ATE208381T1 - Verfahren zur herstellung von taxol und seiner derivate - Google Patents
Verfahren zur herstellung von taxol und seiner derivateInfo
- Publication number
- ATE208381T1 ATE208381T1 AT96920783T AT96920783T ATE208381T1 AT E208381 T1 ATE208381 T1 AT E208381T1 AT 96920783 T AT96920783 T AT 96920783T AT 96920783 T AT96920783 T AT 96920783T AT E208381 T1 ATE208381 T1 AT E208381T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- compound
- aryl
- heteroaryl
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9512471.5A GB9512471D0 (en) | 1995-06-20 | 1995-06-20 | Method for the preparation of taxol and its derivatives |
| PCT/EP1996/002409 WO1997000870A1 (en) | 1995-06-20 | 1996-06-04 | Method for the preparation of taxol and its derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE208381T1 true ATE208381T1 (de) | 2001-11-15 |
Family
ID=10776319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96920783T ATE208381T1 (de) | 1995-06-20 | 1996-06-04 | Verfahren zur herstellung von taxol und seiner derivate |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5767282A (de) |
| EP (2) | EP1116718A3 (de) |
| JP (1) | JP3889047B2 (de) |
| KR (1) | KR970705552A (de) |
| CN (1) | CN1179955C (de) |
| AT (1) | ATE208381T1 (de) |
| AU (1) | AU712898B2 (de) |
| CA (1) | CA2197467C (de) |
| DE (1) | DE69616719T2 (de) |
| ES (1) | ES2168489T3 (de) |
| GB (1) | GB9512471D0 (de) |
| HU (1) | HUP9702399A3 (de) |
| IL (1) | IL120165A (de) |
| MX (1) | MX9701274A (de) |
| NO (1) | NO970766L (de) |
| WO (1) | WO1997000870A1 (de) |
| ZA (1) | ZA964951B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150537A (en) * | 1997-12-12 | 2000-11-21 | Emory University | Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents |
| WO2000047434A1 (en) | 1999-02-10 | 2000-08-17 | Erik Zapletal | Balanced suspension system |
| IT1308636B1 (it) * | 1999-03-02 | 2002-01-09 | Indena Spa | Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii. |
| JP2002541014A (ja) | 1999-04-12 | 2002-12-03 | キネティック プロプライエタリー リミテッド | 車輌サスペンションシステム用の能動的乗り心地制御 |
| EP1229934B1 (de) | 1999-10-01 | 2014-03-05 | Immunogen, Inc. | Zusammensetzungen und verfahren zur behandlung von krebs mittels immunkonjugaten und chemotherapeutischen agenzien |
| US6143900A (en) * | 1999-10-26 | 2000-11-07 | Dong Kook Pharmaceutical Co., Ltd. | Stereoselective synthesis of oxazoline derivative |
| PL194032B1 (pl) * | 2002-12-19 | 2007-04-30 | Agropharm Sa | Sposób wytwarzania półproduktów użytecznych w syntezie paklitakselu |
| CN101020672B (zh) * | 2006-12-28 | 2010-08-25 | 上海百灵医药科技有限公司 | 多烯紫杉醇的合成方法 |
| CN101007795B (zh) * | 2007-01-26 | 2010-08-18 | 浙江大学 | 紫杉醇及多烯紫杉醇的合成方法 |
| CN115260130A (zh) * | 2022-07-07 | 2022-11-01 | 上海卓鼎生物技术有限公司 | 一种10-脱乙酰基紫杉醇的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9102128A (es) * | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
| FR2687151B1 (fr) * | 1992-02-07 | 1994-03-25 | Rhone Poulenc Rorer Sa | Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2696458B1 (fr) * | 1992-10-05 | 1994-11-10 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
-
1995
- 1995-06-20 GB GBGB9512471.5A patent/GB9512471D0/en active Pending
-
1996
- 1996-06-04 ES ES96920783T patent/ES2168489T3/es not_active Expired - Lifetime
- 1996-06-04 CA CA002197467A patent/CA2197467C/en not_active Expired - Fee Related
- 1996-06-04 EP EP01201499A patent/EP1116718A3/de not_active Withdrawn
- 1996-06-04 JP JP50354397A patent/JP3889047B2/ja not_active Expired - Fee Related
- 1996-06-04 CN CNB961907630A patent/CN1179955C/zh not_active Expired - Fee Related
- 1996-06-04 MX MX9701274A patent/MX9701274A/es not_active IP Right Cessation
- 1996-06-04 KR KR1019970701092A patent/KR970705552A/ko not_active Application Discontinuation
- 1996-06-04 DE DE69616719T patent/DE69616719T2/de not_active Expired - Lifetime
- 1996-06-04 IL IL12016596A patent/IL120165A/en not_active IP Right Cessation
- 1996-06-04 AU AU62215/96A patent/AU712898B2/en not_active Ceased
- 1996-06-04 HU HU9702399A patent/HUP9702399A3/hu unknown
- 1996-06-04 US US08/776,607 patent/US5767282A/en not_active Expired - Lifetime
- 1996-06-04 WO PCT/EP1996/002409 patent/WO1997000870A1/en not_active Application Discontinuation
- 1996-06-04 EP EP96920783A patent/EP0776322B1/de not_active Expired - Lifetime
- 1996-06-04 AT AT96920783T patent/ATE208381T1/de not_active IP Right Cessation
- 1996-06-11 ZA ZA964951A patent/ZA964951B/xx unknown
-
1997
- 1997-02-19 NO NO970766A patent/NO970766L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1116718A3 (de) | 2001-08-29 |
| JPH10505360A (ja) | 1998-05-26 |
| IL120165A0 (en) | 1997-06-10 |
| DE69616719D1 (de) | 2001-12-13 |
| WO1997000870A1 (en) | 1997-01-09 |
| CN1179955C (zh) | 2004-12-15 |
| MX9701274A (es) | 1997-05-31 |
| AU6221596A (en) | 1997-01-22 |
| DE69616719T2 (de) | 2002-08-01 |
| EP0776322B1 (de) | 2001-11-07 |
| NO970766D0 (no) | 1997-02-19 |
| EP0776322A1 (de) | 1997-06-04 |
| IL120165A (en) | 2002-02-10 |
| CN1158126A (zh) | 1997-08-27 |
| HUP9702399A3 (en) | 1999-12-28 |
| AU712898B2 (en) | 1999-11-18 |
| JP3889047B2 (ja) | 2007-03-07 |
| CA2197467A1 (en) | 1997-01-09 |
| EP1116718A2 (de) | 2001-07-18 |
| HUP9702399A2 (hu) | 1998-07-28 |
| ZA964951B (en) | 1997-01-23 |
| CA2197467C (en) | 2008-02-12 |
| GB9512471D0 (en) | 1995-08-23 |
| ES2168489T3 (es) | 2002-06-16 |
| KR970705552A (ko) | 1997-10-09 |
| US5767282A (en) | 1998-06-16 |
| NO970766L (no) | 1997-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |