ATE243519T1 - Kombinationstherapie der hiv-infektion unter verwendung des hiv-protease inhibitors indinavir und des inhibitors der reversen transkriptase 3 tc zusammen mit azt. - Google Patents

Kombinationstherapie der hiv-infektion unter verwendung des hiv-protease inhibitors indinavir und des inhibitors der reversen transkriptase 3 tc zusammen mit azt.

Info

Publication number: ATE243519T1
Authority: AT; Austria
Prior art keywords: azt; along; hiv; reverse transcriptase; combination therapy
Prior art date: 1995-02-01

Application number

AT96903770T

Other languages

English (en)

Inventor

Jeffrey A Chodakewitz

Emilio A Emini

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-01

Filing date

1996-01-29

Publication date

2003-07-15

1996-01-29 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2003-07-15 Application granted granted Critical

2003-07-15 Publication of ATE243519T1 publication Critical patent/ATE243519T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Plant Substances (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT96903770T 1995-02-01 1996-01-29 Kombinationstherapie der hiv-infektion unter verwendung des hiv-protease inhibitors indinavir und des inhibitors der reversen transkriptase 3 tc zusammen mit azt. ATE243519T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/382,113 US6689761B1 (en)	1995-02-01	1995-02-01	Combination therapy for HIV infection
PCT/US1996/001417 WO1996023509A1 (en)	1995-02-01	1996-01-29	Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc, optionally together with azt, ddi or ddc

Publications (1)

Publication Number	Publication Date
ATE243519T1 true ATE243519T1 (de)	2003-07-15

Family

ID=23507574

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96903770T ATE243519T1 (de)	1995-02-01	1996-01-29	Kombinationstherapie der hiv-infektion unter verwendung des hiv-protease inhibitors indinavir und des inhibitors der reversen transkriptase 3 tc zusammen mit azt.

Country Status (38)

Country	Link
US (1)	US6689761B1 (de)
EP (1)	EP0806957B1 (de)
JP (1)	JPH10513186A (de)
KR (1)	KR19980701856A (de)
CN (1)	CN1160081C (de)
AR (1)	AR002957A1 (de)
AT (1)	ATE243519T1 (de)
AU (1)	AU711176B2 (de)
BR (1)	BR9607714A (de)
CA (1)	CA2211973A1 (de)
CO (1)	CO4700430A1 (de)
CZ (1)	CZ244497A3 (de)
DE (1)	DE69628819T2 (de)
DK (1)	DK0806957T3 (de)
DZ (1)	DZ1988A1 (de)
EA (1)	EA000437B1 (de)
EE (1)	EE03514B1 (de)
ES (1)	ES2200052T3 (de)
FI (1)	FI973184A (de)
HK (1)	HK1004659A1 (de)
HR (1)	HRP960045B1 (de)
HU (1)	HUP9800810A3 (de)
IL (1)	IL116925A (de)
IS (1)	IS1970B (de)
MX (1)	MX9705916A (de)
MY (1)	MY121604A (de)
NO (1)	NO314568B1 (de)
NZ (1)	NZ302153A (de)
PE (1)	PE38397A1 (de)
PL (1)	PL182742B1 (de)
PT (1)	PT806957E (de)
SA (1)	SA96160669B1 (de)
SK (1)	SK103797A3 (de)
TR (1)	TR199700735T1 (de)
TW (1)	TW442291B (de)
WO (1)	WO1996023509A1 (de)
YU (1)	YU49417B (de)
ZA (1)	ZA96722B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998008539A1 (en) *	1996-08-26	1998-03-05	Chiron Corporation	Postinfection human immunodeficiency virus (hiv) vaccination therapy
AU6761198A (en) *	1998-03-17	1999-10-11	Julianna Lisziwiewicz	Anti-hiv combination comprising hydroxyurea, ddi, and a protease inhibitor
US6875773B1 (en)	1998-05-29	2005-04-05	Ben M. Dunn	Combination therapy for treatment of FIV infection
CA2374198A1 (en) *	1998-05-29	1999-12-02	Maki Arai	Combination therapy for treatment of fiv infection
JP2003523721A (ja)	1998-12-31	2003-08-12	カイロンコーポレイション	抗原性ｈｉｖｃ型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
JP5033303B2 (ja)	2001-07-05	2012-09-26	ノバルティスバクシンズアンドダイアグノスティックス，インコーポレーテッド	抗原性ｃ型ｈｉｖポリペプチドをコードするポリヌクレオチド、ポリペプチドおよびそれらの使用
CA2583195A1 (en) *	2004-11-19	2006-05-26	Boehringer Ingelheim International Gmbh	Method for treating hiv infection through co-administration of tipranavir and reverset
AU2006274455B2 (en) *	2005-07-27	2011-06-09	Emil Toma	Zalcitabine (DDC) boosted lamivudine (3TC) compositions for antiretroviral therapy
WO2018128993A1 (en) *	2017-01-04	2018-07-12	Oyagen, Inc.	Compounds, compositions, and methods for treating human immunodeficiency virus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4724232A (en) *	1985-03-16	1988-02-09	Burroughs Wellcome Co.	Treatment of human viral infections
US5254539A (en) *	1985-08-26	1993-10-19	U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health	Method of treating HIV with 2',3'-dideoxyinosine
US5028595A (en) *	1987-09-18	1991-07-02	Hoffmann-La Roche Inc.	Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus
US5204466A (en)	1990-02-01	1993-04-20	Emory University	Method and compositions for the synthesis of bch-189 and related compounds
IL100502A (en)	1991-01-03	1995-12-08	Iaf Biochem Int	PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
US5413999A (en) *	1991-11-08	1995-05-09	Merck & Co., Inc.	HIV protease inhibitors useful for the treatment of AIDS
KR100311551B1 (ko)	1993-03-31	2001-12-28	폴락 돈나 엘.	Aids 치료용 약제학적 배합물 중의 hiv 프로테아제 억제제
IL114208A0 (en)	1994-06-27	1995-10-31	Merck & Co Inc	Combinations of compounds pharmaceutical compositions containing them and their use as hiv protease inhibitors

1995
- 1995-02-01 US US08/382,113 patent/US6689761B1/en not_active Expired - Fee Related
1996
- 1996-01-26 IL IL11692596A patent/IL116925A/xx not_active IP Right Cessation
- 1996-01-29 KR KR1019970705253A patent/KR19980701856A/ko not_active Application Discontinuation
- 1996-01-29 JP JP8523739A patent/JPH10513186A/ja not_active Withdrawn
- 1996-01-29 TR TR97/00735T patent/TR199700735T1/xx unknown
- 1996-01-29 WO PCT/US1996/001417 patent/WO1996023509A1/en not_active Application Discontinuation
- 1996-01-29 CZ CZ972444A patent/CZ244497A3/cs unknown
- 1996-01-29 HU HU9800810A patent/HUP9800810A3/hu unknown
- 1996-01-29 SK SK1037-97A patent/SK103797A3/sk unknown
- 1996-01-29 MX MX9705916A patent/MX9705916A/es not_active IP Right Cessation
- 1996-01-29 CN CNB961929103A patent/CN1160081C/zh not_active Expired - Fee Related
- 1996-01-29 AT AT96903770T patent/ATE243519T1/de not_active IP Right Cessation
- 1996-01-29 BR BR9607714A patent/BR9607714A/pt not_active Application Discontinuation
- 1996-01-29 CA CA002211973A patent/CA2211973A1/en not_active Abandoned
- 1996-01-29 AU AU47748/96A patent/AU711176B2/en not_active Ceased
- 1996-01-29 NZ NZ302153A patent/NZ302153A/xx unknown
- 1996-01-29 DE DE69628819T patent/DE69628819T2/de not_active Expired - Fee Related
- 1996-01-29 EE EE9700165A patent/EE03514B1/xx not_active IP Right Cessation
- 1996-01-29 ES ES96903770T patent/ES2200052T3/es not_active Expired - Lifetime
- 1996-01-29 DK DK96903770T patent/DK0806957T3/da active
- 1996-01-29 PT PT96903770T patent/PT806957E/pt unknown
- 1996-01-29 EA EA199700150A patent/EA000437B1/ru not_active IP Right Cessation
- 1996-01-29 EP EP96903770A patent/EP0806957B1/de not_active Expired - Lifetime
- 1996-01-30 HR HR960045A patent/HRP960045B1/xx not_active IP Right Cessation
- 1996-01-31 ZA ZA96722A patent/ZA96722B/xx unknown
- 1996-01-31 DZ DZ960029A patent/DZ1988A1/fr active
- 1996-01-31 AR ARP960101221A patent/AR002957A1/es unknown
- 1996-01-31 MY MYPI96000349A patent/MY121604A/en unknown
- 1996-01-31 PE PE1996000073A patent/PE38397A1/es not_active Application Discontinuation
- 1996-02-01 YU YU6396A patent/YU49417B/sh unknown
- 1996-02-01 CO CO96004316A patent/CO4700430A1/es unknown
- 1996-02-06 TW TW085101447A patent/TW442291B/zh not_active IP Right Cessation
- 1996-03-12 SA SA96160669A patent/SA96160669B1/ar unknown
1997
- 1997-07-29 IS IS4533A patent/IS1970B/is unknown
- 1997-07-31 NO NO19973533A patent/NO314568B1/no not_active IP Right Cessation
- 1997-07-31 FI FI973184A patent/FI973184A/fi not_active Application Discontinuation
- 1997-09-29 PL PL96321660A patent/PL182742B1/pl unknown
1998
- 1998-05-06 HK HK98103882A patent/HK1004659A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ZA96722B (en)	1996-08-26
KR19980701856A (ko)	1998-06-25
US6689761B1 (en)	2004-02-10
NO973533L (no)	1997-10-01
PL321660A1 (en)	1997-12-22
SA96160669B1 (ar)	2006-07-30
CO4700430A1 (es)	1998-12-29
ES2200052T3 (es)	2004-03-01
IL116925A (en)	2000-07-26
CZ244497A3 (cs)	1998-01-14
HK1004659A1 (en)	1998-12-04
IS1970B (is)	2004-12-15
CN1179722A (zh)	1998-04-22
IS4533A (is)	1997-07-29
NO314568B1 (no)	2003-04-14
EP0806957B1 (de)	2003-06-25
DZ1988A1 (fr)	2002-07-20
AR002957A1 (es)	1998-05-27
AU711176B2 (en)	1999-10-07
BR9607714A (pt)	1998-01-13
CN1160081C (zh)	2004-08-04
SK103797A3 (en)	1998-02-04
DK0806957T3 (da)	2003-09-29
EA000437B1 (ru)	1999-08-26
NZ302153A (en)	1998-12-23
EE03514B1 (et)	2001-10-15
AU4774896A (en)	1996-08-21
HUP9800810A3 (en)	2001-05-28
YU49417B (sh)	2006-01-16
DE69628819T2 (de)	2004-05-13
NO973533D0 (no)	1997-07-31
YU6396A (sh)	1999-06-15
EE9700165A (et)	1998-02-16
WO1996023509A1 (en)	1996-08-08
EA199700150A1 (ru)	1997-12-30
HRP960045B1 (en)	2004-06-30
PT806957E (pt)	2003-10-31
EP0806957A1 (de)	1997-11-19
FI973184A0 (fi)	1997-07-31
HRP960045A2 (en)	1997-10-31
JPH10513186A (ja)	1998-12-15
TW442291B (en)	2001-06-23
MY121604A (en)	2006-02-28
MX9705916A (es)	1997-10-31
PL182742B1 (pl)	2002-02-28
IL116925A0 (en)	1996-05-14
HUP9800810A2 (hu)	1998-07-28
PE38397A1 (es)	1997-10-09
DE69628819D1 (de)	2003-07-31
TR199700735T1 (xx)	1998-02-21
CA2211973A1 (en)	1996-08-08
FI973184A (fi)	1997-09-30

Publication	Publication Date	Title
FI953954A (fi)	1995-08-23	HIV:n käänteistranskriptaasin inhibiittoreita
NO954427D0 (no)	1995-11-06	Hiv-proteaseinhibitorer som er anvendbare for behandling av AIDS
EE03741B1 (et)	2002-06-17	N-propargüül-1-aminoindaani R-enantiomeeri, sellesoolade ja kompositsioonide kasutamine
NO982556D0 (no)	1998-06-04	Behandling av CNS-virkningene av HIV med VX-478, alene eller i kombinasjon med AZT eller 3TC
BR9406209A (pt)	1996-02-06	Derivados heterociclicos no tratamento de isquemia e doenças relacionadas
ATE82574T1 (de)	1992-12-15	Bis-aza-bicyclische anxiolytica und antidepressiva.
DE3671434D1 (de)	1990-06-28	Phenylalaninderivate und proteinaseinhibitor.
DE58901663D1 (de)	1992-07-23	I.m. injektionsformen von gyrase-inhibitoren.
ATE243519T1 (de)	2003-07-15	Kombinationstherapie der hiv-infektion unter verwendung des hiv-protease inhibitors indinavir und des inhibitors der reversen transkriptase 3 tc zusammen mit azt.
DE3772315D1 (de)	1991-09-26	N-tetrazolyl-thiazolcarboxamid-derivate und ihre anwendung.
NO960775D0 (no)	1996-02-26	Anvendelse av kinoksaliner i kombinasjon med proteaseinhibitorer som legemiddel for behandling av AIDS og/eller HIV-infeksjoner
FI945199A0 (fi)	1994-11-04	HIV-käänteiskopioijaentsyymin uudet kinatsoliini-inhibiittorit
MX9203459A (es)	1992-08-01	Nuevos derivados de 2'-halometilideno, 2'-etenilideno y 2'-etinilcitidina, uridina y guanosina.
FI935780A (fi)	1994-06-23	HIV-proteaasin inhibiittoreita, jotka ovat hyödyllisiä AIDSin hoitoa varten
DE58902899D1 (de)	1993-01-14	2',3'-dideoxypurinnucleosid/purinnucleosid-phosphorylase-inhibitor kombinationstherapie und zusammensetzungen dafuer.
NO169052C (no)	1992-05-06	Hydraulisk hammer og anvendelse av samme
DE69010049D1 (de)	1994-07-28	Koproduktion von Propandiamin und alkylierten Aminopropylaminen.
NO904016L (no)	1991-03-18	Paafoerings-hjelpemiddel samt anvendelse av dette.
FI952018A (fi)	1995-04-27	BHAP-yhdisteiden käyttö yhdessä muiden ei-nukleosidi-käänteistransskriptaasi-inhibiittoreiden kanssa HIV-infektion hoitoon
DE3886155D1 (de)	1994-01-20	Anthracyclin-Derivate mit Inhibitorwirkung gegen die reverse Transkriptase des menschlichen Immundefizienzvirus.
MX9201635A (es)	1992-10-01	Derivados de indol y di hidro quinolina.
NO306402B1 (no)	1999-11-01	3-arylalkenyl-1,2,4-oksadiazolderivater og deres anvendelse, samt mellomprodukter for oppnaaelse av derivatene
DK161124C (da)	1991-11-25	Fremgangsmaade og vaerktoej til koldtryksvejsning samt anvendelse af fremgangsmaaden
KR900007413A (ko)	1990-06-01	에이즈 발병방지, 치료제 및 그 치료용 조성물
DE68911383D1 (de)	1994-01-27	Mitomycinderivate und Zwischenprodukte dafür.

Legal Events

Date	Code	Title	Description
2004-01-15	UEP	Publication of translation of european patent specification	Ref document number: 0806957 Country of ref document: EP
2005-04-15	REN	Ceased due to non-payment of the annual fee

Date

Code

Title

Description

2004-01-15

UEP

Publication of translation of european patent specification

Ref document number: 0806957

Country of ref document: EP

2005-04-15

REN

Ceased due to non-payment of the annual fee