ATE270544T1 - Halbfeste arzneizubereitung enthaltend isotretinoin - Google Patents
Halbfeste arzneizubereitung enthaltend isotretinoinInfo
- Publication number
- ATE270544T1 ATE270544T1 AT01969090T AT01969090T ATE270544T1 AT E270544 T1 ATE270544 T1 AT E270544T1 AT 01969090 T AT01969090 T AT 01969090T AT 01969090 T AT01969090 T AT 01969090T AT E270544 T1 ATE270544 T1 AT E270544T1
- Authority
- AT
- Austria
- Prior art keywords
- semi
- preparation containing
- medicinal preparation
- solid medicinal
- isotretinoin
- Prior art date
Links
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 title abstract 2
- 229960005280 isotretinoin Drugs 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE0000111 | 2000-09-22 | ||
| PCT/BE2001/000163 WO2002024172A1 (en) | 2000-09-22 | 2001-09-21 | Pharmaceutical semi-solid composition of isotretinoin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE270544T1 true ATE270544T1 (de) | 2004-07-15 |
Family
ID=3862550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01969090T ATE270544T1 (de) | 2000-09-22 | 2001-09-21 | Halbfeste arzneizubereitung enthaltend isotretinoin |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7435427B2 (de) |
| EP (1) | EP1318791B1 (de) |
| AT (1) | ATE270544T1 (de) |
| AU (1) | AU2001289438A1 (de) |
| BR (1) | BR102013032172A2 (de) |
| CA (1) | CA2423170A1 (de) |
| DE (1) | DE60104206T2 (de) |
| ES (1) | ES2225600T3 (de) |
| PT (1) | PT1318791E (de) |
| WO (1) | WO2002024172A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU782966B2 (en) | 1999-06-08 | 2005-09-15 | University Of Iowa Research Foundation, The | Compounds and methods to enhance RAAV transduction |
| US7435427B2 (en) | 2000-09-22 | 2008-10-14 | Galephar M/F | Pharmaceutical semi-solid composition of isotretinoin |
| ITMI20011338A1 (it) * | 2001-06-26 | 2002-12-26 | Farmatron Ltd | Composizioni farmaceutiche orali a rilascio immediato del principio attivo |
| FI20030426A (fi) * | 2003-03-24 | 2004-09-25 | Tomi Jaervinen | Syklodekstriinikompleksit |
| EP1608410A2 (de) | 2003-03-31 | 2005-12-28 | University of Iowa Research Foundation | Pharmazeutische therapie und gentherapie von krankheiten, die mit dem epithelialen natriumkanal assoziert sind |
| SE0303135D0 (sv) * | 2003-11-25 | 2003-11-25 | Lipocore Holding Ab | Controlled food effect composition |
| MX2007011250A (es) * | 2005-03-21 | 2007-11-14 | Ivax Pharmaceuticals Sro | Inhibidor de la cristalizacion y su uso en capsulas de gelatina. |
| CA2677842C (en) | 2007-02-16 | 2014-09-16 | Aska Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising microparticle oily suspension |
| WO2010109259A1 (es) * | 2009-03-26 | 2010-09-30 | Grufarcol Ltda | Métoda para preparar formulaciones de gel blando de isotretinoína líquida y la formulaciones obtenidas |
| CA2762394C (en) | 2009-05-20 | 2016-07-19 | Ranbaxy Laboratories Limited | Topical retinoid solutions |
| CN102802729A (zh) | 2009-05-20 | 2012-11-28 | 兰贝克赛实验室有限公司 | 异维a酸的液体剂型 |
| US10022348B2 (en) | 2009-05-20 | 2018-07-17 | Sun Pharmaceutical Industries Limited | Topical solution of isotretinoin |
| US9078925B2 (en) * | 2012-06-18 | 2015-07-14 | Galephar Pharmaceutical Research, Inc. | Pharmaceutical semi-solid composition of isotretinoin |
| WO2015047769A1 (en) | 2013-09-25 | 2015-04-02 | 3M Innovative Properties Company | Compositions for electric field grading |
| EP3094635B1 (de) | 2014-01-17 | 2018-07-04 | Oncoral Pharma ApS | Oral anzuwendende feste darreichungsform von irinotecan zur behandlung von krebs |
| MX2016015465A (es) | 2014-05-29 | 2017-03-27 | Sun Pharmaceutical Ind Ltd | Composicion farmaceutica oral de isotretinoina. |
| WO2015186039A1 (en) * | 2014-06-02 | 2015-12-10 | Sun Pharmaceutical Industries Limited | Oral pharmaceutical composition of isotretinoin |
| JP2017521470A (ja) | 2014-07-31 | 2017-08-03 | サン ファーマシューティカル インダストリーズ リミテッドＳｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｉｎｄｕｓｔｒｉｅｓ Ｌｔｄ． | イソトレチノインの経口医薬組成物 |
| US9750711B2 (en) | 2014-10-01 | 2017-09-05 | Sun Pharmaceutical Industries Limited | Low dose oral pharmaceutical composition of isotretinoin |
| MA40781A (fr) * | 2014-10-01 | 2017-08-08 | Sun Pharmaceutical Ind Ltd | Composition pharmaceutique d'isotrétinoïne à faible dosage destinée à la voie orale |
| CA2987177A1 (en) * | 2015-05-25 | 2016-12-01 | Sun Pharmaceutical Industries Limited | Once-daily oral pharmaceutical composition of isotretinoin |
| AU2015397336A1 (en) * | 2015-05-29 | 2017-12-21 | Sun Pharmaceutical Industries Limited | Oral pharmaceutical composition of isotretinoin |
| US11702672B2 (en) | 2016-02-08 | 2023-07-18 | University Of Iowa Research Foundation | Methods to produce chimeric adeno-associated virus/bocavirus parvovirus |
| US11684679B2 (en) | 2016-03-07 | 2023-06-27 | University Of Iowa Research Foundation | AAV-mediated expression using a synthetic promoter and enhancer |
| CA3062764A1 (en) | 2016-04-28 | 2017-11-02 | Amplipharm Pharmaceuticals, LLC | Temozolomide powder formulation |
| US9949967B2 (en) | 2016-04-28 | 2018-04-24 | Amplipharm Pharmaceuticals, LLC | Temozolomide powder formulation |
| US10285987B2 (en) | 2017-04-28 | 2019-05-14 | Amplipharm Pharmaceuticals, LLC | Device and kit for dosing and dispensing non-liquid medicine |
| WO2017203365A1 (en) | 2016-05-26 | 2017-11-30 | Dr. Reddy's Laboratiories Ltd. | Pharmaceutical compositions for treating acne |
| WO2018132747A1 (en) | 2017-01-13 | 2018-07-19 | University Of Iowa Research Foundation | Bocaparvovirus small noncoding rna and uses thereof |
| CA3061125C (en) * | 2017-04-28 | 2022-05-24 | Amplipharm Pharmaceuticals, LLC | Device and kit for dosing and dispensing non-liquid medicine |
| EA202090164A1 (ru) | 2017-06-29 | 2020-05-14 | СКАЙЛАЙН БАЙОСАЙЕНСИЗ, ЭлЭлСи | Изотретиноиновые перорально-слизистые композиции и способы их применения |
| US10716774B1 (en) | 2018-01-05 | 2020-07-21 | Yale Pharmaceuticals LLC | Pharmaceutical compositions containing isotretinoin with improved dissolution profile and enhanced stability |
| EP4236915A4 (de) * | 2020-11-01 | 2024-10-23 | Idrs Labs Pvt Ltd | Orale flüssige pharmazeutische zusammensetzungen von isotretinoin |
| WO2024006748A1 (en) | 2022-07-01 | 2024-01-04 | Acrotech Biopharma Inc. | Pharmaceutical compositions comprising isotretinoin and processes for preparation and uses thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA713539B (en) | 1970-06-23 | 1972-02-23 | Hoffmann La Roche | Pharmaceutical compositions |
| US4530213A (en) | 1983-06-28 | 1985-07-23 | Air Products And Chemicals, Inc. | Economical and thermally efficient cryopump panel and panel array |
| US4678663A (en) * | 1984-02-06 | 1987-07-07 | Nuetrogena Corporation | Hydroquinone composition having enhanced bio-availability and percutaneous adsorption |
| CA1282326C (en) * | 1984-12-14 | 1991-04-02 | Paul J. Jarosz | Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient |
| US5252604A (en) * | 1992-07-10 | 1993-10-12 | Hoffmann-La Roche Inc. | Compositions of retinoic acids and tocopherol for prevention of dermatitis |
| US6054136A (en) | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
| US5993858A (en) * | 1996-06-14 | 1999-11-30 | Port Systems L.L.C. | Method and formulation for increasing the bioavailability of poorly water-soluble drugs |
| US5993585A (en) * | 1998-01-09 | 1999-11-30 | Nike, Inc. | Resilient bladder for use in footwear and method of making the bladder |
| US6020003A (en) * | 1998-02-23 | 2000-02-01 | Basf Corporation | Method of making spray-dried powders with high edible-oil loadings based on non-hydrolyzed gelatin |
| FR2775597B1 (fr) | 1998-03-04 | 2001-04-20 | Gattefosse Ets Sa | Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication |
| KR100336090B1 (ko) * | 1998-06-27 | 2002-05-27 | 윤승원 | 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제 |
| PE20001227A1 (es) | 1998-10-30 | 2000-11-06 | Hoffmann La Roche | Procesos para producir una composicion de isotretinoina |
| WO2000025572A1 (en) | 1998-11-04 | 2000-05-11 | Jagjit Singh Kaurah | Improved automatic plant watering system and water level control |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| US6383471B1 (en) | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| US6624154B1 (en) * | 1999-04-23 | 2003-09-23 | Bristol-Myers Squibb Company | Compositions and methods for treatment of hyperproliferative diseases |
| AU769315B2 (en) * | 1999-08-24 | 2004-01-22 | Cellgate, Inc. | Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties |
| US6267798B1 (en) * | 2000-02-02 | 2001-07-31 | Nuflux, Llc | Composition for treating steel making slags |
| IN192188B (de) * | 2000-06-16 | 2004-03-13 | Ranbaxy Lab Ltd | |
| US7435427B2 (en) | 2000-09-22 | 2008-10-14 | Galephar M/F | Pharmaceutical semi-solid composition of isotretinoin |
| CN102802729A (zh) | 2009-05-20 | 2012-11-28 | 兰贝克赛实验室有限公司 | 异维a酸的液体剂型 |
| RU2400226C1 (ru) | 2009-06-08 | 2010-09-27 | Юрий Степанович Макляков | Способ лечения угревой болезни |
-
2001
- 2001-09-21 US US10/380,619 patent/US7435427B2/en not_active Expired - Lifetime
- 2001-09-21 AT AT01969090T patent/ATE270544T1/de not_active IP Right Cessation
- 2001-09-21 WO PCT/BE2001/000163 patent/WO2002024172A1/en active IP Right Grant
- 2001-09-21 PT PT01969090T patent/PT1318791E/pt unknown
- 2001-09-21 CA CA002423170A patent/CA2423170A1/en not_active Abandoned
- 2001-09-21 ES ES01969090T patent/ES2225600T3/es not_active Expired - Lifetime
- 2001-09-21 AU AU2001289438A patent/AU2001289438A1/en not_active Abandoned
- 2001-09-21 DE DE60104206T patent/DE60104206T2/de not_active Expired - Fee Related
- 2001-09-21 EP EP01969090A patent/EP1318791B1/de not_active Expired - Lifetime
-
2007
- 2007-08-22 US US11/892,363 patent/US8367102B2/en active Active
-
2012
- 2012-06-18 US US13/525,904 patent/US20130096196A1/en not_active Abandoned
- 2012-06-18 US US13/525,857 patent/US8952064B2/en not_active Expired - Lifetime
- 2012-12-13 US US13/713,897 patent/US9089534B2/en not_active Expired - Lifetime
-
2013
- 2013-12-13 BR BR102013032172-9A patent/BR102013032172A2/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US8367102B2 (en) | 2013-02-05 |
| US8952064B2 (en) | 2015-02-10 |
| CA2423170A1 (en) | 2002-03-28 |
| AU2001289438A1 (en) | 2002-04-02 |
| EP1318791A1 (de) | 2003-06-18 |
| US20040009225A1 (en) | 2004-01-15 |
| BR102013032172A2 (pt) | 2017-10-24 |
| US20080171084A1 (en) | 2008-07-17 |
| ES2225600T3 (es) | 2005-03-16 |
| DE60104206D1 (de) | 2004-08-12 |
| US20130217769A1 (en) | 2013-08-22 |
| US7435427B2 (en) | 2008-10-14 |
| US20130096196A1 (en) | 2013-04-18 |
| DE60104206T2 (de) | 2005-09-22 |
| US9089534B2 (en) | 2015-07-28 |
| US20130158119A1 (en) | 2013-06-20 |
| WO2002024172A1 (en) | 2002-03-28 |
| PT1318791E (pt) | 2004-11-30 |
| EP1318791B1 (de) | 2004-07-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE270544T1 (de) | Halbfeste arzneizubereitung enthaltend isotretinoin | |
| ATE293995T1 (de) | Pharmazeutische zusammensetzungen, die wirkstoffabsorptionsfördernde verbindungen enthalten | |
| BR0111016A (pt) | Composições farmacêuticas de liberação sustentada para a administração parenteral de compostos hidrófilos biologicamente ativos | |
| ATE554750T1 (de) | Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen | |
| AR021844A1 (es) | Derivados de propanolamina aril-sustituidos, procedimientos para su preparacion, medicamentos que contienen estos compuestos y su utilizacion | |
| BR9810495A (pt) | Composição farmacêutica | |
| SE0001899D0 (sv) | New compounds | |
| BR0015188A (pt) | Composições farmacêuticas | |
| EE200300033A (et) | Tsüklopentanoindoolid, nende kasutamine ravimi valmistamiseks ning neid sisaldav farmatseutiline kompositsioon | |
| DE69940769D1 (de) | Orale flüssige zusammensetzungen | |
| BR9611802A (pt) | Composições farmacêuticas | |
| BR9907647A (pt) | Composições contendo composto orgânicos | |
| BR0214679A (pt) | Composições farmacêuticas compreendendo compostos a base de vitamina d ativa | |
| HUP9901144A2 (hu) | Hatóanyagként klopidogrel és egy antitrombotikum új kombinációját tartalmazó gyógyszerkészítmények | |
| ATE302616T1 (de) | Oral anzuwendende arzneizusammensetzungen mit gesteuerter wirkstoffabgabe | |
| CY1110258T1 (el) | Υποκατεστημενα παραγωγα c-κυκλοεξυλομεθυλαμινης | |
| ATE530197T1 (de) | Medizinische zusammensetzungen zur angiogenese- therapie | |
| TR199801861T2 (xx) | Farmas�tik olarak yararl� bile�imler. | |
| ATE406161T1 (de) | Kombination aus tenofovir, ritonavir und tmc114 | |
| RS50768B (sr) | Režim doziranja i farmaceutska formulacija za urgentnu zaštitu | |
| BR9916575A (pt) | Composição farmacêutica de liberação controlada com mesilato de tilidina como substância-ativa | |
| PT1121127E (pt) | Composicoes farmaceuticas orais contendo buprenorfina | |
| DE60202590D1 (de) | 2h-1-benzopyran-derivate, prozesse zu ihrer herstellung und pharmazeutische zusammensetzungen | |
| ATE342734T1 (de) | Adenosin a1 antagonisten gegen männliche sterilität | |
| BR0206960A (pt) | Composição farmacêutica oral, e, uso de um polìmero de ftalato de hidroxipropilmetilcelulose |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |