NO326878B1 - Anvendelse av morfolinol - Google Patents

Anvendelse av morfolinol Download PDF

Info

Publication number: NO326878B1
Authority: NO; Norway
Prior art keywords: morpholinol; chlorophenyl; formula; compound; trimethyl
Prior art date: 1998-01-21

Application number

NO20003721A

Other languages

English (en)

Norwegian (no)

Other versions

NO20003721L (no

NO20003721D0 (no

Inventor

David Lee Musso

Phillip Frederick Morgan

John Joseph Partidge

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-21

Filing date

2000-07-20

Publication date

2009-03-09

1998-01-21 Priority claimed from GBGB9801230.5A external-priority patent/GB9801230D0/en

2000-07-20 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2000-07-20 Publication of NO20003721D0 publication Critical patent/NO20003721D0/no

2000-09-19 Publication of NO20003721L publication Critical patent/NO20003721L/no

2009-03-09 Publication of NO326878B1 publication Critical patent/NO326878B1/no

Links

OURXRFYZEOUCRM-UHFFFAOYSA-N 4-hydroxymorpholine Chemical compound ON1CCOCC1 OURXRFYZEOUCRM-UHFFFAOYSA-N 0.000 title description 12
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150000003839 salts Chemical class 0.000 claims abstract description 8
RCOBKSKAZMVBHT-TVQRCGJNSA-N radafaxine Chemical compound C[C@@H]1NC(C)(C)CO[C@@]1(O)C1=CC=CC(Cl)=C1 RCOBKSKAZMVBHT-TVQRCGJNSA-N 0.000 claims abstract description 7
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SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract description 6
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230000003278 mimic effect Effects 0.000 description 1
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LNOPIUAQISRISI-UHFFFAOYSA-N n'-hydroxy-2-propan-2-ylsulfonylethanimidamide Chemical compound CC(C)S(=O)(=O)CC(N)=NO LNOPIUAQISRISI-UHFFFAOYSA-N 0.000 description 1
KVBGVZZKJNLNJU-UHFFFAOYSA-N naphthalene-2-sulfonic acid Chemical compound C1=CC=CC2=CC(S(=O)(=O)O)=CC=C21 KVBGVZZKJNLNJU-UHFFFAOYSA-N 0.000 description 1
210000001577 neostriatum Anatomy 0.000 description 1
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XXPANQJNYNUNES-UHFFFAOYSA-N nomifensine Chemical compound C12=CC=CC(N)=C2CN(C)CC1C1=CC=CC=C1 XXPANQJNYNUNES-UHFFFAOYSA-N 0.000 description 1
229960001073 nomifensine Drugs 0.000 description 1
239000012074 organic phase Substances 0.000 description 1
229940053544 other antidepressants in atc Drugs 0.000 description 1
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
238000007911 parenteral administration Methods 0.000 description 1
235000010603 pastilles Nutrition 0.000 description 1
230000037361 pathway Effects 0.000 description 1
239000012071 phase Substances 0.000 description 1
YPDVTKJXVHYWFY-UHFFFAOYSA-N phosphoric acid;n'-propan-2-ylpyridine-4-carbohydrazide Chemical compound OP(O)(O)=O.CC(C)NNC(=O)C1=CC=NC=C1 YPDVTKJXVHYWFY-UHFFFAOYSA-N 0.000 description 1
239000006187 pill Substances 0.000 description 1
230000036470 plasma concentration Effects 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
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238000011002 quantification Methods 0.000 description 1
230000005855 radiation Effects 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
238000012552 review Methods 0.000 description 1
229960004889 salicylic acid Drugs 0.000 description 1
238000007493 shaping process Methods 0.000 description 1
230000005586 smoking cessation Effects 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
241000894007 species Species 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000000829 suppository Substances 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
210000000225 synapse Anatomy 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
230000002194 synthesizing effect Effects 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
235000019505 tobacco product Nutrition 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
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239000000196 tragacanth Substances 0.000 description 1
229940116362 tragacanth Drugs 0.000 description 1
239000003029 tricyclic antidepressant agent Substances 0.000 description 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
229910052722 tritium Inorganic materials 0.000 description 1
210000002700 urine Anatomy 0.000 description 1
238000005406 washing Methods 0.000 description 1
230000004580 weight loss Effects 0.000 description 1
229940018503 zyban Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Epidemiology (AREA)
Psychology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20003721A 1998-01-21 2000-07-20 Anvendelse av morfolinol NO326878B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9801230.5A GB9801230D0 (en)	1998-01-21	1998-01-21	Pharmaceutically active morpholinol
US7218098P	1998-01-22	1998-01-22
PCT/US1999/001134 WO1999037305A1 (en)	1998-01-21	1999-01-20	Pharmaceutically active morpholinol

Publications (3)

Publication Number	Publication Date
NO20003721D0 NO20003721D0 (no)	2000-07-20
NO20003721L NO20003721L (no)	2000-09-19
NO326878B1 true NO326878B1 (no)	2009-03-09

Family

ID=26312986

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20003721A NO326878B1 (no)	1998-01-21	2000-07-20	Anvendelse av morfolinol
NO20083529A NO20083529L (no)	1998-01-21	2008-08-14	Farmasoytisk aktivt morfolinol

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20083529A NO20083529L (no)	1998-01-21	2008-08-14	Farmasoytisk aktivt morfolinol

Country Status (30)

Country	Link
US (2)	US6274579B1 (xx)
EP (2)	EP1047428B1 (xx)
JP (1)	JP2002501025A (xx)
KR (1)	KR100568063B1 (xx)
CN (2)	CN1203858C (xx)
AP (1)	AP1229A (xx)
AT (1)	ATE365042T1 (xx)
AU (1)	AU755536B2 (xx)
BR (1)	BR9907203A (xx)
CA (1)	CA2318268A1 (xx)
CY (1)	CY1106828T1 (xx)
DE (1)	DE69936335T2 (xx)
DK (1)	DK1047428T3 (xx)
EA (1)	EA002410B1 (xx)
EE (1)	EE04452B1 (xx)
ES (1)	ES2288012T3 (xx)
HR (2)	HRP20000494B1 (xx)
HU (1)	HUP0100900A3 (xx)
ID (1)	ID26334A (xx)
IL (2)	IL137346A0 (xx)
IS (1)	IS2494B (xx)
NO (2)	NO326878B1 (xx)
NZ (3)	NZ520349A (xx)
PL (1)	PL193622B1 (xx)
PT (1)	PT1047428E (xx)
SG (1)	SG115489A1 (xx)
SK (1)	SK10912000A3 (xx)
TR (1)	TR200002126T2 (xx)
WO (1)	WO1999037305A1 (xx)
YU (1)	YU67102A (xx)

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GB0327195D0 (en) *	2003-11-21	2003-12-24	Smithkline Beecham Corp	Novel use
GB0327619D0 (en) *	2003-11-27	2003-12-31	Smithkline Beecham Corp	New use
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EP1734955A2 (en)	2004-01-13	2006-12-27	Duke University	Compositions of an anticonvulsant and an antipsychotic drug for affecting weigt loss
CA2565154A1 (en) *	2004-05-03	2005-11-24	Duke University	Compositions for affecting weight loss
FI117283B (fi)	2005-02-04	2006-08-31	Kone Corp	Hissijärjestelmä
ES2402522T3 (es)	2005-11-22	2013-05-06	Orexigen Therapeutics, Inc.	Composiciones y procedimientos para aumentar la sensibilidad a la insulina
WO2007079470A2 (en)	2006-01-03	2007-07-12	Algebra, Inc.	Therapeutic amine-arylsulfonamide conjugate compounds
US8916195B2 (en)	2006-06-05	2014-12-23	Orexigen Therapeutics, Inc.	Sustained release formulation of naltrexone
KR101479324B1 (ko)	2006-11-09	2015-01-05	오렉시젠 세러퓨틱스 인크.	신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형
AU2007319472B2 (en)	2006-11-09	2013-01-17	Nalpropion Pharmaceuticals Llc	Methods Of Administering Weight Loss Medications
US20090075994A1 (en) *	2007-09-14	2009-03-19	Protia, Llc	Deuterium-enriched radafaxine
CA2725930A1 (en)	2008-05-30	2009-12-30	Orexigen Therapeutics, Inc.	Methods for treating visceral fat conditions
CA2758774C (en)	2009-04-15	2015-02-03	Research Triangle Institute	Monoamine reuptake inhibitors
AU2011203867B2 (en)	2010-01-11	2015-12-03	Nalpropion Pharmaceuticals Llc	Methods of providing weight loss therapy in patients with major depression
EP2571859B1 (en)	2010-05-21	2015-07-22	Research Triangle Institute	1-phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
ES2687095T3 (es)	2010-05-21	2018-10-23	Research Triangle Institute	Fenilimorfolinas y análogos de las mismas
US9510405B2 (en)	2011-06-30	2016-11-29	Schneider Electric Industries Sas	Dual power SMPS for a modular lighting system
CN102670617B (zh) *	2012-04-13	2013-03-20	湖南大学	布洛芬2-（2-芳基吗啉-4-基）乙酯作为制备抗抑郁药物的应用
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CN105949142B (zh) *	2016-05-21	2018-03-27	南华大学	具有抗抑郁活性的单一手性化合物及其制备方法和应用
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1999
- 1999-01-20 NZ NZ520349A patent/NZ520349A/en unknown
- 1999-01-20 HU HU0100900A patent/HUP0100900A3/hu unknown
- 1999-01-20 IL IL13734699A patent/IL137346A0/xx not_active IP Right Cessation
- 1999-01-20 AP APAP/P/2000/001869A patent/AP1229A/en active
- 1999-01-20 IL IL16194299A patent/IL161942A0/xx unknown
- 1999-01-20 EA EA200000691A patent/EA002410B1/ru not_active IP Right Cessation
- 1999-01-20 SK SK1091-2000A patent/SK10912000A3/sk unknown
- 1999-01-20 EE EEP200000438A patent/EE04452B1/xx not_active IP Right Cessation
- 1999-01-20 AU AU23280/99A patent/AU755536B2/en not_active Ceased
- 1999-01-20 CN CNB998042706A patent/CN1203858C/zh not_active Expired - Fee Related
- 1999-01-20 NZ NZ529316A patent/NZ529316A/en unknown
- 1999-01-20 JP JP2000528287A patent/JP2002501025A/ja active Pending
- 1999-01-20 KR KR1020007007996A patent/KR100568063B1/ko not_active IP Right Cessation
- 1999-01-20 TR TR2000/02126T patent/TR200002126T2/xx unknown
- 1999-01-20 SG SG200204411A patent/SG115489A1/en unknown
- 1999-01-20 PL PL99342012A patent/PL193622B1/pl not_active IP Right Cessation
- 1999-01-20 US US09/233,531 patent/US6274579B1/en not_active Expired - Fee Related
- 1999-01-20 EP EP99903200A patent/EP1047428B1/en not_active Expired - Lifetime
- 1999-01-20 ID IDW20001597A patent/ID26334A/id unknown
- 1999-01-20 ES ES99903200T patent/ES2288012T3/es not_active Expired - Lifetime
- 1999-01-20 DK DK99903200T patent/DK1047428T3/da active
- 1999-01-20 BR BR9907203-3A patent/BR9907203A/pt not_active Application Discontinuation
- 1999-01-20 PT PT99903200T patent/PT1047428E/pt unknown
- 1999-01-20 NZ NZ505809A patent/NZ505809A/xx unknown
- 1999-01-20 CN CNB2004100085595A patent/CN1255389C/zh not_active Expired - Fee Related
- 1999-01-20 AT AT99903200T patent/ATE365042T1/de active
- 1999-01-20 DE DE69936335T patent/DE69936335T2/de not_active Expired - Lifetime
- 1999-01-20 CA CA002318268A patent/CA2318268A1/en not_active Abandoned
- 1999-01-20 EP EP07110283A patent/EP1829544A1/en not_active Withdrawn
- 1999-01-20 WO PCT/US1999/001134 patent/WO1999037305A1/en active IP Right Grant
2000
- 2000-07-20 NO NO20003721A patent/NO326878B1/no not_active IP Right Cessation
- 2000-07-20 IS IS5568A patent/IS2494B/is unknown
- 2000-07-21 HR HR20000494A patent/HRP20000494B1/xx not_active IP Right Cessation
2001
- 2001-06-22 US US09/886,391 patent/US6391875B2/en not_active Expired - Fee Related
2002
- 2002-09-06 YU YU67102A patent/YU67102A/sh unknown
2005
- 2005-12-29 HR HR20051024A patent/HRP20051024A2/hr not_active Application Discontinuation
2007
- 2007-08-31 CY CY20071101117T patent/CY1106828T1/el unknown
2008
- 2008-08-14 NO NO20083529A patent/NO20083529L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EE04452B1 (et)	2005-04-15
NO20083529L (no)	2000-09-19
DE69936335D1 (de)	2007-08-02
HRP20000494A2 (en)	2000-12-31
CA2318268A1 (en)	1999-07-29
HRP20000494B1 (en)	2009-02-28
US20020019396A1 (en)	2002-02-14
ES2288012T3 (es)	2007-12-16
EP1829544A1 (en)	2007-09-05
HRP20051024A2 (hr)	2006-04-30
HUP0100900A3 (en)	2002-08-28
CN1528753A (zh)	2004-09-15
TR200002126T2 (tr)	2000-12-21
PT1047428E (pt)	2007-09-07
EE200000438A (et)	2001-12-17
HUP0100900A2 (hu)	2002-05-29
US6274579B1 (en)	2001-08-14
IS5568A (is)	2000-07-20
SK10912000A3 (sk)	2001-04-09
NO20003721L (no)	2000-09-19
KR100568063B1 (ko)	2006-04-07
WO1999037305A1 (en)	1999-07-29
PL193622B1 (pl)	2007-02-28
AU2328099A (en)	1999-08-09
NZ505809A (en)	2002-09-27
EA002410B1 (ru)	2002-04-25
EA200000691A1 (ru)	2001-04-23
AP2000001869A0 (en)	2000-09-30
NZ529316A (en)	2004-05-28
EP1047428B1 (en)	2007-06-20
EP1047428A4 (en)	2001-12-19
IL161942A0 (en)	2005-11-20
US6391875B2 (en)	2002-05-21
NO20003721D0 (no)	2000-07-20
IS2494B (is)	2009-02-15
PL342012A1 (en)	2001-05-07
IL137346A0 (en)	2001-07-24
KR20010034285A (ko)	2001-04-25
ATE365042T1 (de)	2007-07-15
NZ520349A (en)	2004-02-27
SG115489A1 (en)	2005-10-28
DE69936335T2 (de)	2008-02-28
BR9907203A (pt)	2000-10-17
CN1203858C (zh)	2005-06-01
CN1255389C (zh)	2006-05-10
YU67102A (sh)	2004-12-31
CN1294513A (zh)	2001-05-09
AU755536B2 (en)	2002-12-12
DK1047428T3 (da)	2007-10-08
ID26334A (id)	2000-12-14
CY1106828T1 (el)	2012-05-23
EP1047428A1 (en)	2000-11-02
JP2002501025A (ja)	2002-01-15
AP1229A (en)	2003-12-04

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NO326878B1 (no)	2009-03-09	Anvendelse av morfolinol
EP2400967B1 (en)	2019-08-14	Treatment of dyskinesia related disorders
EA006652B1 (ru)	2006-02-24	Высокоселективные ингибиторы обратного захвата норэпинефрина и способы их применения
JP2009531431A (ja)	2009-09-03	認知障害および他の障害の治療方法
US20060189612A1 (en)	2006-08-24	Pharmaceutically active morpholinol
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AU2002315922B2 (en)	2006-06-01	Pharmaceutically active morpholinol
MXPA00007127A (en)	2001-07-09	Pharmaceutically active morpholinol
CZ20002690A3 (cs)	2000-12-13	Farmaceuticky přijatelné soli a solváty (+)- (2S,3S)-2-(3-chlorfenyl)-3,5,5-trimethyl-2- morfolinolu a farmaceutický prostředek
KR20040023653A (ko)	2004-03-18	제약상 활성인 모르폴리놀
Ananth	1983	New antidepressants
US20070004724A1 (en)	2007-01-04	(+)-(2S,3s)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinor for treating anxiety

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