NO910735L - Krystallinsk salt av 4-(di-n-propyl)amino-6-aminokarbonyl-1,2,3,4,5-tetrahydrobenz(cd)indolhippurat - Google Patents

Krystallinsk salt av 4-(di-n-propyl)amino-6-aminokarbonyl-1,2,3,4,5-tetrahydrobenz(cd)indolhippurat

Info

Publication number: NO910735L
Authority: NO; Norway
Prior art keywords: aminocarbonyl; propyl; amino; tetrahydrobenze; indolhippurate
Prior art date: 1990-02-26

Application number

NO91910735A

Other languages

English (en)

Other versions

NO910735D0 (no

NO174149B (no

NO174149C (no

Inventor

Thomas Joseph Kress

David Lee Varie

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-26

Filing date

1991-02-25

Publication date

1991-08-27

1991-02-25 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1991-02-25 Publication of NO910735D0 publication Critical patent/NO910735D0/no

1991-08-27 Publication of NO910735L publication Critical patent/NO910735L/no

1993-12-13 Publication of NO174149B publication Critical patent/NO174149B/no

1994-03-23 Publication of NO174149C publication Critical patent/NO174149C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Addiction (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO910735A 1990-02-26 1991-02-25 Fremgangsmåte for fremstilling av 4-(di-n-propyl)-amino-6-aminokarbonyl-1,3,4,5-tetrahydrobenz-(cd)indolhippurat NO174149C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US48518590A	1990-02-26	1990-02-26

Publications (4)

Publication Number	Publication Date
NO910735D0 NO910735D0 (no)	1991-02-25
NO910735L true NO910735L (no)	1991-08-27
NO174149B NO174149B (no)	1993-12-13
NO174149C NO174149C (no)	1994-03-23

Family

ID=23927224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO910735A NO174149C (no)	1990-02-26	1991-02-25	Fremgangsmåte for fremstilling av 4-(di-n-propyl)-amino-6-aminokarbonyl-1,3,4,5-tetrahydrobenz-(cd)indolhippurat

Country Status (28)

Country	Link
US (1)	US5397799A (no)
EP (1)	EP0444852B1 (no)
JP (1)	JP3157007B2 (no)
KR (1)	KR100208114B1 (no)
CN (1)	CN1027503C (no)
AT (1)	ATE126506T1 (no)
AU (1)	AU629453B2 (no)
BR (1)	BR9100767A (no)
CA (1)	CA2037099C (no)
CY (1)	CY1887A (no)
DE (1)	DE69112099T2 (no)
DK (1)	DK0444852T3 (no)
ES (1)	ES2077796T3 (no)
FI (1)	FI95464C (no)
GR (1)	GR3017940T3 (no)
HK (1)	HK175495A (no)
HU (1)	HU217118B (no)
IE (1)	IE67801B1 (no)
IL (1)	IL97306A (no)
LV (1)	LV10251B (no)
NO (1)	NO174149C (no)
NZ (1)	NZ237181A (no)
PT (1)	PT96852B (no)
RU (2)	RU2034837C1 (no)
SG (1)	SG69975A1 (no)
TW (1)	TW219933B (no)
YU (1)	YU47594B (no)
ZA (1)	ZA911258B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL97308A (en) *	1990-02-26	1996-10-31	Lilly Co Eli	Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
US5302612A (en) *	1990-02-26	1994-04-12	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
IL97309A (en) *	1990-02-26	1996-11-14	Lilly Co Eli	Intermediates for hexahydrobenz] [DC indoles and a process for making their pure enantiomers
US5641794A (en) *	1991-03-28	1997-06-24	Eli Lilly Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5364856A (en) *	1991-03-28	1994-11-15	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
TW248556B (no) *	1993-01-18	1995-06-01	Takeda Pharm Industry Co
US7588924B2 (en)	2006-03-07	2009-09-15	Procter & Gamble Company	Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
HUE041300T2 (hu)	2006-06-26	2019-05-28	Akebia Therapeutics Inc	Prolilhidroxiláz inhibitorok és alkalmazási eljárások
PL2496084T3 (pl)	2009-11-06	2015-09-30	Aerpio Therapeutics Inc	Kompozycje oraz metody leczenia zapalenia jelita grubego
NO2686520T3 (no)	2011-06-06	2018-03-17
CN103717214A (zh)	2011-06-06	2014-04-09	阿克比治疗有限公司	用于稳定低氧诱导因子-2α作为治疗癌症的方法的化合物和组合物
HRP20240319T1 (hr)	2013-06-13	2024-05-24	Akebia Therapeutics, Inc.	Pripravci i postupci za liječenje anemije
KR102495018B1 (ko)	2013-11-15	2023-02-06	아케비아 테라퓨틱스 인코포레이티드	｛[5-(3-클로로페닐)-3-하이드록시피리딘-2-카보닐]아미노｝아세트산의 고체형, 이의 조성물 및 용도
CN107427503A (zh)	2015-01-23	2017-12-01	阿克比治疗有限公司	2‑(5‑(3‑氟苯基)‑3‑羟基吡啶甲酰胺)乙酸的固体形式、其组合物及用途
US11324734B2 (en)	2015-04-01	2022-05-10	Akebia Therapeutics, Inc.	Compositions and methods for treating anemia
AU2019265629B2 (en)	2018-05-09	2024-09-12	Akebia Therapeutics, Inc.	Process for preparing 2-((5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl)amino)acetic acid
US11524939B2 (en)	2019-11-13	2022-12-13	Akebia Therapeutics, Inc.	Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4110339A (en) *	1977-11-25	1978-08-29	Eli Lilly And Company	4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4576959A (en) *	1984-02-06	1986-03-18	Eli Lilly And Company	6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
US4745126A (en) *	1987-03-12	1988-05-17	Eli Lilly And Company	Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3809155A1 (de) *	1988-03-18	1989-09-28	Bayer Ag	1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) *	1989-04-11	1993-04-20	Eli Lilly And Company	Tetrahydrobenz(c,d)indole serotonin agonists
US5229409A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-tetrahydrobenz[cd]indoles

1990
- 1990-06-26 TW TW079105258A patent/TW219933B/zh active
1991
- 1991-02-20 ZA ZA911258A patent/ZA911258B/xx unknown
- 1991-02-20 IL IL9730691A patent/IL97306A/en not_active IP Right Cessation
- 1991-02-21 NZ NZ237181A patent/NZ237181A/en unknown
- 1991-02-22 PT PT96852A patent/PT96852B/pt not_active IP Right Cessation
- 1991-02-22 JP JP05064391A patent/JP3157007B2/ja not_active Expired - Fee Related
- 1991-02-25 NO NO910735A patent/NO174149C/no unknown
- 1991-02-25 HU HU91629A patent/HU217118B/hu unknown
- 1991-02-25 KR KR1019910003029A patent/KR100208114B1/ko not_active IP Right Cessation
- 1991-02-25 IE IE62591A patent/IE67801B1/en not_active IP Right Cessation
- 1991-02-25 AU AU71971/91A patent/AU629453B2/en not_active Ceased
- 1991-02-25 RU SU914894699A patent/RU2034837C1/ru not_active IP Right Cessation
- 1991-02-25 YU YU32791A patent/YU47594B/sh unknown
- 1991-02-25 FI FI910895A patent/FI95464C/fi active
- 1991-02-26 DE DE69112099T patent/DE69112099T2/de not_active Expired - Fee Related
- 1991-02-26 ES ES91301501T patent/ES2077796T3/es not_active Expired - Lifetime
- 1991-02-26 DK DK91301501.2T patent/DK0444852T3/da active
- 1991-02-26 CN CN91101296A patent/CN1027503C/zh not_active Expired - Fee Related
- 1991-02-26 AT AT91301501T patent/ATE126506T1/de not_active IP Right Cessation
- 1991-02-26 EP EP91301501A patent/EP0444852B1/en not_active Expired - Lifetime
- 1991-02-26 CA CA002037099A patent/CA2037099C/en not_active Expired - Fee Related
- 1991-02-26 BR BR919100767A patent/BR9100767A/pt not_active Application Discontinuation
- 1991-02-26 SG SG1996007257A patent/SG69975A1/en unknown
1992
- 1992-12-03 RU RU9292004575A patent/RU2083561C1/ru not_active IP Right Cessation
1993
- 1993-05-19 US US08/064,539 patent/US5397799A/en not_active Expired - Lifetime
- 1993-06-08 LV LVP-93-509A patent/LV10251B/xx unknown
1995
- 1995-11-01 GR GR950403048T patent/GR3017940T3/el unknown
- 1995-11-16 HK HK175495A patent/HK175495A/xx not_active IP Right Cessation
1996
- 1996-04-05 CY CY188796A patent/CY1887A/xx unknown

Also Published As

Publication number	Publication date
RU2034837C1 (ru)	1995-05-10
KR910021375A (ko)	1991-12-20
YU47594B (sh)	1995-10-24
JP3157007B2 (ja)	2001-04-16
CA2037099A1 (en)	1991-08-27
FI95464B (fi)	1995-10-31
CY1887A (en)	1996-04-05
IL97306A0 (en)	1992-05-25
NZ237181A (en)	1992-06-25
NO910735D0 (no)	1991-02-25
RU2083561C1 (ru)	1997-07-10
GR3017940T3 (en)	1996-02-29
DK0444852T3 (da)	1995-12-11
ES2077796T3 (es)	1995-12-01
PT96852A (pt)	1991-10-31
FI910895A (fi)	1991-08-27
EP0444852A2 (en)	1991-09-04
YU32791A (sh)	1994-01-20
FI95464C (fi)	1996-02-12
IE67801B1 (en)	1996-05-01
US5397799A (en)	1995-03-14
SG69975A1 (en)	2000-01-25
KR100208114B1 (ko)	1999-07-15
AU7197191A (en)	1991-08-29
CN1027503C (zh)	1995-01-25
NO174149B (no)	1993-12-13
EP0444852B1 (en)	1995-08-16
LV10251A (lv)	1994-10-20
FI910895A0 (fi)	1991-02-25
TW219933B (no)	1994-02-01
ATE126506T1 (de)	1995-09-15
HK175495A (en)	1995-11-24
PT96852B (pt)	1998-07-31
IE910625A1 (en)	1991-08-28
CA2037099C (en)	2001-09-11
AU629453B2 (en)	1992-10-01
ZA911258B (en)	1992-10-28
IL97306A (en)	1996-10-16
NO174149C (no)	1994-03-23
HUT56542A (en)	1991-09-30
JPH04217662A (ja)	1992-08-07
DE69112099T2 (de)	1996-02-08
LV10251B (en)	1995-04-20
HU217118B (hu)	1999-11-29
DE69112099D1 (de)	1995-09-21
CN1054589A (zh)	1991-09-18
EP0444852A3 (en)	1992-02-19
BR9100767A (pt)	1991-10-29

Publication	Publication Date	Title
NO910735L (no)	1991-08-27	Krystallinsk salt av 4-(di-n-propyl)amino-6-aminokarbonyl-1,2,3,4,5-tetrahydrobenz(cd)indolhippurat
AU6666990A (en)	1991-05-23	Indole derivatives
IE782325L (en)	1979-05-25	TETRAHYDROBENZ £cd\| INDOLES
DK0396083T3 (da)	1995-02-06	Heterocykliske N-oxidderivater af substituerede benzo(5,6)-cycloheptapyridiner, præparater og anvendelsesfremgangsmåder
AU6762687A (en)	1987-07-23	N,s and o-substituted indole derivatives
NO894539L (no)	1990-05-16	Fremgangsmaate for fremstilling av nye 2'-halomethyliden-,2'-ethenyliden- og 2'-ethynylcytidin-, uriden og guanosinderivater.
ES2133303T3 (es)	1999-09-16	1,3,4,5-tetrahidrobenzo(cd)indoles 6-heterociclicos-4-amino.
NO913745D0 (no)	1991-09-24	Fremgangsmaate for fremstilling av 1,3-benzoksazinderivater
RU92004575A (ru)	1995-09-27	Кристаллическая соль 4-(ди-н-пропил) амино-6-аминокарбонил-1,3,4,5-тетрагидробенз (cd) индола и ее 4p и 4s-изомеры
NO901070L (no)	1990-10-01	Fremgangsmaate for fremstilling av tieno-triazolo-diazepin-derivater.
NO893826L (no)	1990-03-28	Fremgangsmaate for fremstilling av 2'-halomethyliden, 2'-ethenyliden og 2'-ethenyladenosinderivater.
AU8240791A (en)	1992-02-20	6-substituted-hexahydrobenz(cd)indoles
NO901071D0 (no)	1990-03-07	Fremgangsmaate for fremstilling av tieno-triazolo-diazepin-derivater.
AU6791790A (en)	1991-06-13	5-(2-methyl-4,4,4-trifluorobutyl-carbamoyl)indole derivatives
NO893713L (no)	1990-03-20	Fremgangsmaate for fremstilling av benzoksazolon-derivater.
AU600934C (en)	1991-11-07	Indole derivatives and their 5-ht antagonist effects
PL286424A1 (en)	1992-06-26	Method of obtaining novel indole derivatives
AU7004987A (en)	1987-09-24	Indole derivatives and their 5-ht antagonist effects
PL274219A1 (en)	1990-02-19	Method of obtaining novel derivatives of 4-oxo-1,2,3,4-tetrahydrocinnoline
PL297066A1 (en)	1993-08-23	Method of obtaining indole derivatives