196A0 (en)	1996-07-18	1996-07-18	Novel compounds
PCT/JP1997/000073 WO1997027190A1 (en)	1996-01-22	1997-01-17	Thiazolylbenzofuran derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
ATE216384T1 true ATE216384T1 (de)	2002-05-15

Family

ID=25645218

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT97900432T ATE216384T1 (de)	1996-01-22	1997-01-17	Thiazolylbenzofuranderivate und pharmazeutische zusammensetzungen die sie enthalten
AT01123263T ATE263561T1 (de)	1996-01-22	1997-01-17	Thiazolylbenzofuranderivate und ihre verwendung als srs-a- und leukotrien-antagonisten

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT01123263T ATE263561T1 (de)	1996-01-22	1997-01-17	Thiazolylbenzofuranderivate und ihre verwendung als srs-a- und leukotrien-antagonisten

Country Status (12)

Country	Link
US (1)	US5994378A (de)
EP (2)	EP0880519B1 (de)
JP (1)	JP2000503984A (de)
KR (1)	KR19990076788A (de)
CN (1)	CN1209809A (de)
AT (2)	ATE216384T1 (de)
CA (1)	CA2244189A1 (de)
DE (2)	DE69728581D1 (de)
EA (1)	EA199800650A1 (de)
ES (1)	ES2171878T3 (de)
HU (1)	HUP9900424A2 (de)
WO (1)	WO1997027190A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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GB9919413D0 (en) *	1999-08-18	1999-10-20	Zeneca Ltd	Chemical compounds
WO2001032621A1 (fr) *	1999-10-29	2001-05-10	Wakunaga Pharmaceutical Co., Ltd.	Nouveaux derives d'indole, et medicaments contenant lesdits derives comme principe actif
US7759373B2 (en) *	2001-04-16	2010-07-20	Mitsubishi Tanabe Pharma Corporation	Large conductance calcium-activated K channel opener
EP1424330B1 (de)	2001-08-10	2011-09-28	Nippon Chemiphar Co., Ltd.	Aktivator für den peroxisome proliferator-responsiven rezeptor delta
BRPI0213243B8 (pt)	2001-10-12	2021-05-25	Nippon Chemiphar Co	composto heterocíclico aromático contendo um anel oxazol, tiazol ou imidazol, ou um sal farmaceuticamente aceitável do mesmo, e, composição farmacêutica
US8013006B2 (en) *	2004-07-14	2011-09-06	Ptc Therapeutics, Inc.	Methods for treating hepatitis C
CN101142184A (zh) *	2004-10-12	2008-03-12	解码遗传Ehf公司	用于阻塞性动脉疾病的磺酰胺迫位取代的双环化合物
WO2006046683A1 (en) *	2004-10-25	2006-05-04	Astellas Pharma Inc.	Thiazolylbenzofuran derivatives as leukotriene and prostaglandin d2 receptor antagonists
GB2431927B (en) *	2005-11-04	2010-03-17	Amira Pharmaceuticals Inc	5-Lipoxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en)	2005-11-04	2013-03-19	Panmira Pharmaceuticals, Llc	5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en)	2005-11-04	2011-07-12	Amira Pharmaceuticals, Inc.	5-lipdxygenase-activating protein (FLAP) inhibitors
CA2642668C (en) *	2006-02-15	2013-01-08	Allergan, Inc.	Indole-3-carboxylic acid amide and ester compounds bearing phenyl groups having sphingosine-1-phosphate (s1p) receptor antagonist biological activity
CN101460458A (zh) *	2006-02-15	2009-06-17	阿勒根公司	具有1－磷酸－鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚－3－羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物
PT2014652E (pt)	2006-04-18	2014-11-12	Nippon Chemiphar Co	Agente de ativação para o recetor ativado por proliferador de peroxissoma
DE102006021733A1 (de) *	2006-05-09	2007-11-22	Bayer Healthcare Ag	3-Tetrazolylindazole und 3-Tetrazolylpyrazolopyridine sowie ihre Verwendung
RU2008149518A (ru) *	2006-05-16	2010-06-27	Декод Дженетикс, Ехф. (Is)	Способ получения 7-(акрилоил) индолов
DE102006043443A1 (de) *	2006-09-15	2008-03-27	Bayer Healthcare Ag	Neue aza-bicyclische Verbindungen und ihre Verwendung
US8524917B2 (en)	2007-01-11	2013-09-03	Allergan, Inc.	6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity
KR20090101307A (ko)	2007-01-11	2009-09-24	알러간, 인코포레이티드	스핑고신-1-포스페이트(ｓ1ｐ) 수용체 길항제 생물학적 활성을 갖는 6-치환된 인돌-3-카르복실산 아미드 화합물
PT2277874T (pt)	2008-04-15	2018-08-10	Nippon Chemiphar Co	Ativador para recetor ativado por proliferador de peroxissoma
DE102008063992A1 (de)	2008-12-19	2010-09-02	Lerner, Zinoviy, Dipl.-Ing.	Neue aliphatisch substituierte Pyrazolopyridine und ihre Verwendung
EP2544679B1 (de)	2010-03-12	2019-05-15	Omeros Corporation	Pde10-hemmer sowie entsprechende zusammensetzungen und verfahren
EP2655362A1 (de)	2010-12-22	2013-10-30	Abbvie Inc.	Hepatitis-c-inhibitoren und ihre verwendung
JP6386478B2 (ja)	2013-02-21	2018-09-05	アドヴェリオ・ファーマ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	メチル｛４，６−ジアミノ−２−［１−（２−フルオロベンジル）−１ｈ−ピラゾロ［３，４−ｂ］ピリジノ−３−イル］ピリミジノ−５−イル｝メチルカルバメートの形態
NZ630810A (en)	2014-04-28	2016-03-31	Omeros Corp	Processes and intermediates for the preparation of a pde10 inhibitor
NZ716462A (en)	2014-04-28	2017-11-24	Omeros Corp	Optically active pde10 inhibitor
KR102586736B1 (ko)	2014-08-29	2023-10-11	씨에이치디아이 파운데이션, 인코포레이티드	헌팅틴을 단백질 영상화하기 위한 프로브
JP2018513153A (ja)	2015-04-24	2018-05-24	オメロスコーポレーション	Ｐｄｅ１０インヒビターならびに関連する組成物および方法
US9920045B2 (en)	2015-11-04	2018-03-20	Omeros Corporation	Solid state forms of a PDE10 inhibitor
JP7006990B2 (ja)	2017-11-17	2022-02-10	セリックスバイオプライヴェートリミテッド	眼障害の処置のための組成物及び方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2600644B2 (ja) *	1991-08-16	1997-04-16	藤沢薬品工業株式会社	チアゾリルベンゾフラン誘導体
JPH07179856A (ja) *	1993-12-21	1995-07-18	Canon Inc	液晶性化合物、これを含有する液晶組成物、該液晶組成物を用いた液晶素子並びにこれらを用いた表示方法、表示装置

1997
- 1997-01-17 EP EP97900432A patent/EP0880519B1/de not_active Expired - Lifetime
- 1997-01-17 ES ES97900432T patent/ES2171878T3/es not_active Expired - Lifetime
- 1997-01-17 KR KR1019980704913A patent/KR19990076788A/ko not_active Application Discontinuation
- 1997-01-17 AT AT97900432T patent/ATE216384T1/de not_active IP Right Cessation
- 1997-01-17 EP EP01123263A patent/EP1170009B1/de not_active Expired - Lifetime
- 1997-01-17 DE DE69728581T patent/DE69728581D1/de not_active Expired - Lifetime
- 1997-01-17 JP JP9526720A patent/JP2000503984A/ja not_active Ceased
- 1997-01-17 AT AT01123263T patent/ATE263561T1/de not_active IP Right Cessation
- 1997-01-17 US US09/101,766 patent/US5994378A/en not_active Expired - Fee Related
- 1997-01-17 CN CN97191798A patent/CN1209809A/zh active Pending
- 1997-01-17 WO PCT/JP1997/000073 patent/WO1997027190A1/en not_active Application Discontinuation
- 1997-01-17 HU HU9900424A patent/HUP9900424A2/hu unknown
- 1997-01-17 EA EA199800650A patent/EA199800650A1/ru unknown
- 1997-01-17 DE DE69712042T patent/DE69712042T2/de not_active Expired - Fee Related
- 1997-01-17 CA CA002244189A patent/CA2244189A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2244189A1 (en)	1997-07-31
DE69728581D1 (de)	2004-05-13
KR19990076788A (ko)	1999-10-15
ES2171878T3 (es)	2002-09-16
EP1170009A3 (de)	2002-01-16
DE69712042T2 (de)	2002-10-02
DE69712042D1 (de)	2002-05-23
EP1170009A2 (de)	2002-01-09
EA199800650A1 (ru)	1999-02-25
HUP9900424A2 (hu)	1999-05-28
EP0880519A1 (de)	1998-12-02
ATE263561T1 (de)	2004-04-15
JP2000503984A (ja)	2000-04-04
WO1997027190A1 (en)	1997-07-31
CN1209809A (zh)	1999-03-03
EP0880519B1 (de)	2002-04-17
EP1170009B1 (de)	2004-04-07
US5994378A (en)	1999-11-30

Publication	Publication Date	Title
ATE216384T1 (de)	2002-05-15	Thiazolylbenzofuranderivate und pharmazeutische zusammensetzungen die sie enthalten
BG92804A (bg)	1993-12-24	4-бензоилизоксазолови производни
AR029383A1 (es)	2003-06-25	Moleculas pequenas, los intermediarios para su sintesis, las composiciones farmaceuticas que las contienen y su uso para preparar un medicamento destinado al tratamiento o la profilaxis de enfermedades inflamatorias o mediadas por celulas inmunes
NO882241L (no)	1988-11-23	Tetrazolmellomprodukter for fremstilling av antihypertensive forbindelser.
PL326203A1 (en)	1998-08-31	(methylsulphonyl)phenyl-2-(5)-furanones as cox-2 inhibitors
NZ236589A (en)	1993-02-25	A-nor-steroid-3-carboxylic acid derivatives and pharmaceutical compositions
ATE311188T1 (de)	2005-12-15	Kombination eines angiotensin-ii antagonistisch wirkenden benzimidazols mit manidipin zur behandlung von bluthochdruck
PT896533E (pt)	2004-02-27	Pentafluorobenzenosulfonamidas e analogos
DE69108138D1 (de)	1995-04-20	Imidazopyridinderivate und ihre Verwendung.
YU13396A (sh)	1999-06-15	N-(3-benzofuranil) urea derivati, postupci za njihovo dobijanje, kompozicije koje ih sadrže i njihova upotreba u lekovima
FI920023A0 (fi)	1992-01-03	Heteroarylpiperazinfoereningar som antipsykotiska aemnen.
RU94038064A (ru)	1997-05-27	Производные пиперазина и пиперидина, их применение в качестве противопсихотических средств, способ их получения фармацевтическая композиция
DE602004020463D1 (de)	2009-05-20	Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthalten
MA28286A1 (fr)	2006-11-01	Dérivés de 1-N-phenyl-amino-1H-imidazole et compositions pharmaceutiques les contenant
MD1560F2 (en)	2000-11-30	Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
MA21902A1 (fr)	1991-04-01	Procede pour la preparation de peptitides hemoregulateurs et des compositions pharmaceutiques les comtenant .
ATE342261T1 (de)	2006-11-15	Pyranderivate als inhibitoren von ace und nep
IL107321A0 (en)	1994-01-25	Substituted azetidinones, their preparation and pharmaceutical compositions comprising them
AU2008995A (en)	1995-11-23	Improvements in or relating to organic compounds
FR2791262B1 (fr)	2001-09-28	Compositions a base de chondroitine et de chitosan pour la protection, le traitement ou le remplacement des tissus conjonctifs
ES2076838T3 (es)	1995-11-01	Nuevo derivado de la isoindolinona, su preparacion y las composiciones farmaceuticas que le contienen.
NO895165L (no)	1989-12-21	Pyrazolopyridin-type mevalono-laktoner.
YU17999A (sh)	2002-03-18	Novi derivati pentaeritrita, njihova izrada i primena kao i međuproizvodi za njihovu sintezu
ATE88176T1 (de)	1993-04-15	2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
KR950701222A (ko)	1995-03-23	이식 조직의 거부반응 억제제 및 il-1 생산 억제제

Legal Events

Date	Code	Title	Description
2002-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties